Search clinical trials for: Steroid Synthesis Inhibitors

Total 67456 results

Merck Sharp & Dohme LLC

Completed

MK-0954E Study in Participants With Hypertension (MK-0954E-357)

Hypertension
Allergan

Completed

Patient Satisfaction Study of Combined Facial Treatment With BOTOX® Cosmetic, JUVÉDERM® and LATISSE® (HARMONY Study)

Glabellar Lines | Nasolabial Fold | Crow's Feet Lines | Facial Rhytides

United States
Merck Sharp & Dohme LLC
Pfizer

Completed

A Study To Evaluate The Efficacy And Safety Of Ertugliflozin In Participants With Type 2 Diabetes Mellitus And Inadequate Glycemic Control On Metformin Monotherapy (MK-8835-007).

Type 2 Diabetes Mellitus
Radboud University Medical Center
The PATH Malaria Vaccine Initiative (MVI); QIMR Berghofer Medical Research...

Completed

Controlled Human Malaria Infection Model for Evaluation of Transmission-Blocking Interventions - Study 1 (CHMI-trans1)

Malaria

Netherlands
Masonic Cancer Center, University of Minnesota

Completed

T-Regulatory Cell Infusion Post Umbilical Cord Blood Transplant in Patients With Advanced Hematologic Cancer

Lymphoma | Myelodysplastic Syndromes | Leukemia | Multiple Myeloma | Plasma Cell Neoplasm

United States
University College, London

Completed

Gliadel Wafer and Fluorescence-Guided Surgery With 5-ALA Followed by Radiation Therapy And Temozolomide in Treating Patients With Primary Glioblastoma

Glioblastoma

United Kingdom
Helsinki University Central Hospital

Completed

A Study on Molecular Genetics of Drug Responsiveness in Essential Hypertension (GENRES)

Hypertension | Pharmacogenetics

Finland
University of Washington
National Cancer Institute (NCI)

Completed

Perioperative Therapy for Resectable Pancreatic Cancer

Adenocarcinoma of the Pancreas | Stage IIA Pancreatic Cancer | Stage IIB Pancreatic Cancer | Stage IA Pancreatic Cancer | Stage IB Pancreatic Cancer

United States
Sunovion

Completed

Lurasidone - A 6-week Study of Patients With Bipolar I Depression (Add-on)

Bipolar Depression

United States, Czech Republic, India, France, Germany, Poland, Romania, Russian Federation, South Africa, Ukraine
University of Cincinnati
Patty Brisben Foundation For Women's Sexual Health

Unknown

Trigger Point Injections and Pelvic Rehabilitation for the Treatment of Pelvic Floor Myalgia and Sexual Pain

Dyspareunia

United States
Centers for Disease Control and Prevention
Ministry of Health and Population, Malawi

Completed

Assessing the Efficacy of Four Drug Combinations as the Next First-line Therapy for Uncomplicated Malaria in Malawi

Malaria, Falciparum

Malawi
Hoffmann-La Roche
Aspreva Pharmaceuticals

Completed

A Study of Mycophenolate Mofetil (CellCept) in Management of Patients With Lupus Nephritis.

Lupus Nephritis

Belgium, Germany, Italy, Spain, Canada, France, Portugal, United States, Greece, Mexico, United Kingdom, Australia, China, Hungary, Argentina, Brazil, Czech Republic
RWTH Aachen University
Air Liquide Santé International

Completed

Depth of Hypnosis and Postoperative Nausea and Vomiting During Xenon Anaesthesia (XABP)

Postoperative Nausea | Postoperative Vomiting | Depth of Anaesthesia | Anaesthetics Gases, Xenon | Anaesthetics Volatile, Sevoflurane

Germany
University Hospital, Aker
University of Oslo; AstraZeneca; Norwegian University of Science and Technology; Diakonhjemmet Hospital and other collaborators

Completed

Treatment of Schizophrenia With an Omega-3 Fatty Acid (EPA) and Antioxidants

Psychotic Disorders | Schizophrenia | Schizoaffective Disorder | Schizophreniform Disorders

Norway
Aga Khan University Hospital, Pakistan

Not yet recruiting

Dexamethasone or Dexmedetomidine as Adjunct in Fascia Iliaca Block During Positioning for Sub-arachnoid Block & Post-operative Analgesia After Femur Neck Fracture Surgery: A Randomized Control Trial

Post Operative Pain
National Cancer Institute, Egypt

Recruiting

Attenuation of Airway and Cardiovascular Responses to Extubation in Chronic Smokers

