Search clinical trials for: SACT-1

Total 15892 results

Idorsia Pharmaceuticals Ltd.

Completed

A Study to Investigate the Safety, Tolerability, Pharmacokinetics (PK), and Pharmacodynamics (PD) of ACT-541468 in Healthy Young Adults and Elderly Subjects

Healthy Subjects

Netherlands
Aptorum International Limited

Completed

A Study of Bioavailability and Food Effect of SACT-1 and Edurant® Tablets in Healthy Adult Volunteers

Healthy Subject

United States
University of Oxford

Completed

Study to Compare the Triple ACT AL+AQ With the ACT AL in Cambodia and Vietnam (TACT-CV)

Malaria, Falciparum

Cambodia, Vietnam
VA Office of Research and Development
VA Connecticut Healthcare System; North Texas Veterans Healthcare System

Not yet recruiting

Assessing the Efficacy of an Acceptance-Based Digital Intervention for Veterans With Chronic Pain (VACT-CP)

Chronic Pain

United States
Sinocelltech Ltd.

Unknown

Safety and Efficacy of SCT-I10A in Head and Neck Squamous Cell Carcinoma

Head and Neck Squamous Cell Carcinoma

China
M.D. Anderson Cancer Center
MDS Clinical Research Consortium

Completed

Interventional Validation of an MDS-Specific Measure of Quality of Life: Assessing the Responsiveness of the Quality of Life in Myelodysplasia Scale (QUALMS-1) to Different Hypomethylating Agent Regimens for Low and Intermediate Risk Disease

Leukemia

United States
University of Oxford

Completed

A Study by the Tracking Resistance to Artemisinin Collaboration (TRAC) (TRACII)

Malaria, Falciparum

Bangladesh, Cambodia, Congo, The Democratic Republic of the, India, Lao People's Democratic Republic, Myanmar, Thailand, Vietnam
Seoul National University Hospital

Completed

Locoregional Recurrence After Neoadjuvant Versus Adjuvant Chemotherapy

Breast Cancer

Korea, Republic of
Peking University

Unknown

Real World Evidence for the Cycle of Neoadjuvant Chemotherapy in Gastric Cancer With Shared Decision Making (RECOMMEND)

Gastric Cancer

China
Idorsia Pharmaceuticals Ltd.

Completed

A Study to Assess the Tolerability, Safety, Pharmacodynamics, and Pharmacokinetics of Ascending Single Doses (Including Food Interaction) and Ascending Multiple Doses of ACT-453859, and Multiple Doses of Setipiprant (ACT-129968)

Healthy
Idorsia Pharmaceuticals Ltd.

Completed

Study to Investigate the Tolerability, Safety, Pharmacokinetics, and Pharmacodynamics of ACT-389949

Healthy Subjects

Netherlands
NovaBay Pharmaceuticals, Inc.
Novum Pharmaceutical Research Services; International Dermatology Research,...

Completed

Safety and Efficacy of Topical NVC-422 Gel in Impetigo

Impetigo

Dominican Republic
Peking University
Beijing Municipal Science & Technology Commission

Unknown

A Comparison of Laparoscopic With Open Distal Gastrectomy in Advanced Gastric Cancer After Neoadjuvant Chemotherapy (REALIZATION)

Gastric Cancer

China
Société des Produits Nestlé (SPN)

Completed

Iron Bioavailability From Dairy Product

Healthy Volunteers

Switzerland
Actelion

Completed

Clinical Study to Evaluate the Efficacy, Safety, and Tolerability of ACT-128800 in Patients With Relapsing-remitting Multiple Sclerosis

Multiple Sclerosis

United States, Australia, Austria, Belgium, Bulgaria, Canada, Czechia, Finland, France, Germany, Hungary, Israel, Italy, Netherlands, Poland, Romania, Russian Federation, Serbia, Spain, Sweden, Switzerland, Ukraine, United Kingdom
Duke University
National Institute of Allergy and Infectious Diseases (NIAID); Moi University; Clinton Health Access Initiative, Nigeria

Completed

Malaria Diagnostic Testing and Conditional Subsidies to Target ACTs in the Retail Sector: the TESTsmART Trial AIM 1 (TESTsmART)

Malaria | Febrile Illness

Kenya
Lesaffre International
BioFortis; Soladis

Terminated

Bioavailability Study of Folate in Healthy Subjects

Healthy

France
Mind Mental Health Hong Kong Limited
Chinese University of Hong Kong

Recruiting

Evaluation of Training Curriculum and Service of Improving Access to Community Therapies (iACT)

Depression | Stress | Anxiety | Distress, Emotional | Mental Health Issue

China
Johns Hopkins University
University of South Carolina

Completed

Stimulating Language in Subacute StrokE (SLISSE)

Stroke

United States
NYU Langone Health

Not yet recruiting

Potassium Containing Salt-Substitute in Hemodialysis-Dependent End Stage Kidney Disease

End Stage Kidney Disease

United States
Shu-Zhong Cui
Xiangya Hospital of Central South University; Wuhan University; Peking University... and other collaborators

Unknown

Efficacy of HIPEC as NACT and Postoperative Chemotherapy in the Treatment of Advanced-Stage Epithelial Ovarian Cancer (EHNPCTASEOC)

Fallopian Tube Cancer | Epithelial Ovarian Cancer | Primary Peritoneal Carcinoma

China
University of Delaware

Completed

The Salty Gut: Effects of High Dietary Salt Intake on the Gut Microbiota

Cardiovascular Risk Factor

United States
Northwestern University
National Institute on Aging (NIA)

Completed

The Effect of Fact Versus Myth Messages on Receipt of Influenza Vaccination

Influenza Vaccination

United States
Idorsia Pharmaceuticals Ltd.

