Search clinical trials for: T-cell activation test using intracellular markers

Total 52 results

University Hospital, Antwerp
Universiteit Antwerpen; AZ Jan Palfijn Gent

Not yet recruiting

Diagnosing Drug Allergy: the T is the Key (TAT)

Amoxicillin Allergy
Tongji University

Unknown

Evaluation of Immune Cell Markers in Diagnosis of Tuberculosis

Tuberculosis Infection

China
King's College London
King's College Hospital NHS Trust; University College London Hospitals; Cambridge... and other collaborators

Recruiting

The Clinical Impact of the Basophil Activation Test to Diagnose Food Allergy

Egg Allergy | Food Allergy | Food Allergy in Children | Milk Allergy | Food Allergy in Infants | Nut Allergy | Food Allergen Sensitisation

United Kingdom
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

REGulatory T Cells in Autism Induced by Maternal Immune Activation (REGAIN)

Autism Spectrum Disorder

France
Children's Hospital of Philadelphia

Available

Expanded Access Protocol Using Alpha/Beta T and CD19+ Depleted PBSC

Leukemia | Immunodeficiencies | Bone Marrow Failure Syndrome

United States
Shanghai Children's Medical Center
Chinese University of Hong Kong; Nanfang Hospital of Southern Medical University and other collaborators

Recruiting

TCDαβ/CD45RA Haploidentical Transplantation in Children With Leukemia

Relapsed Pediatric AML | Relapsed Pediatric ALL | Acute Graft-Versus-Host Disease (Gvhd) Grade IV (Diagnosis)

China
Imperial College London
Royal College of Surgeons, Ireland; University of Manchester

Enrolling by invitation

Improved Diagnostics in Food Allergy Study (ID-in-FA)

Food Allergy

United Kingdom, Ireland
Neena Kapoor, M.D.

Terminated

SCID Bu/Flu/ATG Study With T Cell Depletion

Severe Combined Immunodeficiency

United States
Lucid Diagnostics, Inc.

Recruiting

CLUE: CLinical Utility Study of EsoGuard (PR-0410)

Barrett Esophagus | Barretts Esophagus With Dysplasia | Esophagus Adenocarcinoma

United States
Maja Thiele
University of Oslo; Novo Nordisk A/S; University of Copenhagen; University of Southern... and other collaborators

Recruiting

Screening At-risk Populations for Hepatic Fibrosis With Non-invasive Markers (SIPHON)

Fibrosis | Liver Diseases, Alcoholic

Denmark
Children's Hospital of Philadelphia
University of California, San Francisco

Recruiting

Alpha/Beta T and CD19+ Depleted Peripheral Stem Cells for Patients With Primary Immunodeficiencies

Immunodeficiencies | Immune Dysregulation Syndromes

United States
Dragonfly Research, LLC

Completed

Humoral and T-Cell Responses to COVID-19 Vaccination in Multiple Sclerosis Patients Treated With Ocrelizumab Treated With Ocrelizumab or Natalizumab (OCR-VAX)

Pathologic Processes | Nervous System Diseases | Immune System Diseases | Multiple Sclerosis | Demyelinating Autoimmune Diseases, CNS | Autoimmune Diseases of the Nervous System | Demyelinating Diseases | Autoimmune Diseases

United States
University Hospital, Strasbourg, France

Suspended

Retrieval Practice and Schizophrenia

Schizophrenia | Episodic Memory Deficits

France
Washington University School of Medicine

Recruiting

Haploidentical Hematopoietic Stem Cell Transplantation With Ex Vivo TCR Alpha/Beta and CD19 Depletion in Pediatric Hematologic Malignancies

Pediatric Hematologic Malignancies

United States
Intrinsic LifeSciences, LLC
Boston Children's Hospital

Completed

Serum Hepcidin Immunoassay - Laboratory to Marketplace

Anemia, Iron Deficiency

United States
University of Alabama at Birmingham
ViraCor Laboratories

Withdrawn

COVID Vaccine Immunity in Kidney Transplant Recipients

End Stage Renal Disease | Kidney Transplant; Complications
Johns Hopkins University
National Cancer Institute (NCI); National Institutes of Health (NIH); ChiRhoClin...

