Search clinical trials for: VAD

Total 1702 results

Medtronic Cardiac Rhythm and Heart Failure

Completed

A Clinical Trial to Evaluate the HeartWare™ Ventricular Assist System (ENDURANCE SUPPLEMENTAL TRIAL) (DT2)

Chronic Heart Failure

United States
Galapagos NV

Completed

A Study to Evaluate the Effects of a Single and Multiple Oral Doses of GLPG3121 in Adult, Healthy, Male Subjects

Healthy

Belgium
Dongguan HEC TaiGen Biopharmaceuticals Co., Ltd.
R&G Pharma Studies Co.,Ltd.

Completed

To Evaluate the Safety, Tolerability, and Pharmacokinetics Profile in Healthy Chinese Volunteers of TG-2349

Healthy Chinese Volunteers

China
Hoffmann-La Roche

Completed

A Single Ascending And Multiple Ascending Dose Study of RO5271983 in Healthy Volunteers

Healthy Volunteer

New Zealand
University of Michigan
Washington University School of Medicine; National Institute of Nursing Research...

Completed

Self-Management App for Patients With Left-Ventricular Assist Devices

Heart Failure

United States
Inmagene LLC

Recruiting

Study to Evaluate IMG-004 in Healthy Participants

Healthy Participants

United States
Innovent Biologics (Suzhou) Co. Ltd.

Recruiting

A Study to Investigate the Safety, Tolerability and Pharmacokinetics of IBI356 in Healthy Participants and in Atopic Dermatitis Patients

Healthy Participants | Atopic Dermatitis Patients

China
Shanghai Jiatan Pharmatech Co., Ltd

Completed

Sudapyridine (WX-081) in Healthy Volunteers

Healthy

China
EnnovaBio Australia Pharmaceuticals Pty Ltd

Not yet recruiting

A First-in-Human SAD/MAD Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of ENC1018 in Healthy Adult Subjects

Healthy
ZYUS Life Sciences Inc.
Novotech (Australia) Pty Limited; ZYUS Life Sciences Australia Pty Ltd

Completed

Trichomylin® Safety, Tolerability & Pharmacokinetics in Healthy Adults and First in Human Osteoarthritis Pain Evaluation (HOPE)

Healthy | Osteoarthritis

Australia
Theravance Biopharma

Completed

SAD and MAD Study to Evaluate Safety, Tolerability, and Pharmacokinetics (PK) of TD-1473 in Healthy Subjects

Healthy

United States
University of Salford
Northern Care Alliance NHS Foundation Trust

Completed

Assessing the Feasibility of Including Patients With Peripheral Artery Disease in to an Established Cardiac Rehabilitation Service.

Cardiovascular Diseases | Coronary Artery Disease | Peripheral Arterial Disease | Intermittent Claudication

United Kingdom
Chiesi Farmaceutici S.p.A.

Completed

A Study to Investigate Safety, Tolerability and Pharmacokinetics of Single and Repeat Doses of CHF6333 in Healthy Subjects (CHF6333 FIH)

Cystic Fibrosis | Non-Cystic Fibrosis Bronchiectasis

Belgium
Idorsia Pharmaceuticals Ltd.

Completed

A Study to Examine the Safety, Tolerability, and Pharmacokinetics of Single- and Multiple-ascending Doses of ACT-777991 in Healthy Subjects

Healthy

Netherlands
Medtronic Cardiac Rhythm and Heart Failure

Completed

Post- Approval Study on Patients Who Received a HeartWare HVAD® During IDE Trials (HW-PAS-03)

Heart Failure

United States
Cheung Chi Wai

Completed

Electronic Visual Analogue Scale in Acute Postoperative Pain

Post-operative Pain

China
Medtronic Cardiac Rhythm and Heart Failure

Completed

The HeartWare™ Ventricular Assist System as Destination Therapy of Advanced Heart Failure: the ENDURANCE Trial (ENDURANCE)

