Search clinical trials for: Rifamycin SV b.i.d. Placebo

Total 100 results

Dermatology Specialties Limited Partnership

Completed

Dose-Ranging Efficacy and Safety Study of Topical Rapamycin Cream for Facial Angiofibroma Associated With Tuberous Sclerosis Complex

Tuberous Sclerosis | Facial Angiofibroma

United States, Taiwan, Serbia, Spain, Australia, Czechia, Hungary, New Zealand, Slovakia
Aucta Pharmaceuticals, Inc

Terminated

Topical Sirolimus Ointment for Cutaneous Angiofibromas in Subjects With Tuberous Sclerosis Complex

Tuberous Sclerosis | Angiofibroma of Face

United States, China
The University of Texas Health Science Center at...

Withdrawn

Secondary Prevention Trial of Rapamycin in Patients With Resected Non-muscle Invasive Bladder Cancer

Bladder Cancer

United States
State University of New York - Upstate Medical...

Not yet recruiting

Sirolimus Treatment Of Patients With SLE (STOPSLE)

Lupus Erythematosus, Systemic
Boehringer Ingelheim

Completed

A Six-week Study Comparing the Efficacy and Safety of Tiotropium Plus Formoterol to Salmeterol Plus Fluticasone in Chronic Obstructive Pulmonary Disease (COPD)

Pulmonary Disease, Chronic Obstructive

Germany, Netherlands, Denmark, France, South Africa, Austria, Belgium, Sweden
Translumina GmbH

Terminated

Non-Polymer-Based, Rapamycin-Eluting Stents to Prevent Restenosis

Coronary Disease

Germany, Israel, Austria
Katarzyna Kotulska

Recruiting

Efficacy and Safety of Rapamycin Versus Vigabatrin in the Prevention of Tuberous Sclerosis Complex Symptoms in Infants (ViRap)

Tuberous Sclerosis Complex

Poland
Palvella Therapeutics, Inc.

Not yet recruiting

A Phase 3 Randomized, Double-Blind, Placebo-Controlled Study Evaluating Safety and Efficacy of QTORIN 3.9% Rapamycin Anhydrous Gel in the Treatment of Microcystic Lymphatic Malformations (SELVA)

Microcystic Lymphatic Malformation

United States
Yale University

Terminated

Rapamycin as Treatment for Autosomal Dominant Polycystic Kidney Disease (ADPKD): The Role of Biomarkers in Predicting a Response to Therapy

Autosomal Dominant Polycystic Kidney Disease

United States
Maastricht University Medical Center
Myrovlytis Trust

Completed

Topical Rapamycin for Fibrofolliculomas

Birt-Hogg-Dubé Syndrome

Netherlands
Melanoma and Skin Cancer Trials Limited
Monash University; The University of Queensland

Not yet recruiting

Topical Sirolimus in Chemoprevention of Facial Squamous Cell Carcinomas in Solid Organ Transplant Recipients (SiroSkin) (SiroSkin)

Skin Cancer | Solid Organ Transplant Recipients

Australia
Medical University of South Carolina

Completed

Enhancing Self Regulation Among Smokers (MIMIC)

Smoking Cessation | Nicotine Dependence | Smoking, Cigarette

United States
Reckitt Benckiser Healthcare (UK) Limited

Terminated

Compound Sodium Alginate Oral Suspension Sachet 4-hour Esophageal pH Study in GERD Patients

Gastro-esophageal Reflux Disease (GERD)

China
Institut National de la Santé Et de la Recherche...

Completed

Rapamycine vs Placebo for the Treatment of Inclusion Body Myositis (RAPAMI)

Inclusion Body Myositis (IBM)

France
Azienda Ospedaliero-Universitaria di Modena
University of Padova; Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta; University of Turin, Italy and other collaborators

Completed

Rapamycin Treatment for ALS (RAP-ALS)

Amyotrophic Lateral Sclerosis

Italy
Rapamycin Holdings, Inc. dba Emtora Biosciences
National Cancer Institute (NCI)

Recruiting

Trial of Encapsulated Rapamycin (eRapa) for Bladder Cancer Prevention

Non-muscle Invasive Bladder Cancer

United States
AgelessRx
University of California, Los Angeles

Completed

Participatory Evaluation (of) Aging (With) Rapamycin (for) Longevity Study (PEARL)

