Search clinical trials for: Topoisomerase II Inhibitors

Total 66471 results

Alexion Pharmaceuticals
Achillion, a wholly owned subsidiary of Alexion

Completed

A Drug Interaction Study Between Danicopan and Midazolam, Fexofenadine, and Mycophenolate Mofetil in Healthy Participants

Healthy

New Zealand
Dubai Health Authority

Unknown

Injection of Hyaluronic Acid Versus Corticosteroid for Treatment of Trigger Finger

Trigger Finger

United Arab Emirates
Kaohsiung Medical University

Unknown

Botulinum Toxins Intralesional Injection for Scar Pain

Hypertrophic Scar | Scar Keloid

Taiwan
Chong Kun Dang Pharmaceutical

Completed

Clinical Trial to Evaluate the Efficacy and Safety of CKD-495 Tablet

Gastritis

Korea, Republic of
Masonic Cancer Center, University of Minnesota

Terminated

T-Cell Depleted Double UCB for Refractory AML

Acute Myelogenous Leukemia | Refractory Acute Myelogenous Leukemia

United States
PH Research, S.L.

Completed

Nab-paclitaxel in Combination With Gemcitabine in Fragile Patients With Advanced Pancreatic Cancer (FRAGANCE)

Advanced Pancreatic Cancer

Spain
Taipei Veterans General Hospital, Taiwan

Completed

Efficacy of Combined Ultrasound Guided Steroid Injection and Splinting in Patients With Carpal Tunnel Syndrome

Carpal Tunnel Syndrome
New Mexico Cancer Care Alliance

Completed

Use of Hydralazine and Valproic Acid in Advanced Solid Tumor Malignancies

Lung Cancer

United States
Colgate Palmolive

Completed

The Clinical Efficacy of Three Oral Hygiene Regimens Using a Manual Toothbrush, Toothpaste and a Mouthwash in Controlling Dental Plaque and Gingivitis

Gingivitis | Dental Plaque

Puerto Rico
Hoffmann-La Roche

Terminated

A Study of CellCept (Mycophenolate Mofetil) in Patients With Lupus Nephritis.

Lupus Nephritis

China
Boehringer Ingelheim

Completed

Drug-drug Interaction of Empagliflozin (BI 10773) and Microgynon

Healthy

Germany
University Hospital, Ghent

Completed

Sevoflurane-Remifentanil Interaction: Multiple Response Surfaces, Validation of Calibration Stimuli, Validation of the Intraoperative Isobole Concept and Investigating Remifentanil Induced Opioid Tolerance

Anesthesia

Belgium
Medical University of Vienna

Completed

Role of Nitric Oxide in Optic Nerve Head Blood Flow Regulation During Isometric Exercise in Healthy Humans

Healthy

Austria
Gildasio Castello de Almeida Junior
Hospital de Base

Completed

Evaluation of Tranilast to Treat Pterygium Before Excision (TPS)

Pterygium

Brazil
National Cancer Institute, Egypt

Completed

Dexmedetomidine-Propofol Versus Ketamine-Propofol for Sedation of CT Guided Bone Biopsy

Sedation

Egypt
Joseph Cravero

Completed

A Pilot Study of Dexmedetomidine-Propofol in Children Undergoing Magnetic Resonance Imaging

Epilepsy | Cerebral Palsy | Developmental Delay

United States
GCS Ramsay Santé pour l'Enseignement et la Recherche
Euraxi Pharma

Completed

Extension of Analgesia by Combined Injection of Dexamethasone and Dexmedetomidine After Arthroscopic Shoulder Surgery (INDEX)

Analgesia

France
AHEPA University Hospital
Skylitseio General Hospital

Completed

Beta Blockers Plus Intravenous Flecainide for Paroxysmal Atrial Fibrillation: a Real-world Chios Registry (BETAFLEC-CHIOS) (BETAFLEC-CHIOS)

Atrial Fibrillation | Arrhythmias, Cardiac

Greece
Norma Osama Abdalla Zayed
Abdelhamid, Bassant Mohamed, M.D.

