Search clinical trials for: Total Marrow Irradiation (TMI)

Total 719 results

Ottawa Hospital Research Institute

Recruiting

Total Marrow Irradiation & Autologous Stem Cell Transplantation for Relapsed or Refractory Myeloma (TMI-ASCT)

Multiple Myeloma

Canada
Naoyuki G. Saito, M.D., Ph.D.
Indiana University

Terminated

IMRT-TMI With Fludarabine as Myeloablative Conditioning for Allogeneic HSCT

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Chronic Myeloid Leukemia | Acute Lymphocytic Leukemia

United States
Affiliated Hospital to Academy of Military Medical...

Unknown

Total Marrow and Lymphoid Irradiation and Chemotherapy for High-Risk Acute Leukemia

Acute Leukemia

China
Affiliated Hospital to Academy of Military Medical...

Unknown

Total Marrow and Lymphoid Irradiation and Chemotherapy for Myelodysplastic Syndrome or Acute Leukemia

Myelodysplastic Syndromes | Acute Leukemia

China
Fuling Zhou

Recruiting

Helical Tomotherapy in Multiple Myeloma

Multiple Myeloma

China
Hospital Universitario Dr. Jose E. Gonzalez

Recruiting

Safety and Feasibility of TMLI as Conditioning Regimen in Allogeneic Hematopoietic Stem-cell Transplantation

Acute Lymphoblastic Leukemia

Mexico
Istituto Clinico Humanitas

Recruiting

AI Algorithms to Automate the TMI by VMAT Optimization Using WB-CT/MRI and Synthetic WB-CT - The AuToMI Project (AuToMI)

Hematological Disease

Italy
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Terminated

Low-Dose Total Lymphoid Irradiation in Treating Patients With Refractory Chronic Graft-versus-Host Disease After Donor Stem Cell Transplant

Graft Versus Host Disease

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

No longer available

Emergency Use of Adoptive Immunotherapy With CMV-Specific T Cells After Donor Bone Marrow Transplant of an Infant With Immunodeficiency Syndrome and CMV Infection

Infection | Precancerous/Nonmalignant Condition

United States
Naoyuki G. Saito, M.D., Ph.D.

Withdrawn

A Dose Escalation Study of Intensity Modulated Total Marrow Irradiation (IMRT-TMI) Followed by Fludarabine as a Myeloablative Conditioning Regimen for Allogeneic Hematopoietic Stem Cell Transplantation for Patients With Relapsed and Refractory Hematologic Malignancies

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Chronic Myeloid Leukemia | Acute Lymphocytic Leukemia

United States
Maria Sklodowska-Curie Memorial Cancer Center and...

Unknown

Total Marrow Irradiation and High-dose Melphalan for Double Autologous Hematopoietic Stem Cell Transplantation in Multiple Myeloma

Multiple Myeloma

Poland
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

TBI Using IMRT (VMAT or Tomotherapy) for the Prevention of Pul Toxicities in Patients Undergoing Donor SCT

Acute Leukemia | Myelodysplastic Syndrome

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Bone Marrow Transplantation in Treating Patients With Chronic Lymphocytic Leukemia

Leukemia

United States
Weill Medical College of Cornell University
National Cancer Institute (NCI)

Recruiting

The Radiation Oncology-Biology Integration Network (ROBIN) Molecular Characterization Trial (MCT) of Standard Short Course Radiotherapy for Rectal Cancer (ROBIN)

Rectal Cancer

United States
University of Liege
KU Leuven; Maastricht University Medical Center

Completed

Allogeneic HCT With HLA-matched Donors : a Phase II Randomized Study Comparing 2 Nonmyeloablative Conditionings

Hematological Malignancies

Belgium, Netherlands
Masonic Cancer Center, University of Minnesota

Terminated

Stem Cell Transplantation for Fanconi Anemia

Fanconi Anemia

United States
Mayo Clinic
National Cancer Institute (NCI)

Completed

Bortezomib, Melphalan, and Total-Body Irradiation Before Stem Cell Transplant in Treating Patients With Multiple Myeloma

Refractory Plasma Cell Myeloma | DS Stage I Plasma Cell Myeloma | DS Stage II Plasma Cell Myeloma | DS Stage III Plasma Cell Myeloma

United States
Hong Kong Children's Hospital
The University of Hong Kong; Hong Kong Sanatorium & Hospital

