Search clinical trials for: Temodar (Temozolomide)

Total 941 results

Jonsson Comprehensive Cancer Center
Schering-Plough

Completed

Temozolomide in Treating Patients With Solid Tumors That Have Spread to the Brain

Metastatic Cancer

United States
The University of Texas Health Science Center at...
National Cancer Institute (NCI); Cancer Therapy and Research Center, Texas

Completed

Chemotherapy in Treating Patients With Advanced Solid Tumors

Unspecified Adult Solid Tumor, Protocol Specific

United States
Huashan Hospital

Unknown

A Prospective Cohort to Study the Effect of Temozolomide on IDH Mutational Low Grade Gliomas

Astrocytoma | Oligoastrocytoma | Oligodendroglioma

China
Bruno C. Medeiros
Schering-Plough

Completed

Phase 2 Study of Temozolomide to Treat Poor Risk / Refractory Acute Myeloid Leukemia

Leukemia, Myeloid

United States
Marmara University
Schering-Plough

Completed

Efficacy of Protracted Temozolomide in Patients With Progressive High Grade Glioma

Glioblastoma | Astrocytoma | Oligodendroglioma | Brain Tumor, Recurrent

Turkey
Assistance Publique - Hôpitaux de Paris
Association de Neuro-Oncologues d'Expression Francaise

Completed

Temozolomide in Elderly Patients With KPS < 70 (TAG)

Glioblastoma | Primary Brain Tumor

France
Cliniques universitaires Saint-Luc- Université...

Unknown

Prolonged Adjuvant Temozolomide vs "Stop & Go" in Glioblastoma Patients (PATSGO)

Glioblastoma

Belgium
Northwestern University
GlaxoSmithKline; National Comprehensive Cancer Network; Robert H. Lurie Cancer...

Completed

Temozolomide and Pazopanib Hydrochloride in Treating Patients With Advanced Pancreatic Neuroendocrine Tumors That Cannot Be Removed By Surgery

Recurrent Islet Cell Carcinoma | Pancreatic Alpha Cell Carcinoma | Pancreatic Beta Islet Cell Carcinoma | Pancreatic Delta Cell Carcinoma | Pancreatic G-cell Carcinoma

United States
Merck Sharp & Dohme LLC

Completed

SCH 52365 Phase II Clinical Study: A Study on the Efficacy and Safety of Monotherapy With SCH 52365 in Patients With First Relapsed Anaplastic Astrocytoma (Study P03745)

Astrocytoma
Ohio State University Comprehensive Cancer Center

Completed

Temozolomide and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme or Anaplastic Astrocytoma

Glioblastoma Multiforme/Anaplastic Astrocytoma

United States
Mashhad University of Medical Sciences

Unknown

Efficacy of Two Temozolomide Regimens in Adjuvant Treatment of Patients With Brain High Grade Glioma

Glioblastoma Multiforme of Brain | Anaplastic Astrocytoma of Brain

Iran, Islamic Republic of
European Organisation for Research and Treatment...
Merck Sharp & Dohme LLC; Medical Research Council; NCIC Clinical Trials Group; Radiation...

Active, not recruiting

Phase III Trial of Anaplastic Glioma Without 1p/19q Loss of Heterozygosity (LOH) (CATNON)

Brain and Central Nervous System Tumors

Netherlands, United Kingdom, Australia, United States, Belgium, France, Germany, Canada, Israel, Switzerland, Italy, Spain
National Cancer Institute (NCI)

Completed

Tipifarnib, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme or Gliosarcoma

Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma

United States
Instituto Nacional de Cancerologia de Mexico

Completed

Whole Brain Radiotherapy With or Without Temozolomide at Daily Fixed-dose for Brain Metastases Treatment

Brain Neoplasms

Mexico
Valent Technologies, LLC

Recruiting

Flavored, Oral Irinotecan VAL-413 (Orotecan®) Given With Temozolomide for Treatment of Recurrent Pediatric Solid Tumors

Ewing Sarcoma | Medulloblastoma | Neuroblastoma | Solid Tumors | Rhabdomyosarcoma | Hepatoblastoma

United States
Mayo Clinic
National Cancer Institute (NCI)

Completed

Individualized Temozolomide in Treating Patients With Stage IV Melanoma That Cannot Be Removed By Surgery

Recurrent Melanoma | Stage IV Melanoma

United States
AbbVie (prior sponsor, Abbott)

Completed

A Study Evaluating Efficacy of ABT-888 in Combination With Temozolomide in Metastatic Melanoma

