Search clinical trials for: Vehicle saline as placebo

Total 2986 results

Cara Therapeutics, Inc.

Terminated

Study to Evaluate the Efficacy and Safety of Oral Difelikefalin as Adjunct Therapy to a Topical Corticosteroid for Moderate to Severe Pruritus in Subjects With Atopic Dermatitis (KIND-1)

Pruritus | Atopic Dermatitis

United States
Botanix Pharmaceuticals

Completed

A Safety, Tolerability and Preliminary Efficacy Study of BBI-4000 Gel in Subjects With Palmar Hyperhidrosis

Hyperhidrosis

United States
University of California, Davis

Completed

Topical Acetyl Hexapeptide-8 and the Cosmetic Appearance of Oily Skin

Oily Skin

United States
Dompé Farmaceutici S.p.A

Completed

Evaluation of Efficacy of 20 µg/ml rhNGF New Formulation (With Anti-oxidant) in Patients With Stage 2 and 3 NK

Neurotrophic Keratitis

United States
NoNO Inc.
University of Calgary

Completed

Safety and Efficacy of Nerinetide (NA-1) in Subjects Undergoing Endovascular Thrombectomy for Stroke (ESCAPE-NA1)

Stroke, Acute

United States, Ireland, Korea, Republic of, Canada, Sweden, Germany, United Kingdom, Australia
Actavis Inc.

Completed

An Equivalence Study of Generic Ingenol Mebutate Gel 0.015% and Picato Gel 0.015% in Subjects With Actinic Keratosis

ACTINIC KERATOSIS

United States
University of Utah
Novartis Pharmaceuticals

Completed

A Pilot Study of the Treatment of Eosinophilic Esophagitis With Omalizumab

Esophagitis

United States
University Health Network, Toronto

Completed

Safety of Tranexamic Acid in Reducing Bleeding in Adults Undergoing Spinal Surgery

Spine Surgery

Canada
University of Alabama at Birmingham

Completed

Intranasal Oxytocin for the Treatment of Pain Associated With Interstitial Cystitis

Interstitial Cystitis

United States
Boston Medical Group

Recruiting

Effectiveness and Safety of TENS Therapy for Premature Ejaculation (TENSPE2)

Premature Ejaculation | TEN | Sex Disorder

Mexico
ADARx Pharmaceuticals, Inc.

Recruiting

Safety, Tolerability, PK, PD of ADX-324 in Healthy Volunteers and Hereditary Angioedema Patients

Hereditary Angioedema

Australia
Revimmune
C.R.O. ReSolution Latin America S.A.

Terminated

InterLeukin-7 to Improve Clinical Outcomes in Lymphopenic pAtients With COVID-19 Infection (Brazil Cohort) (ILIAD-7-BRA)

COVID-19 | Lymphocytopenia

Brazil
Revimmune
M.D. Anderson Cancer Center; Memorial Sloan Kettering Cancer Center; Cancer Research... and other collaborators

Terminated

InterLeukin-7 to Improve Clinical Outcomes in Lymphopenic Patients With COVID-19 Infection ( ILIAD-7-US-O ) (ILIAD-7-US-O)

COVID-19 | Lymphocytopenia

United States
Ben-Gurion University of the Negev

Terminated

Intraarticular Ozone Therapy for Pain Control in Osteoarthritis of the Knee

Osteoarthritis of the Knee

Israel
Barry Borlaug

Completed

Acute Effects of Inorganic Nitrite on Cardiovascular Hemodynamics in Heart Failure With Preserved Ejection Fraction

Heart Disease | Pulmonary Hypertension | Heart Failure With Preserved Ejection Fraction | Exercise Intolerance

United States
Hadassah Medical Organization

Completed

Beta Glucosylceramide for Treatment of NASH

Compliance Behavior
Children's Hospital Medical Center, Cincinnati
Johns Hopkins Bloomberg School of Public Health; Bill and Melinda Gates Foundation and other collaborators