Aging

United States
Medical University of South Carolina

Completed

Altering Memories That Increase Risk of Relapse in Alcohol Use Disorders

Alcohol Dependence | Alcohol Use Disorder

United States
The University of Texas Health Science Center at...
National Institute on Aging (NIA)

Completed

Topical-RAPA Use in Inflammation Reversal and Re-setting the Epigenetic Clock (Topical-RAPA)

Aging | Epigenetics | Inflammatory Mediators

United States
University of Texas Southwestern Medical Center
North Texas Veterans Healthcare System

Completed

Rapamycin as a Means of Interference With Reconsolidation of Posttraumatic Stress Disorder-related Traumatic Memory

Posttraumatic Stress Disorder

United States
GlaxoSmithKline

Completed

A Comparator Study of Fluticasone Propionate Nasal Spray Verses (vs) Cetirizine in the Treatment of Seasonal Allergic Rhinitis

Rhinitis, Allergic, Perennial and Seasonal

United States
University of Copenhagen
Danish Diabetes Academy

Recruiting

mTOR as Mediator of Insulin Sensitivity Study

Insulin Sensitivity

Denmark
Piemonti Lorenzo
Italian Diabetes Foundation

Completed

Monotherapy With Rapamycin in Long-standing Type 1 Diabetes (MONORAPA)

Diabetes Mellitus, Type 1

Italy
Turku University Hospital

Completed

Effects of Rifampicin on the Pharmacokinetics and Pharmacodynamics of Sublingual and Intravenous Buprenorphine

Healthy

Finland
University of Cape Town

Recruiting

Testing New Strategies for Patients Hospitalised With HIV-associated Disseminated Tuberculosis (NEW-STRAT TB)

HIV | Disseminated Tuberculosis

South Africa
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Terminated

Everolimus in Patients With Pancreatic Neuroendocrine Tumors Metastatic to the Liver Previously Treated With Surgery

Liver Metastases | Gastrinoma | Glucagonoma | Insulinoma | Pancreatic Polypeptide Tumor | Recurrent Islet Cell Carcinoma | Somatostatinoma

United States
Medical University of South Carolina
American Skin Association

Active, not recruiting

Daily Topical Rapamycin for Vitiligo

Vitiligo

United States
Universitas Padjadjaran
Radboud University Medical Center; United States Agency for International Development...

Completed

High-dose Rifampicin for the Treatment of Tuberculous Meningitis: a Dose-finding Study (ReDEFINe)

Tuberculosis, Meningeal

Indonesia
Eleos, Inc.

Withdrawn

Aezea® (Cenersen) and Chemotherapy for AML Subjects ≥ 55 Years of Age With No Response to Frontline Induction Course

Acute Myelogenous Leukemia
Santen Inc.
MacuSight, Inc.

Terminated

Phase 2 Study of an Ocular Sirolimus (Rapamycin) Formulation in Combination With Lucentis® in Patients With Age-Related Macular Degeneration (EMERALD)

Age-Related Macular Degeneration | Choroidal Neovascularization

United States
Dana-Farber Cancer Institute
Wyeth is now a wholly owned subsidiary of Pfizer; PDL BioPharma, Inc.

Terminated

Sirolimus, Mycophenolate Mofetil and Bortezomib as Graft-Versus-Host Disease (GVHD) Prophylaxis After Reduced Intensity Conditioning (RIC) Hematopoietic Stem Cell Transplantation

Graft-vs-Host Disease

United States
Institut d'Investigació Biomèdica de Bellvitge

Recruiting

Effect of Loratadine in Lymphangioleiomyomatosis (LORALAM)

Lymphangioleiomyomatosis

Spain
Vanderbilt University

Completed

Trial of Antimycobacterial Therapy in Sarcoidosis (CLEAR)

Sarcoidosis

United States
GlaxoSmithKline

Completed

Drug-drug Interaction Study of Gepotidacin

Infections, Bacterial

United States
Institut Pasteur
Assistance Publique Hopitaux De Marseille; Ministry of Health, France; Hôpital... and other collaborators

Not yet recruiting

Efficacy of an Adapted Antibiotherapy in Hurley Stage 2 Hidradenitis Suppurativa Patients (ABCESS2)

Hidradenitis Suppurativa

France
Masonic Cancer Center, University of Minnesota

Completed

TBI Dose De-escalation for Fanconi Anemia

Fanconi Anemia

United States
Nottingham University Hospitals NHS Trust

Active, not recruiting

REpurposing SirolimUS in Compensated Advanced Chronic Liver Disease. The RESUS Proof of Concept Study (RESUS)

