Search clinical trials for: VTX-2337 plus radiotherapy

Total 218 results

Celgene
Stanford University

Terminated

VTX-2337 in Combination With Radiotherapy in Patients Low-Grade B-cell Lymphomas

Low Grade B Cell Lymphoma

United States
Celgene

Completed

Safety and Pharmacologic Study of VTX-2337 in Patients With Advanced Cancer

Lymphoma | Advanced Solid Tumors

United States
University of Washington
National Cancer Institute (NCI)

Completed

TLR8 Agonist VTX-2337 and Cetuximab in Treating Patients With Locally Advanced, Recurrent, or Metastatic Squamous Cell Cancer of Head and Neck

Tongue Cancer | Recurrent Metastatic Squamous Neck Cancer With Occult Primary | Recurrent Salivary Gland Cancer | Recurrent Squamous Cell Carcinoma of the Hypopharynx | Recurrent Squamous Cell Carcinoma of the Larynx | Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity | Recurrent Squamous... and other conditions

United States
Celgene

Terminated

A Study to Evaluate Immune Biomarker Modulation in Response to VTX-2337 in Combination With an Anti- PD-1 Inhibitor in Head and Neck Cancer

Carcinoma, Squamous Cell

United States
Gynecologic Oncology Group
National Cancer Institute (NCI)

Completed

TLR8 Agonist VTX-2337 and Pegylated Liposomal Doxorubicin Hydrochloride or Paclitaxel in Treating Patients With Recurrent or Persistent Ovarian Epithelial, Fallopian Tube, or Peritoneal Cavity Cancer

Recurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma | Ovarian Clear Cell Cystadenocarcinoma | Ovarian Endometrioid Adenocarcinoma | Ovarian Serous Cystadenocarcinoma | Malignant Ovarian Mixed Epithelial Tumor | Ovarian Brenner Tumor | Ovarian Mucinous... and other conditions

United States
Celgene

Terminated

A Phase Ib Study of Neoadjuvant of Cetuximab Plus Motolimod and Cetuximab Plus Motolimod Plus Nivolumab

Squamous Cell Carcinoma of the Head and Neck

United States
University Hospital of North Norway
Stiftelsen Helse og Rehabilitering

Completed

Transcranial Direct Current Stimulation (tDCS) as Treatment Method for Pain in Fibromyalgia

Fibromyalgia

Norway
Hospital Provincial de Castellon

Completed

Surgery Plus Intraoperative Radiotherapy as Treatment for Squamous Cell Carcinoma Over Pilonidal Disease.

Surgery | Squamous Cell Carcinoma | Pilonidal; Cyst, Malignant

Spain
Mayo Clinic
National Cancer Institute (NCI)

Terminated

TLR8 Agonist VTX-2337 and Cyclophosphamide in Treating Patients With Metastatic, Persistent, Recurrent, or Progressive Solid Tumors

Recurrent Renal Cell Carcinoma | Stage IV Skin Melanoma | Recurrent Non-Small Cell Lung Carcinoma | Stage IV Non-Small Cell Lung Cancer | Metastatic Pancreatic Adenocarcinoma | Recurrent Pancreatic Carcinoma | Stage IV Breast Cancer | Recurrent Breast Carcinoma | Recurrent Colorectal Carcinoma | Colorectal... and other conditions

United States
Shanghai Proton and Heavy Ion Center

Recruiting

A Dose Escalation Study of Proton and Carbon Ion Irradiation for HER2 Positive and Triple Negative Breast Cancer

Triple Negative Breast Cancer | HER2-positive Breast Cancer

China
Shenzhen SiBiono GeneTech Co.,Ltd

Unknown

p53 Gene Therapy for Head and Neck Malignant Tumors in Advanced Stage

Neoplasms

China
Grupo Español de Tratamiento de Tumores de Cabeza...

Completed

TPF Plus Cisplatin and Radiotherapy vs TPF Plus Cetuximab and Radiotherapy to Treat Head and Neck Cancer.

Head and Neck Cancer

Spain
Tata Memorial Centre

Recruiting

Focal Radiotherapy Plus Low Dose Craniospinal Irradiation Followed by Adjuvant Chemotherapy in WNT Medulloblastoma. (FOR-WNT2)

Medulloblastoma, WNT-activated

India
Fudan University

Recruiting

mFOLFIRINOX Plus Radiotherapy to Patients With CA19-9-normal Advanced Pancreatic Cancer (PTCA199-7)

Pancreatic Adenocarcinoma

China
Sun Yat-sen University
Wuzhou Red Cross Hospital; Fifth Affiliated Hospital, Sun Yat-Sen University; Affiliated Cancer Hospital & Institute of Guangzhou Medical University and other collaborators

