Search clinical trials for: Varenicline free base solution

Total 584 results

Pfizer

Completed

A Study Evaluating The Absorption Of Varenicline Into The Body From A Varenicline Solution And A Varenicline Patch Applied To The Skin

Smoking Cessation

United States
Pfizer

Completed

A Single Dose Study Investigating the Absorption and Elimination as Well as the Tolerability of Varenicline Transdermal Delivery System (e.g., a Patch) as Compared to Oral Varenicline in Adult Smokers.

Smoking Cessation

United States
Oyster Point Pharma, Inc.

Completed

Evaluating Relative Bioavailability of OC-01 (Varenicline) Nasal Spray as Compared to Orally Administered Varenicline

Healthy Subjects

United States
Pfizer

Completed

A Study Evaluating The Absorption Of Varenicline Into The Body From A Varenicline Patch Applied To The Skin

Smoking Cessation

Belgium
Pfizer

Completed

A Study Evaluating the Absorption Of Varenicline Through The Skin Following Once Daily Application Of A Patch For 14 Days

Smoking Cessation

United States
Ji Xing Pharmaceuticals (Shanghai) Co., Ltd.
Oyster Point Pharma, Inc.

Completed

Clinical Trial to Evaluate the Efficacy and Safety of OC-01 (Varenicline) Nasal Spray on Signs and Symptoms of Dry Eye Disease

Dry Eye Disease

China
Ji Xing Pharmaceuticals (Shanghai) Co., Ltd.
Oyster Point Pharma, Inc.

Completed

Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of OC-01 in Adult Chinese With Dry Eye Disease

Dry Eye Disease

China
Santen Oy

Completed

A Study to Evaluate Pharmacokinetics of Tafluprost Ophthalmic Solution (0.0015%) in Pediatric Patients With Glaucoma or Ocular Hypertension

Ocular Hypertension | Glaucoma

United Kingdom, United States
Alcon Research

Completed

Clinical Characterization of an Investigational Frequent Replacement Daily Wear Silicone Hydrogel Sphere Contact Lens

Refractive Errors

United States
Galapagos NV

Completed

Oral Bioavailability of Two Solid Formulations of GLPG0259.

Healthy

Belgium
Alcon Research

Completed

Lens Wearing Experience and Biocompatibility of a Multi-Purpose Disinfecting Solution (MPDS)

Healthy

United States
Stephenson Eye Associates

Recruiting

A Randomized, Controlled, Double-masked, Investigator-initiated Trial to Evaluate Tear Film Quality and Stability in Subjects With Dry Eye Disease Using OC-01 (Varenicline Solution) Nasal Spray 0.03 mg as Compared to Vehicle Control Nasal Spray (TSUNAMI)

Dry Eye Disease

United States
Alcon Research

Completed

Subjective Comfort With Multipurpose Care Solutions in Soft Contact Lens Wearers

Refractive Error | Astigmatism | Myopia

United States
Alcon Research

Completed

Systane® Complete Preservative Free Lubricant Eye Drops

Dry Eye

Canada
Alcon Research

Completed

A Multi-Center Investigation of Patient Acceptability of OPTI-FREE RepleniSH® Multi-Purpose Disinfecting Solution (MPDS)

Myopia

United States
Chulalongkorn University

Completed

Comparison of Cardiac Index and Cardiac Output Effect During Maintenance Hemodialysis Between Acetate-Free and Acetate-Based Online Hemodiafiltration

End-stage Renal Disease

Thailand
University of Alabama at Birmingham
U.S. Department of Education

Completed

Falls-based Training for Walking Post-Stroke (FBT)

Cerebral Hemiplegia
Abbott Medical Optics

Completed

Comparison of a New Abbott Medical Optics (AMO) Multi-Purpose Solution (MPS) to Existing Contact Lens Regimens

Normal Contact Lens Wearers

Canada
Fred Hutchinson Cancer Center
Kenya Medical Research Institute; Jhpiego

Recruiting

Pharmacy-based PrEP Delivery in Kenya

Hiv

Kenya
Vastra Gotaland Region

Completed

A Randomized Controlled Study Comparing Priming Solution Containing Crystalloid or Packed Red Blood Cells in Patients Treated With Isolated Limb Perfusion. (ILP-Prime)

Melanoma | Sarcoma

Sweden
Alcon, a Novartis Company

Completed

OPTI-FREE® PureMoist® for Presbyopic Contact Lens Wearers

Presbyopia
Ottawa Hospital Research Institute
Heart and Stroke Foundation of Ontario

Completed

Sympathetic Activity in Patients With End-stage Renal Disease on Peritoneal Dialysis (SAPD)

End-stage Renal Disease (ESRD) | Kidney Disease

Canada
Cornea and Laser Eye Institute

Recruiting

Accelerated Corneal Collagen Crosslinking for Keratoconus and Ectasia Using Pulse or Continuous UV-A Light

Keratoconus | Corneal Ectasia

United States
Alcon Research

Completed

Comparison of 3 Novel Contact Lens Solutions on the Basal Lamina

Contact Lens Solution

United States
Idorsia Pharmaceuticals Ltd.