Hemodynamic | Airway Responses

Egypt
Zhenjiang First People's Hospital

Completed

Safety Study of Dexmedetomidine in Elderly Under General Anesthesia

Hip Fractures | Hip Disease

China
Calithera Biosciences, Inc

Completed

Study of the Glutaminase Inhibitor CB-839 in Solid Tumors

Renal Cell Carcinoma | Non Small Cell Lung Cancer | Mesothelioma | Solid Tumors | Triple-Negative Breast Cancer | Fumarate Hydratase (FH)-Deficient Tumors | Succinate Dehydrogenase (SDH)-Deficient Gastrointestinal Stromal Tumors (GIST) | Succinate Dehydrogenase (SDH)-Deficient Non-gastrointestinal... and other conditions

United States
Menoufia University

Active, not recruiting

Subtenon and Intravenous Dexmedetomidine Effect on Patients Undergoing Cataract Surgery

Acute Postoperative Pain

Egypt
Pontificia Universidad Catolica de Chile

Completed

Effect of Dexmedetomidine on Postoperative Glucose and Insulin Levels.

Insulin Resistance | Glucose Intolerance | Bariatric Surgery Candidate
Yeditepe University

Completed

Hydroxyzine Dihydrochloride Premedication is a Necessity for Strabismus Surgery

Strabismus | Reflex, Oculocardiac | Hydroxyzine | Bradycardia Sinus

Turkey
University of Athens

Unknown

Effect of Perioperative iv Dexmedetomidine vs. Lidocaine on Postoperative Pain, Analgesic Consumption and Recovery After Abdominal Gynaecological Surgery

Hysterectomy | Myomectomy

Greece
University of Alabama at Birmingham
National Center for Research Resources (NCRR)

Completed

The Effect of Sedation on Eye Movements (Eye Movement)

Saccadic Eye Movements

United States
Hospira, now a wholly owned subsidiary of Pfizer

Completed

Pharmacokinetics and Pharmacodynamics of Dexmedetomidine in Pediatrics Subjects

Intubated and Mechanically Ventilated Pediatric Subjects

United States, Guatemala
Southern California Institute for Research and...
National Institute of Mental Health (NIMH); University of California, Irvine

Unknown

Developing Anesthesia as Post Traumatic Stress Disorder (PTSD) Therapy

Healthy

United States
Maharashtra University of Health Sciences

Completed

Dexmedetomidine Verses Propofol for Paediatric MRI Brain (DPMP)

Brain Diseases

India
Nationwide Children's Hospital

Completed

Dexmedetomidine Versus Fentanyl Following Pressure Equalization Tube Placement

Chronic Otitis Media

United States
Affiliated Cancer Hospital & Institute of Guangzhou...

Recruiting

The Effects of Subanesthetic S-ketamine on Postoperative Delirium and Cognitive Function in the Elderly Undergoing Non-cardiac Thoracic Surgery (SKED)

Postoperative Delirium | Elderly Patients

China
Benha University

Not yet recruiting

Dexamethasone and Dexmedetomidine as an Adjuvant to Spinal Anesthesia for Elective Caesarean Sections

Pain, Postoperative
Ain Shams University

Completed

Dexmedetomidine Compared to Ketofol for Sedation in Paediatrics

Vital Signs

Egypt
Anqing Municipal Hospital
The First Affiliated Hospital of Anhui Medical University

Completed

Dexmedetomidine Combined With Lidocaine Infusion Affect Inflammation Cytokines

Anesthesia; Reaction

China
Duke University

Terminated

Pain, Agitation and Delirium (PAD) Protocol in the Duke CICU

Critical Illness | Deep Sedation | Ventilators, Mechanical

United States
Chuncheon Sacred Heart Hospital
Hallym University

Completed

The Effect of Dexmedetomidine for Suprascapular Nerve Block With Axillary Nerve Block

Postoperative Pain | Dexmedetomidine | Suprascapular Nerve Block | Arthroscopic Rotator Cuff Repair | Axillary Nerve Block | Pain Related Cytokine

Korea, Republic of
Suez Canal University

Unknown

Adjuvant to General Anesthesia in Patients Undergoing Major Abdominal Surgeries (Adjuvant)

Stress Related Disorder
Hospira, now a wholly owned subsidiary of Pfizer

Completed

Open-Label, Safety Study Evaluating the Use of Dexmedetomidine in Pediatric Subjects Undergoing Procedure-Type Sedation

