Search clinical trials for: Thiazide diuretics

Total 1896 results

University of California, San Francisco
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Tufts... and other collaborators

Completed

The Effect of SLC19A3 Inhibition on the Pharmacokinetics of Thiamine

Vitamin B1 Deficiency | Thiamine Deficiency

United States
University of Alberta

Recruiting

18F-DOPA II - PET Imaging Optimization

Parkinson Disease | Brain Tumor | Neuroendocrine Tumors | Lewy Body Disease | Neuroblastoma | Congenital Hyperinsulinism

Canada
University of California, San Diego

Completed

Treatment of OSA Associated Hypertension With Nebivolol or Hydrochlorothiazide (nebhctz)

Hypertension
Roxane Laboratories

Completed

Bioequivalency Study of Losartan Potassium/Hydrochlorothiazide 100 mg /25 mg Tablet Under Fed Conditions

Hypertension

United States
Novartis

Completed

Aliskiren HCTZ Compared to Amlodipine in Patients With Stage 2 Systolic Hypertension and Diabetes Mellitus (ASTRIDE)

Hypertension | Diabetes Mellitus

United States
Sir Mortimer B. Davis - Jewish General Hospital
Merck Frosst Canada Ltd.

Terminated

Losartan Versus Hydrochlorothiazide in Reversing Remodeling of Small Arteries in Pre-Hypertensive Pre-Diabetic Subjects

Pre-diabetes | Pre-hypertension

Canada
Boehringer Ingelheim

Completed

Safety Evaluation of Telmisartan Plus Hydrochlorothiazide in Patients With Mild-to-Moderate Hypertension

Hypertension
Boehringer Ingelheim

Completed

Telmisartan Compared to Losartan + Hydrochlorothiazide in Patients With Mild-to-moderate Essential Hypertension

Hypertension
Kurume University

Completed

Morning Hypertension and Preminent Therapy Study

Hypertension

Japan
Takeda

Completed

Efficacy and Safety of Azilsartan Medoxomil Co-Administered With Chlorthalidone in Participants With Essential Hypertension

Hypertension

United States
AstraZeneca

Completed

Antihypertensive Efficacy and Safety of Candesartan/HCT 32/25 mg in Comparison With Individual Components and Placebo

Hypertension

Russian Federation, Latvia, Romania, Slovakia, Belgium, Malta
Ranbaxy Laboratories Limited

Completed

Bioequivalence Study of Benazepril HCl / Hydrochlorothiazide 20 mg/ 25 mg Tablets Under Fasting Conditions

Healthy

United States
Ranbaxy Laboratories Limited

Completed

Bioequivalence Study of Benazepril HCl / Hydrochlorothiazide 20 mg/ 25 mg Tablets Under Fed Conditions

Healthy

United States
Henry Ford Health System

Withdrawn

Acamprosate and Methazolamide for Essential Tremor

Essential Tremor

United States
University of Texas Southwestern Medical Center
Novartis Pharmaceuticals

Withdrawn

Regression of Fatty Heart by Valsartan Therapy

Metabolic Syndrome | Lipotoxicity

United States
Torrent Pharmaceuticals Limited

Completed

Bioequivalence Study of Losartan Potassium and Hydrochlorothiazide (100 mg / 25 mg Tablet) [Test Formulation, Torrent Pharmaceuticals Ltd., India] Versus Hyzaar® (100 mg / 25 mg Tablet) [Reference Formulation, Merck & Co., Inc., USA] in Healthy Human Volunteers Under Fasting Conditions.

Healthy
Niguarda Hospital
Associazione Nazionale Medici Cardiologi Ospedalieri

Terminated

REWORD-HF REverse WOrsening Renal Function in Decompensated Heart Failure (REWORD-HF)

Acute Decompensated Heart Failure

Italy
Göteborg University

Completed

A Short Term Open, Randomized Cross-over Trial Exploring the Effect of Carbonic Anhydrase Inhibition by Acetazolamide on Sleep Apnea Associated Hypertension and Vascular Dysfunction

Hypertension | Obstructive Sleep Apnea | Blood Pressure | Sleep-Disordered Breathing

Sweden
Boehringer Ingelheim

Completed

Influence of Food on the Bioavailability of Two Doses of Telmisartan/HCTZ Fixed-dose Combination in Japanese Healthy Male Volunteers

Healthy
Boehringer Ingelheim

Completed

A Randomised, Parallel-group, Double-blind, Double-dummy Study to Compare the Effects of Lacidipine Versus Bendrofluazide on Markers of Platelet Activation and Haemorheological Factors in Hypertensive Patients

Hypertension
Bayer

Completed

Xirtam H Combination In the Treatment of Hypertension Evaluation Study. (XCITE)

Hypertension

India
University of Florida

Completed

Uric Acid and Hypertension in African Americans

Heart Diseases | Cardiovascular Diseases | Hypertension

United States
GlaxoSmithKline

Completed

A Study To Compare Effects Of GSK189075 In Combination With Either Furosemide Or Hydrochlorothiazide

Diabetes Mellitus, Type 2 | Type 2 Diabetes Mellitus

United States
Radboud University Medical Center

Completed

Nijmegen Antihypertensive Management Improvement Study (NAMIS)

Primary Hypertension

Netherlands
Takeda

Completed

Efficacy and Safety of Azilsartan Medoxomil Combined With Chlorthalidone in Participants With Moderate to Severe Hypertension

Hypertension

United States, Chile, Russian Federation, Mexico, Peru
Teva Pharmaceuticals USA

Completed

Losartan Potassium/Hydrochlorothiazide 100/25 mg Tablets in Healthy Subjects Under Non-Fasting Conditions

Healthy

United States
Larissa University Hospital

Unknown

Dopamine in Acute Decompensated Heart Failure (DAD-HF) Trial (DAD-HF)

Acute Heart Failure

Greece
Brigham and Women's Hospital

Unknown

The Effect of Providing Free Samples of Generic Cardiovascular Medications to Physicians (SAMPLES)

Hypertension | Hyperlipidemia

United States
Daiichi Sankyo, Inc.