Completed

Clazosentan in Preventing the Occurrence of Cerebral Vasospasm Following an Aneurysmal Subarachnoid Hemorrhage (aSAH) (CONSCIOUS-1)

Aneurysmal Subarachnoid Hemorrhage

United States, Canada
University of Southern Denmark
Odense University Hospital; Beckett Foundation; Danish Diabetes Academy

Completed

The Influence of High and Low Salt on Exosomes in the Urine

Healthy

Denmark
University College, London
Cancer Research UK

Unknown

Stereotactic Ablative Radiotherapy for Oligometastatic Non-small Cell Lung Cancer (SARON)

Non-small Cell Lung Cancer

United Kingdom
Linnaeus University
Kronoberg County Council; Capio Group

Completed

PCBH With the Addition of Self-help CBT

Quality of Life | Stress | Insomnia | Psychological Distress | Depression, Anxiety | Activities, Daily Living

Sweden
Vanderbilt University

Completed

The Natriuretic Peptide System in African-Americans.

Healthy | Prehypertension

United States
Istituto Auxologico Italiano

Recruiting

ACTyourCHANGE Study Protocol. Promoting Healthy Lifestyle With ACT for Obesity (ACTyourCHANGE)

Health Behavior

Italy
University College Cork

Completed

'Low-salt' Bread as a Means of Reducing Dietary Salt and Lowering Blood Pressure (Saltbreads)

Elevated Blood Pressure

Ireland
VA Office of Research and Development

Completed

PACT for Individuals With Serious Mental Illness (SMI-PACT)

Schizophrenia Spectrum & Other Psychotic Disorders

United States
Barts & The London NHS Trust
St. Bartholomew's Hospital

Completed

A Bengali Dietary Salt Study to Control Blood Pressure

Hypertension

United Kingdom
Academia Sinica, Taiwan

Completed

The Effect of Intervention With Potassium and/ or Magnesium-enriched Salt on Neurological Performance of Stroke Patients

Stroke
Oxford Brookes University

Completed

Salt Intake, Hydration Status and Gastrointestinal Discomfort During Fasting

Healthy

United Kingdom
Mulungushi University

Recruiting

Immediate Pressor Response to Oral Salt (IPROS)

High Blood Pressure

Zambia
Estudios Clínicos Latino América
Population Health Research Institute

Recruiting

The ECLA/PHRI Intervention in the Community Trial (EPIC)

Hypertension

Argentina
Peking University
Health Science Center of Xi'an Jiaotong University; Changzhi Medical College; Hohhot Center for Disease Control and Prevention and other collaborators

Completed

Diet, ExerCIse and carDiovascular hEalth (DECIDE) - Salt Reduction Strategies for the Elderly in Nursing Homes in China (DECIDE-Salt)

Blood Pressure

China
Brigham and Women's Hospital

Terminated

Salt and TH-17 in Healthy Human Subjects

Autoimmunity | Sodium Chloride | Salt Intake | Th17 Helper Immune Cells

United States
University of California, San Francisco
University of Colorado, Denver; University of California, Davis; Post Graduate...

Completed

Study of Multiply-fortified Salt Among Women of Reproductive Age and Preschool Children in India (MFS)

Nutrient Deficiency

India
Vanderbilt University Medical Center

Completed

Visualizing Vascular Mechanisms of Salt Sensitivity

Obesity | Cardiovascular Risk Factor | Salt; Excess

United States
ResMed

Completed

Performance of the Salt Lake Mask System

Obstructive Sleep Apnea

Australia
University of Michigan
Renal Research Institute

Completed

Lowering Salt Intake in Chronic Kidney Disease: A Pilot Randomized Crossover Trial (BIA)

Kidney Disease

United States
Bellicum Pharmaceuticals

Active, not recruiting

Safety Study of Gene Modified Donor T-cells Following Partially Mismatched Stem Cell Transplant

Lymphoma | Myelodysplastic Syndromes | Acute Lymphoblastic Leukemia | Acute Myelogenous Leukemia

United States
University of Kiel

Completed

Endogenous vs. Exogenous Ketone Bodies

Healthy

Germany
Yonsei University

Terminated

Impact of Balanced Slat Colloid HES 130/0.42 on Coagulation Profiles in Patients Undergoing Spinal Cord Tumor Surgery

Coagulation

Korea, Republic of
Aga Khan University
Wellcome Trust

Unknown

Effects of Low Salt Diet Versus High Salt Diet on Blood Pressure

Hypertension

Pakistan
Hospital Clínico Universitario de Valladolid

Unknown

Salt Intake, Microbiota, Immune Response and Endothelial Function in Hypertension

Hypertension

Spain
University of Southern Denmark
Central Denmark Region; Region Capital Denmark; Region of Southern Denmark; Copenhagen... and other collaborators

Recruiting

Paediatric Autism Communication Therapy (PACT) in Children With Autism Spectrum Disorder (DAN-PACT)

Autism Spectrum Disorder

Denmark
Universidad Peruana Cayetano Heredia
Johns Hopkins University

Completed

Launching a Salt Substitute to Reduce Blood Pressure at the Population Level in Peru

Hypertension | Blood Pressure

Peru
Mulungushi University
University of Zambia

Completed

Acute Salt Sensitivity of Blood Pressure (AcuteSS)

Blood Pressure

Zambia

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