Recruiting

Total Lymphoid Irradiation as Conditioning for Pediatric Haploidentical Hematopoietic Stem Cell Transplantation

Hematopoietic Organs; Disorder

Hong Kong
University of Sao Paulo

Completed

Total Lymphoid Irradiation (TLI) to Prevent Focal Segmental Glomerulosclerosis (FSGS)Recurrence in the Renal Graft

Glomerulosclerosis, Focal

Brazil
City of Hope Medical Center
National Cancer Institute (NCI)

Terminated

Total Marrow and Total Lymph Node Irradiation, Fludarabine, and Melphalan Followed By Donor Stem Cell Transplant in Treating Patients With Advanced Hematological Cancer That Has Not Responded to Treatment

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Multiple Myeloma and Plasma Cell Neoplasm | Myelodysplastic/Myeloproliferative Neoplasms

United States
Case Comprehensive Cancer Center

Recruiting

Transanal Total Mesorectal Excision for Rectal Cancer on Anal Physiology + Fecal Incontinence

Rectal Cancer

United States
Baylor College of Medicine
The Methodist Hospital Research Institute; Center for Cell and Gene Therapy...

Terminated

Total-Body Irradiation, Fludarabine, and Alemtuzumab Followed By Stem Cell Transplant in Treating Patients With Myeloproliferative Disorder, MS, AML, or CML (MPDMDSBMT)

Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders

United States
Massachusetts General Hospital

Terminated

Intentional Rejection of the Donor Graft Using Recipient Leukocyte Infusion(s) Following Nonmyeloablative Allogeneic Stem Cell Transplant (RLI)

Multiple Myeloma | Hodgkin Disease | Non Hodgkin's Lymphoma

United States
Cyclerion Therapeutics

Completed

Trial of IW-1973 (A Stimulator of Soluble Guanylate Cyclase (sGC)) in Healthy Volunteers

Healthy

United States
Stanford University

Completed

Total Body Irradiation +/- Total Lymphoid Irradiation & Anti-Thymocyte Globulin in Non-myeloablative Hematopoietic Cell Transplantation

B-cell Lymphoma | Acute Myeloid Leukemia | Myelodysplastic Syndromes | Hodgkin Lymphoma | Chronic Myelomonocytic Leukemia | Chronic Lymphocytic Leukemia | Non Hodgkin Lymphoma | Myeloproliferative Disorder | T-cell Lymphoma

United States
Sun Yat-sen University

Completed

The Feasibility and Safety of No-scar Transanal Total Mesorectal Excision for Rectal Cancer

Rectal Cancer | Surgery

China
Kantonsspital Winterthur KSW

Recruiting

Long-term Cohort Study of Mesorectal Excision for Rectal Cancer (TME-KSW)

Cancer | Rectum

Switzerland
Niguarda Hospital
Mayo Clinic

Completed

Oncological Impact of Lateral Nodes in Rectal Cancer (I-ONARC)

Colorectal Adenocarcinoma
St. Anna Kinderkrebsforschung

Unknown

ALL-SCT BFM International- HSCT in Children and Adolescents With ALL (ALL-SCT-BFMi)

Lymphoblastic Leukemia, Acute, Childhood;

Israel, Austria, Czech Republic, Denmark, France, Italy, Netherlands, Poland, Slovakia, Sweden, Turkey
Istituto Scientifico Romagnolo per lo Studio e...

Completed

Phase II Study of Up-front Chemotherapy and Neo-adjuvant Short-course Radiotherapy for Resectable Rectal Carcinoma (COLORE) (COLORE)

Rectal Carcinoma

Italy
Fondazione EMN Italy Onlus

Completed

Total Lymphoid Irradiation and Anti-Thymocyte Globulin in the Allogeneic Hematopoietic Cell Transplantation (TLI)

HEMATOLOGIC MALIGNANCIES

Italy
University of Medicine and Dentistry of New Jersey
National Cancer Institute (NCI)

Terminated

Partially HLA-Matched Irradiated Allogeneic Cellular Therapy After Reduced Intensity Total Body Irradiation

Lymphoma | Myelodysplastic Syndromes | Leukemia | Multiple Myeloma and Plasma Cell Neoplasm

United States
Masonic Cancer Center, University of Minnesota
National Marrow Donor Program

Completed

Stem Cell Transplant for Hemoglobinopathy

Sickle Cell Disease | Thalassemia | Severe Congenital Neutropenia | Diamond-Blackfan Anemia | Shwachman-Diamond Syndrome

