Search clinical trials for: SAGE-718-matching placebo

Total 1535 results

Zogenix, Inc.

Completed

A Multicenter Active Comparator Study of HC-ER in Adults Following Bunionectomy Surgery

Postoperative Pain
AstraZeneca

Completed

A Placebo-controlled Four Way Crossover Study to Asses the Effect of a Single Oral Dose of NKTR-118 on QTc Interval in Healthy Male Subjects

Amount of NKTR-118 in Blood | Variation in the Heart's Electrical Cycle

United States
AbbVie (prior sponsor, Abbott)

Completed

Study to Evaluate the Safety and Efficacy of ABT-712 in Subjects With Moderate to Severe Chronic Low Back Pain (CLBP)

Chronic Low Back Pain

United States
Abbott

Completed

A Study of Pain Relief in Osteoarthritis

Osteoarthritis

United States
Grünenthal GmbH
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.

Terminated

A Study to Evaluate the Effectiveness and Safety of CG5503 (Tapentadol) in the Treatment of Chronic Tumor Related Pain Compared With Placebo and Morphine

Pain | Cancer | Neoplasm

United States, Argentina, Chile, France, Latvia, Ukraine
Purdue Pharma LP

Completed

The Effect of Buprenorphine Delivered by Buprenorphine Transdermal System (BTDS) on QT Intervals in Healthy Volunteers

Healthy Volunteers

United States
Anhui Palo Alto Pharmaceuticals, Inc.

Completed

Safety, Tolerability, and Pharmacokinetics of PA9159 Nasal Spray in Healthy Adult Subjects

Allergic Rhinitis

China
University of L'Aquila

Completed

Effect of Single Rinsing With Three Different Types of Mouthwash on VSC Levels in Morning Breath

Halitosis

Italy
Eli Lilly and Company

Completed

A Study of the Effect of LY2189265 on Two Blood Pressure Drugs

Diabetes Mellitus, Type 2

United States
Medical University of Vienna

Completed

The Role of the P2Y12 Receptor in Tissue Factor Induced Coagulation

Sepsis | Healthy Volunteers

Austria
AbbVie (prior sponsor, Abbott)

Completed

Study to Evaluate the Safety and Efficacy of ABT-712 in Subjects With Moderate to Severe Chronic Low Back Pain (CLBP)

Chronic Low Back Pain

United States
AbbVie (prior sponsor, Abbott)

Completed

Phase 2 Chronic Low Back Pain Study

Chronic Low Back Pain

United States
Boehringer Ingelheim

Completed

A Study in Healthy Men to Test How Well Multiple Doses of BI 1839100 Are Tolerated and How BI 1839100 Influences the Amount of Other Medicines in the Blood

Healthy

Netherlands
Naga P. Chalasani
DSM Nutritional Products, Inc.

Completed

Vitamin E and DHA-EE on NAFLD - Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Clinical Trial (PUVENAFLD) (PUVENAFLD)

Non-Alcoholic Fatty Liver Disease | Non-Alcoholic Steatohepatitis | Non-Alcoholic Fatty Liver

United States
Sansum Diabetes Research Institute

Withdrawn

Role of Pregnancy Related Hormones in Lowering the Insulin Requirement in Pregnant Women With Type 1 Diabetes

Type 1 Diabetes

United States
Kaohsiung Veterans General Hospital.

Completed

Efficacy of H2 Receptor Antagonist in Prevention of Thienopyridine-related Peptic Ulcer

Peptic Ulcer

Taiwan
Fred Lublin
National Institute of Neurological Disorders and Stroke (NINDS)

Completed

Combination Therapy in Patients With Relapsing-Remitting Multiple Sclerosis (MS)CombiRx

Relapsing Remitting Multiple Sclerosis

United States, Canada
Boehringer Ingelheim

Completed

Pharmacodynamic and Pharmacokinetic Dose Ranging Study of Tiotropium Bromide Administered Via Respimat Device in Patients With Chronic Obstructive Pulmonary Disease (COPD)

Pulmonary Disease, Chronic Obstructive
Novartis

Completed

26 Week Efficacy, Safety and Tolerability Study of Indacaterol in Patients With Chronic Obstructive Pulmonary Disease (COPD)

Lung Diseases, Obstructive | Pulmonary Disease, Chronic Obstructive | COPD

United States, Germany, Spain, Argentina, Italy, Turkey, Canada, India, Sweden, Korea, Republic of, Taiwan, Puerto Rico
Abbott

Completed

A Study Comparing the Analgesic Activity of Extended Release Hydrocodone/Acetaminophen (Vicodin® CR) and Placebo in Subjects With Pain Following Bunionectomy Surgery

Pain

United States
Shire

Completed

Ciprofloxacin XR Drug Interaction Study With MMX® Mesalazine/Mesalamine

Healthy

United States
Gilead Sciences

Completed

Safety, Tolerability, Pharmacokinetics and Antiviral Activity of GS-9669 in Subjects With Chronic Hepatitis C Virus Infection

Hepatitis C

United States, Puerto Rico
Pearl Therapeutics, Inc.

Completed

Study to Assess the Efficacy and Safety of PT003, PT005, and PT001 in Subjects With Moderate to Very Severe COPD

Chronic Obstructive Pulmonary Disease

United States, Germany, United Kingdom, China, Taiwan, Korea, Republic of, Japan, Czechia, Hungary, Poland, Russian Federation
Novartis Pharmaceuticals

Completed

Comparison of the Effects of Indacaterol and Tiotropium on Inspiratory Capacity

Chronic Obstructive Pulmonary Disease

Italy
Novartis Pharmaceuticals

Completed

Efficacy and Safety of Indacaterol Plus Tiotropium Versus Tiotropium Alone in Patients With Chronic Obstructive Pulmonary Disease (INTRUST2)

Chronic Obstructive Pulmonary Disease (COPD)

United States, Colombia, Spain, Canada, Slovakia, India, Netherlands, Czech Republic, Hungary
AbbVie (prior sponsor, Abbott)

Completed

Acute Pain Study Following Bunionectomy

Pain

United States
Duke University
Shire

Completed

Attention Deficit Hyperactivity Disorder (ADHD) Smoking Cessation Study

Attention Deficit Hyperactivity Disorder | Nicotine Dependence

United States
Teva Branded Pharmaceutical Products R&D, Inc.

