Search clinical trials for: Riboflavin 0.1% ophthalmic solution

Total 2527 results

Lux Biosciences, Inc.

Completed

A Dose-Escalation Study to Assess the Safety and Tolerability of LX214 Ophthalmic Solution in Healthy Volunteers, Followed by an Open-Label Evaluation of LX214 in Patients With Keratoconjunctivitis Sicca (KCS)

Keratoconjunctivitis Sicca

United States
Senju Pharmaceutical Co., Ltd.

Completed

Safety and Efficacy Study of SJP-0035 Ophthalmic Solution in Patients With Moderate to Severe Corneal Epithelial Disorders

Corneal Epithelial Disorders

United States
Santen Inc.

Completed

Study Assessing the Safety and Efficacy of DE-117 Ophthalmic Solution Once Daily and Twice Daily in Subjects With Primary Open-Angle Glaucoma SPECTRUM 6

Primary Open-angle Glaucoma and Ocular Hypertension

United States
Senju Pharmaceutical Co., Ltd.

Completed

Safety and Efficacy of SJP-0035 Ophthalmic Solution in Patients With Moderate to Severe Corneal Epithelial Disorders

Corneal Epithelial Disorders

United States
Aerie Pharmaceuticals

Completed

Double-masked Study of PG324 Ophthalmic Solution in Patients With Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-angle Glaucoma

United States
Aerie Pharmaceuticals

Completed

Double-masked Study of PG324 Ophthalmic Solution in Patients With Open-angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-angle Glaucoma

United States
Alcon Research

Withdrawn

Safety and Efficacy of AL-15469A 0.5% / AL-6515 0.3% Ophthalmic Suspension for Treatment of Bacterial Conjunctivitis

Bacterial Conjunctivitis
Johns Hopkins University

Completed

Study of Ocular Penetration of Topically Administered Fluoroquinolones

Cataract Extraction

United States
Santen Pharmaceutical Co., Ltd.

Completed

DE-111 Against Tafluprost Ophthalmic Solution 0.0015% Alone and Concomitant Use of Tafluprost Ophthalmic Solution 0.0015% Plus Timolol Ophthalmic Solution 0.5%

Ocular Hypertension | Open Angle Glaucoma

Japan
Allergan

Completed

Safety and Efficacy of Bimatoprost Ophthalmic Solution in Increasing Eyelash Prominence

Eyelash Hypotrichosis

United States
Santen Pharmaceutical Co., Ltd.

Recruiting

A Long Term Study of STN1012600 in Subjects With Open Angle Glaucoma or Ocular Hypertension

Open Angle Glaucoma, Ocular Hypertension

Japan
Cornea and Laser Eye Institute

Active, not recruiting

Corneal Collagen Crosslinking for Progressive Keratoconus and Ectasia Using Riboflavin/Dextran and Hypotonic Riboflavin

Keratoconus | Corneal Ectasia

United States
Santen Inc.

Completed

Multi-center Phase II Study Assessing the Safety and Efficacy of DE-117 Ophthalmic Solution in Subjects With Primary Open-angle Glaucoma or Ocular Hypertension (SEE-1)

Ocular Hypertension | Open-angle Glaucoma

United States
University of California, Los Angeles
Novartis

Recruiting

Treatment of Ocular Discomfort in Glaucoma Patients Using Multiple Topical Medications

Glaucoma | Ocular Surface Disease

United States
Avizorex Pharma, S.L.

Unknown

Assessing the Safety and Efficacy of AVX-012 in Subjects With Mild-to-moderate Dry Eye Syndrome (AVX012CT001)

Dry Eye Syndrome

Spain
HanAll BioPharma Co., Ltd.

Completed

A Study to Assess Efficacy of HL036 in Subjects With Dry Eyes (VELOS-1)

Dry Eye

United States
Minnesota Eye Consultants, P.A.
Bausch & Lomb Incorporated

Completed

The Effect of BEPREVE 1.5% on Tear Film Osmolarity and Tear Film Lipid Layer

Allergic Conjunctivitis

United States
Qlaris Bio, Inc.

Not yet recruiting

Qlaris Phase 2 Study in NTG Patients

Glaucoma | Normal Tension Glaucoma (NTG) | Low-Tension Glaucoma, Bilateral | Low-Tension Glaucoma, Unspecified Eye

Korea, Republic of, Philippines
Shandong University

Unknown

Different Lugol's Solution Concentration for Image Quality of Esophageal Lesions in Chromoendoscopy With Iodine Staining

Image Quality of Early Esophageal Squamous Neoplasia | Endoscopists'Subjective Assessments

China
ONL Therapeutics

Active, not recruiting

A Phase 1b Study of ONL1204 Ophthalmic Solution in Patients With Progressing Open Angle Glaucoma

Open Angle Glaucoma

Australia, New Zealand
Parion Sciences

Terminated

Evaluation of P-321 Ophthalmic Solution Compared to Placebo in Subjects With Dry Eye Disease

Dry Eye Disease

United States
Parion Sciences

Completed

Study of the Safety and Tolerability of P 321 Ophthalmic Solution in Subjects With Dry Eye Disease

Dry Eye Disease

United States
Alcon Research

Completed

A Study of Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-Angle Glaucoma
Laboratoires Thea

Completed

Efficacy, Safety of T2769 in Dry Eye Disease

Dry Eye Syndrome

Tunisia
Merck Sharp & Dohme LLC

Completed

Study of INS365 Ophthalmic Solution in a Controlled Adverse Environment in Patients With Dry Eye

Keratoconjunctivitis Sicca
Alcon Research

Completed

Efficacy and Safety of an Ophthalmic Solution in Patients With Allergic Conjunctivitis

Allergic Conjunctivitis
Alcon Research

Completed

Clinical Evaluation of Systane® Gel Drops in Dry Eye Subjects

Dry Eye

India
BRIM Biotechnology Inc.