Advanced Chronic Liver Disease

United Kingdom
Masonic Cancer Center, University of Minnesota

Active, not recruiting

UCB Transplant for Hematological Diseases Using a Non Myeloablative Prep

Follicular Lymphoma | Acute Myeloid Leukemia | Multiple Myeloma | Hodgkin Lymphoma | Lymphoplasmacytic Lymphoma | Acute Leukemia | Myelodysplastic Syndrome | Chronic Myelogenous Leukemia | Prolymphocytic Leukemia | Plasma Cell Leukemia | Bone Marrow Failure Syndromes | Burkitt's Lymphoma | Acute Lymphoblastic Leukemia... and other conditions

United States
Pfizer

Completed

A Study to Learn About the Drug-drug Interactions of Sisunatovir in Healthy Adult Participants

Respiratory Syncytial Virus Infections

United Kingdom
VA Office of Research and Development

Recruiting

Investigation of Rifampin to Reduce Pedal Amputations for Osteomyelitis in Diabetics (VA INTREPID)

Diabetes | Amputation | Osteomyelitis

United States
University of Washington
National Institute of General Medical Sciences (NIGMS)

Completed

CYP3A4 Activity and Mineral Homeostasis

Vitamin D and Calcium Homeostasis

United States
Vanderbilt University
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Phase II Investigation of Antimycobacterial Therapy on Progressive, Pulmonary Sarcoidosis

Sarcoidosis; Antimycobacterial Therapy

United States
GOG Foundation
National Cancer Institute (NCI)

Completed

Bevacizumab With or Without Everolimus in Treating Patients With Recurrent or Persistent Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer

Recurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma

United States
Johns Hopkins University
Case Western Reserve University; Cystic Fibrosis Foundation

Completed

Persistent Methicillin Resistant Staphylococcus Aureus Eradication Protocol (PMEP) (PMEP)

Cystic Fibrosis

United States
Henan University of Traditional Chinese Medicine
Peking University First Hospital; Chengdu University of Traditional Chinese... and other collaborators

Unknown

Study on Children Henoch-Schönlein Purpura Nephritis With TCM Multistep Treatment

Henoch-Schönlein Purpura Nephritis

China
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Itacitinib, Tacrolimus, and Sirolimus for the Prevention of GVHD in Patients With Acute Leukemia, Myelodysplastic Syndrome, or Myelofibrosis Undergoing Reduced Intensity Conditioning Donor Stem Cell Transplantation

Primary Myelofibrosis | Acute Leukemia | Myelodysplastic Syndrome | Secondary Myelofibrosis | Hematologic and Lymphocytic Disorder

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Graft-Versus-Host Disease Prophylaxis in Treating Patients With Hematologic Malignancies Undergoing Unrelated Donor Peripheral Blood Stem Cell Transplant

Hematopoietic and Lymphoid Cell Neoplasm | Diffuse Large B-Cell Lymphoma | Acute Myeloid Leukemia | Refractory Hodgkin Lymphoma | Waldenstrom Macroglobulinemia | Acute Lymphoblastic Leukemia | Mantle Cell Lymphoma | Chronic Lymphocytic Leukemia | Myelodysplastic Syndrome | Prolymphocytic Leukemia | Refractory... and other conditions

United States, Germany, Denmark
Millennium Pharmaceuticals, Inc.

Completed

Pharmacokinetics Study of Oral IXAZOMIB in Participants With Advanced Nonhematologic Malignancies or Lymphoma

Lymphoma | Nonhematologic Malignancies

United States
Assembly Biosciences

Completed

A Study to Assess CYP3A4 Modulator, Oral Contraceptive, and pH Modifier Drug Interactions for ABI-H2158 in Healthy Adults

Chronic Hepatitis B

United States
University of Washington
National Cancer Institute (NCI)

Completed

Early Allogeneic Hematopoietic Cell Transplantation in Treating Patients With Relapsed or Refractory High-Grade Myeloid Neoplasms

Previously Treated Myelodysplastic Syndrome | Myelodysplastic Syndrome | Recurrent Acute Myeloid Leukemia | Refractory Acute Myeloid Leukemia | Myelodysplastic Syndrome With Excess Blasts-2 | Myeloid Neoplasm | Chronic Myelomonocytic Leukemia-2 | Blasts 10 Percent or More of Bone Marrow Nucleated... and other conditions

United States

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