Completed

Field Trial of Maternal Influenza Immunization in Asia (Mothers'Gift)

Influenza Human

Nepal
Pfizer

Completed

RIPT of Ibuprofen Topical Gel

Pain

United States
University of Baghdad

Recruiting

Evaluating the Efficacy of Resveratrol Containing Mouthwash as Adjunct Treatment Periodontitis: (resveratrol)

Periodontitis

Iraq
ADARx Pharmaceuticals, Inc.
ADARx Australia Pty Ltd

Recruiting

Safety, Tolerability, PK and PD of ADX-038 in HV and Paroxysmal Nocturnal Hemoglobinuria (PNH) Patients (PNH)

Paroxysmal Nocturnal Hemoglobinuria (PNH)

Australia
GeneOne Life Science, Inc.

Not yet recruiting

GLS-1200 Topical Nasal Spray to Prevent Sinusitis After Endoscopic Sinus Surgery

Sinusitis Chronic

United States
MitoImmune Therapeutics

Active, not recruiting

Evaluate the Safety and Efficacy for Oral Mucositis Prevention of MIT-001 in Auto HSCT (Capella)

Lymphoma | Multiple Myeloma | Oral Mucositis | Hematologic Cancer

Korea, Republic of
Merck Sharp & Dohme LLC

Completed

Single Dose Study of MK-2060 to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics in Older Japanese Participants on Dialysis (MK-2060-012)

Kidney Failure, Chronic | End-Stage Renal Disease (ESRD) | End-Stage Kidney Disease (ESKD)

Japan
Swedish Orphan Biovitrum

Completed

A Study to Evaluate Emapalumab in Japanese Healthy Volunteers.

Rare Diseases

Japan
Revimmune
University Hospital, Limoges; Amarex Clinical Research

Terminated

InterLeukin-7 to Improve Clinical Outcomes in Lymphopenic pAtients With COVID-19 Infection FR BL Cohort (ILIAD-7-FR)

COVID-19 | Lymphocytopenia

France
Emma Guttman

Completed

A Pilot Study of Tralokinumab in Subjects With Moderate to Severe Alopecia Areata

Alopecia Areata

United States
Columbia University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Terminated

Leptin in Human Energy and Neuroendocrine Homeostasis

Obesity | Weight Loss

United States
Tianjin Medical University Cancer Institute and...

Unknown

Monosialotetrahexosylganglioside Sodium Injection for Prevention Neurotoxicity of mFOLFOX 6 in mCRC

Colorectal Cancer

China
Pacira Pharmaceuticals, Inc

Completed

Study of Pain Control in Hemorrhoidectomy

Hemorrhoid

Poland
University of British Columbia

Completed

Mannitol Cream for Post Herpetic Neuralgia (MannitolPHN)

Neuralgia, Postherpetic

Canada
Santen Inc.
ActualEyes Inc.

Active, not recruiting

A Multicenter Study Assessing the Efficacy and Safety of STN1010904 Ophthalmic Suspension 0.03% and 0.1% Compared With Vehicle in Subjects With Fuchs Endothelial Corneal Dystrophy (FECD) (PHANTOM)

Fuchs Endothelial Corneal Dystrophy

United States, France, India
Reistone Biopharma Company Limited

Terminated

Assess the Efficacy and Safety of SHR0302 Ointment in Adult Patients With Vitiligo

Vitiligo

China
Biosplice Therapeutics, Inc.

Completed

A Study Utilizing Patient-Reported Outcomes to Evaluate the Safety and Efficacy of Lorecivivint (SM04690) for the Treatment of Moderately to Severely Symptomatic Knee Osteoarthritis (STRIDES-1)

Knee Osteoarthritis

United States
Healthpoint

Terminated

Safety and Efficacy Trial of HP802-247 in the Treatment of Chronic Venous Leg Ulcers

Ulcer | Venous Ulcer | Venous Stasis Ulcer

Germany, Poland, Belgium, Czech Republic, Hungary
Janssen Biotech, Inc.