Recruiting

The Cancer of the Pancreas Screening-5 CAPS5)Study (CAPS5)

Lynch Syndrome | Pancreas Cancer | Gene Mutation | Peutz-Jeghers Syndrome (PJS) | Germline Mutation Carrier

United States
University of Pennsylvania
National Cancer Institute (NCI); Alliance for Cancer Gene Therapy; OvaCure Fundation and other collaborators

Terminated

MOv19-BBz CAR T Cells in aFR Expressing Recurrent High Grade Serous Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Ovarian Cancer | Fallopian Tube Cancer | Primary Peritoneal Carcinoma

United States
daphne brockington

Unknown

Continuous Alloreactive T Cell Depletion and Regulatory T Cell Expansion for the Treatment of Steroid-refractory or Dependent Chronic GVHD (CARE)

Chronic GVHD After HCT for Cancer or Immune Disease

Canada
National Cancer Institute (NCI)

Terminated

Donor Stem Cell Transplant With No or Low-Intensity Chemotherapy Using Sirolimus and Treated Immune Cells to Treat Blood and Lymph Cancers

Lymphoma | Leukemia | Myeloproliferative Disorders | Myelodysplastic Syndrome | Multiple Myleoma

United States
Seagen Inc.
Genentech, Inc.

Completed

Trial to Define the Safety and Tolerability of SGN-40, Rituximab, and Gemcitabine in Patients With DLBCL

Lymphoma, Large B-Cell, Diffuse | Lymphoma, Non-Hodgkin

United States
Fondazione Italiana Linfomi - ETS

Recruiting

Prospective Biological Study to Evaluate the Persistence of COVID-19 Vaccine and Other Vaccines'-Induced Immune Responses in Follicular Lymphoma Patients Undergoing Frontline Induction Immuno-chemotherapy and Anti-CD20 Maintenance (FIL_FollVax22)

Follicular Lymphoma

Italy
Ronald Levy
National Institutes of Health (NIH)

Completed

Phase 1-2 of a CpG-Activated Whole Cell Vaccine Followed by Autologous Immunotransplant for MCL

Lymphoma, Mantle-Cell

United States
National Cancer Institute (NCI)

Completed

T-cells Expressing an Anti-SLAMF7 CAR for Treating Multiple Myeloma

Myeloma-Multiple | Myeloma, Plasma-Cell

United States
CARsgen Therapeutics Co., Ltd.
Fudan University; Peking University Cancer Hospital & Institute

Recruiting

Study to Evaluate the Efficacy, Safety and Pharmacokinetics of CT041 Autologous CAR T-cell Injection

Pancreatic Cancer | Gastric Adenocarcinoma | Gastroesophageal Junction Adenocarcinoma

China
National Institutes of Health Clinical Center (CC)
National Cancer Institute (NCI)

Terminated

Gene-Modified Lymphocytes, High-Dose Aldesleukin, and Vaccine Therapy in Treating Patients With Progressive or Recurrent Metastatic Cancer

Kidney Cancer | Unspecified Adult Solid Tumor, Protocol Specific | Melanoma (Skin)

United States
Iroko Pharmaceuticals, LLC

Withdrawn

Meloxicam SoluMatrix® Capsules vs Meloxicam Tablets to Treat Osteoarthritis Pain

Osteoarthritis
Memorial Sloan Kettering Cancer Center
Otsuka America Pharmaceutical; Ludwig Institute for Cancer Research

Completed

Busulfan, Melphalan, Fludarabine and T-Cell Depleted Allogeneic Hematopoietic Stem Cell Transplantation Followed by Post Transplantation Donor Lymphocyte Infusions

Multiple Myeloma

United States
Seattle Children's Hospital
Cures Within Reach

Unknown

Selecting Patient-Specific Biologically Targeted Therapy for Pediatric Patients With Refractory Or Recurrent Brain Tumors (SEED)

