Search clinical trials for: Tacrolimus (FK506)

Total 1109 results

The Second Hospital of Tangshan
Chinese PLA General Hospital

Recruiting

Investigation of Pain Incidence After FK506 Immunosuppressive Therapy in Liver Transplantation Patients

Liver Transplantation | Chronic Pain

China
Astellas Pharma Inc

Completed

An Open Study Assessing Bioavailability of a Modified Formulation of Tacrolimus in Kidney Transplant Recipients

Kidney Transplantation

Netherlands
Astellas Pharma S.A.S.

Completed

A Multicenter Study in Liver Transplant Patients Converted From Prograf® to Advagraf® During the First Post-transplantation Year (COBALT)

Liver Transplantation

France
Hordinsky, Maria K., MD

Completed

Effects of Ligands on Human Hair Follicles Grafted Onto SCID Mice

Alopecia

United States
Astellas Pharma Inc
Astellas Pharma Korea, Inc.

Completed

A Study to Evaluate the Efficacy and Safety of Tacrolimus in Korean Nephropathy Patients

IgA Nephropathy

Korea, Republic of
Astellas Pharma Inc

Completed

A Safety and Efficacy Study of Prograf in the Prevention of Erectile Dysfunction After Radical Prostatectomy

Erectile Dysfunction | Prostate Cancer

United States
Nanjing University School of Medicine

Terminated

The Efficacy and Safety of Tacrolimus in Treated Refractory Focal Segmental Glomerulosclerosis (FSGS)

FSGS

China
Astellas Pharma Korea, Inc.

Completed

Study to Evaluate the Safety and Efficacy of Advagraf vs Prograf in Kidney Transplantation Patients 1 Month After the Transplantation (AdProCISE)

de Novo Kidney Transplantation

Korea, Republic of
Astellas Pharma Inc

Completed

A Study to Evaluate the Safety and Efficacy of FK506E (MR4) in Patients Undergoing Primary Kidney Transplantation

Kidney Transplantation

Australia, France, United Kingdom, Germany, Spain, Argentina, South Africa, Switzerland, Canada, Finland, Greece, Netherlands, Brazil, Belgium, Poland, Hungary, Czech Republic, Austria, Ireland, Italy, Mexico, Norway, Sweden
Indiana University
Food and Drug Administration (FDA)

Completed

Effects of Altered Formulation on the Bioequivalence of Tacrolimus in Healthy Female and Male Volunteeers (ASDBioequiv)

Bioequivalence

United States
Guangdong Provincial People's Hospital

Unknown

Tacrolimus Combined With Entecavir on HBV Associated Glomerulonephritis(HBV-GN) (TOHBVGN)

Hepatitis B Virus Associated Nephrotic Syndrome

China
Astellas Pharma Inc

Completed

A Study to Evaluate the Drug Interaction of ASP015K and Tacrolimus

Healthy | Pharmacokinetics of ASP015K and Tacrolimus

United States
Astellas Pharma S.A.S.

Completed

A Study of Renal Transplant Patients Converted From the Twice Per Day Form of Tacrolimus (Prograf®) to the Once Per Day Form (Advagraf®) (OPALE)

Renal Transplantation

France
Astellas Pharma Inc

Completed

Pharmacokinetic Interaction Study to Assess the Effect of ASP015K on Tacrolimus in Healthy Volunteers

Healthy Subjects | Drug Interactions | Pharmacokinetics of ASP015K

United States
Kasr El Aini Hospital

Completed

Efficiency of Fractional-Laser Resurfacing Followed by Topical Tacrolimus 0.03% Cream vs Tacrolimus Alone in Vitiligo

Stable Vitiligo
Astellas Pharma Inc
Astellas Pharma Taiwan, Inc.

Completed

A Randomized Study to Assess the Safety and Efficacy of Prograf vs Prograf-XL in de Novo Kidney Transplant Recipients

Kidney Transplantation | Transplantation Immunology | Host vs Graft Reaction

Taiwan
Peking University Third Hospital

Completed

Evaluation of 0.05% CsA and 0.1% FK506 Eye Drops in Ocular GVHD Treatment

Graft Versus Host Disease in Eye

China
Rockefeller University

Completed

Immunotherapy of the Paraneoplastic Syndromes

Paraneoplastic Syndromes

United States
East Carolina University
Astellas Pharma US, Inc.