Recruiting

Toripalimab Plus Concurrent Chemo-radiotherapy for Unresectable Locally Recurrent Nasopharyngeal Carcinoma

Nasopharyngeal Carcinoma | Chemotherapy | Radiotherapy | PD-1 Treatment

China
Fondazione Italiana Linfomi - ETS
Roche Pharma AG

Recruiting

Comparison Between Local Radiotherapy Alone or Combined With Obinutuzumab in Early Stage Follicular Lymphoma: the GAZEBO Trial From the Fondazione Italiana Linfomi (FIL_GAZEBO)

Follicular Lymphoma

Italy
Lei Li

Recruiting

Tislelizumab and Radiotherapy for Recurrent Cervical Cancer

Recurrent Cervical Carcinoma | Radiotherapy | Immunotherapy | Survival Outcomes | Immune Checkpoint Inhibitors | Objective Response Rate | Metastatic Cervical Carcinoma | Tislelizumab | Persistent Cervical Carcinoma | Anti-programmed Cell Death Receptor 1

China
Peking Union Medical College Hospital

Not yet recruiting

The Effect of Chemoradiotherapy in Patients With Refractory Pituitary Adenomas

Pituitary Adenomas
Sun Yat-sen University
Wuzhou Red Cross Hospital; Fifth Affiliated Hospital, Sun Yat-Sen University; Affiliated Cancer Hospital & Institute of Guangzhou Medical University and other collaborators

Recruiting

Concurrent and Adjuvant PD1 Treatment Combined With Chemo-radiotherapy for High-risk Nasopharyngeal Carcinoma

Nasopharyngeal Cancer | Chemotherapy | Radiotherapy | PD-1 Therapy

China
European Institute of Oncology

Recruiting

Accelerated Modulated Fractionation (SIB-IMRT) for Head and Neck District (FAMOSO)

Carcinoma of the Head and Neck

Italy
Celgene
Gynecologic Oncology Group

Completed

VTX-2337 and Pegylated Liposomal Doxorubicin (PLD) in Patients With Recurrent or Persistent Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer

Fallopian Tube Cancer | Epithelial Ovarian Cancer | Primary Peritoneal Cancer

United States
Fondazione Policlinico Universitario Agostino Gemelli...

Recruiting

Radiochemotherapy and Interventional Radiotherapy in Vaginal Cancer (TRIDENT)

Vaginal Cancer

Italy
Celgene

Completed

Chemotherapy Plus Cetuximab in Combination With VTX-2337 in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck

Carcinoma, Squamous Cell of Head and Neck

United States
Mianyang Central Hospital

Unknown

S-1 IMRT Versus S-1 and Cisplatin Concurrent IMRT in Inoperable Esophageal Squamous Cell Carcinoma

Esophageal Squamous Cell Carcinoma

China
Emory University
Centers for Disease Control and Prevention; Sanofi Pasteur, a Sanofi Company

Completed

Yellow Fever Virus Vaccine and Immune Globulin Study

Viremia

United States
John Sapp

Recruiting

Cohort Study - SBRT for VT Radioablation

Myocardial Infarction | Ventricular Tachycardia | Heart Disease Structural Disorder

Canada
Sun Yat-sen University

Active, not recruiting

Chemotherapy Plus Subsequent Loco-regional Radiotherapy Combined With Toripalimab in the De Novo Metastatic Nasopharyngeal Carcinoma

Nasopharyngeal Carcinoma

China
Shandong Cancer Hospital and Institute
BeiGene

Active, not recruiting

A Study of Neoadjuvant Tislelizumab With SBRT in Patients With Resectable Hepatocellular Carcinoma (Notable-HCC)

Hepatocellular Carcinoma

China
Royal Marsden NHS Foundation Trust
University College, London; The Leeds Teaching Hospitals NHS Trust; Belfast Health... and other collaborators

Unknown

Targeted Radiotherapy in Androgen-suppressed Prostate Cancer Patients. (TRAP)

Prostate Cancer | Metastasis | Toxicity Due to Radiotherapy | Circulating Tumour DNA

United Kingdom
Ontario Clinical Oncology Group (OCOG)
Canadian Institutes of Health Research (CIHR)

Terminated

Advanced Lung Cancer Treatment With Metformin and Chemo-Radiotherapy (ALMERA)

Lung Cancer

Canada
Mianyang Central Hospital

Unknown

Paclitaxel or S1 Plus Cisplatin in Concurrent Chemoradiotherapy for Squamous Cell Carcinoma of Esophagus

Esophageal Squamous Cell Carcinoma
Ludwig Institute for Cancer Research
Celgene; Cancer Research Institute, New York City; MedImmune LLC

Completed

Phase 1/2 Study of Motolimod, Doxorubicin, and Durvalumab in Recurrent, Platinum-Resistant Ovarian Cancer

Ovarian Cancer

United States, Switzerland
Medtronic Bakken Research Center
Medtronic

Completed

SMS: Substrate Modification Study in Patients Getting an Implantable Cardioverter Defibrillator (ICD) (SMS)

Tachycardia, Ventricular

Germany, Denmark
Grupo Español de Tratamiento de Tumores de Cabeza...

