Search clinical trials for: VP-16

Total 935 results

APR Applied Pharma Research s.a.

Terminated

Study to Evaluate the Effect on Nitrogen Retention of Two Different Posology Schemes of PKU GOLIKE PLUS 3-16 and Free AAs in Patients With Phenylketonuria

Phenylketonurias

Italy
Merck Sharp & Dohme LLC

Completed

GARDASIL™ Study in Healthy Females Between 9 and 26 Years of Age in Sub-Saharan Africa (V501-046)

Papillomavirus Infections
Jonsson Comprehensive Cancer Center
Prostate Cancer Foundation

Active, not recruiting

Prospective Exploratory Study of FAPi PET/CT in Prostate Cancer With Histopathology Validation (FAPI PET Prost)

Prostate Carcinoma | Recurrent Prostate Carcinoma | Metastatic Malignant Neoplasm in the Prostate Gland

United States
NRG Oncology
National Cancer Institute (NCI)

Recruiting

Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-small Cell Lung Cancer

Stage III Lung Cancer AJCC v8 | Stage IIB Lung Cancer AJCC v8 | Locally Advanced Lung Non-Small Cell Carcinoma

United States
M.D. Anderson Cancer Center

Recruiting

Donor Stem Cell Transplant After Chemotherapy for the Treatment of Recurrent or Refractory High-Risk Solid Tumors in Pediatric and Adolescent-Young Adults

Refractory Malignant Solid Neoplasm | Recurrent Malignant Solid Neoplasm | Recurrent Neuroblastoma | Recurrent Rhabdomyosarcoma | Refractory Neuroblastoma | Refractory Rhabdomyosarcoma | Desmoplastic Small Round Cell Tumor | Recurrent Malignant Peripheral Nerve Sheath Tumor | Ewing Sarcoma/Peripheral... and other conditions

United States
Children's Oncology Group
National Cancer Institute (NCI)

Active, not recruiting

Response and Biology-Based Risk Factor-Guided Therapy in Treating Younger Patients With Non-high Risk Neuroblastoma

Neuroblastoma | Localized Resectable Neuroblastoma | Localized Unresectable Neuroblastoma | Ganglioneuroblastoma

United States, Canada, Saudi Arabia, Puerto Rico, Australia, New Zealand
Shanghai Zerun Biotechnology Co.,Ltd
Yuxi Zerun Biotechnology Co., Ltd.

Completed

Lot Consistency Clinical Trial of Bivalent HPV Vaccine in 9 to 30 Years Old Healthy Females

HPV Infection

China
Douglas Mennin
Weill Medical College of Cornell University; Kent State University

Completed

Emotion Regulation Therapy for Clinical Worry and Rumination (ERT)

Generalized Anxiety Disorder | Depression, Anxiety | Anxiety Disorders and Symptoms | Emotional Dysfunction

United States
Taipei Medical University Shuang Ho Hospital

Completed

Effect of Ureteral Stents Length and Location on Related Symptom

Lower Urinary Tract Symptoms | Overactive Bladder Syndrome

Taiwan
Rigel Pharmaceuticals

Completed

Efficacy and Safety Study of Fostamatinib Disodium Tablets to Treat T-Cell Lymphoma

T Cell Lymphoma

United States, Canada
City of Hope Medical Center
National Cancer Institute (NCI)

Withdrawn

Whole-Body Radiation Therapy, Systemic Chemotherapy, and High-Dose Chemotherapy Followed By Stem Cell Rescue in Treating Patients With Poor-Risk Ewing Sarcoma

Ewing Sarcoma of Bone | Untreated Childhood Supratentorial Primitive Neuroectodermal Tumor | Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor | Metastatic Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor | Adult Supratentorial Primitive Neuroectodermal Tumor (PNET) and other conditions

United States
AIDS Malignancy Consortium
National Cancer Institute (NCI); Memorial Sloan Kettering Cancer Center; Janssen... and other collaborators

