Search clinical trials for: Thiotepa--escalated dose

Total 6458 results

Innovent Biologics (Suzhou) Co. Ltd.

Completed

Single Dose Tolerability and Pharmacokinetics of IBI112 in Healthy Subjects

Healthy Subjects

China
University of Florida
Live Like Bella Pediatric Cancer Research

Completed

Conditioning Regimen for Allogeneic Hematopoietic Stem-Cell Transplantation

Common Variable Immunodeficiency | Severe Combined Immunodeficiency | Sickle Cell Disease | Hurler Syndrome | Chronic Granulomatous Disease | Thalassemia | Wiskott-Aldrich Syndrome | Adrenoleukodystrophy | X-linked Lymphoproliferative Disease | Diamond Blackfan Anemia | Bone Marrow Failure Syndrome | Hemophagocytic... and other conditions

United States
Tata Medical Center

Completed

Dose Escalation Versus Standard in Laryngopharyngeal Cancers (INTELHOPE)

Malignant Neoplasm of Oropharynx Stage III | Malignant Neoplasm of Larynx Stage III | Malignant Neoplasm of Hypopharynx Stage III | Malignant Neoplasm of Oropharynx Stage IVa | Malignant Neoplasm of Oropharynx Stage IVb | Malignant Neoplasm of Larynx Stage IV | Malignant Neoplasm of Hypopharynx... and other conditions

India
Royal Marsden NHS Foundation Trust

Completed

A Phase I/II Study of the Use of Intensity Modulated Radiotherapy (IMRT) in Cancer of the Thyroid, Larynx and Hypopharynx

Locally Advanced Larynx, Hypopharyngeal Squamous Cell Cancers | Locally Advanced Thyroid Cancers

United Kingdom
University Health Network, Toronto

Completed

Intensity Modulated Radiation Therapy (IMRT) Pelvic Nodes Prostate

Adenocarcinoma of the Prostate

Canada
Cairo University

Unknown

A Study Comparing Hypofractionated Dose Escalated VMAT to Conventional CCRT in Locally Advanced Head and Neck Cancer

Locally Advanced Head and Neck Cancer
National University Hospital, Singapore
Tan Tock Seng Hospital

Unknown

Hypofractionated Intensity Modulated Chemoradiotherapy to Treat Locally Advanced Non-Small Cell Lung Cancer

Stage III Non-Small Cell Lung Cancer

Singapore
Technische Universität Dresden

Not yet recruiting

Individualized Radiation Dose Prescription in HNSCC Based on F-MISO-PET Hypoxia-Imaging (INDIRA-MISO)

Head and Neck Squamous Cell Carcinoma

Germany
University of Alabama at Birmingham

Active, not recruiting

A Dose Escalation Trial of Five Fraction Stereotactic Radiation Therapy for Brain Metastases (RAD1705)

Brain Metastases

United States
Peter MacCallum Cancer Centre, Australia

Completed

High Intensity Functional Image Guided Vmat Lung Evasion (HI-FIVE)

Non Small Cell Lung Cancer Stage III

Australia
Allegheny Singer Research Institute (also known...

Recruiting

EXErcise Regimen Designed to Improve Functional Mobility, Body Composition, and Strength After Treatment for Cancer (EXERT-C)

Cancer

United States
The Netherlands Cancer Institute

Completed

Adaptive Dose-Escalated Multi-modality Image-guided RadiothErapy (ADMIRE)

Head and Neck Cancer

Netherlands
Micropharma Limited

Completed

Effect of L. Reuteri NCIMB 30242 on Plasma Bile Acid Profile

Hypercholesterolemia
Olfred Hansen
Odense University Hospital; Aarhus University Hospital; Rigshospitalet, Denmark; Herlev Hospital and other collaborators

Recruiting

Novel Approach to Radiotherapy in Locally Advanced Lung Cancer Concomitant Navelbine®

NSCLC

Denmark
AHS Cancer Control Alberta

Recruiting

Dose-escalated Adaptive Radiotherapy of Thoracic Disease for Small Cell Lung Cancer (DARTS)

Small Cell Lung Cancer

Canada
Cancer Trials Ireland

Active, not recruiting

Spine SABR - Dose-escalated Stereotactic Ablative Body Radiotherapy (SABR) for Solid Tumour Spine Metastases (Spine-SABR)

Solid Tumor Spine Metastases

Ireland
Scorpion Therapeutics, Inc.