Withdrawn

A Study of 3 Doses of Tiotropium Hydrofluoralkane (HFA) Breath Actuated Inhaler (BAI), in Patients With Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease | COPD
Novartis Pharmaceuticals

Completed

Efficacy and Safety of Indacaterol Plus Tiotropium Versus Tiotropium Alone in Patients With Chronic Obstructive Pulmonary Disease (INTRUST1)

Chronic Obstructive Pulmonary Disease (COPD)

United States, Colombia, Argentina, Germany, Spain, Turkey, Guatemala, Mexico, Australia, Denmark, South Africa, Philippines
Cedars-Sinai Medical Center

Withdrawn

Oral Clonidine & Gabapentin: Improving Recovery and Pain Management After Outpatient With Major Orthopedic Surgery

Knee Arthroscopy | Shoulder Arthroscopy

United States
AstraZeneca

Completed

Efficacy of Aclidinium Bromide Administered in Chronic Obstructive Pulmonary Disease (COPD) Patients

Chronic Obstructive Pulmonary Disease (COPD)

Germany
AbbVie (prior sponsor, Abbott)

Completed

Hydrocodone/Acetaminophen for Acute Pain Following Bunionectomy

Pain

United States
Abbott

Completed

A Study Comparing the Analgesic Efficacy and Safety of Extended Release Hydrocodone/Acetaminophen (Vicodin® CR)and Placebo in Subjects With Osteoarthritis

Pain
SWOG Cancer Research Network
National Cancer Institute (NCI)

Completed

S1001 PET-Directed Therapy in Treating Patients With Limited-Stage Diffuse Large B-Cell Lymphoma

Lymphoma

United States
University Hospital, Rouen
Federation Francophone de Cancerologie Digestive

Recruiting

Study on Aspirin Versus Placebo in Resected Colon Cancer With PI3K Mutation Stage III or II High Risk (ASPIK French)

Colorectal Cancer

France
Chiesi Farmaceutici S.p.A.

Completed

A 6-week Dose Ranging Study of CHF 5259 pMDI in Subjects With Chronic Obstructive Pulmonary Disease (GLIMMER)

Chronic Obstructive Pulmonary Disease | COPD

United States
Idorsia Pharmaceuticals Ltd.

Completed

To Study the Effect of Cenerimod on the Electrical Activity of the Heart, in Men and Women. To Study the Effect of Cenerimod on the Use of Oral Contraceptives in Women. To Study the Effect That Charcoal Has on the Elimination of Cenerimod From the Body, in Women and Men.

Healthy Subjects

France
Merck Sharp & Dohme LLC

Completed

Study of MK-1029 in Participants With Persistent Asthma That Cannot Be Controlled With Montelukast (MK-1029-015)

Asthma
AO GENERIUM

Withdrawn

Efficacy and Safety of GNR-038 vs Berinert® in Patients With Hereditary Angioedema

Hereditary Angioedema

Russian Federation
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI); Novartis Pharmaceuticals

Active, not recruiting

Daunorubicin, Cytarabine, and Midostaurin in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia

Leukemia

United States, Canada
Center for Neurologic Study, La Jolla, California,
State University of New York - Upstate Medical University; ALS Association

Completed

Clinical Trial Nuedexta in Subjects With ALS

Amyotrophic Lateral Sclerosis (ALS)

United States
Harvard School of Public Health (HSPH)
Harvard Medical School (HMS and HSDM); National Institute of Allergy and Infectious... and other collaborators

Completed

Study to Improve Survival Among HIV-Exposed Infants in Botswana (Mpepu)

HIV Infections | Anemia | Neutropenia

Botswana
CES University
Hospital Pablo Tobón Uribe; Clinica CES

Unknown

Comparison of Two Techniques of Sciatic Nerve Block With Levobupivacaine 0.5% in Orthopedic Surgery

Anesthesia

Colombia
Abbott

Completed

A Study of Extended-Release Hydrocodone/Acetaminophen (Vicodin CR®) in Subjects With Acute Pain Following Bunionectomy

Pain

United States
Hill Dermaceuticals, Inc.

Recruiting

Phase III Efficacy and Safety Study of Miconazole Oil for Otomycosis

Otomycosis

United States
Phargentis SA

Completed

Bioequivalence Study of Tiotropium Bromide Inhalation Powder

COPD

United States, India, Switzerland
Bispebjerg Hospital
Lund University; The Danish Rheumatism Association; Ministry of the Interior...

Unknown

Effect of Glucosamine or Ibuprofen Combined With Physical Training in Patients With Knee-Osteoarthritis

Osteoarthritis of the Knee
Biogen

Recruiting

A Study to Assess Pregnancy Outcomes in Women Exposed to Diroximel Fumarate

Multiple Sclerosis

United States
AbbVie (prior sponsor, Abbott)

Completed

Hydrocodone/Acetaminophen for Acute Pain Following Third Molar Tooth Extraction

Pain

United States
AbbVie (prior sponsor, Abbott)

Terminated

A Study Comparing the Efficacy and Safety of ABT-652 to Placebo in Subjects With Diabetic Neuropathic Pain

Diabetic Neuropathic Pain

United States

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