Recruiting

A Study of Daratumumab and Dose-Adjusted EPOCH in Plasmablastic Lymphoma

Plasmablastic Lymphoma | Ann Arbor Stage I Diffuse Large B-Cell Lymphoma | Ann Arbor Stage II Diffuse Large B-Cell Lymphoma | Ann Arbor Stage III Diffuse Large B-Cell Lymphoma | Ann Arbor Stage IV Diffuse Large B-Cell Lymphoma

United States
Fred Hutchinson Cancer Center
ADC Therapeutics

Withdrawn

Loncastuximab Tesirine in Combination With Chemotherapy Prior to Stem Cell Transplant for the Treatment of Recurrent or Refractory Diffuse Large B-Cell Lymphoma

Recurrent Diffuse Large B-Cell Lymphoma | Recurrent Primary Mediastinal (Thymic) Large B-Cell Lymphoma | Refractory Diffuse Large B-Cell Lymphoma | Refractory Primary Mediastinal (Thymic) Large B-Cell Lymphoma | Recurrent Diffuse Large B-Cell Lymphoma, Not Otherwise Specified | Recurrent High... and other conditions

United States
National Cancer Institute (NCI)
NRG Oncology

Terminated

Erlotinib Hydrochloride or Crizotinib and Chemoradiation Therapy in Treating Patients With Stage III Non-small Cell Lung Cancer

Stage IIIA Non-Small Cell Lung Cancer AJCC v7 | Stage III Non-Small Cell Lung Cancer AJCC v7 | Stage IIIB Non-Small Cell Lung Cancer AJCC v7

United States
AIDS Malignancy Consortium
National Cancer Institute (NCI); Merck Sharp & Dohme LLC; University of Arkansas and other collaborators

Completed

Vaccine Therapy in Preventing Human Papillomavirus Infection in Young HIV-Positive Male Patients Who Have Sex With Males

Precancerous Condition | Anal Cancer | Penile Cancer | Nonneoplastic Condition

United States, Puerto Rico
Duke University
Pediatric Hydrocephalus Foundation; Children's Miracle Network Hospitals

Completed

Third Ventriculostomy Versus Shunt for Children With Hydrocephalus

Communicating Hydrocephalus

United States
Memorial Sloan Kettering Cancer Center

Completed

Dose Augmented Rituximab and ICE for Pts With Primary Refractory and Poor Risk Relapsed Aggressive B-Cell NHL

Lymphoma | B-cell Non-Hodgkin's Lymphoma

United States
Assistance Publique - Hôpitaux de Paris
Imagine Institute

Completed

Characterization of the Long-term Safety, Efficacy, and Pharmacodynamics Revestive® in the Management of Short Bowel Syndrome Pediatric Patients (REVE)

Short Bowel Syndrome

France
Chinese University of Hong Kong

Completed

Manuka Honey Eye Drops VS Conventional Treatment of Meibomian Gland Dysfunction Related Dry Eye Disease

Meibomian Gland Dysfunction

China
Chengdu University of Traditional Chinese Medicine
West China Hospital

Completed

Acupuncture for the Sleep Disorder of Chronic Fatigue Syndrome

Chronic Fatigue Syndrome

China
University of Pittsburgh

Completed

Effect of Glucosamine on Joint Structure and Quality of Life (JOG)

Osteoarthritis

United States
Nobelpharma

Completed

Efficacy and Safety, Long-Term Study of NPC-16 to Treat Dysmenorrhea

Dysmenorrhea
Keymed Biosciences Co.Ltd

Not yet recruiting

A Study of CM313 Injection in Subjects With Systemic Lupus Erythematosus

Systemic Lupus Erythematosus
Memorial University of Newfoundland

Completed

Vigorous Cool Room Treadmill Training

Multiple Sclerosis | Rehabilitation | Gait Disorders, Neurologic | Neuronal Plasticity

Canada
University of Arkansas
National Cancer Institute (NCI)

Completed

A Phase I Clinical Trial of an HPV Therapeutic Vaccine

Human Papillomavirus

United States
Merck Sharp & Dohme LLC

Completed

Study of an Investigational Vaccine in Pre-Adolescents and Adolescents (Gardasil)(V501-016)

Cervical Cancer | Genital Warts
Steward St. Elizabeth's Medical Center of Boston...
National Cancer Institute (NCI)

Completed

Vaccine Therapy in Treating Patients With Recurrent or Persistent Cervical Cancer

Cervical Cancer

United States
Aerovance, Inc.

