Search clinical trials for: Setmelanotide 3mg daily

Total 14181 results

Rhythm Pharmaceuticals, Inc.

Completed

Phase 3 Crossover Trial of Two Formulations of Setmelanotide in Patients With Specific Gene Defects in the MC4R Pathway

Bardet-Biedl Syndrome | POMC Deficiency

Netherlands, United States, Germany, Canada, Puerto Rico, United Kingdom
Rhythm Pharmaceuticals, Inc.

Approved for marketing

An Expanded Access Protocol for Setmelanotide for Treatment of Bardet-Biedl Syndrome (BBS)

Obesity | Bardet-Biedl Syndrome (BBS)
Rhythm Pharmaceuticals, Inc.

Completed

Open-Label Study of Setmelanotide in Hypothalamic Obesity

Hypothalamic Obesity

United States
Rhythm Pharmaceuticals, Inc.

Completed

A Phase 1 Study to Evaluate the Pharmacokinetics of Setmelanotide in Subjects With Varying Degrees of Renal Impairment

Renal Insufficiency

United States
Rhythm Pharmaceuticals, Inc.

Recruiting

EMANATE: A Study of Setmelanotide in Patients With Specific Gene Variants in the MC4R Pathway

Obesity | Genetic Obesity

United States, Spain, Germany, Netherlands, United Kingdom, Greece, Puerto Rico, Canada, France, Israel
Rhythm Pharmaceuticals, Inc.

Active, not recruiting

Long Term Extension Trial of Setmelanotide

Obesity Associated With Defects in Leptin-melanocortin Pathway

United States, Netherlands, Canada, Germany, United Kingdom, France, Greece, Spain
Rhythm Pharmaceuticals, Inc.

Active, not recruiting

DAYBREAK: A Study of Setmelanotide in Patients With Specific Gene Variants in the MC4R Pathway

Genetic Obesity

United States, Spain, Netherlands, Germany, United Kingdom, Canada, Israel, Greece
Rhythm Pharmaceuticals, Inc.

Completed

Setmelanotide in a Single Patient With Partial Lipodystrophy

Obesity | Hypertriglyceridemia

United States
Rhythm Pharmaceuticals, Inc.

Completed

Phase 2 Trial to Evaluate Safety and Efficacy of Setmelanotide (RM-493) in Obese Participants With Prader-Willi Syndrome

Prader-Willi Syndrome

United States
Rhythm Pharmaceuticals, Inc.

Completed

Setmelanotide (RM-493), Melanocortin-4 Receptor (MC4R) Agonist, in Bardet-Biedl Syndrome (BBS) and Alström Syndrome (AS) Participants With Moderate to Severe Obesity

Bardet Biedl Syndrome (BBS) | Alström Syndrome (AS)

United States, United Kingdom, France, Canada, Puerto Rico, Spain
Rhythm Pharmaceuticals, Inc.

Completed

Phase 1b/2a Study to Evaluate Safety and Efficacy of Setmelanotide in Obese Patients

Overweight and Obesity

United States
Rhythm Pharmaceuticals, Inc.

Completed

Setmelanotide for the Treatment of Leptin Receptor (LEPR) Deficiency Obesity

Leptin Receptor Deficiency Obesity

Netherlands, Germany, United Kingdom, Canada, France, Réunion
Rhythm Pharmaceuticals, Inc.

Completed

Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of RM-493 Administered to Healthy, Obese, Non-diabetic Volunteers

Overweight | Obese
GlaxoSmithKline

Completed

A Study in Asthmatics to Determine the Efficacy and Dose Response of Repeat Doses of GW870086X on Forced Expiratory Volume in 1 Second (FEV1)

Asthma

Germany, South Africa, Bulgaria
Rhythm Pharmaceuticals, Inc.

