Search clinical trials for: Vagal nerve stimulant

Total 6556 results

Jaime Moore, MD MPH
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); University... and other collaborators

Completed

Adjunct Phentermine + Topiramate After Bariatric Surgery in 12-24 Year Olds

Adolescent | Obesity, Morbid | Drug Therapy | Bariatric Surgery | Young Adult

United States
Bayer

Completed

A Manufacturing Transfer Study Comparing the Bioequivalence of a Single Oral Dose of Claritin-D 12-Hour Extended Release Tablet From 2 Different Manufactuers Under Fed Conditions in Healthy Adult Subjects

Clinical Pharmacology

United States
New York State Psychiatric Institute
National Institute on Drug Abuse (NIDA)

Completed

Modafinil for Smoked Cocaine Self-Administration

Cocaine Dependence

United States
St. Renatus, LLC
Rho, Inc.; Triligent International

Completed

Comparison of Intranasal Kovacaine Mist, Tetracaine Alone, and Placebo for Anesthetizing Maxillary Teeth in Adults

Anesthesia

United States
Enanta Pharmaceuticals, Inc

Completed

Drug-drug Interaction Study Between EDP-305, Midazolam, Caffeine and Rosuvastatin in Healthy Volunteers.

NASH

United States
Egalet Ltd

Completed

Study to Assess the PK of Ketorolac Tromethamine Intranasal and to Assess the Effects of a Oxymetazoline Hydrochloride on the PK of Ketorolac Tromethamine

Assess Pharmacokinetics of Ketorolac Tromethamine Intranasal and Assess Effects of a Oxymetazoline Hydrochloride on the PK of Ketorolac Tromethamine

United Kingdom
Medical University of Vienna

Terminated

Perioperative Fluid Management in Patients Receiving Major Abdominal Surgery - Effects of Normal Saline Versus an Acetate Buffered Balanced Infusion Solution on the Necessity of Catecholamines for Cardiocirculatory Support (KATECHOL)

Critical Illness

Austria
Tesaro, Inc.

Completed

An Open Label, Single Dose, Three Part Study to Assess the Effects of Rolapitant (2 mg/mL IV Solution) on the Pharmacokinetics of Digoxin; Sulfasalazine; and the Cooperstown Cocktail (Midazolam, Omeprazole, Warfarin, Caffeine, and Dextromethorphan in Healthy Subjects

Chemotherapy-induced Nausea and Vomiting

United States
Medical University of Vienna

Terminated

Role of Nitric Oxide in Optic Nerve Head Blood Flow Regulation During Experimental Increase of Intraocular Pressure in Healthy Humans

Healthy

Austria
Maastricht University Medical Center

Completed

Dopaminergic Modulation of Cognition and Psychomotor Function

Dopamine Activity | Episodic Memory Consolidation | Response Preparation

Netherlands
Cardresearch

Recruiting

A Multicenter, Adaptive, Randomized, doublE-blinded, Placebo-controlled Study in Participants With Long COVID-19: The REVIVE Trial (REVIVE)

Chronic Fatigue Syndrome | Long COVID-19 Syndrome

Brazil
University of Chicago

Recruiting

Vasoactive Drugs in Intensive Care Unit

Shock

United States
Yale University
National Center for Complementary and Integrative Health (NCCIH); Brain & Behavior...

Completed

Vitamin D as a Therapeutic Adjunct in the Stimulant Treatment of ADHD

ADHD

United States
University of Chicago

Withdrawn

Turning Dexmedetomidine Into a Powerful Anesthetic That Can be Rapidly and Completely Reversed

Emergence From Anesthesia

United States
St. Justine's Hospital

Completed

Dexmedetomine as Adjuvant for Spinal Anesthesia in Elective Cesarian Sections : a Pilot Study

Analgesia | Dexmedetomidine | Anesthesia, Spinal | Anesthesia, Obstetrical | Analgesics, Opioid | Analgesics, Non-Narcotic | Analgesia, Obstetrical

Canada
Baylor College of Medicine

Completed

Complementary Combination Therapy for Cocaine Dependence

Cocaine Dependence

United States
Eyenovia Inc.