Completed

A Phase 2a Study to Investigate the Effects of Repeated Administration of AeroDerm in Subjects With Atopic Eczema

Atopic Eczema

United Kingdom
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Rituximab, Combination Chemotherapy, Filgrastim (G-CSF), and Plerixafor in Treating Patients With Non-Hodgkin Lymphoma Undergoing Mobilization of Autologous Peripheral Blood Stem Cells

Non-Hodgkin Lymphoma

United States
SATO Pharmaceutical Co., Ltd.

Active, not recruiting

Safety and Tolerability Study of SKX-16 in Subjects With Moderate to Severe Distal Subungual Onychomycosis

Onychomycosis of Toenail

United States
Merck Sharp & Dohme LLC

Completed

V501 Efficacy Study in Women Aged 18 to 26 (V501-027)

HPV Infections
Jonsson Comprehensive Cancer Center

Recruiting

Prospective Exploratory Study of FAPi PET/CT With Histopathology Validation in Patients With Various Cancers (FAPI PET RDRC)

Hematopoietic and Lymphoid Cell Neoplasm | Malignant Solid Neoplasm | Hepatocellular Carcinoma | Cholangiocarcinoma | Cervical Carcinoma | Urothelial Carcinoma | Bladder Carcinoma | Thyroid Gland Carcinoma | Neuroendocrine Neoplasm | Malignant Skin Neoplasm | Malignant Brain Neoplasm | Cancer of Unknown Primary... and other conditions

United States
National Cancer Institute (NCI)

Completed

A Pilot Study for the Treatment of Patients With Metastatic and High Risk Sarcomas and Primitive Neuroectodermal Tumors

Sarcoma | Neuroepithelioma | Osteosarcoma | Neuroectodermal Tumor, Primitive | Sarcoma, Ewing's

United States
National Cancer Institute (NCI)

Completed

Vaccine Therapy in Treating HLA-A2 Positive Patients With Melanoma

Recurrent Melanoma | Stage IIIA Melanoma | Stage IIIB Melanoma | Stage IIIC Melanoma | Stage IIB Melanoma | Stage IIC Melanoma | Stage IA Melanoma | Stage IB Melanoma | Stage IIA Melanoma

United States
St. Jude Children's Research Hospital
National Cancer Institute (NCI); Genzyme, a Sanofi Company

Completed

Clofarabine Plus Cytarabine Versus Conventional Induction Therapy And A Study Of NK Cell Transplantation In Newly Diagnosed Acute Myeloid Leukemia

Acute Myeloid Leukemia

United States, Singapore
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Iodine I 131 Tositumomab, Etoposide and Cyclophosphamide Followed by Autologous Stem Cell Transplant in Treating Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma and other conditions

United States
Kenya Medical Research Institute
University of Washington

Not yet recruiting

Effectiveness and B-memory Cell Response to QHPV Vaccine 9-years Post-vaccination Among HIV-infected Boys and Girls

HPV-Related Carcinoma
Shanghai Bovax Biotechnology Co., Ltd.

