Search clinical trials for: Tissue Plasminogen Activator (tPA)

Total 259 results

Yale University

Withdrawn

The Safety and Efficacy of Fibrinolysis in Patients With an Indwelling Pleural Catheter for Multi-loculated Malignant Pleural Effusion.

Pleural Effusion | Cancer, Lung
Neuroscience Trials Australia
China Medical University Hospital

Completed

EXTEND (International): Extending the Time for Thrombolysis in Emergency Neurological Deficits (International) (EXTEND)

Stroke

Taiwan
Second Affiliated Hospital, School of Medicine,...

Recruiting

EXtending the Time Window for Thrombolysis in Posterior Circulation Stroke Without Early CT Signs

Stroke, Acute Ischemic

China
Neuroscience Trials Australia
Melbourne Health; University of Melbourne; Commonwealth Scientific and Industrial... and other collaborators

Completed

Extending the Time for Thrombolysis in Emergency Neurological Deficits (EXTEND)

Stroke

Australia, Finland, New Zealand
Melbourne Health

Completed

Tenecteplase Versus Alteplase for Stroke Thrombolysis Evaluation Trial in the Ambulance (TASTEa)

Stroke, Acute, Stroke Ischemic

Australia
Thomas Jefferson University
Genentech, Inc.

Unknown

Quality of Life After Stroke Using a Telemedicine-based Stroke Network (STROKE TeleQOL)

Stroke

United States
University of Virginia
National Institute of Neurological Disorders and Stroke (NINDS)

Terminated

Study of Tenecteplase (TNK) in Acute Ischemic Stroke (TNK-S2B)

Stroke

United States
Assiut University
Aswan University Hospital

Completed

TPA in Acute Stroke With COVID Verus Non-COVID-19 Patients (rTPA)

Acute Ischemic Stroke

Egypt
Eastern Regional Medical Center

Recruiting

Combination Tissue Plasminogen Activator (Tpa) and Dornase Alfa (Dnase) Administration Through Intrapleural Catheters for the Treatment of Loculated or Non-Draining Malignant Pleural Effusions

Loculated or Non-draining Malignant Pleural Effusions

United States
Azienda U.S.L. 1 di Massa e Carrara

Withdrawn

Efficacy and Safety of Half Dose Alteplase Added to Heparine, in Patients With Moderate Pulmonary Embolism (MONALYSE)

Pulmonary Embolism
M.D. Anderson Cancer Center

Recruiting

Alteplase Through an Indwelling Pleural Catheter for the Management of Symptomatic Septated Malignant Pleural Effusion

Hematopoietic and Lymphoid Cell Neoplasm | Malignant Solid Neoplasm

United States
Sir Charles Gairdner Hospital
The University of Western Australia

Terminated

The Safety and Tolerability of Intra-abdominal t-PA and DNase on Peritonitis in Peritoneal Dialysis Patients

Peritoneal Dialysis | Peritoneal Dialysis, Continuous Ambulatory

Australia
Beijing Tsinghua Chang Gung Hospital

Completed

Thrombolysis Endovascular Treatment of Pulmonary Embolism (STEP)

Pulmonary Embolism | Acute Pulmonary Embolism

China
Beijing Tiantan Hospital

Recruiting

Intra-arterial Recombinant Human TNK Tissue-type Plasminogen Activator (rhTNK-tPA) Thrombolysis for Acute Large Vascular Occlusion After Successful Mechanical Thrombectomy Recanalization (ANGEL-TNK)

Ischemic Stroke, Acute

China
South West Sydney Local Health District

Recruiting

Viscoelastic Testing Guided Tissue Plasminogen Activator Treatment in Acute Respiratory Failure (VETtiPAT-ARF)

Acute Respiratory Failure | Hypercoagulability | Fibrinolysis Shutdown

Australia
Tulane University

Completed

Fibrinolysis Compared to Thoracoscopy for Pleural Infection

Pleural Diseases | Pleural Infection | Empyema | Parapneumonic Effusion

United States
Neuroscience Trials Australia

Terminated

Extending the Time for Thrombolysis in Emergency Neurological Deficits - Intra-Arterial (EXTEND-IA)

Ischemic Stroke

Australia, New Zealand
Cerevast Medical, Inc.