Recurrent Childhood Brain Tumor

United States
Karolinska Institutet

Unknown

Emotional and Non-emotional Regulation in Patients With Emotional Instability and ADHD

Attention Deficit Hyperactivity Disorder | Healthy Controls | Emotional Instability Personality Disorder (Borderline Personality Disorder)
M.D. Anderson Cancer Center
CLL Global Research Foundation Alliance

Withdrawn

Autologous ROR1R-CAR-T Cells for Chronic Lymphocytic Leukemia (CLL)

Leukemia
Centre Leon Berard
National Cancer Institute, France

Recruiting

Adapting Treatment to the Tumor Molecular Alterations for Patients With Advanced Solid Tumors: MyOwnSpecificTreatment (MOST plus)

Malignant Solid Neoplasms

France
M.D. Anderson Cancer Center

Withdrawn

Infusion of Expanded Cord Blood T Cells

Lymphoma | Leukemia | Stem Cell Transplantation | Pediatric Disorders
Hospital for Special Surgery, New York
Children's Healthcare of Atlanta; Campbell Clinic; Pediatric Orthopaedic Society... and other collaborators

Recruiting

Alpha-Defensin and Synovial Proteins to Improve Detection of Pediatric Septic Arthritis

Septic Arthritis | Joint Infection | Infection of Hip Joint (Disorder) | Infection of Shoulder Joint

United States
M.D. Anderson Cancer Center
Bristol-Myers Squibb; National Cancer Institute (NCI); Iovance Biotherapeutics

Active, not recruiting

Autologous Tumor Infiltrating Lymphocytes MDA-TIL in Treating Patients With Recurrent or Refractory Ovarian Cancer, Colorectal Cancer, or Pancreatic Ductal Adenocarcinoma

Malignant Solid Neoplasm | Metastatic Colorectal Adenocarcinoma | Stage IV Colorectal Cancer AJCC v8 | Stage IVA Colorectal Cancer AJCC v8 | Stage IVB Colorectal Cancer AJCC v8 | Stage IVC Colorectal Cancer AJCC v8 | Platinum-Resistant Ovarian Carcinoma | Metastatic Pancreatic Ductal Adenocarcinoma | Metastatic Ovarian Carcinoma and other conditions

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Fludarabine Phosphate, Radiation Therapy, and Rituximab in Treating Patients Who Are Undergoing Donor Stem Cell Transplant Followed by Rituximab for High-Risk Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

Chronic Lymphocytic Leukemia | Recurrent Small Lymphocytic Lymphoma | Prolymphocytic Leukemia | Refractory Chronic Lymphocytic Leukemia | Stage III Small Lymphocytic Lymphoma | Stage IV Small Lymphocytic Lymphoma | T-Cell Large Granular Lymphocyte Leukemia | Stage III Chronic Lymphocytic Leukemia | Stage...

United States, Denmark, Italy
National Cancer Institute (NCI)
AstraZeneca

Active, not recruiting

A Phase 2 Study of Cediranib in Combination With Olaparib in Advanced Solid Tumors

Metastatic Lung Non-Small Cell Carcinoma | Pancreatic Ductal Adenocarcinoma | Advanced Malignant Solid Neoplasm | Unresectable Pancreatic Carcinoma | Metastatic Pancreatic Adenocarcinoma | Stage III Pancreatic Cancer AJCC v6 and v7 | Stage IV Pancreatic Cancer AJCC v6 and v7 | Stage IIIA Lung Non-Small... and other conditions

United States, Canada
M.D. Anderson Cancer Center

Completed

Natural Killer (NK) Cell Adback After Allogeneic Stem Cell Transplant With Campath-IH Plus Chemorx for Patients With Lymphoid Malignancies

Lymphoma | Leukemia

United States
M.D. Anderson Cancer Center

Recruiting

Venetoclax to Improve Outcomes of Fractionated Busulfan Regimen in Patients With High-Risk AML and MDS

Acute Myeloid Leukemia | Chronic Myelomonocytic Leukemia | Myelodysplastic Syndrome

United States
University of Cincinnati

Completed

Randomized Trial for Mixed Acute Rejection

Graft Rejection

United States
University of Kansas Medical Center
National Cancer Institute (NCI); Iovance Biotherapeutics, Inc.