Recruiting

First-In-Human Study of STX-721 in Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer Harboring EGFR Exon 20 Insertion Mutations

Non-Small Cell Lung Cancer | NSCLC | EGFR/HER2 Exon 20 Insertion Mutation

United States, Taiwan
Ass. Prof. Jan Nyman

Terminated

Phase II Randomized Study on Locally Advanced NSCLC Escalated Dose on Individual Basis Treatment With Radiochemotherapy (PLANET)

Non Small Cell Lung Cancer | Locally Advanced Disease

Sweden
University of Aarhus
Danish Cancer Society

Recruiting

Escalated Dose Proton Therapy Within the Multimodality Treatment of Glioblastoma Patients

Glioblastoma

Denmark
Accelerated Community Oncology Research Network
Bayer

Terminated

Randomized Study of Sorafenib Dose Escalation in Patients With Previously Untreated Metastatic Renal Cell Carcinoma

Renal Cell Carcinoma

United States
The Netherlands Cancer Institute

Recruiting

A Pilot Study of Dose dE-eScalaTion IN prostATe radIOtherapy usiNg the MRL (DESTINATION)

Prostate Cancer

Netherlands
Taiho Pharmaceutical Co., Ltd.

Recruiting

A Study of TAS3731 in Healthy Adults

Healthy Adult Males

Japan
Sheba Medical Center
Karyopharm Therapeutics Inc

Unknown

Selinexor Combined With Standard Chemoradiation as Neoadjuvant Treatment in Locally Advanced Rectal Cancer

Rectal Neoplasms

Israel
Oregon Health and Science University
University of Michigan; University of Texas; HealthPartners Institute; Case Western... and other collaborators

Completed

Evaluating System Change to Advance Learning and Take Evidence to Scale (ESCALATES) (ESCALATES)

Program Evaluation
Rajiv Gandhi Cancer Institute & Research Center...
Varian, a Siemens Healthineers Company

Recruiting

Dose Escalation Using Hypoxia-adjusted Radiotherapy (DE-HyART)

Head and Neck Squamous Cell Carcinoma

India
Institute of Medical Biology, Chinese Academy of...
Guangxi Center for Disease Control and Prevention

Completed

Clinic Trial to Evaluate the Safety and Immunogenicity by Different Sequential Schedules of bOPV and IPV

Poliomyelitis

China
Duke University

Recruiting

Radiotherapy Dose De-escalation in HPV-Associated Cancers of the Oropharynx

Oropharynx Cancer

United States
Jiangsu HengRui Medicine Co., Ltd.

Unknown

A Safety and Efficacy Study of SHR4640 and Febuxostat in Subjects With Hyperuricemia

Hyperuricemia
University Hospital, Bonn

Completed

Therapy Optimization Trial for the Treatment of Relapsed or Refractory Brain Tumors in Children (HIT-REZ-2005)

Ependymomas | Recurrent Brain Tumors | Supratentorial PNETs | Medulloblastomas

Germany
Galapagos NV

Completed

First-in-Human Single and Multiple Dose of GLPG2222

Healthy

Belgium
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of JNJ-42721458 in Healthy Male Participants

Healthy

Belgium
Guangzhou Henovcom Bioscience Co. Ltd.

Completed

A Study of HNC042 in Healthy Subjects to Evaluate the Safety, Tolerability, and Pharmacokinetics.

