Search clinical trials for: Ticagrelor 180mg loading dose and 90mg bid maintenance dose

Total 446 results

University of Patras

Completed

Ticagrelor vs High Dose Clopidogrel in Patients With ST Elevation Myocardial Infarction Post Fibrinolysis

ST Elevation Myocardial Infarction | Fibrinolysis | P2Y12 Inhibitor

Greece
Guangdong Raynovent Biotech Co., Ltd

Completed

Study in Chinese Healthy Adults to Evaluate the Safety, Tolerability and Pharmacokinetics on ZSP0678, and the Effect of Food on ZSP0678 Pharmacokinetics

Nonalcoholic Steatohepatitis

China
Galapagos NV

Completed

This is a Study to Evaluate the Effect of Aging of Multiple Doses of GLPG1205 in Healthy Subjects

Healthy | Elderly

Belgium
University of Patras

Completed

High (100mg) Versus Standard (60mg) Loading Dose of Prasugrel in Patients With ST-elevation Myocardial Infarction (STEMI), Undergoing Primary Percutaneous Coronary Intervention (PCI)

Platelet Reactivity

Greece
GlaxoSmithKline

Completed

A First Time in Human Study to Assess GSK2336805 in Healthy Volunteers and Single Doses in Chronically Infected Hepatitis C Patients.

Hepatitis C

United States
Yuhan Corporation

Completed

Safety/Tolerability and Pharmacokinetics/Pharmacodynamics of YH4808 After Oral Administration in Healthy Male Subjects

Healthy

Korea, Republic of
Medical University of Vienna

Unknown

High "on Treatment" Platelet Reactivity in the Intensive Care Unit

Critical Illness

Austria
Daiichi Sankyo, Inc.
Eli Lilly and Company

Completed

Pharmacodynamic Evaluation of Switching From Ticagrelor to Prasugrel in Subjects With Stable Coronary Artery Disease (SWAP-2)

Coronary Artery Disease

United Kingdom, United States
Dong-A ST Co., Ltd.

Completed

Study to Evaluate the Efficacy and Safety of Intra-articular DA-5202 in Patients With Osteoarthritis of the Knee

Osteoarthritis, Knee

Korea, Republic of
Novartis Pharmaceuticals

Completed

Effect of AQW051 on Cognitive Function in Patients With Chronic Stable Schizophrenia

Schizophrenia Disorders

United States
Taiho Pharmaceutical Co., Ltd.

Completed

A Study of TAS-303 in Female Patients With Stress Urinary Incontinence

Stress Urinary Incontinence

Japan
Shire

Terminated

SPD489 Low Dose and High Dose Ranges When Added to Stable Doses of Antipsychotic Medications in Clinically Stable Adults With Negative Symptoms of Schizophrenia

Schizophrenia

United States
AstraZeneca

Completed

Brilinta Taiwan Post Approval Safety Study

Non ST-elevation Myocardial Infarction

Taiwan
Icahn School of Medicine at Mount Sinai
AstraZeneca

Completed

Reversing Ticagrelor's Effects With Fresh Platelets

Coronary Artery Disease

United States
USDA, Western Human Nutrition Research Center
Sonomaceuticals LLC

Completed

Metabolic Response to Chardonnay Grape Marc Powder

Obesity | Dyslipidemia

United States
LG Chem

Completed

An Ascending Dose, Single/Multiple Dosing, Food Effect Clinical Trial to Evaluate Pharmacokinetics, Safety and Tolerability in Healthy Subjects After Oral Administration of Gemigliptin (Phase I)

Type 2 Diabetes Mellitus

China
Haisco Pharmaceutical Group Co., Ltd.