Melanoma | Skin Cancer | Metastatic Melanoma
Merck Sharp & Dohme LLC

Completed

Standard Temodal (Temozolomide) Regimen Versus Standard Regimen Plus Early Postsurgery Temodal for Newly Diagnosed Glioblastoma Multiforme (Study P05572)

Glioblastoma
Merck Sharp & Dohme LLC

Completed

Temozolomide Phase II Clinical Study in Patients With Newly Diagnosed Glioblastoma Multiforme (Study P04661)(COMPLETED)

Glioblastoma
Merck Sharp & Dohme LLC

Completed

Temozolomide in Concomitant Radiochemotherapy Followed by Sequential Temozolomide Chemotherapy - Observational Program (Study P04816)

Glioblastoma
Merck Sharp & Dohme LLC

Completed

Temozolomide All-Case-Registered Surveillance (Designated Drug Use Investigation)(Study P05062)

Glioma | Astrocytoma
Merck Sharp & Dohme LLC

Completed

Efficacy and Safety of Temodal vs Semustine in Subjects With Recurrent Glioblastoma or Anaplastic Astrocytoma (Study P03644)

Glioblastoma | Astrocytoma
Xinhua Hospital, Shanghai Jiao Tong University...

Unknown

Radiation Therapy and Combination Chemotherapy for Medulloblastoma

Medulloblastoma

China
Merck Sharp & Dohme LLC

Completed

Temodal (Temozolomide) Post Marketing Surveillance Protocol (Study P05557AM2)

Glioma | Glioblastoma | Astrocytoma
Jong Hoon Kim

Unknown

Efficacy Study of Radiotherapy Alone Versus CCRT With Temozolomide in Grade III Gliomas Without 1p/19q Codeletion

Anaplastic Glioma of Brain | Loss of Chromosomes 1p/19q

Korea, Republic of
IFOM ETS - The AIRC Institute of Molecular Oncology

Active, not recruiting

Pembrolizumab in MMR-Proficient Metastatic Colorectal Cancer Pharmacologically Primed to Trigger Hypermutation Status (ARETHUSA)

Colorectal Neoplasms | Microsatellite Instability

Italy
Merck Sharp & Dohme LLC
European Organisation for Research and Treatment of Cancer - EORTC

Completed

Temozolomide Versus Dacarbazine in Stage IV Metastatic Melanoma (Study P03267)

Melanoma
Steven E. Coutre
Merck Sharp & Dohme LLC

Completed

Temozolomide Plus Vorinostat in Relapse/Refractory Acute Myeloid Leukemia (AML)

Acute Myeloid Leukemia With 11q23-abnormality in Relapse

United States
National Cancer Institute (NCI)

Completed

Cilengitide, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma

United States
University of California, San Francisco
National Cancer Institute (NCI)

Completed

Temozolomide in Treating Patients With Recurrent High-Grade Glioma

Recurrent Central Nervous System Neoplasm

United States
Merck Sharp & Dohme LLC

Completed

Post Marketing Surveillance: Newly Diagnosed Glioblastoma Multiforme Treated With Radiotherapy/Temozolomide and Adjuvant Temozolomide (Study P04739)

Glioblastoma
National Cancer Institute (NCI)

Completed

ABT-888 and Temozolomide in Treating Young Patients With Recurrent or Refractory CNS Tumors

Recurrent Childhood Medulloblastoma | Recurrent Childhood Ependymoma | Childhood Atypical Teratoid/Rhabdoid Tumor | Childhood Choroid Plexus Tumor | Childhood Craniopharyngioma | Childhood Ependymoblastoma | Childhood Grade I Meningioma | Childhood Grade II Meningioma | Childhood Grade III Meningioma | Childhood High-grade Cerebellar Astrocytoma and other conditions

United States
Bradmer Pharmaceuticals Inc.

Terminated

Glioblastoma Multiforme (GBM) Locoregional Agent Survival Study - Anti-tenascin Radiolabeled Antibody Therapy (Glass-Art)

Glioblastoma Multiforme
Milton S. Hershey Medical Center

Completed

High Dose Interleukin-2 Followed by Intermittent Low Dose Temozolomide in Patients With Melanoma

Malignant Melanoma

United States
University of California, San Francisco

Completed

Temozolomide in Treating Patients With Low-Grade Glioma

CNS Tumor, Adult

United States
The Cleveland Clinic
National Cancer Institute (NCI)

Completed

Temozolomide in Treating Patients With Newly Diagnosed Anaplastic Oligodendroglioma or Mixed Oligoastrocytoma

Brain Tumor | Central Nervous System Tumors

United States
University of Alabama at Birmingham
Integrated Therapeutics Group

Completed

Phase II Study of Gamma Knife Radiosurgery and Temozolomide for Brain Metastases (RAD0102)

Cancer | Brain Metastases

United States
M.D. Anderson Cancer Center
Cortice Biosciences, Inc.