Completed

Effect of IV Infusion of Lidocaine Compared to IV Infusion of Dexmedetomidine on Proinflammatory Cytokines

Inflammatory Response

Egypt
Beth Israel Deaconess Medical Center

Completed

Dexmedetomidine and IV Acetaminophen for the Prevention of Postoperative Delirium Following Cardiac Surgery (DEXACET)

Delirium

United States
Postgraduate Institute of Medical Education and...

Completed

Comparison of Opioid Based and Opioid Free Anaesthesia in Transsphenoidal Surgery

Opioid Free Anaesthesia

India
Xu Siqi

Completed

Effect of Lidocaine Plus Dexmedetomidine Infusion on PONV

Dexmedetomidine | Nausea and Vomiting, Postoperative | Lidocaine

China
Cairo University

Unknown

Comparison of Different Doses of Dexmedetomidine Effect in the Duration of Spinal Anesthesia

Spinal Anesthesia Duration

Egypt
National Cancer Institute (NCI)

Completed

Temsirolimus With or Without Cetuximab in Patients With Recurrent and/or Metastatic Head and Neck Cancer Who Did Not Respond to Previous Therapy (MAESTRO HN)

Recurrent Hypopharyngeal Squamous Cell Carcinoma | Recurrent Laryngeal Squamous Cell Carcinoma | Recurrent Oropharyngeal Squamous Cell Carcinoma | Salivary Gland Squamous Cell Carcinoma | Recurrent Lip and Oral Cavity Squamous Cell Carcinoma | Recurrent Nasopharyngeal Keratinizing Squamous... and other conditions

United States, China
National Cancer Institute (NCI)

Completed

Temsirolimus, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma

United States
Aga Khan University Hospital, Pakistan

Not yet recruiting

Dexamethasone or Dexmedetomidine as Adjunct in Fascia Iliaca Block During Positioning for Sub-arachnoid Block & Post-operative Analgesia After Femur Neck Fracture Surgery: A Randomized Control Trial

Post Operative Pain
National Cancer Institute, Egypt

Recruiting

Attenuation of Airway and Cardiovascular Responses to Extubation in Chronic Smokers

Hemodynamic | Airway Responses

Egypt
Zhenjiang First People's Hospital

Completed

Safety Study of Dexmedetomidine in Elderly Under General Anesthesia

Hip Fractures | Hip Disease

China
Calithera Biosciences, Inc

Completed

Study of the Glutaminase Inhibitor CB-839 in Solid Tumors

Renal Cell Carcinoma | Non Small Cell Lung Cancer | Mesothelioma | Solid Tumors | Triple-Negative Breast Cancer | Fumarate Hydratase (FH)-Deficient Tumors | Succinate Dehydrogenase (SDH)-Deficient Gastrointestinal Stromal Tumors (GIST) | Succinate Dehydrogenase (SDH)-Deficient Non-gastrointestinal... and other conditions

United States
Menoufia University

Active, not recruiting

Subtenon and Intravenous Dexmedetomidine Effect on Patients Undergoing Cataract Surgery

Acute Postoperative Pain

Egypt
Pontificia Universidad Catolica de Chile

Completed

Effect of Dexmedetomidine on Postoperative Glucose and Insulin Levels.

Insulin Resistance | Glucose Intolerance | Bariatric Surgery Candidate
Yeditepe University

Completed

Hydroxyzine Dihydrochloride Premedication is a Necessity for Strabismus Surgery

Strabismus | Reflex, Oculocardiac | Hydroxyzine | Bradycardia Sinus

Turkey
University of Athens

Unknown

Effect of Perioperative iv Dexmedetomidine vs. Lidocaine on Postoperative Pain, Analgesic Consumption and Recovery After Abdominal Gynaecological Surgery

Hysterectomy | Myomectomy

Greece
University of Alabama at Birmingham
National Center for Research Resources (NCRR)

Completed

The Effect of Sedation on Eye Movements (Eye Movement)

