Search clinical trials for: Tociliuzumab

Total 461 results

Hoffmann-La Roche

Completed

A Study of Tocilizumab + DMARDs in Patients With Moderate to Severe Active Rheumatoid Arthritis

Rheumatoid Arthritis

Italy
University of Athens

Unknown

Effects of Interleukin-6 Inhibition on Vascular, Endothelial and Left Ventricular Function in Rheumatoid Arthritis

Inflammation | Rheumatoid Arthritis

Greece
Assistance Publique - Hôpitaux de Paris

Unknown

Randomized Trial Comparing Efficacy of Adalimumab, Anakinra and Tocilizumab in Non-infectious Refractory Uveitis (RUBI)

Uveitis | Biotherapy

France
JW Pharmaceutical

Completed

To Evaluate 1 Year Extension Study of the Efficacy and Safety of Tocilizumab in Patients With Moderate to Severe Rheumatoid Arthritis

Rheumatoid Arthritis

Korea, Republic of
University Health Network, Toronto
Boehringer Ingelheim

Completed

A Study of Afatinib in Patients With Advanced Cancer With Changes in the HER Gene

Solid Tumors

Canada
Atsushi Kawakami
Gilead Sciences

Recruiting

Efficacy and Safety of Selective JAK 1 Inhibitor Filgotinib in Active Rheumatoid Arthritis Patients With Inadequate Response to Methotrexate (TRANSFORM)

Rheumatoid Arthritis | Biomarker | JAK Inhibitor | Musculoskeletal Ultrasound | IL-6 Inhibitor

Japan
Brian Miller

Completed

An Open-Label Trial of Tocilizumab in Schizophrenia

Schizophrenia

United States
Centre Hospitalier Universitaire Dijon

Recruiting

TocilizuMab discontinuAtion in GIant Cell Arteritis (MAGICA)

Giant Cell Arteritis

France
Hoffmann-La Roche
Gilead Sciences

Completed

A Study to Evaluate the Efficacy and Safety of Remdesivir Plus Tocilizumab Compared With Remdesivir Plus Placebo in Hospitalized Participants With Severe COVID-19 Pneumonia (REMDACTA)

COVID-19 Pneumonia

United States, Spain, Brazil, Russian Federation
NYU Langone Health

Active, not recruiting

A Phase II Study of the Interleukin-6 Receptor Inhibitor Tocilizumab in Combination With Ipilimumab and Nivolumab in Patients With Unresectable Stage III or Stage IV Melanoma

Melanoma

United States
Columbia University
Genentech, Inc.

Recruiting

Study of Rituximab or Tocilizumab for Patients With Steroid-Dependent Immune-Related Adverse Events (irAEs)

Advanced Solid Tumor | Immune-related Adverse Events

United States
M Abdur Rahim Medical College and Hospital
First affiliated Hospital Xi'an Jiaoting University

Unknown

Efficacy of Ramdicivir and Baricitinib for the Treatment of Severe COVID 19 Patients

Covid19 | Covid-19 ARDS

Bangladesh
Hoffmann-La Roche

Completed

A Study to Evaluate the Use of Glucocorticoids in Combination With Tocilizumab in Daily Clinical Practice (COGNOS)

Rheumatoid Arthritis

Belgium
University Hospital Inselspital, Berne
Roche Pharma AG; University of Bern

Completed

Tocilizumab for Patients With Giant Cell Arteritis

Giant Cell Arteritis

Switzerland
SURPRISE Study Group

Completed

Success of Tocilizumab in RA Patients With Remission Induction and Sustained Efficacy After Discontinuation (SURPRISE)

Rheumatoid Arthritis

Japan
Chugai Pharma Taiwan

Completed

Study of Tocilizumab in Combination With Methotrexate for Treatment of Moderate to Severe Rheumatoid Arthritis Patients

Rheumatoid Arthritis (RA)

Taiwan
Hoffmann-La Roche

Active, not recruiting

Trial of Mosunetuzumab (BTCT4465A) as Consolidation Therapy in Participants With Diffuse Large B-Cell Lymphoma Following First-Line Immunochemotherapy and as Monotherapy or in Combination With Polatuzumab Vedotin in Elderly/Unfit Participants With Previously Untreated Diffuse Large B-Cell Lymphoma

Diffuse Large B-cell Lymphoma

United States, Israel, Spain, Korea, Republic of, Poland, Taiwan
Hoffmann-La Roche

Completed

An Open-Label, Multicenter Study Evaluating the Safety, Efficacy, and Pharmacokinetics of Mosunetuzumab in Combination With Tiragolumab With or Without Atezolizumab in Participants With B-Cell Non-Hodgkin Lymphoma

Non-Hodgkin Lymphoma, Follicular Lymphoma

United Kingdom, Belgium, United States, Australia, Canada, Germany
Hoffmann-La Roche

