Search clinical trials for: rifapentine & midazolam

Total 1139 results

Vertex Pharmaceuticals Incorporated

Not yet recruiting

A Phase 1, Open-label Study Evaluating the Pharmacokinetics and Drug-drug Interaction of VX-993 in Healthy Adults

Pain
Siriraj Hospital

Recruiting

The Efficacy of P0.1-guided Sedation Protocol in Critically Ill Patients Receiving Invasive Mechanical Ventilation: A Randomized Controlled Trial

Critical Illness | Respiratory Failure | Lung Injury | Respiratory Distress Syndrome, Adult | Mechanical Ventilation Complication

Thailand
Wake Forest University Health Sciences

Recruiting

The Effects of Sedatives on Tobacco Use Disorder Version 2 (SED-TUD2)

Tobacco Smoking

United States
Osijek University Hospital
Josip Juraj Strossmayer University of Osijek

Recruiting

Propofol and Dexmedetomidin vs Midazolam Intraoperative Sedation and POCD (ProDex-POCD)

Postoperative Cognitive Dysfunction | Postoperative Pain, Acute | Pertrochanteric Fracture

Croatia
Bayer

Completed

Drug-drug Interaction Study Between Orally Administered Rifampicin and Vilaprisan

Endometriosis

Germany
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Effect of a Single Dose of CNTO 136 (Sirukumab) on CYP450 Enzyme Activities After Subcutaneous Administration in Patients With Rheumatoid Arthritis

Arthritis, Rheumatoid

Germany, Korea, Republic of, South Africa, Moldova, Republic of
Astellas Pharma Europe B.V.

Completed

First-in-human: Single Ascending Dose, Food Effect, Drug-drug Interaction, Multiple Ascending Dose, Proof of Pharmacology

Healthy Volunteers

United Kingdom, Germany
ViiV Healthcare

Completed

Evaluation of Pharmacokinetic Interaction Between GSK3640254 and Caffeine, Metoprolol, Montelukast, Flurbiprofen, Omeprazole, Midazolam, Digoxin, and Pravastatin in Healthy Adults

HIV Infections

United States
Mercy Facial Plastic Surgery Center

Completed

Anesthetics in Rhytidoplasty - A Comparison Study

Rhytidoplasty

United States
Aeovian Pharmaceuticals, Inc.

Recruiting

Assessment of the Safety, Tolerability and Pharmacokinetics of AV078 in Healthy Volunteers

Healthy Participants

Australia
R-Pharm International, LLC
IQVIA RDS Ireland Ltd; Thermo Fisher Scientific FS

Completed

Study in Subjects With Rheumatoid Arthritis to Evaluate the Effect of a Single Dose of Olokizumab on the Pharmacokinetics of Substrates for CYP1A2, CYP2C9, CYP2C19 and CYP3A4

Rheumatoid Arthritis

Bulgaria, Moldova, Republic of
Pfizer

Completed

STUDY TO EVALUATE THE EFFECT OF PF-06882961 ON SINGLE DOSE ATORVASTATIN, MEDAZOLAM AND ORALCONTRACEPTIVE PHARMACOKINETICS IN HEALTHY ADULT PARTICIPANTS

Healthy Adults

United States
National Institute of Allergy and Infectious Diseases...

Completed

Drug Interactions of Amprenavir and Efavirenz, in Combination With a Second Protease Inhibitor, in HIV-Negative Volunteers

HIV Infections

United States
Janssen Research & Development, LLC

Withdrawn

Study in Women on the Effect of JNJ-64530440 on Oral Contraceptive and Midazolam, and the Effect of a High-fat Meal on JNJ-64530440

Healthy

United States
Istanbul University

Completed

Single Dose of Etomidate and Adrenal Cortex

Hemodynamic Instability | Adrenocortical Deficiency

Turkey
National Institutes of Health Clinical Center (CC)

Completed

Antiretroviral Therapy for Advanced HIV Disease in South Africa

HIV

South Africa
University of Parma

Completed

Ultrasound-Guided Axillary or Infraclavicular Nerve Block for Upper Limb Surgery

Trauma | Forearm Injuries | Orthopedic Surgery | Nerve Block | Upper Extremity

Italy
National Institute of Allergy and Infectious Diseases...

