Search clinical trials for: SHR3824, Simvastatin

Total 618 results

Jiangsu HengRui Medicine Co., Ltd.

Unknown

Drug-drug Interaction Between Simvastatin and SHR3824

Type 2 Diabetes
Jiangsu HengRui Medicine Co., Ltd.

Unknown

Safety and Pharmacokinetics/Pharmacodynamics of SHR3824 in Patients With Hepatic Impairment

Hepatic Impairment

China
Jiangsu HengRui Medicine Co., Ltd.

Completed

Effect of a High-fat Meal on the Pharmacokinetics of SHR3824 and Mass Balance Study in Healthy Subjects

Type 2 Diabetes
Jiangsu HengRui Medicine Co., Ltd.

Unknown

Safety and Pharmacokinetics/Pharmacodynamics of SHR3824 in Type 2 Diabetes Patients With Renal Insufficient

Renal Insufficiency,Type 2 Diabetes

China
Jiangsu HengRui Medicine Co., Ltd.

Completed

Pharmacodynamics, Pharmacokinetics, Safety and Tolerability of SHR3824 in Type 2 Diabetes Mellitus Patients

Type 2 Diabetes Mellitus
Jiangsu HengRui Medicine Co., Ltd.

Unknown

Efficacy and Safety of SHR3824 as Monotherapy in Subjects With Type 2 Diabetes

Type 2 Diabetes Mellitus

China
Jiangsu HengRui Medicine Co., Ltd.

Unknown

The PK/PD, Efficacy, Safety and Tolerability Study of SHR3824 in Type 2 Diabetes Mellitus Patients

Type 2 Diabetes Mellitus

China
Jiangsu HengRui Medicine Co., Ltd.

Completed

The PK/PD Study of Multiple Dose of SHR3824 in Healthy Volunteers

Type 2 Diabetes

China
Jiangsu HengRui Medicine Co., Ltd.

Completed

The PK/PD Study of Single Dose of SHR3824 in Healthy Volunteers (SHR3824)

Type 2 Diabetes

China
Jiangsu HengRui Medicine Co., Ltd.

Unknown

The Drug-drug Interaction of SHR3824 and SP2086

Type 2 Diabetes

China
Jiangsu HengRui Medicine Co., Ltd.

Unknown

The PK/PD, Efficacy, Safety and Tolerability Study of SHR3824 in Combination With Metformin in Type 2 Diabetes Mellitus Patients

Type 2 Diabetes Mellitus
Juan A. Arnaiz

Completed

Efficacy of Statin Association With Standard Treatment in Prevention of Recurrent Hemorrhage in Patient With Cirrhosis and Variceal Bleeding

Cirrhosis | Hypertension, Portal | Portal Vein Thrombosis | Bleeding Esophageal Varices

Spain
Tel-Aviv Sourasky Medical Center

Unknown

Simvastatin Treatment of Pachyonychia Congenita

Pachyonychia Congenita
Jiangsu HengRui Medicine Co., Ltd.

Completed

The Drug-drug Interaction of SHR3824 and Metformin

Type 2 Diabetes
Jiangsu HengRui Medicine Co., Ltd.

Unknown

Efficacy and Safety of SHR3824 in Combination With Metformin in Subjects With Type 2 Diabetes

Type 2 Diabetes Mellitus

China
University of Copenhagen

Completed

Living With Statins - The Impact of Cholesterol Lowering Drugs on Health, Lifestyle and Well-being (LIFESTAT)

Cardiovascular Disease | Diabetes Mellitus

Denmark
Vejle Hospital

Completed

The Effect of High Dose Simvastatine on Multiple Myeloma

Multiple Myeloma
Shandong Suncadia Medicine Co., Ltd.

Not yet recruiting

A Study to Assess the Bioequivalence of Fixed Dose Combination of HR20033 Relative to Co-administration of the Individual Components in Healthy Chinese Subjects

Type II Diabetes
RenJi Hospital

Not yet recruiting

The Effect of Henagliflozin and Metformin on Myocardial Tissue-level Characteristics

Myocardial Fibrosis | Obesity | Type 2 Diabetes | Magnetic Resonance Imaging | Sodium-glucose Co-transporter-2 Inhibitor
Organon and Co

Completed

IMPROVE-IT: Examining Outcomes in Subjects With Acute Coronary Syndrome: Vytorin (Ezetimibe/Simvastatin) vs Simvastatin (P04103)

Myocardial Infarction | Hypercholesterolemia
dr.Frank L.J. Visseren
Merck Sharp & Dohme LLC

Completed

The PostprAndial eNdothelial Function After Combination of Ezetimibe and simvAstatin Study (PANACEA)

Metabolic Syndrome

Netherlands, Spain
University of Sao Paulo

Completed

Effects of Statin and Ezetimibe Association on Kinetics of Artificial Chilomicrons

Coronary Heart Disease
University of Maryland, Baltimore
Merck Sharp & Dohme LLC

Completed

Simvastatin With or Without Ezetimibe and Atherothrombotic Biomarker Assessment

Metabolic Syndrome

United States
Peking Union Medical College Hospital

Unknown

Efficacy and Safety of Simvastatin-ezetimibe Combination Therapy Among Patients With SLE

Atherosclerosis

China
Hue University of Medicine and Pharmacy
Università degli Studi di Sassari

Unknown

Lipid-lowering Therapies in Vietnamese Chronic Kidney Disease Population (VietCKD)

Chronic Kidney Diseases | Hypercholesterolemia

Vietnam
Organon and Co

Completed

Effectiveness of Two Approved Drugs in Lowering High Cholesterol (0733-224)

Hypercholesterolemia
Organon and Co
Schering-Plough

Completed

The Effects of Ezetimibe/Simvastatin 10/20 mg Versus Simvastatin 40 mg in High Cholesterol and Coronary Heart Disease Study (P04039AM2)(COMPLETED)

Coronary Disease | Hypercholesterolemia
Federal State Budgetary Scientific Institution,...