Terminated

A Phase I Study of TPI 287 - Temozolomide Combination in Melanoma

Melanoma

United States
National Cancer Institute (NCI)

Completed

Temozolomide and O6-Benzylguanine in Treating Children With Recurrent Brain Tumors

Recurrent Childhood Medulloblastoma | Recurrent Childhood Ependymoma | Childhood Choroid Plexus Tumor | Childhood Craniopharyngioma | Childhood Ependymoblastoma | Childhood Grade I Meningioma | Childhood Grade II Meningioma | Childhood Grade III Meningioma | Childhood High-grade Cerebellar Astrocytoma | Childhood High-grade Cerebral Astrocytoma and other conditions

United States
Stanford University

Completed

Phase 1-2 of Temozolomide and Hypofractionated Radiotherapy in Tx of Supratentorial Glioblastoma Multiform (Tx-Treatment)

Glioblastoma | Glioblastoma Multiforme | Cancer of Brain and Nervous System

United States
Xinhua Hospital, Shanghai Jiao Tong University...

Unknown

Nimotuzumab in Combination With Radio-chemotherapy for the Treatment of Brainstem Tumor in Children

Childhood Brain Stem Neoplasm

China
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Temozolomide in Treating Young Patients With Refractory or Recurrent Leukemia

Leukemia

Canada, United States
Northwestern University
Vion Pharmaceuticals

Terminated

VNP40101M and Temozolomide in Treating Patients With Progressive or Relapsed Malignant Glioma

Brain and Central Nervous System Tumors

United States
University of Sydney
Cooperative Trials Group for Neuro-Oncology

Active, not recruiting

Nivolumab and Temozolomide Versus Temozolomide Alone in Newly Diagnosed Elderly Patients With GBM (NUTMEG)

Glioblastoma Multiforme

United States, Australia
Duke University
National Institutes of Health (NIH); Keryx / AOI Pharmaceuticals, Inc.

Completed

Ph. II Temozolomide + O6-BG in Treatment of Pts w Temozolomide-Resistant Malignant Glioma

Glioblastoma Multiforme | Anaplastic Glioma

United States
Sidney Kimmel Cancer Center at Thomas Jefferson...
Bayer

Completed

Combination of Sorafenib and Radiation for Brain Metastases and Primary Brain Tumors

Brain Metastases | Primary Brain Tumors

United States
Duke University
Pfizer

Completed

Ph. II Treatment of Adults w Primary Malignant Glioma w Irinotecan + Temozolomide

Glioblastoma

United States
National Cancer Institute (NCI)

Completed

Erlotinib and Temozolomide in Treating Young Patients With Recurrent or Refractory Solid Tumors

Recurrent Childhood Medulloblastoma | Recurrent Childhood Ependymoma | Recurrent Neuroblastoma | Recurrent Osteosarcoma | Recurrent Childhood Rhabdomyosarcoma | Previously Treated Childhood Rhabdomyosarcoma | Recurrent Childhood Soft Tissue Sarcoma | Recurrent Childhood Malignant Germ Cell Tumor | Recurrent... and other conditions

United States
Exelixis

Completed

Safety Study of XL184 (Cabozantinib) in Combination With Temozolomide and Radiation Therapy in the Initial Treatment of Adults With Glioblastoma

Glioblastoma | Gliosarcoma | Giant Cell Glioblastoma

United States
National Cancer Institute (NCI)

Completed

Vorinostat and Temozolomide in Treating Young Patients With Relapsed or Refractory Primary Brain Tumors or Spinal Cord Tumors

Recurrent Childhood Medulloblastoma | Recurrent Childhood Ependymoma | Childhood Atypical Teratoid/Rhabdoid Tumor | Extra-adrenal Paraganglioma | Childhood Choroid Plexus Tumor | Childhood Craniopharyngioma | Childhood Ependymoblastoma | Childhood Grade I Meningioma | Childhood Grade II Meningioma | Childhood... and other conditions

United States, Canada

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