Search clinical trials for: SPL-108

Total 5485 results

University of North Carolina, Chapel Hill
Johns Hopkins University; Novartis Pharmaceuticals

Completed

Durability of Hypertonic Saline for Enhancing Mucociliary Clearance in Cystic Fibrosis

Cystic Fibrosis

United States
Pfizer

Completed

Long-Term Open-Label Extension Trial for Subjects Completing the Phase 3 Trial of Fesoterodine (SP584) for the Treatment of Overactive Bladder Syndrome

Overactive Bladder Syndrome

United States
Pfizer

Completed

Trial to Investigate the Efficacy, Tolerability and Safety of Fesoterodine Sustained Release in Subjects With Overactive Bladder Syndrome

Overactive Bladder
Axon Neuroscience SE

Completed

18-months Safety Follow-up Study of AADvac1, an Active Tau Vaccine for Alzheimer's Disease (FUNDAMANT)

Alzheimer's Disease

Austria
University of North Carolina, Chapel Hill
Patient-Centered Outcomes Research Institute; Children's Hospital of Philadelphia and other collaborators

Recruiting

A Comparison of Two Brief Suicide Prevention Interventions Tailored for Youth on the Autism Spectrum

Suicidal Ideation | Suicide | Autism Spectrum Disorder | Suicidal and Self-injurious Behavior

United States
He Eye Hospital

Not yet recruiting

Comparison of Non-pharmaceutical Treatments for Evaporative Dry Eye

Dry Eye
GlaxoSmithKline
Optum-data vendor

Completed

Chronic Obstructive Pulmonary Disease (COPD) Dual Therapy Burden of Illness

Pulmonary Disease, Chronic Obstructive

United States
Zealand University Hospital

Unknown

Treatment of Axillary Hyperhidrosis With Long-pulsed Nd:YAG Laser or IPL

Hyperhidrosis Primary Focal Axilla

Denmark
European Association for Endoscopic Surgery

Completed

Multi-Port Versus Single-port Cholecystectomy (MUSIC)

Cholelithiasis

Italy
Le Syndicat Intercommunal pour le Thermalisme et...
Floralis

Completed

Assessment of the Effect of Spa Treatment on the Functional Severity of Arthrosis (VALS)

Pain | Osteoarthritis, Knee

France
Lumenis Be Ltd.

Terminated

Impact of the M22-IPL Acne Filter on Acne Vulgaris

Acne

United States
Supernus Pharmaceuticals, Inc.

Completed

Phase I Study to Assess the Absorption, Metabolism, and Excretion of [14C] Labeled SPN-810M

Impulsive Aggression Comorbid With ADHD

United Kingdom
Centre Jean Perrin

Terminated

Support and Rehabilitation Protocol for Non Metastatic Breast Cancer Patients in Complete Remission After Chemotherapy

Non Metastatic Breast Cancer

France
Pfizer

Completed

Two Phase Extension Trial of SP668 to Investigate the Safety and Tolerability of Sustained Release Fesoterodine in Subjects With Overactive Bladder: a Double-Blind Phase Followed by an Open-Label Extension Phase

Overactive Bladder

United States
Jiangsu Yahong Meditech Co., Ltd aka Asieris

Recruiting

A Study to Evaluate the Safety and Efficacy of Oral APL-1202 in Combination With Tislelizumab Compared to Tislelizumab Alone as Neoadjuvant Therapy in Patients With Muscle Invasive Bladder Cancer (ANTICIPATE)

Muscle Invasive Bladder Cancer

United States, China
Fundació d'investigació Sanitària de les Illes...
Hospital Son Espases

Recruiting

Clinical Trial to Estimate the Efficacy of the Trapezium-Metacarpal (TMC) Prosthesis Compared to Suspensionplasty.