Completed

Setmelanotide Phase 2 Treatment Trial in Participants With Rare Genetic Disorders of Obesity

Obesity | Genetic Obesity | Obesity Due to Melanocortin 4 Receptor Deficiency

United States, United Kingdom, Germany, Netherlands, France, Canada, Greece, Israel, Spain
Charite University, Berlin, Germany

Unknown

RM-493 Treatment Trial in Proopiomelanocortin (POMC) Deficient Patients

Homozygous or Compound Heterozygous POMC, LEPR or PCSK1 Gene Mutation

Germany
Rhythm Pharmaceuticals, Inc.

Completed

Setmelanotide in Pediatric Patients With Rare Genetic Diseases of Obesity

Bardet-Biedl Syndrome | POMC Deficiency Obesity | PCSK1 Deficiency Obesity | LEPR Deficiency Obesity

United States, Australia, Spain, United Kingdom
Rhythm Pharmaceuticals, Inc.

Completed

Setmelanotide for the Treatment of Early-Onset Pro-Opiomelanocortin (POMC) Deficiency Obesity

Pro-opiomelanocortin (POMC) Deficiency Obesity

Belgium, United States, Canada, France, Germany, Spain, United Kingdom
J2H Biotech

Completed

Phase 1 Study to Investigate Safety, Tolerability, PK/PK of J2H-1702 in Healthy Males

Non-alcoholic Steatohepatitis

Korea, Republic of
Rhythm Pharmaceuticals, Inc.

Completed

Phase 2 Study to Evaluate Safety and Efficacy of RM-493 in Obese Participants

Overweight

United States
Barbara Ann Karmanos Cancer Institute
National Cancer Institute (NCI)

Completed

Pyrazoloacridine in Treating Patients With Advanced Non-small Cell Lung Cancer

Lung Cancer

United States
Rhythm Pharmaceuticals, Inc.

Enrolling by invitation

A Trial of Setmelanotide in Acquired Hypothalamic Obesity

Hypothalamic Obesity

United States, Canada, Japan, United Kingdom, Germany, Netherlands
Johnson & Johnson Pharmaceutical Research & Development...

Terminated

An Efficacy and Safety Study of JNJ-26113100 in the Treatment of Adult Atopic Dermatitis

Atopic Dermatitis

United States
Otsuka Pharmaceutical Co., Ltd.

Completed

A Phase 2 Trial of OPC-64005 for Major Depressive Disorder

Major Depressive Disorder

Japan
Kowa Company, Ltd.

Completed

A Phase III Confirmatory Study of K-877 Extended Release Tablet

Dyslipidemias

Japan
Kyowa Kirin Co., Ltd.
Kyowa Hakko Kirin China Pharmaceutical Co., LTD.

Completed

Pharmacokinetic Study of KHK7580 in Healthy Adult Volunteers

Healthy Volunteer

China
Ono Pharmaceutical Co. Ltd

Terminated

A Study of ONO-7475 in Patients With Acute Leukemias

Myelodysplastic Syndromes | Acute Leukemia

United States
Manal Abdelmalek

Completed

JKB-121 for the Treatment of Nonalcoholic Steatohepatitis

Nonalcoholic Steatohepatitis

United States
Celgene

Withdrawn

A Phase 2 Study With CC-220 in Skin Sarcoidosis

Sarcoidosis
Inflazyme Pharmaceuticals Ltd

Completed

Control of Asthma Patients Symptomatic on Inhaled Corticosteroids

Asthma

United States
Kowa Company, Ltd.

Recruiting

A Phase III Confirmatory Study of K-877 (Pemafibrate) in Patients With Hypercholesterolemia and Statin Intolerance

Hypercholesterolemia

Japan
Basilea Pharmaceutica

Completed

Derazantinib and Atezolizumab in Patients With Urothelial Cancer (FIDES-02)

Urothelial Carcinoma

United Kingdom, Korea, Republic of, Italy, Canada, France, Spain, Germany, United States, Hungary, Australia, Poland, Switzerland, Czechia, Austria
Eli Lilly and Company

Completed

Enzastaurin Before and Concomitant With Radiation, Followed by Enzastaurin in Participants With Newly Diagnosed Glioblastoma

Glioblastoma Multiforme

Germany
CDA Research Group, Inc.