Completed

A Study of RO7293583 in Participants With Unresectable Metastatic Tyrosinase Related Protein 1 (TYRP1)-Positive Melanomas

Uveal Melanoma | Cutaneous Melanoma | Mucosal Melanoma

Spain, United States, Belgium, Denmark, Canada, Australia
M Abdur Rahim Medical College and Hospital
First Affiliated Hospital Xi'an Jiaotong University; Cox's Bazar 250 Bed District... and other collaborators

Completed

Efficacy and Safety of Remdesivir and Tociluzumab for the Management of Severe COVID-19: A Randomized Controlled Trial

Covid19 | Covid-19 ARDS

Bangladesh
Hoffmann-La Roche

Recruiting

A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Mosunetuzumab or Glofitamab in Combination With CC-220 and CC-99282 in Participants With B-Cell Non-Hodgkin Lymphoma

Non-Hodgkin Lymphoma

United States, Israel, Italy, Spain, United Kingdom
Abramson Cancer Center at Penn Medicine
Genentech, Inc.

Recruiting

Tocilizumab and Atezolizumab in Adults With Locally Advanced or Metastatic Non-Small Cell Lung Cancer Refractory to 1st Line Immune Checkpoint Inhibitor-Based Therapy

Lung Cancer, Nonsmall Cell

United States
Thomas Wekerle
University Hospital Regensburg

Active, not recruiting

Cell Therapy for Immunomodulation in Kidney Transplantation

Kidney Transplantation

Austria
Hoffmann-La Roche

Recruiting

A Dose Escalation Study of Glofitamab (RO7082859) as a Single Agent and in Combination With Obinutuzumab, Administered After a Fixed, Single Pre-Treatment Dose of Obinutuzumab in Participants With Relapsed/Refractory B-Cell Non-Hodgkin's Lymphoma

Non-Hodgkin's Lymphoma

Belgium, Australia, Denmark, Spain, Taiwan, France, Italy, United States, Canada, Czechia, New Zealand, Poland, Finland
Hoffmann-La Roche

Completed

An Observational Study of RoActemra/Actemra (Tocilizumab) As Monotherapy in Rheumatoid Arthritis Patients in Routine Clinical Practice (ACT SOLO)

Rheumatoid Arthritis

France
University Hospital for Infectious Diseases, Croatia

Unknown

Serum IL-6 and Soluble IL-6 Receptor in Severe COVID-19 Pneumonia Treated With Tocilizumab (UHID-COVID19)

COVID-19 | Severe Pneumonia

Croatia
UCB Pharma

Completed

Efficacy and Safety of CDP6038 in Patients With Rheumatoid Arthritis With an Unsuccessful Response to Anti-Tumor Necrosis Factor (Anti-TNF) Therapy

Rheumatoid Arthritis

United States, Belgium, United Kingdom
Hoffmann-La Roche

Completed

A Study of Tocilizumab as Monotherapy and in Combination With Methotrexate Versus Methotrexate in Patients With Early Moderate to Severe Rheumatoid Arthritis

Rheumatoid Arthritis

United States, Brazil, United Kingdom, Canada, Argentina, Mexico, Austria, Israel, Colombia, Peru, Russian Federation, Philippines, Puerto Rico, Germany, Greece, Poland, Spain, France, Singapore, China, South Africa, Hungary, Denmark, Finlan... and more
Hoffmann-La Roche

Completed

A Phase Ib Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of Cibisatamab in Combination With Atezolizumab After Pretreatment With Obinutuzumab in Participants With Previously Treated Metastatic Colorectal Adenocarcinoma

Colorectal Cancer

United States, France, Denmark, Spain
Oslo University Hospital

Terminated

Tocilizumab (RoActemra) and Tranexamic Acid (Cyklokapron) Used as Adjuncts to Chronic Subdural Hematoma Surgery

Chronic Subdural Hematoma

Norway
University of Nebraska
Genentech, Inc.

Withdrawn

Ranibizumab for Edema of the mAcula in Diabetes: Protocol 4 With Tocilizumab: The READ-4 Study (READ-4)

Diabetic Macular Edema
Pirogov Russian National Research Medical University
City Clinical Hospital No.52 of Moscow Healthcare Department

Completed

COVID-19 Study at the Russian Clinical and Research Center of Gerontology of the Pirogov RNRMU

COVID-19 | Mild to Moderate

Russian Federation
Hoffmann-La Roche

Completed

A Study of RoActemra/Actemra and, if Initially Inadequately Responded to RoActemra/Actemra, Followed by MabThera/Rituxan in Patients With Rheumatoid Arthritis