Saccadic Eye Movements

United States
Hospira, now a wholly owned subsidiary of Pfizer

Completed

Pharmacokinetics and Pharmacodynamics of Dexmedetomidine in Pediatrics Subjects

Intubated and Mechanically Ventilated Pediatric Subjects

United States, Guatemala
Southern California Institute for Research and...
National Institute of Mental Health (NIMH); University of California, Irvine

Unknown

Developing Anesthesia as Post Traumatic Stress Disorder (PTSD) Therapy

Healthy

United States
Maharashtra University of Health Sciences

Completed

Dexmedetomidine Verses Propofol for Paediatric MRI Brain (DPMP)

Brain Diseases

India
Nationwide Children's Hospital

Completed

Dexmedetomidine Versus Fentanyl Following Pressure Equalization Tube Placement

Chronic Otitis Media

United States
Affiliated Cancer Hospital & Institute of Guangzhou...

Recruiting

The Effects of Subanesthetic S-ketamine on Postoperative Delirium and Cognitive Function in the Elderly Undergoing Non-cardiac Thoracic Surgery (SKED)

Postoperative Delirium | Elderly Patients

China
Benha University

Not yet recruiting

Dexamethasone and Dexmedetomidine as an Adjuvant to Spinal Anesthesia for Elective Caesarean Sections

Pain, Postoperative
Ain Shams University

Completed

Dexmedetomidine Compared to Ketofol for Sedation in Paediatrics

Vital Signs

Egypt
Anqing Municipal Hospital
The First Affiliated Hospital of Anhui Medical University

Completed

Dexmedetomidine Combined With Lidocaine Infusion Affect Inflammation Cytokines

Anesthesia; Reaction

China
Duke University

Terminated

Pain, Agitation and Delirium (PAD) Protocol in the Duke CICU

Critical Illness | Deep Sedation | Ventilators, Mechanical

United States
Chuncheon Sacred Heart Hospital
Hallym University

Completed

The Effect of Dexmedetomidine for Suprascapular Nerve Block With Axillary Nerve Block

Postoperative Pain | Dexmedetomidine | Suprascapular Nerve Block | Arthroscopic Rotator Cuff Repair | Axillary Nerve Block | Pain Related Cytokine

Korea, Republic of
Suez Canal University

Unknown

Adjuvant to General Anesthesia in Patients Undergoing Major Abdominal Surgeries (Adjuvant)

Stress Related Disorder
Hospira, now a wholly owned subsidiary of Pfizer

Completed

Open-Label, Safety Study Evaluating the Use of Dexmedetomidine in Pediatric Subjects Undergoing Procedure-Type Sedation

Ultrasound | CT Scans | MRIs

United States, Puerto Rico
University Hospital Inselspital, Berne
GE Healthcare

Completed

Effects of Two Different Sedation Regimes on Auditory Evoked Potentials and Electroencephalogram (EEG)

Critical Care | Conscious Sedation | Deep Sedation

Switzerland
University of North Carolina, Chapel Hill

Recruiting

Antiseizure Medication in Seizure Networks at Early Acute Brain Injury

Stroke | Brain Ischemia | Brain Injuries, Traumatic | Heart Arrest | Intracranial Hemorrhages | Brain Hypoxia | Coma | Hypoxia-Ischemia, Brain | Persistent Vegetative State | Brain Injuries, Acute

United States
1ST Biotherapeutics, Inc.
Merck Sharp & Dohme LLC

Recruiting

A Phase I/II, Open-label Study to Investigate the Safety, Tolerability, PK, and Preliminary Efficacy of FB849

Advanced Solid Tumor

United States
Dwight Owen
National Cancer Institute (NCI)

Recruiting

PBF-1129 and Nivolumab for the Treatment of Recurrent or Metastatic Non-Small Cell Lung Cancer

Metastatic Lung Non-Small Cell Carcinoma | Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Recurrent Lung Non-Small Cell Carcinoma

United States

Search clinical trials for: Topoisomerase II Inhibitors

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