Completed

Optima: Optimizing Prograf Therapy in Maintenance Allografts II (OPTIMAII)

Kidney Transplantation

United States
Astellas Pharma Inc
Astellas Pharma China, Inc.

Terminated

A Study to Compare the Efficacy and Safety of Tacrolimus Capsules With Leflunomide Tablets in Lupus Nephritis Patients

Lupus Nephritis

China
Astellas Pharma Inc

Completed

To Compare the Efficacy and Safety of a Therapy of Tacrolimus With Sirolimus or MMF in Kidney Transplantation. (RESTORE)

Kidney Transplantation

Belgium, France, Germany, Spain, Australia, Italy, Austria, Romania, United Kingdom, Poland, Hungary, Sweden, Netherlands, Czech Republic
University of Pittsburgh

Terminated

Pharmacokinetics of Sirolimus and Tacrolimus in Liver Transplant Recipients With Tacrolimus Toxicity (Sirolimus)

Hypertension
Astellas Pharma Inc

Completed

Comparison of Two Tacrolimus Based Immunosuppressive Regimens in Recipients Receiving Marginal Donor Kidneys (TIGRE)

KIDNEY TRANSPLANTATION

Italy
Washington University School of Medicine

Withdrawn

Enhancement of Functional Recovery After Peripheral Nerve Injury With Tacrolimus

Peripheral Nerve Injury
Astellas Pharma Inc

Completed

A Conversion Study to Assess Safety and Efficacy of a MR4 Based Immunosuppressive Regimen in Stable Kidney Recipients

Transplantation

Netherlands, Spain, Germany, United Kingdom, Poland, France
Astellas Pharma Inc

Completed

Comparative Study of Modified Release (MR) Tacrolimus/Mycophenolate Mofetil (MMF) in de Novo Kidney Transplant Recipients

Kidney Transplantation

United States, Canada, Brazil
Astellas Pharma China, Inc.

Completed

Clinical Outcome of Delayed or Standard Prograf Together With Induction Therapy Followed by Conversion to Advagraf in Donation After Cardiac (or Circulatory) Death (DCD) Kidney Transplant Recipients

Kidney Transplant

China
Sun Yat-sen University

Completed

Prospective, Randomized, Multicenter, Control Study to Assess the Efficacy and Safety of Tacrolimus in Induction and Maintenance Phase Treatment in Lupus Nephritis

Kidney Diseases | Lupus Nephritis | Tacrolimus | Induction Phase | Maintenance Phase

China
Institute for Clinical and Experimental Medicine
Sahlgrenska University Hospital, Sweden; University Hospital, Motol

Recruiting

Uterus Transplantation From Live Donors and From Deceased Donors - Clinical Study (UTxLD/DBD)

Infertility, Female | Mayer Rokitansky Kuster Hauser Syndrome | Absolute Uterine Factor Infertility | Mullerian Aplasia | Uterus; Absence, Congenital | Uterus Absence, Acquired

Czechia
Astellas Pharma Europe Ltd.

Terminated

To Validate an Analytical Method to Measure Concentration of Tacrolimus in Blood Taken From Finger Pricks

Validation | Dried Blood Spot | Transplant Patients

France, United Kingdom
Astellas Pharma Inc

Completed

Comparing Efficacy and Safety of Tacrolimus With Steroids or Monoclonal Anti-IL2R Antibody in Hepatitis C Virus (HCV) Positive Liver Transplant Patients (CHASE)

Liver Transplantation | Hepatitis C

Italy, France, Germany, Sweden, United Kingdom, Poland, Spain, Czech Republic
Astellas Pharma Inc
Astellas Pharma Korea, Inc.

Completed

Study to Evaluate the Efficacy of Tacrolimus in Rheumatoid Arthritis Patients Shown Unsuccessful Response to Methotrexate

Rheumatoid Arthritis

Korea, Republic of
Astellas Pharma Inc
Astellas Pharma Korea, Inc.