Unknown

Aureva Transcranial Ultrasound Device With tPA in Patients With Acute Ischemic Stroke (TRUST)

Acute Ischemic Stroke

United States
Xuanwu Hospital, Beijing

Recruiting

Intra-arterial Thrombolysis After Successful Thrombectomy for Acute Ischemic Stroke in the Posterior Circulation (IAT-TOP)

Acute Ischemic Stroke | Arterial Thrombosis | Posterior Circulation Brain Infarction

China
Penumbra Inc.

Completed

Assess the Penumbra System in the Treatment of Acute Stroke (THERAPY)

Ischemic Stroke

United States
Assiut University

Unknown

Regisry of the Stroke Patients in Assiut University Hospital

All Patients With Ischemic Cerebrovascular Stroke Aged ≥18 Years of Both Sex
D-Pharm Ltd.

Unknown

A Study of the Safety, Imaging and Clinical Outcomes of THR-18 in Acute Stroke Subjects Treated With tPA

Ischemic Stroke

Moldova, Republic of
Grifols Therapeutics LLC

Completed

A Study of Intra-thrombus Plasmin (Human) In Acute Peripheral Arterial Occlusion

Acute Peripheral Arterial Occlusion

United States, Peru, Belgium, Bulgaria, Czech Republic, Germany, India, Poland, Romania, Serbia, Slovakia, Spain
The Second Artillery General Hospital
Hunan Rui Kang Tong technology development co., LTD

Unknown

Mechanical Opening Device Implantation Following Intravenous r-tPA for Recanalization in Acute Ischemic Stroke

Ischemic Cerebrovascular Accident
National Institutes of Health Clinical Center (CC)

Completed

Low-Dose rtPA to Treat Blood Clots in Major Arm or Neck Veins

Thrombosis

United States
The Hospital for Sick Children
Canadian Institutes of Health Research (CIHR); Unity Health Toronto; Children... and other collaborators

Completed

Intrapleural DNase and Tissue Plasminogen Activator in Pediatric Empyema (DTPA Trial)

Pleural Empyema

Canada
Medtronic Neurovascular Clinical Affairs

Completed

Solitaire™ With the Intention For Thrombectomy as PRIMary Endovascular Treatment (SWIFT PRIME) Trial (SWIFT PRIME)

Acute Ischemic Stroke

United States
Boston Scientific Corporation
EKOS Corporation

Completed

Submassive and Massive Pulmonary Embolism Treatment With Ultrasound Accelerated Thrombolysis Therapy (SEATTLE II)

Pulmonary Embolism | Acute Pulmonary Embolism | Pulmonary Thromboembolism | Massive Pulmonary Embolism | Sub-massive Pulmonary Embolism

United States
Beijing Tiantan Hospital
Guangzhou Recomgen Biotech Co., Ltd.

Completed

Tenecteplase Reperfusion Therapy in Acute Ischemic Cerebrovascular Events-Ⅱ (TRACEⅡ)

Acute Ischemic Stroke

China
NHS Greater Glasgow and Clyde
University of Edinburgh; Oxford University Hospitals NHS Trust; University of...

Unknown

Alteplase-Tenecteplase Trial Evaluation for Stroke Thrombolysis (ATTEST2)

Ischemic Stroke

United Kingdom
The Cleveland Clinic
Health Resources and Services Administration (HRSA)

Completed

Enhancing Donated After Cardiac Death (DCD) Utilization With Thrombolytic Therapy

Liver Transplantation | Kidney Transplantation

United States
Boston Scientific Corporation
EKOS Corporation

Completed

Optimum Duration of Acoustic Pulse Thrombolysis Procedure in Acute Pulmonary Embolism (OPTALYSE PE)

Pulmonary Embolism and Thrombosis

United States, United Kingdom
Hospital Clinic of Barcelona
Fundacion Clinic per a la Recerca Biomédica; Fundació La Marató de TV3

Completed

Intraarterial Alteplase Versus Placebo After Mechanical Thrombectomy (CHOICE)