Completed

Drug Interactions Among Anti-HIV Agents

HIV Infection

United States
University Hospital, Geneva

Unknown

Drug Metabolism and Antidepressant (METADEP)

Depression

Switzerland
AstraZeneca

Completed

Study to Assess the Effect of Co-Administration of AZD9833 on the Pharmacokinetics of Midazolam, of Omeprazole, of Celecoxib and of Dabigatran Etexilate in Healthy Postmenopausal Female Volunteers

Healthy Volunteers

United States
Pardes Biosciences, Inc.

Completed

Study of PBI-0451 in Healthy Subjects.

Covid19

New Zealand
Washington University School of Medicine

Completed

PECS Block vs. Multimodal Analgesia for Prevention of Persistent Postoperative Pain in Breast Surgery

Breast Cancer | Breast Cancer Female | Cancer of Breast

United States
Cairo University

Unknown

Lidocaine as an Adjuvant for Ketamine in Induction of Anesthesia in Septic Shock Patients

Septic Shock | Anesthesia

Egypt
Abbott

Completed

A Simplified Kaletra® (Lopinavir/Ritonavir)-Based Therapy Versus a Sustiva® (Efavirenz)-Based Standard of Care in Previously Non-Treated HIV-Infected Subjects

HIV Infections

United States
Jules Desmeules

Completed

Cocktail Approach for Cytochrome P450 and P-glycoprotein Activity Assessment Using Dried Blood Spot

Healthy Volunteers

Switzerland
Global Alliance for TB Drug Development

Completed

A Phase 1, Drug-Drug Interaction Study of TBAJ-876 in Healthy Adults

Tuberculosis | Tuberculosis, Pulmonary | Pulmonary Disease | Multi Drug Resistant Tuberculosis | Drug Sensitive Tuberculosis | Drug-resistant Tuberculosis | Mycobacterium Tuberculosis Infection

United States
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Blood Levels of Anti-HIV Drugs Used in Combination Regimens in HIV Infected Children

HIV Infections

United States, Puerto Rico
Montefiore Medical Center
M.D. Anderson Cancer Center; The University of Texas Health Science Center,...

Withdrawn

Preoxygenation With Optiflow™ in Morbidly Obese Patients is Superior to Face Mask

Obesity, Morbid
Janssen Research & Development, LLC

Completed

Pharmacokinetic Study to Evaluate the Effect of a Single Dose of Guselkumab (CNTO 1959) on CYP 450 Enzyme Activities After Subcutaneous Administration in Participants With Psoriasis

Psoriasis

United States
Universidade Estadual Paulista Júlio de Mesquita...
University of Sao Paulo

Completed

Influence of Age, Sepsis and SLCO1A2 Polymorphisms on Rocuronium Pharmacokinetics (ROCSEPSIS)

Sepsis | Systemic Inflammatory Response Syndrome | Septic Shock

Brazil
H. Lundbeck A/S

Completed

Drug Drug Interaction Study With Lu AG06466 in Young Healthy Men

Healthy

United States
Regeneron Pharmaceuticals
Sanofi

Completed

Open Label, Drug-Drug Interaction (DDI) Study of Dupilumab (REGN668/SAR231893) in Patients With Moderate to Severe Atopic Dermatitis (AD)

Atopic Dermatitis

United States
National Institute of Allergy and Infectious Diseases...

