Search clinical trials for: Temodar and SCH 66336

Total 2115 results

Duke University
Schering-Plough

Completed

PH I Addition of Farnesyl Transferase Inhibitor to Temozolomide for Pts w Gr 3 & 4 Malignant Gliomas

Glioblastoma | Gliosarcoma | Anaplastic Astrocytoma

United States
Merck Sharp & Dohme LLC

Completed

SCH 52365 Phase II Clinical Study: A Study on the Efficacy and Safety of Monotherapy With SCH 52365 in Patients With First Relapsed Anaplastic Astrocytoma (Study P03745)

Astrocytoma
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Lonafarnib and Temozolomide in Treating Patients With Glioblastoma Multiforme That Is Recurrent or Did Not Respond to Previous Treatment With Temozolomide

Recurrent Glioblastoma | Recurrent Gliosarcoma | Malignant Supratentorial Neoplasm

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI)

Completed

SCH 66336 in Treating Children With Recurrent or Progressive Brain Tumors

Brain and Central Nervous System Tumors

United States
Merck Sharp & Dohme LLC

Terminated

Study of Lonafarnib Versus Placebo in Subjects With Either Myelodysplastic Syndrome (MDS) or Chronic Myelomonocytic Leukemia (CMML) (Study P02978AM3)(TERMINATED)

Myelodysplastic Syndromes | Leukemia, Myelomonocytic, Chronic | Myelodysplasia | Myelomonocytic
Merck Sharp & Dohme LLC

Completed

Standard Temodal (Temozolomide) Regimen Versus Standard Regimen Plus Early Postsurgery Temodal for Newly Diagnosed Glioblastoma Multiforme (Study P05572)

Glioblastoma
Merck Sharp & Dohme LLC

Completed

Temozolomide Phase II Clinical Study in Patients With Newly Diagnosed Glioblastoma Multiforme (Study P04661)(COMPLETED)

Glioblastoma
Merck Sharp & Dohme LLC

Completed

Temozolomide in Concomitant Radiochemotherapy Followed by Sequential Temozolomide Chemotherapy - Observational Program (Study P04816)

Glioblastoma
Northwestern University
GlaxoSmithKline; National Comprehensive Cancer Network; Robert H. Lurie Cancer...

Completed

Temozolomide and Pazopanib Hydrochloride in Treating Patients With Advanced Pancreatic Neuroendocrine Tumors That Cannot Be Removed By Surgery

Recurrent Islet Cell Carcinoma | Pancreatic Alpha Cell Carcinoma | Pancreatic Beta Islet Cell Carcinoma | Pancreatic Delta Cell Carcinoma | Pancreatic G-cell Carcinoma

United States
Merck Sharp & Dohme LLC

Completed

Efficacy and Safety of Temodal vs Semustine in Subjects With Recurrent Glioblastoma or Anaplastic Astrocytoma (Study P03644)

Glioblastoma | Astrocytoma
Merck Sharp & Dohme LLC

Completed

Temodal (Temozolomide) Post Marketing Surveillance Protocol (Study P05557AM2)

Glioma | Glioblastoma | Astrocytoma
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Withdrawn

SCH 66336 Before Surgery in Treating Patients With Colorectal Cancer That Has Metastasized to the Liver

Colorectal Cancer | Metastatic Cancer
Merck Sharp & Dohme LLC
European Organisation for Research and Treatment of Cancer - EORTC

Completed

Temozolomide Versus Dacarbazine in Stage IV Metastatic Melanoma (Study P03267)

Melanoma
Merck Sharp & Dohme LLC

Completed

Post Marketing Surveillance: Newly Diagnosed Glioblastoma Multiforme Treated With Radiotherapy/Temozolomide and Adjuvant Temozolomide (Study P04739)

Glioblastoma
National Cancer Institute (NCI)

Completed

Tipifarnib, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme or Gliosarcoma

Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma

United States
Mayo Clinic
National Cancer Institute (NCI)

Completed

Individualized Temozolomide in Treating Patients With Stage IV Melanoma That Cannot Be Removed By Surgery

Recurrent Melanoma | Stage IV Melanoma

United States
National Cancer Institute (NCI)

Terminated

Methoxyamine and Temozolomide in Treating Patients With Recurrent Glioblastoma

Adult Brain Glioblastoma

United States
IFOM ETS - The AIRC Institute of Molecular Oncology

Active, not recruiting

Pembrolizumab in MMR-Proficient Metastatic Colorectal Cancer Pharmacologically Primed to Trigger Hypermutation Status (ARETHUSA)

Colorectal Neoplasms | Microsatellite Instability

Italy
M.D. Anderson Cancer Center
National Cancer Institute (NCI); Schering-Plough