Chronic Heart Failure

United States
JMackem Co., Ltd
Seoul National University Hospital

Recruiting

A Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics After Oral Administration of AJH-2947 in Healthy Korean and/or Caucasian Adult Male Subjects

Diabetic Neuropathies | Neuropathic Pain | Post Herpetic Neuralgia

Korea, Republic of
Pharmacobio

Recruiting

A Phase I Study of DDN-A-0101 in Healthy Volunteers and Elder People

Alzheimer Disease

Korea, Republic of
Far Eastern Memorial Hospital

Completed

The Relationship of Adiponectin in Adipose Tissue, Thy-1 in Plaques, and Inflammatory Mediators With Cardiac Diseases

Heart Surgery

Taiwan
Janssen Scientific Affairs, LLC
HCA Research Institute, LLC

Recruiting

A Study to Assess the Engagement and Usefulness of Care4Today Digital Platform for Disease Management in Coronary Artery Disease (CAD) and/or Peripheral Artery Disease (PAD) Population (IPACE-CVD)

Coronary Artery Disease (CAD) | Peripheral Artery Disease (PAD)

United States
Spero Therapeutics
Simbec Research

Completed

A Study of the Safety, Tolerability, and Pharmacokinetics of SPR720 in Healthy Volunteers

Healthy Volunteers

United Kingdom
University Hospital Schleswig-Holstein

Recruiting

Evaluation of Safety and Pharmacokinetics of Oral Controlled-ileal-release Nicotinic Acid (CIR-NA) Compared to Immediate-release Nicotinic Acid and Placebo in Healthy Subjects and Subjects With Prediabetes

Safety Issues | Pharmacokinetic

Germany
Aptabio Therapeutics, Inc.

Completed

Safety, Tolerability, PK and PD of SAD or MAD of APX-115 in Healthy Male Volunteers

Healthy | Safety

France
Syneos Health
SynerK Pharmatech (Suzhou) Limited

Recruiting

Dose Escalation of SNK-396 in Participants With Elevated Low-Density Lipoprotein Cholesterol

Elevated Low-Density Lipoprotein Cholesterol

Australia
Idorsia Pharmaceuticals Ltd.

Completed

A Study to Examine the Safety, Tolerability, and Pharmacokinetics of Single- and Multiple-ascending Doses of ACT-1014-6470 in Healthy Subjects

Healthy

Netherlands
Kowa Company, Ltd.

Completed

A Study to Evaluate the Safety of K-755 in Healthy Volunteers

Healthy

Australia
Ji Xing Pharmaceuticals Australia Pty Ltd
Novotech (Australia) Pty Limited

Recruiting

JX09 SAD/MAD in Healthy Participants

Resistant Hypertension

Australia
Chiesi Farmaceutici S.p.A.

Completed

A Study to Investigate the Safety, Tolerability and Pharmacokinetics of Inhaled CHF6001 (CHF6001Ext)

Chronic Obstructive Pulmonary Disease

United Kingdom
ReliantHeart Inc.

Terminated

Clinical Trial to Evaluate the the ReliantHeart HeartAssist 5® VAD System in Patients Awaiting Heart Transplantation

Heart Failure | Congestive Heart Failure | Cardiac Failure | Heart Failure, Left-sided

United States
7 Hills Pharma, LLC
Frontage Clinical Services, Inc.

Completed

A Phase 1 SAD and MAD Study of the Safety, Tolerability and PK of 7HP349 in Normal Healthy Male Subjects

Solid Tumor

United States
University Hospital Schleswig-Holstein

Completed

Safety and Pharmacokinetics of Oral Controlled-ileocolonic-release Nicotinamide (CICR-NAM)

Safety Issues | Pharmacokinetic

Germany
Bogomolets National Medical University

Completed

Labour Pain is a Subjective Experience. The Degree of a Woman's Suffering in Childbirth Depends on Indirect Factors

Pain, Labor

Ukraine
German Heart Institute
University Medicine Greifswald; Helmholtz Zentrum München; University of Göttingen and other collaborators

Active, not recruiting

Early Versus Emergency Left Ventricular Assist Device Implantation in Patients Awaiting Cardiac Transplantation

End Stage Heart Disease

Germany
Carelon Research
National Heart, Lung, and Blood Institute (NHLBI); Jarvik Heart, Inc.