Completed

3VM for Treatment of Chronic Osteoarthritis Knee Pain

Arthritis, Degenerative

United States
Kowa Company, Ltd.

Completed

A Phase III Long Term Study of K-877 Extended Release Tablet

Dyslipidemias

Japan
Medical University of South Carolina

Completed

The Effect of Minocycline and N-acetylcysteine for the Treatment of Fibromyalgia

Fibromyalgia

United States
Bausch Health Americas, Inc.

Completed

Rifaximin Soluble Solid Dispersion (SSD) Tablets Plus Lactulose for the Treatment of Overt Hepatic Encephalopathy (OHE) (OHE)

Overt Hepatic Encephalopathy

United States
Maruho Co., Ltd.

Completed

Open-label Study of ASP2151 in Herpes Simplex Patients

Herpes Simplex

Japan
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Pharmacokinetic and Pharmacodynamic Study of Once-Daily and Twice-Daily Dosing With Canagliflozin in Healthy Adult Volunteers

Healthy
GlaxoSmithKline

Completed

A Comparison of Atorvastatin and Glimepiride Fixed Dose Combination and Atorvastatin and Glimepiride Loose Combination in the Treatment of Patients With Type 2 Diabetes Mellitus

Diabetes Mellitus, Type 2

Korea, Republic of, Malaysia, Philippines, Thailand, Russian Federation, Mexico
University of Alberta

Completed

Study of Dietary Intervention Under 100 MMOL in Heart Failure (SODIUM-HF)

Heart Failure

Canada
Novartis

Completed

Efficacy of DNK333 in Patients With COPD and Cough

Chronic Obstructive Pulmonary Disease

United Kingdom, Netherlands
Novartis Pharmaceuticals

Terminated

Systemic Corticosteroids Avoidance Study in Severe Asthma Patients

Asthma

Germany, Belgium, South Africa, United States, Russian Federation, France, Slovakia, Spain, Thailand, Czechia, Greece, Argentina, Peru, United Kingdom, Bulgaria, Turkey, Hungary, Vietnam, Philippines, Colombia, Chile
Helixmith Co., Ltd.

Completed

Safety Study of Gene Therapy in Treating Lower Leg Ischemia

Critical Limb Ischemia

United States
Kowa Research Institute, Inc.

Completed

Drug-Drug Interaction Study to Assess the Effects of Steady State Pitavastatin 4 mg or Rosuvastatin 40 mg on Steady-State Warfarin in Healthy Adult Volunteers

Healthy

United States
Tibotec Pharmaceuticals, Ireland

Completed

A Study to Determine the Antiviral Activity of TMC310911 When Administered With Ritonavir in Treatment-Naive Human Immunodeficiency Virus - Type 1 (HIV-1) Infected Patients

Human Immunodeficiency Virus Type 1

Germany
Pfizer

Completed

Multiple Oral Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of PF-04878691

Hepatitis C Virus

United States
University of Edinburgh
NHS Lothian

Completed

Cardiovascular Effects of Apelin In Healthy Volunteers

Healthy

United Kingdom
Cristcot LLC
Cristcot HCA LLC

Recruiting

Phase 3 Study to Evaluate the Safety and Efficacy of Hydrocortisone Acetate Suppositories

Ulcerative Proctitis

United States, Georgia, Denmark, South Africa, Vietnam, Lebanon, Jordan, Saudi Arabia, Philippines, Poland, France, India, Romania, Bulgaria, Moldova, Republic of, Turkey
Radboud University Medical Center
Astellas Pharma Europe B.V.

Completed

Personalizing Enzalutamide Therapy by Understanding the Relation Between Tumor mRNAs, miRNAs and Treatment Response (ILUMINATE)

Metastatic Castration Resistant Prostate Cancer

Netherlands

Search clinical trials for: Setmelanotide 3mg daily

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