Stroke, Acute

Spain
NHS Greater Glasgow and Clyde
University of Glasgow

Completed

Alteplase-Tenecteplase Trial Evaluation for Stroke Thrombolysis- (ATTEST) (ATTEST)

Stroke

United Kingdom
University College, London

Recruiting

Nebulised Rt-PA for ARDS Due to COVID-19 (PACA)

COVID

United Kingdom
Universitaire Ziekenhuizen KU Leuven

Withdrawn

Surgical Stabilizer Assisted RVC With rtPA for CRVO

Central Retinal Vein Occlusion

Belgium
Angde Biotech Pharmaceutical Co., Ltd.

Unknown

Injection of Recombinant Human Tissue-type Plasminogen Activator Derivative for Acute Pulmonary Embolism(rPA) (rPA)

Acute Pulmonary Embolism
University of California, San Diego
National Institute of Neurological Disorders and Stroke (NINDS)

Completed

Intravenous Thrombolysis Plus Hypothermia for Acute Treatment of Ischemic Stroke

Stroke

United States
Washington University School of Medicine
Massachusetts General Hospital; National Heart, Lung, and Blood Institute (NHLBI) and other collaborators

Completed

Acute Venous Thrombosis: Thrombus Removal With Adjunctive Catheter-Directed Thrombolysis (ATTRACT)

Venous Thrombosis | Deep Vein Thrombosis | Postphlebitic Syndrome | Venous Thromboembolism | Post Thrombotic Syndrome

United States
University of North Carolina, Chapel Hill
Genentech, Inc.

Completed

IV vs. IA tPA (Activase) in Acute Ischemic Stroke With CTA Evidence of Major Vessel Occlusion

Ischemic Stroke

United States
Neuroscience Trials Australia
The Florey Institute of Neuroscience and Mental Health

Completed

Tenecteplase Versus Alteplase Before Endovascular Therapy for Ischemic Stroke (EXTEND-IA TNK)

Ischemic Stroke

Australia, New Zealand
Guangzhou Recomgen Biotech Co., Ltd.
Peking University; Chinese Academy of Medical Sciences, Fuwai Hospital

Completed

The Efficacy and Safety of rhTNK-tPA in Comparison With Alteplase(Rt-PA) as Fibrinolytic Therapy of Acute STEMI

Acute ST Elevation Myocardial Infarction

China
Population Health Research Institute
Heart and Stroke Foundation of Canada

Recruiting

Adjunctive, Low-dose tPA in Primary PCI for STEMI (STRIVE)

Myocardial Infarction | Percutaneous Coronary Intervention

Canada
University of Washington
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Myocardial Infarction Triage and Intervention Project (MITI)

Myocardial Infarction | Myocardial Ischemia | Heart Diseases | Cardiovascular Diseases | Coronary Disease
Johns Hopkins University
Genentech, Inc.

Completed

Safety of Intravenous Thrombolytics in Stroke on Awakening (SAIL-ON)

Stroke

United States
University of Rijeka

Completed

Neuroinflammatory Response in Patients With ICH and IVH Treated With rtPA

Brain Injuries | Intraventricular Hemorrhage | Hypertensive Intracerebral Hemorrhage
General Hospital of Shenyang Military Region

Completed

EXtending the tIme Window of Thrombolysis by ButyphThalide up to 6 Hours After Onset (EXIT-BT)

Stroke, Ischemic

China
Beijing Chao Yang Hospital

Completed

Low Dosage of rt-PA in the Treatment of Pulmonary Thromboembolism in China

Thromboembolism | Pulmonary Embolism

China
University of Windsor
The Kidney Foundation of Canada

Unknown

Trial to Compare 1.0 Versus 2.0 mg Alteplase (tPA) Dosing in Restoring Hemodialysis Catheter Function

Kidney Disease

Canada
Hospital de Clinicas de Porto Alegre

Withdrawn

Safety and Efficacy of the Penumbra™ System in Acute Middle Cerebral Artery (MCA) Stroke

Stroke

Brazil

Search clinical trials for: Tissue Plasminogen Activator (tPA)

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