Unknown

To Evaluate the Efficacy and Safety of HSK16149 Capsule in Chinese Patients With Diabetic Peripheral Neuropathic Pain

Diabetic Peripheral Neuropathic Pain

China
Daping Hospital and the Research Institute of Surgery...
AstraZeneca

Unknown

Effect of Rosuvastatin Therapy on HDL2 Level

Coronary Heart Disease | Hyperlipemia

China
Chong Kun Dang Pharmaceutical

Completed

CKD-355 Drug-drug Interaction Study (CKD-355 DDI P1)

Central Nervous System Diseases

Korea, Republic of
Medicines for Malaria Venture
Cross Research S.A.

Completed

Safety Tolerability & Pharmacokinetics of Co-administered Single Doses of OZ439 & Piperaquine to Healthy Subjects

Healthy

Switzerland
Biocad

Completed

Study of the Pharmacodynamics, Pharmacokinetics, Safety, and Immunogenicity of Single Escalating Doses of BCD-180 in Healthy Volunteers

Healthy

Russian Federation
University of Florida

Completed

Pharmacodynamic Evaluation of Switching From Prasugrel to Ticagrelor (SWAP3)

Coronary Artery Disease | Acute Coronary Syndrome

United States
McMaster University

Completed

Reinitiation of Anticoagulation After Temporary Withdrawal of Vitamin K Antagonist (DOSIDO)

Atrial Fibrillation | Surgery | Venous Thromboembolism | Heart Valve Disease

Canada
Arog Pharmaceuticals, Inc.

Completed

Study of Crenolanib for the Treatment of Patients With Advanced GIST With the D842-related Mutations and Deletions in the PDGFRA Gene

D842-related Mutant GIST

United States
Assiut University

Unknown

Early Versus Late Loading of Ticagrelol in Patients With STEMI

Myocardial Infarction
Shengjing Hospital
Jiangsu HengRui Medicine Co., Ltd.

Active, not recruiting

Breast Cancer Study of Stereotactic Body Radiation Therapy (SBRT) Combined Neoadjuvant Treatment

Breast Cancer

China
AstraZeneca

Completed

A Pharmacokinetic (PK) and Pharmacodynamic (PD) Dose-ranging Phase II Study of Ticagrelor in Paediatric Patients With Sickle Cell Disease (HESTIA 1)

Investigation of Platelet Aggregation in Paediatric Patients With Sickle Cell Disease

United States, Canada, United Kingdom, South Africa, Lebanon, Kenya
National Institute of Allergy and Infectious Diseases...
ViiV Healthcare

Recruiting

The LATITUDE Study: Long-Acting Therapy to Improve Treatment SUccess in Daily LifE

HIV Infections

United States, Puerto Rico
University of Oxford

Completed

Research Study to Assess New Chikungunya and Zika Vaccines in Healthy Adults in Mexico.

Chikungunya | Zika

Mexico
Boehringer Ingelheim

Completed

26-week Open Study of telmisartan40mg+amlodipine10mg or telmisartan80mg+amlodipine10 mg in Hypertension

Hypertension

Australia, Austria, Bulgaria, Czech Republic, Ireland, Italy, New Zealand, Russian Federation, Slovakia, Spain, Ukraine, United Kingdom
Biocad

Terminated

Clinical Study of the Safety and Immunogenicity of a Recombinant Viral Vector AAV5 (Adeno-Associated Virus Type 5 )-RBD (Receptor Binding Domain)-S Vaccine for the Prevention of Coronavirus Infection (COVID-19) (COVER)

COVID-19 | Coronavirus Infection

Russian Federation
Medical University of Vienna

Completed

The Role of the P2Y12 Receptor in Tissue Factor Induced Coagulation

Sepsis | Healthy Volunteers

Austria
The Christie NHS Foundation Trust

Terminated

Effect of Pegvisomant on GH/IGF-I Relationship in GHD

Severe Adult Growth Hormone Deficiency

United Kingdom
Haisco Pharmaceutical Group Co., Ltd.