Terminated

A Phase Ⅲ Study to Evaluate the Efficacy, Immunogenicity, Safety of Quadrivalent HPV Recombinant Vaccine in Chinese Healthy Females

Cervical Cancer | CIN1 | CIN2 | CIN3 | Genital Wart | AIS | Vain I | Vain III | Vin I | Vin II | Vin III | VAIN - Vaginal Intraepithelial Neoplasia 2

China
RAI Services Company

Completed

CSD190501: A Study to Determine Subject Puffing Patterns of an Electronic Nicotine Delivery System in an Ambulatory Setting

Smoking | Tobacco Use | Tobacco Smoking | Smoking Behaviors

United States
National Cancer Institute (NCI)

Completed

Comparison of Chemotherapy Regimens in Treating Children With Relapsed or Progressive Rhabdomyosarcoma

Recurrent Childhood Rhabdomyosarcoma | Previously Treated Childhood Rhabdomyosarcoma | Alveolar Childhood Rhabdomyosarcoma | Embryonal Childhood Rhabdomyosarcoma | Embryonal-botryoid Childhood Rhabdomyosarcoma

United States
National Institute of Allergy and Infectious Diseases...

Recruiting

Clinical Trial to Evaluate the Safety, Tolerability, and Immunogenicity of 16055 NFL Delta Gly4 Env Protein Trimer and Trimer 4571 Combined With 3M-052-AF + Alum Adjuvant and Ad4-Env145NFL Viral Particles as Heterologous Prime-boost Regimens in Adult Participants Without HIV.

HIV

United States
GlaxoSmithKline

Terminated

A Study to Assess the Safety and Reactogenicity of GlaxoSmithKline (GSK) Biologicals' Human Papillomavirus (HPV) Vaccine (Cervarix) in Healthy Female Filipino Subjects Vaccinated According to the Prescribing Information From the Age of 10 Years Onwards.

Human Papillomavirus Infection Leading to Cervical Cancer

Philippines
St. Jude Children's Research Hospital
Incyte Corporation; North American Consortium for Histiocytosis; Cures Within...

Recruiting

Use Of A Response-Adapted Ruxolitinib-Containing Regimen For The Treatment Of Hemophagocytic Lymphohistiocytosis

Hemophagocytic Lymphohistiocytosis

United States
University of Florida
AstraZeneca

Terminated

Viokase 16, Viokase16 Plus Nexium and Nexium Alone (AZ)

Chronic Pancreatitis

United States
Merck Sharp & Dohme LLC

Completed

Prevention of Human Papillomavirus (HPV) in 20 to 45 Year Old Chinese Women (V501-041)

HPV Infections
University of Virginia
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Treatment With Omalizumab to Improve the Asthmatic Response to Rhinovirus Experimental Infection With Rhinovirus

Asthma

United States
National Institute of Allergy and Infectious Diseases...

Completed

First-in-Human Clinical Trial of a Mosaic Quadrivalent Influenza Vaccine Compared With a Licensed Inactivated Seasonal QIV, in Healthy Adults

Influenza | Seasonal Influenza

United States
Margarida Magalhaes-Silverman
National Cancer Institute (NCI)

Completed

Autologous Stem Cell Transplant Followed By Maintenance Therapy in Treating Elderly Patients With Multiple Myeloma

Stage I Multiple Myeloma | Stage II Multiple Myeloma | Stage III Multiple Myeloma | Primary Systemic Amyloidosis | Light Chain Deposition Disease | Extramedullary Plasmacytoma | Isolated Plasmacytoma of Bone

United States
National Cancer Institute (NCI)

Active, not recruiting

Ibrutinib Before and After Stem Cell Transplant in Treating Patients With Relapsed or Refractory Diffuse Large B-cell Lymphoma

Recurrent Diffuse Large B-Cell Lymphoma Activated B-Cell Type | Refractory Diffuse Large B-Cell Lymphoma Activated B-Cell Type

United States, Saudi Arabia
Children's Oncology Group
National Cancer Institute (NCI)

Active, not recruiting

Maintenance Chemotherapy or Observation Following Induction Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Ependymoma

Ependymoma | Anaplastic Ependymoma | Clear Cell Ependymoma | Brain Ependymoma | Cellular Ependymoma | Papillary Ependymoma

United States, Canada, Australia, New Zealand

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