Terminated

4-HPR and FTI in Head and Neck Squamous Cell Carcinoma (HNSCC)

Head and Neck Cancer

United States
Bernardino Clavo, MD, PhD
Instituto de Salud Carlos III; Instituto Tecnologico Servicios Sanitarios,... and other collaborators

Terminated

FMISO-PET in Brain Tumors and SCS Effect (FMISOPETSCS)

Malignant Glioma

Spain
Huashan Hospital

Unknown

A Prospective Cohort to Study the Effect of Temozolomide on IDH Mutational Low Grade Gliomas

Astrocytoma | Oligoastrocytoma | Oligodendroglioma

China
Bruno C. Medeiros
Schering-Plough

Completed

Phase 2 Study of Temozolomide to Treat Poor Risk / Refractory Acute Myeloid Leukemia

Leukemia, Myeloid

United States
Marmara University
Schering-Plough

Completed

Efficacy of Protracted Temozolomide in Patients With Progressive High Grade Glioma

Glioblastoma | Astrocytoma | Oligodendroglioma | Brain Tumor, Recurrent

Turkey
Assistance Publique - Hôpitaux de Paris
Association de Neuro-Oncologues d'Expression Francaise

Completed

Temozolomide in Elderly Patients With KPS < 70 (TAG)

Glioblastoma | Primary Brain Tumor

France
National Cancer Institute (NCI)

Completed

Cilengitide, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma

United States
Merck Sharp & Dohme LLC

Completed

Temozolomide All-Case-Registered Surveillance (Designated Drug Use Investigation)(Study P05062)

Glioma | Astrocytoma
National Cancer Institute (NCI)

Completed

ABT-888 and Temozolomide in Treating Young Patients With Recurrent or Refractory CNS Tumors

Recurrent Childhood Medulloblastoma | Recurrent Childhood Ependymoma | Childhood Atypical Teratoid/Rhabdoid Tumor | Childhood Choroid Plexus Tumor | Childhood Craniopharyngioma | Childhood Ependymoblastoma | Childhood Grade I Meningioma | Childhood Grade II Meningioma | Childhood Grade III Meningioma | Childhood High-grade Cerebellar Astrocytoma and other conditions

United States
Jonsson Comprehensive Cancer Center
Schering-Plough

Completed

Temozolomide in Treating Patients With Solid Tumors That Have Spread to the Brain

Metastatic Cancer

United States
National Cancer Institute (NCI)

Completed

Temozolomide and O6-Benzylguanine in Treating Children With Recurrent Brain Tumors

Recurrent Childhood Medulloblastoma | Recurrent Childhood Ependymoma | Childhood Choroid Plexus Tumor | Childhood Craniopharyngioma | Childhood Ependymoblastoma | Childhood Grade I Meningioma | Childhood Grade II Meningioma | Childhood Grade III Meningioma | Childhood High-grade Cerebellar Astrocytoma | Childhood High-grade Cerebral Astrocytoma and other conditions

United States
Mashhad University of Medical Sciences

Unknown

Efficacy of Two Temozolomide Regimens in Adjuvant Treatment of Patients With Brain High Grade Glioma

Glioblastoma Multiforme of Brain | Anaplastic Astrocytoma of Brain

Iran, Islamic Republic of
Cliniques universitaires Saint-Luc- Université...

Unknown

Prolonged Adjuvant Temozolomide vs "Stop & Go" in Glioblastoma Patients (PATSGO)

Glioblastoma

Belgium
Merck Sharp & Dohme LLC

Terminated

Study of Maintenance Temozolomide Versus Observation in Stable or Responding Stage III/IV Non-Small Cell Lung Cancer Patients (Study P05146)

Adenocarcinoma | Carcinoma, Non-Small-Cell Lung | Carcinoma, Squamous Cell | Carcinoma, Large Cell
National Cancer Institute (NCI)

Completed

Erlotinib and Temozolomide in Treating Young Patients With Recurrent or Refractory Solid Tumors

Recurrent Childhood Medulloblastoma | Recurrent Childhood Ependymoma | Recurrent Neuroblastoma | Recurrent Osteosarcoma | Recurrent Childhood Rhabdomyosarcoma | Previously Treated Childhood Rhabdomyosarcoma | Recurrent Childhood Soft Tissue Sarcoma | Recurrent Childhood Malignant Germ Cell Tumor | Recurrent... and other conditions

United States
The University of Texas Health Science Center at...
National Cancer Institute (NCI); Cancer Therapy and Research Center, Texas

Completed

Chemotherapy in Treating Patients With Advanced Solid Tumors

Unspecified Adult Solid Tumor, Protocol Specific

United States
National Cancer Institute (NCI)

Completed

Vorinostat and Temozolomide in Treating Young Patients With Relapsed or Refractory Primary Brain Tumors or Spinal Cord Tumors