Completed

Simvastatin in Uveitis

Uveitis

Russian Federation
Abbott

Completed

A 12-week Study to Compare the Efficacy and Safety of Fixed Combinations of Fenofibrate/Simvastatin 145/20mg and Fenofibrate/Simvastatin 145/40mg Tablets Versus Fenofibrate or Simvastatin Monotherapies in Subjects With Abnormal Blood Levels of Fats (Lipids) and at High Risk of Cardiovascular Disease

Dyslipidemia

Argentina, Czech Republic, Germany, Mexico, Poland, Romania, Russian Federation
Solvay Pharmaceuticals

Completed

Interaction Study SLV337/Simvastatin

Type 2 Diabetes Mellitus

United Kingdom
AstraZeneca

Completed

A Study to Assess Co-Administered AZD9056 (Steady State) and Simvastatin (Single Dose) in Healthy Volunteers

Healthy Volunteers

Germany
Organon and Co

Completed

A Study of MK0653A (Ezetimibe (+) Simvastatin) in Patients With Hypercholesterolemia (0653A-038)

Hypercholesterolemia
National Cheng-Kung University Hospital

Completed

Vascular Effects of Ezetimibe/Simvastatin and Simvastatin on Atherosclerosis

Atherosclerosis

Taiwan
Helsinki University Central Hospital
University of Helsinki; Academy of Finland

Completed

Donor Simvastatin Treatment in Organ Transplantation (SIMVA)

Liver Failure | Heart Failure | Respiratory Failure | Kidney Failure | Transplantation

Finland
University of Copenhagen

Unknown

Living With Statins - Interventional Exercise Study (LIFESTAT)

Cardiovascular Disease | Diabetes Mellitus

Denmark
Azienda Ospedaliero Universitaria di Sassari

Unknown

Ezetimibe/Simvastatin Combination in Proteinuric Nephropathy (VICTORY)

Hypercholesterolemia | Chronic Nephropathy

Italy
Organon and Co

Completed

To Evaluate Ezetimibe/Simvastatin and Niacin (Extended Release Tablet) in Patients With Type IIa or Type IIb Hyperlipidemia (0653A-091)(COMPLETED)

Hypercholesterolemia
Organon and Co
Merck Sharp & Dohme LLC

Completed

Effects of Ezetimibe With Simvastatin in the Therapy of Adolescents With HeFH (Study P02579)

Hypercholesterolemia
Brasilia Heart Study Group

Completed

Effect of Statin Treatment on Insulin Sensitivity During Myocardial Infarction

Myocardial Infarction

Brazil
Charite University, Berlin, Germany
German Federal Ministry of Education and Research

Unknown

Trial of Simvastatin in Amnestic Mild Cognitive Impairment (MCI) Patients (SIMaMCI)

Mild Cognitive Impairment

Germany
University of Cologne
Merck Sharp & Dohme LLC

Completed

LDL Receptor Under Ezetimibe and Simvastatin

Healthy Men

Germany
Judit Pich

Completed

Simvastatin Plus Rifaximin in Decompensated Cirrhosis (LIVERHOPE)

Cirrhoses, Liver

Spain, Germany, United Kingdom, Italy, Netherlands, France
Organon and Co
Merck Sharp & Dohme LLC; Schering-Plough

Completed

Effects of Vytorin Versus Placebo in Subjects With Primary Hypercholesterolemia (Study P04420)

Hypercholesterolemia
Centre hospitalier de l'Université de Montréal...
Centre de Recherche du Centre Hospitalier de l'Université de Montréal

Terminated

Efficacy Study of SIMVASTATIN to Treat Chronic Rhinosinusitis After Failure of Optimal Treatment

Rhinosinusitis

Canada
University of Sao Paulo

Completed

Antiplatelet and Anti-inflammatory Effects of Statins and Ezetimibe

Stable Angina

Brazil
Heidelberg University

Completed

Effects on NF-κB Activity: High Dose Simvastatin Versus Combination Therapy With Ezetimibe

Inflammation | Type 2 Diabetes

Germany
Gachon University Gil Medical Center

Completed

Vascular and Metabolic Effects of Vytorin vs Simvastatin

Hypercholesterolemia

Korea, Republic of
Federal University of Bahia
Escola Bahiana de Medicina e Saude Publica

Unknown

Pleiotropism of Statin Therapy in High Dose Versus Low Dose Combined With Ezetimibe

Endothelial Function

Brazil
UMC Utrecht

Completed

Effects of Ezetimibe on Postprandial Hyperlipidemia and Endothelial Function

Metabolic Syndrome

Netherlands
University of Ioannina

Completed

Comparison of Simvastatin Versus Simvastatin/Ezetimibe on Small Dense Low -Density Lipoprotein (LDL)

Hypercholesterolemia

Greece

3

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