First CarpoMetacarpal Osteoartrithis | Basal Thumb Osteoartrithis

Spain
San Diego State University
National Institute of Mental Health (NIMH)

Completed

Suicide Prevention for Sexual and Gender Minority Youth (Open Trial)

Suicide

United States
Apellis Pharmaceuticals, Inc.

Completed

A Study of APL-9 in Adults With Mild to Moderate ARDS Due to COVID-19

Severe Acute Respiratory Syndrome | Coronavirus Infection | Covid-19 | COVID | Acute Respiratory Distress Syndrome | Coronavirus | Ards | Severe Acute Respiratory Syndrome Coronavirus 2 | Sars-CoV2

United States, Brazil
Massachusetts General Hospital
Marino Foundation

Completed

Development of a Resiliency Training Program for Parents of Children With Specific Learning Disabilities (SPLD)

Stress

United States
Pfizer

Completed

Long-Term Open-Label Extension Trial for Subjects Completing the Phase 3 Trial of Fesoterodine (SP583) for the Treatment of Overactive Bladder Syndrome

Overactive Bladder Syndrome

Germany
Pfizer

Completed

A Multicenter Trial to Investigate Fesoterodine Sustained Release in Overactive Bladder Syndrome

Overactive Bladder Syndrome

Germany
Yonsei University

Completed

Lower Femtosecond Laser Energy Levels Lead to Better Visual Recovery After Small-incision Lenticule Extraction for Myopia

Myopia

Korea, Republic of
Fundación de investigación HM
Michael J. Fox Foundation for Parkinson's Research; Hospital San Carlos, Madrid and other collaborators

Completed

Prevention of Levodopa-induced Dyskinesias by Transcranial Static Magnetic Field Stimulation (tSMS)

Parkinson's Disease | Dyskinesia, Medication-Induced

Spain
Aravax Pty Ltd

Recruiting

A Safety and Efficacy Study of PVX108 in Children and Adolescents With Peanut Allergy

Immune System Diseases | Peanut Hypersensitivity | Peanut Allergy | Peanut-Induced Anaphylaxis

United States, Australia
Stryker Orthopaedics

Completed

ABC/Trident® Ceramic Post Approval Study

Arthroplasty, Replacement, Hip

United States
International AIDS Vaccine Initiative
Coalition for Epidemic Preparedness Innovations

Recruiting

A Lassa Fever Vaccine Trial in Adults and Children Residing in West Africa

Lassa Fever

Ghana, Liberia, Nigeria
Chulalongkorn University

Not yet recruiting

Efficacy of Adjunctive Low-Level Light Therapy to Intense Pulsed Light for Meibomian Gland Dysfunction

MGD-Meibomian Gland Dysfunction
University Hospital Center of Martinique

Recruiting

Validation of a Screening Tool for Swallowing Disorders for the Elderly (DéGluT'G)

Dysphagia | Swallowing Disorder

France
Second Affiliated Hospital, School of Medicine,...

Recruiting

Efficacy of Intense Pulsed Light in the Treatment of Recurrent Chalazia

Chalazion

China
Kiniksa Pharmaceuticals, Ltd.

Completed

Study to Assess the Safety, Pharmacokinetics, and Efficacy of KPL-404 in Participants With Rheumatoid Arthritis With Inadequate Response or Intolerance to at Least One Biologic Disease-modifying Anti-rheumatic Drug or a Janus Kinase Inhibitor

Arthritis, Rheumatoid

United States, Poland, Hungary, Georgia, Czechia, South Africa, Bulgaria
Sahlgrenska University Hospital, Sweden

Active, not recruiting

Rupture of Thumb's Long Extensor Tendon After Fracture of the Distal Radius, Study of Muscle and Tendon Pathology

Distal Radius Fractures | Pathology | Tendon Injury - Hand

Sweden
Selecta Biosciences, Inc.

Completed

A Study to Compare the Efficacy of SEL-212 to KRYSTEXXA® in Gout Participants Refractory to Conventional Therapy (COMPARE)

Chronic Gout

United States
Otsuka Pharmaceutical Co., Ltd.