Recruiting

Lifileucel With Reduced Dose Fludarabine/Cyclophosphamide Lymphodepletion and Interleukin-2 for the Treatment of Patients With Unresectable or Metastatic Melanoma

Metastatic Melanoma | Unresectable Melanoma | Pathologic Stage IIIC Cutaneous Melanoma AJCC v8 | Clinical Stage IV Cutaneous Melanoma AJCC v8

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Engineered Donor Stem Cell Transplant in Treating Patients With Hematologic Malignancies

Acute Myeloid Leukemia | Recurrent Hodgkin Lymphoma | Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome | Chronic Myelomonocytic Leukemia | Acute Lymphoblastic Leukemia | Lymphoblastic Lymphoma | Myelodysplastic Syndrome | Plasma Cell Myeloma | Aplastic Anemia | Recurrent Non-Hodgkin... and other conditions

United States
Samara State Medical University

Recruiting

Clinical and Diagnostic Significance of Endothelial Dysfunction and Myocardial Contractility in Patients With AML

Endothelial Dysfunction | Cardiotoxicity | Acute Myeloid Leukemia, Adult

Russian Federation
University of Southern California
National Cancer Institute (NCI)

Not yet recruiting

A2-ESO-1 TCR-Engineered T Cells for Relapsed/Refractory Advanced or Metastatic NY-ESO-1 Overexpression Positive Triple Negative Breast Cancer

Triple Negative Breast Cancer

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Unknown

NK Cells in Cord Blood Transplantation

Recurrent Hodgkin Lymphoma | Refractory Hodgkin Lymphoma | Secondary Acute Myeloid Leukemia | Myelodysplastic Syndrome | Recurrent Acute Myeloid Leukemia | Recurrent Small Lymphocytic Lymphoma | Refractory Chronic Lymphocytic Leukemia | Recurrent Non-Hodgkin Lymphoma | Refractory Non-Hodgkin Lymphoma | Recurrent Acute Lymphoblastic Leukemia and other conditions

United States
QuantumLeap Healthcare Collaborative

Recruiting

I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer (I-SPY)

Breast Cancer | Breast Neoplasms | Breast Tumors | HER2-positive Breast Cancer | Angiosarcoma | Locally Advanced Breast Cancer | HER2-negative Breast Cancer | TNBC - Triple-Negative Breast Cancer | Hormone Receptor Positive Tumor | Hormone Receptor Negative Tumor | Early-stage Breast Cancer

United States
Julio Ramirez
University of Louisville

Terminated

Patients Response to Early Switch To Oral:Osteomyelitis Study (PRESTO:Osteo)

Osteomyelitis

United States
Monica Levy Andersen

Completed

Mother-caregivers of Children With Duchenne Muscular Dystrophy (DMDK)

Other Diseases or Conditions

Brazil
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Terminated

High-Dose Y-90-Ibritumomab Tiuxetan Added to Reduced-Intensity Allogeneic Stem Cell Transplant Regimen for Relapsed or Refractory Aggressive B-Cell Lymphoma

Recurrent Adult Diffuse Large Cell Lymphoma | Refractory B-Cell Non-Hodgkin Lymphoma | Recurrent B-Cell Non-Hodgkin Lymphoma | Refractory Diffuse Large B-Cell Lymphoma | Post-Transplant Lymphoproliferative Disorder | Recurrent Burkitt Lymphoma | Refractory Burkitt Lymphoma

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Phase IB Study to Evaluate the Safety of Selinexor (KPT-330) in Combination With Multiple Standard Chemotherapy or Immunotherapy Agents in Patients With Advanced Malignancies

Metastatic Renal Cell Carcinoma | Metastatic Lung Non-Small Cell Carcinoma | Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Metastatic Melanoma | Fallopian Tube Carcinoma | Advanced Malignant Solid Neoplasm | Stage III Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Stage III Renal... and other conditions

United States

Search clinical trials for: T-cell activation test using intracellular markers

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