Ultrasound | CT Scans | MRIs

United States, Puerto Rico
University Hospital Inselspital, Berne
GE Healthcare

Completed

Effects of Two Different Sedation Regimes on Auditory Evoked Potentials and Electroencephalogram (EEG)

Critical Care | Conscious Sedation | Deep Sedation

Switzerland
National Cancer Institute, Egypt

Completed

Dexmedetomidine-Propofol Versus Ketamine-Propofol for Sedation of CT Guided Bone Biopsy

Sedation

Egypt
Joseph Cravero

Completed

A Pilot Study of Dexmedetomidine-Propofol in Children Undergoing Magnetic Resonance Imaging

Epilepsy | Cerebral Palsy | Developmental Delay

United States
GCS Ramsay Santé pour l'Enseignement et la Recherche
Euraxi Pharma

Completed

Extension of Analgesia by Combined Injection of Dexamethasone and Dexmedetomidine After Arthroscopic Shoulder Surgery (INDEX)

Analgesia

France
AHEPA University Hospital
Skylitseio General Hospital

Completed

Beta Blockers Plus Intravenous Flecainide for Paroxysmal Atrial Fibrillation: a Real-world Chios Registry (BETAFLEC-CHIOS) (BETAFLEC-CHIOS)

Atrial Fibrillation | Arrhythmias, Cardiac

Greece
Norma Osama Abdalla Zayed
Abdelhamid, Bassant Mohamed, M.D.

Completed

Effect of IV Infusion of Lidocaine Compared to IV Infusion of Dexmedetomidine on Proinflammatory Cytokines

Inflammatory Response

Egypt
Beth Israel Deaconess Medical Center

Completed

Dexmedetomidine and IV Acetaminophen for the Prevention of Postoperative Delirium Following Cardiac Surgery (DEXACET)

Delirium

United States
Postgraduate Institute of Medical Education and...

Completed

Comparison of Opioid Based and Opioid Free Anaesthesia in Transsphenoidal Surgery

Opioid Free Anaesthesia

India
Xu Siqi

Completed

Effect of Lidocaine Plus Dexmedetomidine Infusion on PONV

Dexmedetomidine | Nausea and Vomiting, Postoperative | Lidocaine

China
Cairo University

Unknown

Comparison of Different Doses of Dexmedetomidine Effect in the Duration of Spinal Anesthesia

Spinal Anesthesia Duration

Egypt
National Cancer Institute (NCI)

Completed

Temsirolimus With or Without Cetuximab in Patients With Recurrent and/or Metastatic Head and Neck Cancer Who Did Not Respond to Previous Therapy (MAESTRO HN)

Recurrent Hypopharyngeal Squamous Cell Carcinoma | Recurrent Laryngeal Squamous Cell Carcinoma | Recurrent Oropharyngeal Squamous Cell Carcinoma | Salivary Gland Squamous Cell Carcinoma | Recurrent Lip and Oral Cavity Squamous Cell Carcinoma | Recurrent Nasopharyngeal Keratinizing Squamous... and other conditions

United States, China
National Cancer Institute (NCI)

Completed

Temsirolimus, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma

United States
Lewai Sharki Abdulaziz, MSc PhD
Al-Kindy College of Medicine; Research & Development Directorate, Ministry...

Completed

Screening for Colorectal Cancer in Average and High Risk Population

Colorectal Neoplasms | Colorectal Cancer | Adenomatous Polyp of Colon

Iraq
National Cancer Institute (NCI)

Active, not recruiting

Combination Chemotherapy in Treating Young Patients With Newly Diagnosed High-Risk B Acute Lymphoblastic Leukemia and Ph-Like TKI Sensitive Mutations

B Acute Lymphoblastic Leukemia | Central Nervous System Leukemia | Testicular Leukemia | B Acute Lymphoblastic Leukemia, BCR-ABL1-Like

United States, Canada, Puerto Rico, Australia, New Zealand, Switzerland, Ireland
Children's Oncology Group
National Cancer Institute (NCI)

Active, not recruiting

Risk-Adapted Chemotherapy in Treating Younger Patients With Newly Diagnosed Standard-Risk Acute Lymphoblastic Leukemia or Localized B-Lineage Lymphoblastic Lymphoma

Acute Lymphoblastic Leukemia | Down Syndrome | Philadelphia Chromosome Positive | Childhood B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1 | Childhood B Acute Lymphoblastic Leukemia | Adult B Lymphoblastic Lymphoma | Ann Arbor Stage I B Lymphoblastic Lymphoma | Ann Arbor Stage... and other conditions

United States, Canada, Puerto Rico, Australia, New Zealand, Switzerland, Ireland

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