Rheumatoid Arthritis

Germany
University Hospital, Ghent
Belgium Health Care Knowledge Centre

Completed

Treatment of COVID-19 Patients With Anti-interleukin Drugs (COV-AID)

COVID-19

Belgium
Herlev Hospital

Terminated

Ipilimumab, Nivolumab, Tocilizumab and Radiation in Pretreated Patients With Advanced Pancreatic Cancer (TRIPPLE-R)

Pancreatic Cancer

Denmark
AbbVie

Recruiting

Study of Oral Upadacitinib and Subcutaneous/Intravenous Tocilizumab to Evaluate Change in Disease Activity, Adverse Events and How Drug Moves Through the Body of Pediatric and Adolescent Participants With Active Systemic Juvenile Idiopathic Arthritis. (SELECT-sJIA)

Juvenile Idiopathic Arthritis

United States, Japan, Turkey, Australia, China, Spain, Italy, Germany, Brazil, United Kingdom
Australasian Leukaemia and Lymphoma Group

Recruiting

A Phase 2 Trial of GlOfitamab anD pIrtobrutinib in Mantle Cell Lymphoma Patients With Prior BTK Inhibitor Exposure. (GOlDiLOX)

Mantle Cell Lymphoma | Mantle Cell Lymphoma Refractory

Australia
Hoffmann-La Roche

Active, not recruiting

A Phase III Study Evaluating Glofitamab in Combination With Gemcitabine + Oxaliplatin vs Rituximab in Combination With Gemcitabine + Oxaliplatin in Participants With Relapsed/Refractory Diffuse Large B-Cell Lymphoma

Diffuse Large B-cell Lymphoma

United States, Korea, Republic of, United Kingdom, France, Poland, Australia, Belgium, China, Spain, Taiwan, Switzerland, Germany, Denmark, Puerto Rico
Xiaoming Gong

Completed

Phase II Trial of VDJ001 in Patients With Moderate-to-severe Active Rheumatoid Arthritis

Rheumatoid Arthritis

China
Medical University of Vienna

Completed

A Study to Evaluate the Efficacy of Tocilizumab as a Remission-Induction and Glucocorticoid-Sparing Regimen in Subjects With New-Onset Polymyalgia Rheumatica (PMR- SPARE)

Polymyalgia Rheumatica

Austria
Hoffmann-La Roche

Completed

A Study of Tocilizumab in Combination With DMARDs in Patients With Moderate to Severe Rheumatoid Arthritis (ROSE)

Rheumatoid Arthritis

United States, Puerto Rico
University Hospital Inselspital, Berne

Completed

Giant Cell Arteritis Treatment With Ultra-short Glucocorticoids and Tocilizumab (GUSTO)

Giant Cell Arteritis

Switzerland
Cedars-Sinai Medical Center

Completed

A Safety Study of Tocilizumab to Improve Transplant Rates in Highly Sensitized Patients Awaiting Kidney Transplantation

End Stage Renal Disease (ESRD)

United States
Shanghai Zhongshan Hospital

Recruiting

A Pilot Study in Severe Patients With Takayasu Arteritis.

Takayasu Arteritis | Treatment | Tocilizumab | Adalimumab

China
Brigham and Women's Hospital
Johns Hopkins University; National Institute on Aging (NIA); Rutgers University

Completed

Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM) - Tocilizumab vs Abatacept (DREAM)

Rheumatoid Arthritis

United States
Abderrahmane Mami Hospital
Eshmoun Clinical Research Center; Datametrix

Unknown

Assessment of Efficacy and Safety of Tocilizumab Compared to DefeROxamine, Associated With Standards Treatments in COVID-19 (+) Patients Hospitalized In Intensive Care in Tunisia (TRONCHER)

COVID19 | Intensive Care Unit

Tunisia
JW Pharmaceutical

Completed

Efficacy and Safety of Tocilizumab in Combination With DMARDs in Patients With Moderate to Severe Rheumatoid Arthritis

Rheumatoid Arthritis

Korea, Republic of
Peking Union Medical College Hospital

Recruiting

A Prospective Study of Tocilizumab in the Treatment of Idiopathic Retroperitoneal Fibrosis

Idiopathic Retroperitoneal Fibrosis

China
Fundació Institut de Recerca de l'Hospital de la...
Instituto de Salud Carlos III

Recruiting

Clinical Trial of the Use of Tocilizumab for Treatment of SARS-CoV-2 Infection (COVID-19) (TOCOVID)

COVID-19

Spain
Hoffmann-La Roche

Active, not recruiting

A Study to Evaluate the Safety and Efficacy of Mosunetuzumab (BTCT4465A) in Combination With Polatuzumab Vedotin in B-Cell Non-Hodgkin Lymphoma

B-cell Non-Hodgkin Lymphoma

United States, Canada, Belgium, Spain, United Kingdom

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