Completed

A Study to Evaluate the Efficacy of Tacrolimus in Rheumatoid Arthritis Patients Shown Unsuccessful Response to Methotrexate

Rheumatoid Arthritis

Korea, Republic of
Astellas Pharma Inc

Completed

A Conversion Study to Assess Safety and Efficacy of a MR4 Based Immunosuppressive Regimen in Stable Liver Recipients

Transplantation

France, Spain, Germany, United Kingdom, Ireland, Poland
Nanjing University School of Medicine

Completed

Study to Assess the Efficacy and Safety of FK506 Combined With Mycophenolate Mofetil (MMF) in Lupus Nephritis (III/IV/V)

Lupus Nephritis

China
Astellas Pharma Inc

Completed

Comparing Efficacy and Safety of Steroid Withdrawal With Tacrolimus and MMF With Induction in Children After Kidney Transplantation (TWIST)

Kidney Transplantation

Belgium, Italy, Taiwan, France, South Africa, Turkey, Germany, United Kingdom, Hungary, Czech Republic, Romania, Sweden, Poland, Israel
Baylor College of Medicine
The Methodist Hospital Research Institute; Center for Cell and Gene Therapy...

Completed

Conditioning Regimen for Allogeneic Hematopoietic Stem Cell Transplantation of Patients With Hematological Diseases

Hematologic Malignancy

United States
Johns Hopkins University

Recruiting

Uterus Transplantation to Treat Infertility (OPRTUNTI)

Uterine Factor Infertility

United States
Astellas Pharma Europe Ltd.

Completed

Global, Multicentre, Non Interventional Advagraf Conversion Registry in Kidney Transplant Patients (CHORUS)

Kidney Transplantation

Australia, Austria, Belgium, Canada, Czechia, France, Germany, Greece, Hong Kong, Hungary, Italy, Japan, Korea, Republic of, Malaysia, Netherlands, Philippines, Poland, Portugal, Romania, Serbia, Spain, Taiwan, Thailand, United Kingdom, Vietna...
Astellas Pharma Inc

Completed

Comparison Study Between Protopic (Tacrolimus Ointment) and Elidel (Pimecrolimus Cream) in Treating Pediatric Patients With Atopic Dermatitis

Dermatitis, Atopic

United States
Zhi-Hong Liu, M.D.
The First Affiliated Hospital with Nanjing Medical University; China Medical... and other collaborators

Completed

Assess the Efficacy and Safety of Multi-target Therapy in Lupus Nephritis

Lupus Nephritis

China
Zhi-Hong Liu, M.D.

Completed

Treatment of Idiopathic Membranous Nephropathy With Tripterygium Wilfordii Plus Steroid vs Tacrolimus Plus Steroid

Idiopathic Membranous Nephropathy

China
Assiut University

Unknown

The Effect of Fractional Co2 Laser Either With Tacrolimus, Calcipotriol or NB-UVB in Stable Generalized Vitiligo

Vitiligo Vulgaris
Astellas Pharma Inc
Astellas Pharma Canada, Inc.

Completed

Comparison of Extended Release Tacrolimus (Advagraf) and Cyclosporine A Microemulsion on Renal Function in Healthy Volunteers

Healthy

Canada
Astellas Pharma Inc
Astellas Pharma Canada, Inc.

Completed

Tacrolimus as Secondary Intervention vs. Continuation of Cyclosporine in Renal Transplant Patients With Chronic Renal Allograft Failure (CRAF)

Renal Transplantation | Chronic Renal Allograft Failure

Canada
Fuzhou General Hospital

Unknown

Mesenchymal Stem Cell Transplantation in the Treatment of Chronic Allograft Nephropathy

Kidney Transplant | Chronic Allograft Nephropathy

China
Baylor College of Medicine
The Methodist Hospital Research Institute

Terminated

Stem Cell Transplant for Hematologic Diseases (HIMSUM)

Hematologic Malignancies

United States
Astellas Pharma Inc

Completed

Comparison Study Between Protopic (Tacrolimus Ointment) and Elidel (Pimecrolimus Cream) in Pediatric Patients With Mild Atopic Dermatitis

Dermatitis, Atopic

United States
Astellas Pharma Inc

Completed

A Comparison Study Between Protopic (Tacrolimus) Ointment and Elidel (Pimecrolimus) Cream in Treating Subjects With Atopic Dermatitis

Dermatitis, Atopic

United States, Canada
Pavly Moawd

Completed

Comparing Effect of Topical Tacrolimus 0.03% Versus Cyclosporine 0.05% in Dry Eyes of Secondary Sjogren Syndrome

Dry Eye | Sjogren Syndrome

Egypt

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