Recurrent Childhood Medulloblastoma | Recurrent Childhood Ependymoma | Childhood Atypical Teratoid/Rhabdoid Tumor | Extra-adrenal Paraganglioma | Childhood Choroid Plexus Tumor | Childhood Craniopharyngioma | Childhood Ependymoblastoma | Childhood Grade I Meningioma | Childhood Grade II Meningioma | Childhood... and other conditions

United States, Canada
National Cancer Institute (NCI)

Completed

Erlotinib and Temozolomide With Radiation Therapy in Treating Patients With Glioblastoma Multiforme or Other Brain Tumors

Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma

United States
Valent Technologies, LLC

Recruiting

Flavored, Oral Irinotecan VAL-413 (Orotecan®) Given With Temozolomide for Treatment of Recurrent Pediatric Solid Tumors

Ewing Sarcoma | Medulloblastoma | Neuroblastoma | Solid Tumors | Rhabdomyosarcoma | Hepatoblastoma

United States
Instituto Nacional de Cancerologia de Mexico

Completed

Whole Brain Radiotherapy With or Without Temozolomide at Daily Fixed-dose for Brain Metastases Treatment

Brain Neoplasms

Mexico
Boston Children's Hospital
Dana-Farber Cancer Institute; Brigham and Women's Hospital; Schering-Plough

Completed

A Study of Zoledronic Acid, Pravastatin, and Lonafarnib for Patients With Progeria

Progeria | Hutchinson-Gilford Syndrome

United States
Xinhua Hospital, Shanghai Jiao Tong University...

Unknown

Radiation Therapy and Combination Chemotherapy for Medulloblastoma

Medulloblastoma

China
Merck Sharp & Dohme LLC

Terminated

A Study to Evaluate the Safety, Tolerability, and Activity of Lonafarnib and Docetaxel (Study P04467AM1)(TERMINATED)

Breast Cancer | Gastric Cancer | Ovarian Cancer | Lung Cancer | Prostate Cancer
Merck Sharp & Dohme LLC

Terminated

Phase 2 Study of Temozolomide in Pre-Selected Advanced Aerodigestive Tract Cancers (Study P04273AM2)(TERMINATED)

Carcinoma, Non-Small-Cell Lung | Colorectal Neoplasm | Esophageal Neoplasm | Head and Neck Neoplasm
Lawrence Recht
National Cancer Institute (NCI)

Completed

Plerixafor After Radiation Therapy and Temozolomide in Treating Patients With Newly Diagnosed High Grade Glioma

Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Adult Mixed Glioma | Adult Ependymoblastoma | Adult Medulloblastoma | Adult Pineoblastoma | Adult Supratentorial Primitive Neuroectodermal Tumor (PNET) | Adult Oligodendroglial Tumors

United States
Kari Kendra

Recruiting

Natural Killer Cell Therapy (UD TGFbetai NK Cells) and Temozolomide for the Treatment of Stage IV Melanoma Metastatic to the Brain

Metastatic Melanoma | Clinical Stage IV Cutaneous Melanoma AJCC v8 | Pathologic Stage IV Cutaneous Melanoma AJCC v8 | Metastatic Malignant Neoplasm in the Brain

United States
Milton S. Hershey Medical Center

Completed

High Dose Interleukin-2 Followed by Intermittent Low Dose Temozolomide in Patients With Melanoma

Malignant Melanoma

United States
NRG Oncology
National Cancer Institute (NCI); Radiation Therapy Oncology Group

Active, not recruiting

Dose-Escalated Photon IMRT or Proton Beam Radiation Therapy Versus Standard-Dose Radiation Therapy and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma

Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma

United States, Canada
University of Nebraska
National Cancer Institute (NCI)

Terminated

Temozolomide and Ascorbic Acid in Treating Patients With Recurrent High-Grade Glioma

Glioblastoma | Gliosarcoma | Anaplastic Oligoastrocytoma | Anaplastic Astrocytoma | Anaplastic Oligodendroglioma

United States
National Cancer Institute (NCI)

Completed

Temozolomide and Thalidomide in Treating Patients With Brain Metastases Secondary to Melanoma

Recurrent Melanoma | Stage IV Melanoma | Tumors Metastatic to Brain

United States
Ohio State University Comprehensive Cancer Center

Completed

Temozolomide and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme or Anaplastic Astrocytoma

Glioblastoma Multiforme/Anaplastic Astrocytoma

United States
Merck Sharp & Dohme LLC

Completed

Anastrozole Plus Lonafarnib (SCH 66336) or Plus Placebo for the Treatment of Advanced Breast Cancer (P03480)

Breast Cancer

Search clinical trials for: Temodar and SCH 66336

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