Completed

Safety and Efficacy of Phenylephrine 2.5%-Tropicamide 1% Microdose Ophthalmic Solution for Pupil Dilation (MIST-1)

Mydriasis

United States
Bayer

Completed

A Study to Evaluate Changes in Nasal Airflow of Loratadine/Pseudoephedrine Tablet and Fluticasone Propionate Nasal Spray in Subjects Following Allergen Exposure

Rhinitis, Allergic

Canada
Kyowa Kirin Co., Ltd.

Completed

A Drug Interaction Study of KW-6356 With Midazolam, Caffeine, or Rosuvastatin

Parkinson's Disease

Japan
NYU Langone Health

Completed

Goal-Directed Intraoperative Fluid Management Using FloTrac© Monitoring in High-Risk Neurosurgical Patients

Scoliosis | Surgery | Intracranial Aneurysm | Brain Edema

United States
University Health Network, Toronto

Completed

Nebulized Epoprostenol (FLOLAN) and Phenylephrine on One Lung Ventilation (OLV) (FLOLAN)

Oxygenation During One Lung Ventilation

Canada
GlaxoSmithKline

Withdrawn

An Efficacy and Safety Study of Theraflu Day Powder as Oral Solution for Cold and Flu

Infections, Respiratory Tract
St. Renatus, LLC
Rho, Inc.; Triligent International

Completed

Dose-Ranging Study of Intranasal Kovacaine Mist in Pediatric Subjects

Anesthesia

United States
Sandoz

Completed

To Demonstrate the Relative Bioavailability of Cetirizine Hydrochloride/Pseudoephedrine Hydrochloride 5 mg/120 mg Extended Release (ER) Tablets Under Fed Conditions

Allergies
Tong Lee

Completed

Open-label, Normal Healthy Volunteer Clinical Trial of a Novel Ondansetron Formulation

Healthy

United States
Adams Respiratory Therapeutics

Completed

Phase 4 Study - Mucinex D as Adjunct Therapy

Bronchitis | Acute Respiratory Infection | Rhinosinusitis

United States
Zagazig University

Completed

Suprascapular Nerve Block With Oral Gabapentin For Pain Management In Frozen Shoulder

Pain, Shoulder

Egypt
Dalian Municipal Central Hospital

Recruiting

A Prospective Study of Vasopressor on Cerebral Oxygenation During General Anesthesia

Hypotension Drug-Induced

China
Northwestern University

Recruiting

Potassium Citrate and Crystal Light Lemonade

Kidney Stone

United States
Aristotle University Of Thessaloniki

Completed

Efficacy and Safety of Mydriatic Microdrops Compared With Standard Drops for Retinopathy of Prematurity (ROP) Screening: a Pilot Randomized Clinical Trial

Retinopathy of Prematurity

Greece
Bayer

Completed

Placebo and Active Controlled Study to Assess Efficacy and Tolerability of Aspirin Plus Pseudoephedrine

Common Cold | Pharyngitis

Poland, Slovakia, Italy, United States
The University of Texas Health Science Center,...
National Institute on Drug Abuse (NIDA)

Completed

Effectiveness of Modafinil and D-amphetamine in Treating Cocaine Dependent Individuals

Cocaine-Related Disorders

United States
Crystal A. Gadegbeku
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); University... and other collaborators

Completed

Pilot Study On The Role Of Nitric Oxide In Alpha 1-Adrenergic Vasoreactivity

Blood Pressure

United States
Kasr El Aini Hospital

Completed

Phenylephrine and Noradrenaline for Post Spinal Anesthesia Hypotension

Adverse Anesthesia Outcome
Sandoz

Completed

To Demonstrate the Relative Bioavailability of Cetirizine Hydrochloride/Pseudoephedrine Hydrochloride 5 mg/120 mg Extended Release (ER) Tablets Under Fasting Conditions

Allergies
Ache Laboratorios Farmaceuticos S.A.