Not yet recruiting

Assessment of the Safety and Efficacy of BRM424 Ophthalmic Solutions in Patients With Neurotrophic Keratitis

Neurotrophic Keratitis
Kissei Pharmaceutical Co., Ltd.

Terminated

An Extension Study of KCT-0809 in Dry Eye Patients With Sjögren's Syndrome

Dry Eye With Sjögren's Syndrome

Japan
Vistakon Pharmaceuticals

Completed

Evaluation of Efficacy of Ophthalmic Solution in Seasonal Allergic Conjunctivitis

Allergic Conjunctivitis

United States
Santen Inc.

Completed

DE-117 Spectrum 5 Study

Primary Open-angle Glaucoma and Ocular Hypertension

United States
Trefoil Therapeutics, Inc.

Completed

Dose Escalation TTHX1114 Ophthalmic Solution (EPI)

Corneal Epithelial Degeneration

United States
Mimetogen Pharmaceuticals USA, Inc.

Completed

Tavilermide Ophthalmic Solution for the Treatment of Dry Eye

Dry Eye | Keratoconjunctivitis Sicca

United States
Allysta Pharmaceutical

Completed

ALY688 Ophthalmic Solution in Subjects With Dry Eye Disease (OASIS-1)

Dry Eye

United States
Chakshu Research, Inc.

Completed

An Open-Label Study of an Ophthalmic Solution to Reduce Intraocular Pressure in Patients With Ocular Hypertension

Ocular Hypertension

United States
Chakshu Research, Inc.

Unknown

An Open-Label Study of the Effect of an Ophthalmic Solution on Asteroid Hyalosis

Asteroid Hyalosis

United States
Othera Pharmaceuticals

Terminated

Study of OT-551 Eye Drops to Prevent or Delay Progression of Nuclear Cataracts Following Vitreous Removal

Epiretinal Membrane | Macular Hole

United States
Santen Pharmaceutical Co., Ltd.

Completed

Safety and Efficacy Study of DE-104 Ophthalmic Solution to Treat Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-Angle Glaucoma

Japan
Shandong University

Completed

Lower Lugol's Solution Concentration on Reducing the Adverse Symptoms of Chromoendoscopy With Iodine Staining

Image Quality | Mucosal Irritation

China
State University of New York College of Optometry
Novartis Pharmaceuticals

Completed

Lifitegrast 5% for the Treatment of Dry Eye In Habitual Soft Contact Lens Wearers

Dry Eye

United States
BRIM Biotechnology Inc.

Recruiting

Assessment of the Safety and Efficacy of BRM421 Ophthalmic Solutions in Dry Eye Subjects.

Dry Eye Disease

United States
University of California, Los Angeles

Recruiting

Corneal Nerves After Treatment With Cenegermin

Neurotrophic Keratitis

United States
Santen Pharmaceutical Co., Ltd.

Completed

Pharmacokinetic Study of STN1012600 Ophthalmic Solution in Healthy Adult Males Volunteers

Healthy Adult Males Volunteers

Japan
Massachusetts Eye and Ear Infirmary

Completed

Netarsudil Use After Descemetorhexis Without Endothelial Keratoplasty

Cataract | Fuchs' Endothelial Dystrophy

United States
Kissei Pharmaceutical Co., Ltd.

Completed

A Long-term Study of KCT-0809 in Dry Eye Patients With Sjögren's Syndrome

Dry Eye With Sjögren's Syndrome

Japan
Santen Pharmaceutical Co., Ltd.

Completed

DE-111 Ophthalmic Solution in Patients With Open Angle Glaucoma or Ocular Hypertension

Open Angle Glaucoma or Ocular Hypertension

Japan
Santen Pharmaceutical Co., Ltd.

Completed

A Long-term Study of DE-114 Ophthalmic Solution in Patients With Allergic Conjunctivitis

Allergic Conjunctivitis

Japan
Allergan

Completed

Safety and Efficacy of Relestat Ophthalmic Solution 0.05% for Allergic Conjunctivitis in Korea

Conjunctivitis, Allergic

Korea, Republic of
Alcon Research

Completed

Clinical Pharmacological Study of AL-43546 Ophthalmic Product in Subjects With Shortened Tear Film Break Up Time

Dry Eye Disease

Japan
Allergan

Completed

A Safety, Efficacy and Pharmacokinetic Study of AGN-199201 and AGN-190584 in Patients With Presbyopia

Presbyopia

United States

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