United States
National Cancer Center, Korea

Active, not recruiting

Phase II Clinical Trial for the Evaluation of the Efficacy of Transanal TME

Rectal Cancer

Korea, Republic of
Stanford University
National Institutes of Health (NIH)

Completed

TLI & ATG for Non-Myeloablative Allogeneic Transplantation for MDS and MPD

Myelodysplastic Syndromes | Myeloproliferative Disorders | Blood Cancer

United States
University of Rochester

Terminated

Total Skeletal Irradiation in Multiple Myeloma Before Second Autologous Hematopoietic Stem Cell Transplantation

Multiple Myeloma

United States
Seoul St. Mary's Hospital

Unknown

Clinical Implications of HMGB1 in Patients Treated With Chemotherapy or Hematopoietic Stem Cell Transplantation (CHIP-SCT)

Acute Graft-versus-host Disease

Korea, Republic of
West China Hospital

Recruiting

Neoadjuvant Therapy for Locally Advanced Rectal Cancer With Fruquintinib, Toripalimab and SRT

Rectal Cancer

China
Cancer Institute and Hospital, Chinese Academy...

Unknown

Real-world Treatment Patterns and Clinical Outcomes in EGFR-mutant Unresectable Locally Advanced NSCLC

Non Small Cell Lung Cancer | Stage III Non-small-cell Lung Cancer | EGFR Mutation-Related Tumors
OHSU Knight Cancer Institute
National Cancer Institute (NCI)

Terminated

Flu,Alemtuzumab,and TBI Followed By Donor Stem Cell Chronic Phase CML

Leukemia

United States
Stanford University
National Heart, Lung, and Blood Institute (NHLBI)

Active, not recruiting

Kidney and Blood Stem Cell Transplantation That Eliminates Requirement for Immunosuppressive Drugs

Immune Tolerance

United States
The Cleveland Clinic
National Cancer Institute (NCI)

Terminated

T-Cell Depletion, Donor Hematopoietic Stem Cell Transplant (HSCT), and T-Cell Infusions in Treating Patients With Hematologic Cancer or Other Diseases

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Precancerous/Nonmalignant Condition | Secondary Myelofibrosis | Multiple Myeloma and Malignant Plasma Cell Neoplasms

United States
Stephan Busque

Recruiting

Delayed Blood Stem Transplantation in HLA Matched Kidney Transplant Recipients to Eliminate Immunosuppressive Drugs.

Immune Tolerance

United States
University of Rochester

Recruiting

Umbilical Cord Blood Transplantation From Unrelated Donors

Lymphoma | Myelodysplastic Syndromes | Multiple Myeloma | Solid Tumor | Acute Leukemia | Aplastic Anemia | Chronic Leukemia | Immune Deficiency Disorder | Congenital Hematological Disorder | Metabolism Disorder

United States
University of Alabama at Birmingham

Completed

Fludarabine / Total Body Irradiation Regimen for ALLO HCT in Acute Lymphoblastic Leukemia (FluTBI)

Adult Lymphoblastic Lymphoma

United States
Loyola University

Completed

Autologous Transplant Using Dose-Escalated Total Body Irradiation & Cyclophosphamide & Palifermin for NHL

Refractory Non-Hodgkin Lymphoma | Relapsed Non Hodgkin Lymphoma

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Total Marrow and Lymphoid Irradiation and Chemotherapy Before DSCT in Treating Patients With High-Risk ALL or AML

Recurrent Adult Acute Myeloid Leukemia | Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities | Adult Acute Myeloid Leukemia With Del(5q) | Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) | Adult Acute Myeloid Leukemia With t(16;16)(p13;q22) | Adult Acute Myeloid Leukemia With t(8... and other conditions

United States
Tata Memorial Hospital

Recruiting

Local Consolidative Radiation Therapy Plus TKI Versus TKI Alone in Driver Mutated OM-NSCLC (TARGET-01)

Non-small Cell Lung Cancer | Oligometastatic Disease | Driver Mutation

India
Massachusetts General Hospital

Completed

Renal Allograft Tolerance Through Mixed Chimerism (Belatacept)

Renal Insufficiency | Kidney Failure, Chronic

United States
Northside Hospital, Inc.

Recruiting

Reduced Intensity Fludarabine and TBI Prior to Haplo-Identical Transplantation

Hematologic Malignancy

United States

Search clinical trials for: Total Marrow Irradiation (TMI)

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