Completed

Increasing HAART-Induced Immune Restoration With Cyclosporine

HIV Infections

United States
Eli Lilly and Company

Completed

A Drug Interaction Study of LY3871801 in Healthy Participants

Healthy

United States
AbbVie
Boehringer Ingelheim

Completed

This Study Tests the Effect of Risankizumab on the Metabolism in the Liver of Five Additional Drugs to Study Possible Drug Interactions in Patients With Psoriasis With or Without Psoriatic Arthritis

Psoriasis

Germany
Boehringer Ingelheim

Recruiting

A Study to Compare How Different Substances (Caffeine, Warfarin, Omeprazole, Metoprolol, and Midazolam) Are Handled by the Body of Healthy People and People With Liver Cirrhosis

Liver Cirrhosis

Germany
Oregon Health and Science University

Completed

Evaluation of Oral Midazolam in First-trimester Surgical Abortions

Pain | Nausea | Anxiety

United States
Mayo Clinic

Recruiting

Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors (PNeoVCA)

Metastatic Renal Cell Carcinoma | Anatomic Stage III Breast Cancer AJCC v8 | Anatomic Stage IIIA Breast Cancer AJCC v8 | Anatomic Stage IIIB Breast Cancer AJCC v8 | Anatomic Stage IIIC Breast Cancer AJCC v8 | Prognostic Stage III Breast Cancer AJCC v8 | Prognostic Stage IIIA Breast Cancer AJCC v8 and other conditions

United States
Celgene

Completed

A Study to Evaluate the Effect of Multiple Doses of CC-90001 on the Pharmacokinetics of Omeprazole, Midazolam, Warfarin, Rosuvastatin, Metformin, Digoxin, and Nintedanib in Healthy Adult Subjects

Heathy Volunteer

United States
Janssen Sciences Ireland UC

Completed

A Study in Healthy Female Participants to Investigate the Effect of JNJ-56136379 at Steady-state on the Single-dose Pharmacokinetics of Ethinylestradiol and Drospirenone (Oral Contraceptive) and on the Single-dose Pharmacokinetics of Midazolam (Probe Substrate for Cytochrome P450 3A4)

Healthy

Belgium
National Institute of Allergy and Infectious Diseases...

Completed

A Study to Compare The Ability of Different Anti-HIV Drugs to Decrease Viral Load After Nelfinavir (an Anti-HIV Drug)Treatment Failure

HIV Infections

United States, Puerto Rico
Mirati Therapeutics Inc.

Completed

PK Study to Assess Drug-drug Interaction and QTc Between Sitravatinib and a Cocktail of Substrates

Advanced Solid Tumor

United States
Hospital for Special Surgery, New York

Completed

The Combination of Adductor Canal Block and Periarticular Injection. A Novel Technique for Patients Undergoing Total Knee Replacement (ACB PAI) (ACB PAI)

Osteoarthritis

United States
University of Florida
National Institutes of Health (NIH); National Institute of General Medical...

Completed

Project 4B: Lower Extremity Strength Training in ICU Patients

Sepsis

United States
Matthias Schwab

Completed

Open Label Study for the Functional Characterization of Drug Metabolism and Transport (IKP243)

Genotype-related Drug Metabolism

Germany
CES University
Hospital Pablo Tobón Uribe; Clinica CES

Unknown

Comparison of Two Techniques of Sciatic Nerve Block With Levobupivacaine 0.5% in Orthopedic Surgery

Anesthesia

Colombia
Harvard School of Public Health (HSPH)
Bristol-Myers Squibb; McGill University Health Centre/Research Institute of... and other collaborators

Completed

The Adult Antiretroviral Treatment and Resistance Study (Tshepo)

HIV Infection | AIDS

Botswana
Federal University of São Paulo
Faculdade de Ciências Médicas da Santa Casa de São Paulo

Unknown

Laparoscopic Cholecystectomy: General Anesthesia With Opioid Versus General Opioid Free Anesthesia (GALOFF)

Pain, Postoperative | Nausea | Vomiting | Hemodynamic Instability | Anesthesia Complication | Ileus Paralytic

Brazil
Merck Sharp & Dohme LLC

Completed

A Single-Dose Study to Investigate the Pharmacokinetics of MK-7655 in Participants With Impaired Renal Function (MK-7655-005)

Infectious Disease
Nationwide Children's Hospital

Completed

Analgesic Effect of IV Acetaminophen in Tonsillectomies

Tonsillitis | Adenotonsillitis

United States

3

Subscribe