Healthy

United States
Sichuan Haisco Pharmaceutical Group Co., Ltd

Completed

Safety, Tolerability and Pharmacokinetics of FTP-198 in Healthy Australian Volunteers

Healthy

Australia
NYU Langone Health

Recruiting

Adaptive Treatment De-escalation in Favorable Risk HPV-Positive Oropharyngeal Carcinoma

HPV Positive Oropharyngeal Squamous Cell Carcinoma | Oropharyngeal Carcinoma

United States
Memorial Sloan Kettering Cancer Center
Massachusetts General Hospital; Northwestern University; University of Calgary; Schering-Ploug... and other collaborators

Completed

Intensive Chemotherapy and Autotransplantation for Patients With Newly Diagnosed Anaplastic Oligodendroglioma

CNS Cancer | CNS BRAIN

United States
Sun Yat-sen University

Recruiting

De-escalated Radiotherapy for Primary Tumor After Neoadjuvant Therapy With Toripalimab Plus Chemotherapy for Nasopharyngeal Carcinoma

Nasopharyngeal Carcinoma | IMMUNOTHERAPY | Radiotherapy; Complications

China
GEN İlaç ve Sağlık Ürünleri A.Ş.
Sulfateq B.V.

Recruiting

A First-In-Human Study of Single and Multiple Ascending Doses of Oral SUL-238 in Healthy Subjects

Healthy Subjects

Turkey
Enterprise Therapeutics Ltd

Completed

A First in Human Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Single and Multiple Ascending Doses of Inhaled ETD001 in Healthy Subjects

Cystic Fibrosis

United Kingdom
Duke University
Centers for Disease Control and Prevention

Completed

Alternate Dosing Schedules Study for HPV Vaccine (ADS) (ADS)

Cervical Cancer | Genital Warts

United States
Rutgers, The State University of New Jersey
Centers for Disease Control and Prevention

Completed

Experimentally Testing the Effectiveness of a Campus-based Bystander Intervention

Violence | Helping Behavior | Sexual Assault and Rape | Assaultive Behavior

United States
The Netherlands Cancer Institute

Terminated

Intensified IAA With PBPC Support in Breast Tumors With Evidence of a HRD

Breast Cancer

Netherlands
Royal Marsden NHS Foundation Trust

Recruiting

Dose De-escalation in Prostate Radiotherapy Using the MRL (DESTINATION)

Prostate Adenocarcinoma

United Kingdom
Basilea Pharmaceutica

Completed

Safety, Pharmacokinetics, Bioavailability, Food Effect, Drug-Drug Interaction Study of APX001 Administered Orally

Fungal Infection

Netherlands
Assistance Publique - Hôpitaux de Paris
Janssen, LP

Completed

Study of Dose Escalation of Abiraterone Actetate in Prostate Cancer (OPTIMABI)

Prostate Cancer

France
Chinook Therapeutics, Inc.

Active, not recruiting

Safety and Tolerability of BION-1301 in Healthy Volunteers and Adults With IgA Nephropathy (IgAN)

IgA Nephropathy

Korea, Republic of, United States, United Kingdom
Galapagos NV

Completed

First-in-Human Single and Multiple Dose of GLPG1837

Healthy

Belgium
Chiesi Farmaceutici S.p.A.

Completed

Phase II Study to Evaluate the Cardiac Safety of 2 Doses of CHF5993 Both Combined With CHF1535 BID Versus CHF1535 BID in Patients With Moderate to Severe COPD (CARSAF)

Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)

Bulgaria, Germany, Hungary, Poland, Russian Federation, United Kingdom
Suzhou Alphamab Co., Ltd.

Recruiting

KN057 Multiple Dose Study in Moderately Severe to Severe Hemophilia

Hemophilia

China
Pluristem Ltd.

Completed

Safety and Efficacy of Allogeneic Cells for the Treatment of Intermittent Claudication(IC)

Intermittent Claudication | Peripheral Artery Disease

United States, Germany, Korea, Republic of, Israel
Holdsworth House Medical Practice
ScalaMed

Withdrawn

Patients Empowered With Digital Scripts: ScalaMed (PEDS)

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Search clinical trials for: Thiotepa--escalated dose

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