Completed

A Long-Term Extension Trial From Late Phase II of SPM 962 in Advanced Parkinson's Disease Patients

Parkinson's Disease

Japan
Centre de Recherche Rhumatologique et Thermal

Completed

Crenobalneotherapy in the Treatment of Chronic Venous Insufficiency

Balneology
Allergy Therapeutics

Completed

Assessment of the Contribution of Monophosphoryl Lipid A (MPL) to a Tree Pollen Allergy Vaccine

Type I Hypersensitivity

Canada
Allergy Therapeutics

Completed

Efficacy and Safety/Tolerability of Ragweed MATA MPL

Type I Hypersensitivity

Canada, United States
IDRI
Bill and Melinda Gates Foundation

Completed

Safety Study to Evaluate the Leish-111f + MPL-SE Vaccine in the Prevention of Cutaneous Leishmaniasis in Healthy Subjects Previously Exposed to the Leishmania Parasite

Cutaneous Leishmaniasis

Colombia
Apollo Therapeutics Ltd

Not yet recruiting

A Study to Investigate APL-4098 Alone and/or in Combination With Azacitidine in R/R AML and High-Risk MDS

Myelodysplastic Syndrome With Excess Blasts | Acute Myeloid Leukemia, in Relapse | Acute Myeloid Leukemia Refractory | Myelodysplastic Syndrome Acute Myeloid Leukemia
Beckley Psytech Limited

Completed

Single Ascending Dose Study With BPL-003 in Healthy Subjects

Pharmacokinetics in Healthy Adults

United Kingdom
San Diego State University
National Institute of Mental Health (NIMH)

Completed

Suicide Prevention for Sexual and Gender Minority Youth (Case Series)

Suicide

United States
Wei Chen

Enrolling by invitation

Effect of Exercise on Indocyanine Green (ICG) Lymphography Imaging

Lymphedema

United States
Mary H. Teng

Completed

Sensory Motor Lateralization as Handwriting Intervention in School-Based OT (SML)

Developmental Dysgraphia
Queen Mary University of London
Metagenics, Inc.

Unknown

SPM Regulation by Fish Oil Supplements in Healthy Volunteers

Healthy Volunteers

United Kingdom
Stefan Woehrl
Medical University of Vienna

Completed

Skin Testing With Recombinant Bet v 1 and Hypoallergenic Recombinant Bet v 1 Fragments

Atopic Dermatitis

Austria
UCB Pharma

Completed

A Trial to Compare the Efficacy of Rotigotine Transdermal Patch to That of Ropinirole on Early Morning Motor Impairment and Sleep Disorders in Subjects With Early-Stage, Idiopathic Parkinson's Disease

Parkinson's Disease

Germany
UCB Pharma

Completed

A Trial to Assess the Efficacy and Safety of SPM 927 (Lacosamide) in Subjects With Painful Distal Diabetic Neuropathy

Diabetic Neuropathy

Germany
IDRI

Completed

Safety and Immunogenicity of the LEISH-F2 + MPL-SE Vaccine With SSG for Patients With PKDL

Post Kala Azar Dermal Leishmaniasis

Sudan
Shanghai Jiao Tong University School of Medicine

Completed

Effect of Protein-Restricted Diet on Nitrogen Balance and Residual Renal Function in Peritoneal Dialysis (PD) Patients

Peritoneal Dialysis | Chronic Kidney Disease
IDRI
Bill and Melinda Gates Foundation

Completed

Study to Evaluate the Leish-111F + MPL-SE Vaccine in the Treatment of Mucosal Leishmaniasis

Leishmaniasis, Mucocutaneous

Peru
IDRI
Bill and Melinda Gates Foundation

Completed

Study to Evaluate the Leish-111f + MPL-SE Vaccine in Healthy Adults Not Previously Exposed to Leishmania Parasite

Cutaneous Leishmaniasis

Colombia

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