Search clinical trials for: Sustained-release oral dalfampridine

Total 442 results

Sheba Medical Center

Unknown

Efficacy of Dalfampridine on Upper Extremity Function in Patients With MS

Multiple Sclerosis

Israel
Luye Pharma Group Ltd.

Recruiting

Safety, Tolerability and Pharmacokinetic of Multiple-ascending Doses of LPM3770164 in Healthy Subjects

Tardive Dyskinesia | Huntington Disease

China
Luye Pharma Group Ltd.

Completed

A Dose-escalation Study to Evaluate the Safety, Tolerability and Pharmacokinetic of LPM3770164 in Healthy Subjects

Tardive Dyskinesia | Huntington Disease

China
Luye Pharma Group Ltd.

Recruiting

A Study to Evaluate Efficacy and Safety of Toludesvenlafaxine Hydrochloride Sustained-release Tablets in Generalized Anxiety Disorder.

Generalized Anxiety Disorder

China
Jiangsu HengRui Medicine Co., Ltd.

Active, not recruiting

A SHR0302 BA Study on Healthy Subjects

Autoimmune Diseases

China
Shanghai Mental Health Center

Not yet recruiting

Efficacy and Safety of Toluedesvenlafaxine Hydrochloride Extended-release Tablets in Somatic Symptoms of Depression

Somatic Symptom

China
United Therapeutics

Completed

FREEDOM-C: Oral Treprostinil in Combination With an Endothelin Receptor Antagonist (ERA) and/or a Phosphodiesterase-5 (PDE-5) Inhibitor for the Treatment of Pulmonary Arterial Hypertension (PAH)

Pulmonary Hypertension

United States, United Kingdom, Canada, Spain, Australia, Israel, Germany, Belgium, France, Austria, Italy, Poland, Ireland, Netherlands
Riphah International University

Completed

Myofascial Release and Sustained Stretching in Spastic CP Children

Cerebral Palsy

Pakistan
Luye Pharma Group Ltd.

Not yet recruiting

To Evaluate the Long-term Efficacy and Safety of Toludevenlafaxine Hydrochloride Sustained-release Tablets

Major Depressive Disorder
Jiangsu HengRui Medicine Co., Ltd.

Unknown

Clinical Trial of Systolic Heart Failure Treatment of IvabRadine Hemisulfate Sustained-release Tablets （FIRST） (FIRST)

Chronic Systolic Heart Failure

China
Second Affiliated Hospital of Soochow University

Active, not recruiting

A Clinical Study of Dihydroergotine Mesylate Extended-release Tablets for the Treatment of Drooling in Parkinson's Disease.

Salivation in Parkinson's Disease

China
United Therapeutics

Completed

FREEDOM - M: Oral Treprostinil as Monotherapy for the Treatment of Pulmonary Arterial Hypertension (PAH)

Pulmonary Hypertension

United States, China, Israel, Belgium, Canada, France, India, Mexico, Austria, Italy, Netherlands, Poland, Puerto Rico
Kessler Foundation
National Institute on Disability, Independent Living, and Rehabilitation... and other collaborators

Completed

Combination Therapy With Dalfampridine and Locomotor Training for Chronic, Motor Incomplete Spinal Cord Injury

Spinal Cord Injury

United States
Otsuka Pharmaceutical Development & Commercialization...

Completed

Safety and Efficacy Study of Centanafadine Sustained-Release (CTN SR) in Adults With Attention-Deficit Hyperactivity Disorder (ADHD)

Attention Deficit Disorder With Hyperactivity

United States
University Health Network, Toronto
Canadian Society of Hospital Pharmacists

Withdrawn

Dosing Intervals of Opioid Medication for Chronic Pain

Chronic Pain

Canada
Overseas Pharmaceuticals, Ltd.
GX pharma technology (beijing) Co., Ltd

Active, not recruiting

An Open Label, Balanced, Randomized, 3×3 Latin Square Design Comparing of Brivaracetam Sustained-release Tablets and Brivaracetam Tablets in the Oral Comparative Pharmacokinetic(PK) Study in Chinese Healthy Adult Subjects Under Fasting Conditions.

Partial Seizure

China
Ain Shams University

Recruiting

Dalfampridine in Egyptian Patients With Multiple Sclerosis

Multiple Sclerosis

Egypt
M.A. Med Alliance S.A.

Active, not recruiting

SUCCESS (SelUtion, Safety, effiCaCy, hEalth economicS and promS) PTA Study (SUCCESS PTA)

Peripheral Artery Disease

Germany
Shanghai Mental Health Center
Yantai University

Recruiting

Assessing Dopamine Transporter Occupancy in the Patients With Depression Brain With Toludesvenlafaxine Hydrochloride Extended-Release Tablets Using 11C-CFT Positron Emission Tomography (PET)

Major Depressive Disorder

China
Jiangsu HengRui Medicine Co., Ltd.

Active, not recruiting

Clinical Study of Retagliptin Phosphate Combined With Metformin in the Treatment of Type 2 Diabetes

Type 2 Diabetes

China
Shanghai Mental Health Center
Yantai University

Completed

Assessing Dopamine Transporter Occupancy in the Healthy Adult Brain With Toludivenlafaxine Hydrochloride Extended-Release Tablets Using 11C-CFT Positron Emission Tomography (PET)

Major Depressive Disorder

China
LG Life Sciences

Completed

Safety and Efficacy of SR-hGH (Sustained-release Human Growth Hormone, Declage Inj.)