Completed

Study of HSK31679 in Subjects With Hypercholesterolemia With Nonalcoholic Fatty Liver Disease（NAFLD）

Hypercholesterolemia

China
Grace Lim, MD, MS
National Institute of Mental Health (NIMH)

Recruiting

Ketamine Tolerated Dose for Postpartum Depression and Pain After Cesarean Delivery

Pain, Postoperative | Depression, Postpartum

United States
Boehringer Ingelheim
Eli Lilly and Company

Completed

Safety and Efficacy Study of Empagliflozin and Metformin for 24 Weeks in Treatment Naive Patients With Type 2 Diabetes

Hyperglycemia | Diabetes Mellitus, Type 2

United States, Brazil, Canada, Czech Republic, Egypt, France, Germany, Guatemala, Korea, Republic of, Lebanon, Malaysia, Mexico, Peru, Philippines, Russian Federation, Serbia, Spain, Taiwan, Thailand, Turkey, United Kingdom
Peking University Third Hospital

Active, not recruiting

Evaluation of the Effect of Triamcinolone at Different Doses on LIA During TKA (LIA;TKA)

Osteoarthritis, Knee

China
Laboratorios Silanes S.A. de C.V.

Completed

Study of no Pharmacokinetic Interaction Between Rosuvastatin 20mg and Ezetimibe10mg, Fixed Dose vs Individual Components

Healthy

Mexico
Boehringer Ingelheim
Eli Lilly and Company

Completed

A 16 Weeks Study on Efficacy and Safety of Two Doses of Empagliflozin (BI 10773) (Once Daily Versus Twice Daily) in Patients With Type 2 Diabetes Mellitus and Preexisting Metformin Therapy

Diabetes Mellitus, Type 2

United States, Australia, Canada, Estonia, France, Georgia, Germany, Guatemala, Italy, Latvia, Lithuania, Mexico, New Zealand, Poland, Russian Federation, South Africa, Spain, Ukraine
Genocea Biosciences, Inc.

Completed

Safety and Immunogenicity Study of Prophylactic Streptococcus Pneumoniae Vaccine

Streptococcus Pneumoniae

United States
ViiV Healthcare
GlaxoSmithKline

Completed

PENTA Fosamprenavir Study

Infection, Human Immunodeficiency Virus
Massachusetts General Hospital
Merck Sharp & Dohme LLC

Completed

Preemptive Treatment With Grazoprevir and Elbasvir for Donor HCV Positive to Recipient HCV Negative Kidney Transplant

Renal Failure

United States
University of Florida
The Medicines Company

Completed

In Vitro Pharmacodynamic Effects of Cangrelor in Ticagrelor Treated Patients

Coronary Artery Disease

United States
University of Florida
AstraZeneca

Completed

Impact of Ticagrelor Re-load on Pharmacodynamic Profiles

Coronary Artery Disease

United States
Brigham and Women's Hospital

Completed

Replication of the ISAR-REACT 5 Antiplatelet Trial in Healthcare Claims Data

Acute Coronary Syndrome

United States
Nitto Denko Corporation

Completed

JUNIPER: A Phase 2 Study to Evaluate the Safety, Biological Activity, and PK of ND-L02-s0201 in Subjects With IPF

Idiopathic Pulmonary Fibrosis

United States, Germany, Japan, United Kingdom
Merck Sharp & Dohme LLC

Completed

Comparative Study of Rocuronium With Vecuronium (Study 71101)(COMPLETED)

Anesthesia
Bial - Portela C S.A.

Completed

Tolerability, Safety and Pharmacokinetics of Four Single-doses of BIA 6-512 (Trans-resveratrol) and Their Effect on the Levodopa Pharmacokinetics

Parkinson Disease

Portugal
First Affiliated Hospital of Harbin Medical University

Unknown

Low-dose Ticagrelor in Chinese ACS Patients Undergoing PCI

Acute Coronary Syndrome

China
First Affiliated Hospital of Harbin Medical University

Unknown

Safety and Efficacy of Low-Dose Ticagrelor in Chinese Patients With NSTE-ACS

Non ST Segment Elevation Acute Coronary Syndrome

United States

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