Completed

An Examination of the Safety and Blood Pressure Lowering Effect of Increasing Doses of Benicar® and Benicar® HCT in Patients With Hypertension

Hypertension

United States
Beijing Tiantan Hospital

Recruiting

Stent Implantation Versus Medical Therapy for Idiopathic IntracraniaL Hypertension (SIMPLE)

Venous Sinus Stenosis | Idiopathic Intracranial Hypotension

China
University of Calgary

Recruiting

Hydroxychloroquine and Indapamide in SPMS

Multiple Sclerosis, Secondary Progressive

Canada
Organon and Co

Completed

A 52 Week Study to Evaluate the Effects of Losartan With or Without HCTZ on Plasma Glucose, Metabolic Parameters, Blood Pressure in Hypertensive Patients With Metabolic Syndrome (0954A-331)

Hypertension | Metabolic Disorder
Northwestern University
National Heart, Lung, and Blood Institute (NHLBI); American Society for Transplantation

Withdrawn

Mechanism of Hypertension Treatments in Liver Transplant Recipients (BLOCK LTR-HTN)

High Blood Pressure | Liver Transplant | Renal Function Abnormal

United States
Organon and Co

Completed

Evaluation of the Antihypertensive Effect of Hyzaar(R) and Cognitive Function of Hypertensive Patients (0954A-322)

Hypertension
EMS

Withdrawn

Efficacy and Safety of Leningrado 5 Association in the Treatment of Hypertension

Arterial Hypertension
Maruho Co., Ltd.

Unknown

Topical Ionic Contra-Viral Therapy in Actinic Keratosis

Actinic Keratosis

Netherlands
Roxane Laboratories

Completed

Bioequivalency Study of Losartan Potassium/Hydrochlorothiazide 100 mg/25 mg Tablet Under Fasted Conditions

Hypertension

United States
Massachusetts General Hospital

Completed

Comparison of Temazepam and Acetazolamide to Treat Difficulty Sleeping at High Altitude

High-altitude Sleep Disturbance

Nepal
Boehringer Ingelheim

Completed

Telmisartan With or Without Hydrochlorothiazide in Patients With Mild-to-moderate Hypertension

Hypertension
Ardea Biosciences, Inc.

Completed

Metformin and Furosemide Drug-Drug Interaction Study

Healthy

United States
Merck Sharp & Dohme LLC

Completed

Antihypertensive Response to Losartan and Genetic Polymorphisms

Hypertension
Ranbaxy Laboratories Limited

Completed

Bioequivalence Study of Fosinopril Sodium / Hydrochlorothiazide 20/ 12.5 mg Tablets Under Fed Conditions

Healthy

United States
Sanofi
Bristol-Myers Squibb

Completed

AMISH : Aprovel for Management of Isolated Systolic Hypertension

Hypertension

Korea, Republic of, Mexico, Taiwan, Thailand, Philippines, Chile, China, Indonesia
James A. Tumlin, MD
Nelson Kopyt, MD

Recruiting

Safety and Efficacy of Two Year of RAAS Alone or in Combination With Spironolactone Therapy (MRA-ACE)

Renal Insufficiency, Chronic | Diabetic Nephropathy Type 2

United States
RenJi Hospital
Ruijin Hospital

Completed

Risk Stratification of Heart Failure in Cardiomyopathies. (EARLY-MYO-HF)

Cardiomyopathy With Unknown Etiology

China
Baylor Research Institute
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Impact of Medical and Surgical Therapy on Functional Mitral Regurgitation

Heart Diseases | Cardiovascular Diseases | Coronary Disease

United States
China National Center for Cardiovascular Diseases
Peking University First Hospital; Beijing Children's Hospital

Recruiting

Study of Drug Therapy for Pediatric Heart Failure

Heart Failure Congenital

China
China National Center for Cardiovascular Diseases
Shanghai Children's Medical Center; Chinese Academy of Medical Sciences, Fuwai... and other collaborators

Recruiting

Study of Innovative Drug Strategies in Improving Left Ventricular Function After Mitral Repair

Congenital Mitral Insufficiency

China
China National Center for Cardiovascular Diseases
Shanghai Children's Medical Center; Chinese Academy of Medical Sciences, Fuwai... and other collaborators

Recruiting

Study of Innovative Drug Treatment Therapy for Pediatric Mitral Regurgitation

Congenital Mitral Insufficiency

China
Postgraduate Institute of Medical Education and...

Completed

Role of Midodrine and Tolvaptan in Patients With Cirrhosis With Refractory or Recurrent Ascites

Cirrhosis | Refractory/Recurrent Ascites

India

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