Terminated

A Multicenter Trial Comparing REMICADE (Infliximab) and Placebo in the Prevention of Recurrence in Crohn's Disease (CD) Patients Undergoing Surgical Resection Who Are at an Increased Risk of Recurrence

Crohn's Disease

United States, France, United Kingdom, Germany, Belgium, Australia, Israel, Canada, Netherlands, New Zealand, Czech Republic, Austria, Poland, Hungary
Xequel Bio, Inc.

Completed

A Study of Granexin® Gel for the Reduction of Scar Formation in Surgical Wounds Following Bilateral Anchor Incision Breast Surgery

Scar | Breast Reconstruction | Scarring | Mammoplasty

United States
Parion Sciences

Completed

An Evaluation of the Impact of a Single Dose of P-552 on Oral Mucosal Wetness

Sjogren's Syndrome | Xerostomia

United States
Johns Hopkins University

Recruiting

Peripheral Modulation of Muscle Stiffness and Spasticity

Muscle Spasticity

United States
University of Malaya

Completed

Trial on The Efficacy of Hypertonic Saline on Non-CF CSLD.

Bronchiectasis

Malaysia
Revimmune
Washington University School of Medicine; Amarex Clinical Research

Terminated

InterLeukin-7 to Improve Clinical Outcomes in Lymphopenic pAtients With COVID-19 Infection ( ILIAD-7-US-I ) (ILIAD-7-US-I)

COVID-19 | Lymphocytopenia

United States
University of California, Los Angeles

Withdrawn

Exogenous Sodium Lactate Infusion in Traumatic Brain Injury (ELI-TBI) (ELI-TBI)

Brain Injuries, Traumatic

United States
Erasme University Hospital

Completed

Hemin to Prevent Post-ERCP (Endoscopic Retrograde Cholangiopancreatography) Acute Pancreatitis

Post-ERCP Acute Pancreatitis

Taiwan, Belgium
AstraZeneca
Covance; ICON plc; PHT Corporation

Terminated

Assessment of the Safety, Tolerability and Efficacy of MEDI8968 in Subjects With Moderate to Severe Hidradenitis Suppurativa

Hidradenitis Suppurativa

United States
Pacira Pharmaceuticals, Inc

Completed

Study of Postoperative Analgesia in Bunionectomy

Bunion | Hallux Valgus

United States
Biogen

Terminated

A Study To Evaluate The Safety And Efficacy Of PF-04958242 In Subjects With Cognitive Impairment Associated With Schizophrenia (CIAS)

Cognitive Impairment Associated With Schizophrenia (CIAS)

United States
Montefiore Medical Center

Completed

IV Acetaminophen for Acute Post Operative Pain in C-Section Patients

Post-operative Pain

United States
The Hospital for Sick Children

Completed

A Randomized-Controlled Trial of Inhaled Hypertonic Saline (7%) to Evaluate the Lung Clearance Index

Cystic Fibrosis

Canada
GemVax & Kael

Completed

A Phase II Clinical Trial to Evaluate the Efficacy and Safety of GV1001 in Patients With BPH

Benign Prostatic Hyperplasia (BPH)

Korea, Republic of
United Therapeutics

Terminated

A Safety Study of IV Stem Cell-derived Extracellular Vesicles (UNEX-42) in Preterm Neonates at High Risk for BPD

Bronchopulmonary Dysplasia

United States
Biosplice Therapeutics, Inc.
NBCD A/S

Completed

A Study Utilizing Patient-Reported Outcomes to Evaluate the Safety and Efficacy of Lorecivivint (SM04690) for the Treatment of Moderately to Severely Symptomatic Knee Osteoarthritis (STRIDES)

Knee Osteoarthritis

United States

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