Completed

TPF Plus Radiotherapy and Cetuximab to Avoid Total Laryngectomy in Patients With Larynx Cancer

Head and Neck Cancer

Spain
Fudan University

Terminated

Radiotherapy Alone Versus Concurrent Chemoradiation in Low Risk NK/T-cell Lymphoma

Extranodal NK/T-cell Lymphoma, Nasal Type

China
Peking Union Medical College Hospital

Not yet recruiting

Nimotuzumab Plus Tislelizumab for Recurrent and Metastatic Cervical Cancer

Cervical Cancer
Vertex Pharmaceuticals Incorporated

Completed

A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate the Efficacy and Safety of VX-661 in Combination With Ivacaftor

Cystic Fibrosis

United States, United Kingdom, Germany, Spain, Switzerland, Canada, Netherlands, Italy, Ireland, Sweden, France, Denmark
Sun Yat-sen University

Terminated

"Sandwich" Chemotherapy With Radiotherapy in Newly Diagnosed, Stage IE to IIE, ENKTL

Treatment Refusal

China
Vertex Pharmaceuticals Incorporated

Completed

A Study to Evaluate the Efficacy and Safety of VX-661 in Combination With Ivacaftor in Subjects Aged 12 Years and Older With Cystic Fibrosis, Heterozygous for the F508del-CFTR Mutation

Cystic Fibrosis

United States, Canada, France, Spain, Israel, Australia, Austria
Cancer Institute and Hospital, Chinese Academy...

Recruiting

Phase III RCT of Radiotherapy Plus Toripalimab Versus Sorafenib in Advanced Hepatocellular Carcinoma With PVTT

Advanced Hepatocellular Carcinoma | Radiotherapy | Sorafenib | Toripalimab

China
Associazione Volontari Pazienti Oncologici
Mario Negri Institute for Pharmacological Research

Completed

Treatment of Patients With Locally Advanced Squamous Cell Carcinoma of the Head and Neck (H&N07)

Head and Neck Squamous Cell Carcinoma

Italy
Alexandria University

Completed

Total Neoadjuvant Therapy Versus Standard Neoadjuvant Chemoradiation for Locally Advanced Rectal Cancer

Rectal Cancer

Egypt
Shanxi Province Cancer Hospital

Unknown

Apatinib Plus Radiotherapy for Patients With Brain Metastases From Non-small-cell Lung Cancer

Brain Metastases
Makerere University

Completed

Radiotherapy + Metronidazole vs Radiotherapy Alone In Improving Treatment Outcomes in Advanced Cervical Cancer in Uganda

Cervix Carcinoma
University of Cologne

Recruiting

Abscopal Effect of Radiotherapy and Nivolumab in Relapsed Hodgkin Lymphoma After Anti-PD1 Therapy (AERN)

Classical Hodgkin Lymphoma

Germany
RemeGen Co., Ltd.

Terminated

A Study of the Efficacy and Safety of TACI-antibody Fusion Protein Injection (RC18) in Subjects With Inadequate Response to TNF-α Antagonists Due to Treat Moderate and Severe Rheumatoid Arthritis

Moderate and Severe Rheumatoid Arthritis

China
RemeGen Co., Ltd.

Completed

A Study of the Efficacy and Safety of TACI-antibody Fusion Protein Injection (RC18) in Subjects With Inadequate Response to MTX Due to Treat Moderate and Severe Rheumatoid Arthritis.

Moderate and Severe RheumatoId Arthritis

China
The First Hospital of Jilin University

Completed

Concurrent Involved-field Radiotherapy and Intrathecal Chemotherapy for Leptomeningeal Metastases From Solid Tumors

Leptomeningeal Metastasis

China
Hospital JP Garrahan
Hospital San Juan de Dios, Santiago

Active, not recruiting

Treatment Protocol for Non-Metastatic Unilateral Retinoblastoma (RbGALOP2)

Unilateral Retinoblastoma

Argentina
National Cancer Center Hospital East
Japan Agency for Medical Research and Development; Japan Clinical Oncology...

Recruiting

Surgery Plus Chemo Versus Chemoradiotherapy Followed by Surgery Plus Chemo for Locally Recurrent Rectal Cancer (JCOG1801)

Rectal Cancer Recurrent

Japan

Search clinical trials for: VTX-2337 plus radiotherapy

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