Completed

Efficacy and Safety of Combination of Brompheniramine and Phenylephrine for the Symptoms Relief of Rhinitis

Rhinitis | Nasal Congestion and Inflammations

Brazil
The University of Texas Health Science Center,...
Memorial Hermann Hospital

Terminated

Caffeine in Children With Obstructive Sleep Apnea, Dose Response Study

Obstructive Sleep Apnea | Enlargement of Tonsil or Adenoid

United States
Novartis

Withdrawn

Safety of Phenylephrine Hydrochloride, Acetaminophen, Dimethindene Maleate Compared to Phenylephrine Hydrochloride Alone in Healthy Volunteers

Blood Pressure | Arrhythmias | Heart Rate

Brazil
King Faisal Specialist Hospital & Research Center

Completed

The Placebo Effect May Involve Modulating Drug Bioavailability

Pharmacokinetics | Placebo Effect | Drug Half Life

Saudi Arabia
Medical University of Vienna

Completed

Role of Nitric Oxide in Optic Nerve Head Blood Flow Regulation During Isometric Exercise in Healthy Humans

Healthy

Austria
Hospices Civils de Lyon

Unknown

Comparison of Three Different Strategies to Prevent Propofol Induced Pain During Infusion

Induction of Total Intravenous General Anesthesia

France
National Institute of Allergy and Infectious Diseases...

Completed

Evaluating the Efficacy and Safety of Dolutegravir-Containing Versus Efavirenz-Containing Antiretroviral Therapy Regimens in HIV-1-Infected Pregnant Women and Their Infants (VESTED)

HIV Infections

United States, South Africa, Thailand, Botswana, Brazil, Tanzania, Zimbabwe, India, Uganda
Medical College of Wisconsin

Completed

Ketamine Infusion Therapy for the Management of Acute Pain in Adult Rib Fracture Patients

Wounds and Injuries | Rib Fractures

United States
Wake Forest University Health Sciences

Completed

Systemic Steroids for Peripheral Nerve Blocks

Osteoarthritis, Hip

United States
Ankara University

Completed

The Simultaneous Use of Supraclavicular and Distal Blocks

Anaesthesia | Nerve Block | Orthopaedic Disorders

Turkey
Göteborg University

Recruiting

Effects of an Opioid Free/Sparing Care Pathway for Patients Undergoing Obesity Surgery (OS-PCC)

Obesity | Pain, Postoperative

Sweden
University of Miami

Active, not recruiting

Rituximab and Combination Chemotherapy in Treating Patients With Previously Untreated Mantle Cell Lymphoma

Mantle-Cell Lymphoma

United States
TG Therapeutics, Inc.
SCRI Development Innovations, LLC

Completed

TGR-1202 Alone and in Combination With Either Nab-paclitaxel + Gemcitabine or With FOLFOX in Patients With Select Relapsed or Refractory Solid Tumors

Gastric Cancer | Colorectal Cancer | Pancreatic Cancer | Esophageal Cancer | Rectal Cancer | Gastrointestinal Stromal Tumor (GIST)

United States
Cingulate Therapeutics

Recruiting

Phase 3 Efficacy and Safety Laboratory Classroom Study in Pediatrics (6-12) With ADHD Using CTx-1301

ADHD | Attention Deficit Hyperactivity Disorder | Attention Deficit Disorder With Hyperactivity | ADHD - Combined Type | Attention Deficit Hyperactivity Disorder Combined | Attention Deficit Hyper Activity | Attention-deficit Hyperactivity

United States
University of Missouri-Columbia

Recruiting

Sex Disparities in Hypoxic Sympatholysis and Impact of Obesity

Healthy | Obesity | Vasodilation | Vasoconstriction

United States

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