Completed

A Study to Investigate the Safety, Tolerability, Pharmacokinetics (PK), and Pharmacodynamics (PD) of ACT-541468 in Healthy Young Adults and Elderly Subjects

Healthy Subjects

Netherlands
Alcon Research

Completed

Clinical Outcomes Following Treatment With Systane® Balance in Dry Eye Subjects

Dry Eye
Oyster Point Pharma, Inc.

Completed

Clinical Trial to Evaluate the Efficacy of OC-02 Nasal Spray on Signs and Symptoms of Dry Eye Disease (The PEARL Study)

Dry Eye Disease

United States
Alcon Research

Recruiting

Systane® Ultra Preservative Free Lubricant Eye Drops

Dry Eye

Canada
Sterna Biologicals GmbH & Co. KG

Completed

Efficacy, Pharmacokinetics, Tolerability, Safety of SB012 Intrarectally Applied in Active Ulcerative Colitis Patients (SECURE)

Colitis, Ulcerative

Germany
AnHeart Therapeutics Inc.

Completed

A First-in-human Study to Evaluate the Safety, Tolerability and Pharmacokinetics of DS-6051b

Solid Tumors

United States
Alcon Research

Recruiting

Systane® Hydration PF and Systane® Hydration Preserved

Dry Eye

Canada
Tecnoquimicas

Recruiting

Management of the Ocular Surface With Preservative-Free Lubricants in Patients With Dry Eye

Dry Eye Disease

Colombia
Mead Johnson Nutrition

Completed

Clinical Effectiveness and Safety of a Novel Oral Rehydration Solution

Gastroenteritis Acute

Thailand
University of Pennsylvania
Oyster Point Pharma, Inc.

Completed

Nasal Spray Study in Sjogren's Dry Eye Disease

Dry Eye | Sjogren's Syndrome

United States
Alcon Research

Completed

Clinical Characterization of an Investigational Soft Silicone Hydrogel Contact Lens

Refractive Errors

United States
Massachusetts Eye and Ear Infirmary
University of Iowa; Alcon Research

Completed

Effect of Contact Lens Wear on Immune Cell Density and Morphology of the Ocular Surface

Refractive Error | Myopia

United States
Yale University
National Institute on Drug Abuse (NIDA)

Completed

Incentive-based Intervention for Smoking Cessation and Prevention in High Schools (Rise Above)

Tobacco Prevention and Cessation

United States
Laboratorios Sophia S.A de C.V.

Completed

Safety and Tolerability of PRO-087 Versus Xyel Ofteno® and Systane Ultra®, on the Ocular Surface of Healthy Subjects (PRO-087/I)

Dry Eye Syndromes | Lubricant Allergy | Tear Disorder

Mexico
Cadex Genomics

Completed

Development of a Cell Free DNA Assay as a Biomarker for Predicting Early Non-response to Therapy in Metastatic Cancer

Metastatic Colorectal Cancer | Metastatic Breast Cancer | Metastatic Non-Small Cell Lung Carcinoma

United States, Canada
Cairo University

Not yet recruiting

HEMA-free Universal Adhesives for Restoring Non-carious Cervical Lesions

Universal Adhesive
University of Molise
Azienda Ospedaliera Universitaria Mater Domini, Catanzaro; Ospedale Santa Croce-Carle... and other collaborators

Completed

Effectiveness of Liposomial Ozonized-Oil for Cataract Surgery

Ocular Infections

Italy
Alcon Research

Completed

Subjective Comfort With Multipurpose and Hydrogen Peroxide Lens Care Solutions in Soft Contact Lens Wearers

Contact Lens Wear
SRI International
National Cancer Institute (NCI)

Completed

Varenicline Tartrate With Telephone-Based Counseling and/or Internet-Based Counseling in Helping Adults Stop Smoking

Unspecified Adult Solid Tumor, Protocol Specific

United States
Spektrum Center of Clinical Ophthalmology
Wrocław University of Science and Technology

Active, not recruiting

Eye Surface Properties After Using Dexamethasone Drops With and Without Preservatives in Patients After Cataract Surgery (EyeSurface)

Healing Wound | Cataract | Surgical Injury

Poland
Yonsei University

Completed

Clinical Effects of Diquas-S for Patients With Dry Eye After Cataract Surgery

Dry Eye | Cataract Surgery

Korea, Republic of
University of Oklahoma

Recruiting

Sensory-Play Based (SenPlay) Intervention for Young Children With or At Risk for ADHD

Attention Deficit Hyperactivity Disorder

United States
Mead Johnson Nutrition

Completed

The Evaluation of Infant Formulas Fed to Infants With Common Feeding Problems

Common Infant Feeding Problems

United States, Canada
Hasselt University

Unknown

Nature-based Solutions for Work-related Stress

Stress, Psychological

Belgium
Association for Innovation and Biomedical Research...
European Vision Institute Clinical Research Network

Completed

Intraocular Pressure and Tolerability Study of Preservative-free Prostaglandins (Bimatoprost and Latanoprost) on Glaucoma and Ocular Hypertension: European, Multicentric, Investigator-led, Single Masked Study (SPORT)

Ocular Hypertension | Glaucoma

United Kingdom, Switzerland, Belgium, Italy, Portugal, Austria
Hasselt University

Recruiting

The Impact of Green Spaces on the General Well-being and Stress of Students

Stress | Psychological | Cardiovascular | Neurocognition

Belgium

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