Growth Hormone Deficiency
Riphah International University

Completed

Thrust Joint Manipulation and Reverse SNAGS (Sustained Natural Apophyseal Glides) in Cervicogenic Headache

Cervicogenic Headache

Pakistan
Meda Pharmaceuticals

Completed

A Study to Evaluate Two Formulations of Carisoprodol in Subjects With Musculoskeletal Spasm of the Lower Back

Lower Back Pain

United States
LG Chem

Unknown

Food-effect Bioavailability of Fixed Dose Combination Zemimet® SR Tab. 50/1000 mg Under Fed and Fasting Conditions

Type2 Diabetes
National Eye Institute (NEI)

Completed

Ganciclovir Implant Study for Cytomegalovirus Retinitis

HIV Infections | Acquired Immunodeficiency Syndrome | Cytomegalovirus Retinitis
Sun Yat-sen University

Completed

Efficacy and Safety of Tacrolimus Sustained-release Capsules in Induction Treatment in Refractory Lupus Nephritis

Nephritis, Lupus

China
Biogen
Association for Functional Rehabilitation, Recreation and Applied Kinesiology...

Recruiting

TOPIK Study: A Study to Report Progressive Multifocal Leukoencephalopathy and Other Serious Opportunistic Infections in Natalizumab Treated Participants

Multiple Sclerosis

Czechia
Synchroneuron Inc.

Withdrawn

Trial of Oral SNC-102 in Subjects With Combat-Related Posttraumatic Stress Disorder (PTSD)

Posttraumatic Stress Disorders | Stress Disorders, Post-Traumatic | Post-Traumatic Stress Disorders | Post-Traumatic Stress Disorders, Combat-related
Eastern Hepatobiliary Surgery Hospital

Completed

Intraoperative Chemotherapy Against Hepatocellular Carcinoma Recurrence

Hepatocellular Carcinoma

China
United Therapeutics

Completed

A Dose Response Study of UT-15C SR in Patients With Exercise-Induced Pulmonary Hypertension

Pulmonary Hypertension

United States
Cornerstone Health Care, PA
Biogen

Completed

NAPS-MS: NAtalizumab Effects on Parameters of Sleep in Patients With Multiple Sclerosis Experiencing Fatigue or Sleepiness

Multiple Sclerosis, Relapsing-Remitting

United States
AbbVie

Available

Expanded Access to Bimatoprost (Durysta)

Open-angle Glaucoma
LG Life Sciences

Completed

BE Study of the Combinations of Gemigliptin 50mg and Metformin HCl Extended Release 1000mg in Comparison to Each Component Administered Alone.

Healthy

Korea, Republic of
Milton S. Hershey Medical Center

Terminated

A Single Dose Pharmaco-Diagnostic for Peripheral Nerve Continuity After Trauma

Nerve Injury

United States
Ochsner Health System
United Therapeutics

Completed

Safety Study of UT-15C SR (Oral Treprostinil) in Patients Undergoing a Lower Limb Endovascular Procedure

Critical Limb Ischemia

United States
University Hospital, Toulouse

Completed

Biomarkers and Response to Natalizumab for Multiple Sclerosis Treatment (Bionat2)

Multiple Sclerosis

France
Sun Yat-sen University

Not yet recruiting

The Effect of Metformin in Patients With Newly Diagnosed mHSPC

Metastatic Prostate Cancer

China
University of Florida
ALS Association

Active, not recruiting

Safety and Therapeutic Potential of the FDA-approved Drug Metformin for C9orf72 ALS/FTD

Frontotemporal Dementia | C9orf72 Amyotrophic Lateral Sclerosis (ALS)

United States
Sun Yat-sen University

Not yet recruiting

The Effect of Metformin in Patients With Metastatic Castration-resistant Prostate Cancer

Metastatic Prostate Cancer

China
Actavis Inc.

Completed

Comparative Study to Evaluate KADIAN and Avinza in Healthy Adults

Healthy

United States
Biogen

Completed

Exploratory Study to Assess the Effect of Fampridine (BIIB041) on Walking Ability and Balance in Participants With Multiple Sclerosis. (MOBILE)

Multiple Sclerosis

Sweden, United Kingdom, Netherlands, Belgium, Canada, Italy
Beijing Tiantan Hospital
CSPC Ouyi Pharmaceutical Co., Ltd.

Not yet recruiting

Efficacy of Pentoxifylline on Cerebrovascular Function in Patients With Cerebral Small Vessel Disease(PERFORM) (PERFORM)

Cerebral Small Vessel Diseases

China
ApoPharma

Completed

Pilot Study of the Pharmacokinetic Profile of Deferiprone Sustained-Release Formulation in Healthy Volunteers

Healthy

Canada
United Therapeutics

Completed

A Pharmacokinetic Substudy of the TDE-PH-304 Protocol

Pulmonary Arterial Hypertension

United States
Actavis Inc.

Completed

Comparison of One Morphine Sulfate Sustained-Release 200mg Capsule With Two 100 mg KADIAN Capsules Under Fasting Conditions

Healthy

United States
GlaxoSmithKline

Completed

Evaluation of Food Effect on the Pharmacokinetics of Sustained Release Metformin in Healthy Indian Volunteers

Diabetes Mellitus, Type 2
Actavis Inc.

Completed

Comparison of One Morphine Sulfate Sustained-Release 200 mg Capsule With Two 100 mg KADIAN Capsules on Applesauce

Healthy

United States
Biogen

Completed

A Safety and Efficacy Study of Oral Prolonged-Release Fampridine (BIIB041) in Japanese Participants With Multiple Sclerosis (MOTION - JAPAN)

Multiple Sclerosis | Relapsing-Remitting Multiple Sclerosis | Secondary Progressive Multiple Sclerosis | Multiple Sclerosis, Primary Progressive | Multiple Sclerosis, Remittent Progressive

Japan
Synchroneuron Inc.

Withdrawn

A Trial Evaluating the Efficacy, Safety, and Pharmacokinetics of SNC-102 in Subjects With Tourette Syndrome

Tourette Syndrome

United States

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