Active, not recruiting

Pumps for Kids, Infants, and Neonates (PumpKIN)

Pediatric Heart Failure

United States
Chiesi Farmaceutici S.p.A.

Terminated

A Study to Investigate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single and Repeat Doses of CHF6297 in Healthy Subjects and Patients With COPD (CHF6297 FIH)

Chronic Obstructive Pulmonary Disease

United Kingdom
University of Exeter
Royal Devon and Exeter NHS Foundation Trust

Completed

Testing of a Valsalva Assist Device (VAD) in Healthy Volunteers Performing a Valsalva Manoeuvre

SVT | Vagal Bradycardia

United Kingdom
University of Michigan
Agency for Healthcare Research and Quality (AHRQ)

Completed

Ventricular Assist Device (VAD) Infection Prevention Survey

Heart Failure | Healthcare Associated Infection | Ventricular Assist Device

United States
University of Mauritius
Acelity; Ministry of Health and Wellness, Mauritius; Higher Education Commission...

Completed

Negative Pressure Wound Therapy in Diabetic Wounds

Diabetic Foot

Mauritius
Centre Hospitalier Universitaire, Amiens

Completed

Treatment of Primary Plasma Cell Leukaemia in Subjects Under the Age of 70 (LPP)

Multiple Myeloma

France
South Western Ambulance Service NHS Foundation...
Royal Devon and Exeter NHS Foundation Trust; Academic Health Science Centres

Completed

Evaluation of the Valsalva Assist Device to Treat SVT (EVADE)

Emergencies | SVT | Vagal Bradycardia

United Kingdom
Aydin Adnan Menderes University

Completed

Menstrual Phase and Postoperative Pain

Acute Postoperative Pain | Chronic Postoperative Pain

Turkey
Peking University People's Hospital

Unknown

A Study of PAD Versus Velcade, Cyclophosphamide and Dexamethasone (VCD) Treatment in Subjects With Multiple Myeloma

Multiple Myeloma

China
Berlin Heart, Inc

Recruiting

EXCOR Active Driving System for the EXCOR Pediatric VAD IDE Study

Heart Failure | Congenital Heart Disease | Transplant; Failure, Heart

United States
Immunocore Ltd

Recruiting

Study of IMC-I109V in Non-cirrhotic HBeAg-negative Chronic HBV Infection

Hepatitis B, Chronic

Hong Kong, Korea, Republic of, Taiwan, Denmark, United States, Australia, Romania, United Kingdom, Spain
Gilead Sciences

Completed

A Study Evaluating GS-9620 in Treatment Naive Subjects With Chronic Hepatitis B

Hepatitis B | HBV

Korea, Republic of, United States, Canada, Australia, New Zealand
Arisan Therapeutics, Inc.
United States Department of Defense; Battelle Memorial Institute; The Defense...

Recruiting

A Study to Assess the Safety, Tolerability, and Pharmacokinetics of Oral ARN-75039 in Healthy Adult Subjects

Lassa Virus Infection

United States
Shineway Pharmaceutical Co.,Ltd

Active, not recruiting

The Clinical Trial of Chinese Herbal Medicine (SaiLuoTong) Capsule

Vascular Dementia

China
Aydin Adnan Menderes University

Completed

Femoral and Epidural Block After Total Knee Arthroplasty

Acute Postoperative Pain | Chronic Postoperative Pain

Turkey
The University of Texas Health Science Center at...

Recruiting

Heating Pad for in Office Cystoscopy and Urodynamic Testing

Pain | Anxiety | Distress, Emotional

United States

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