Search clinical trials for: Viral Protease Inhibitors

Total 64929 results

Catholic University of the Sacred Heart

Terminated

Switch to Darunavir/r + Maraviroc Quaque Die in Patients With R5 Tropism by Viral DNA Genotyping (GUSTA) (GUSTA)

HIV Infection

Italy
Janssen Research & Development, LLC

Completed

A Study of Darunavir in Combination With Cobicistat or Ritonavir, and Dabigatran Etexilate in Healthy Participants

Healthy

Belgium
The HIV Netherlands Australia Thailand Research...
Bristol-Myers Squibb

Completed

Pharmacokinetic Study of 2 Doses of ATV/r OD + 2 NRTIs in Thai HIV-1 Infected Patients

HIV Infections

Thailand
Foundation for Cardiovascular Research, Zurich
Bristol-Myers Squibb

Completed

Effect of Atazanavir on Endothelial Function in HIV-Infected Patients (ENDOPACT)

HIV Infections | Dyslipidemia

Switzerland
Janssen Korea, Ltd., Korea

Completed

A Post Marketing Survey Study to Evaluate the Safety and Effectiveness of Prezista

Acquired Immune Deficiency Syndrome

Korea, Republic of
ViiV Healthcare
GlaxoSmithKline

Completed

Fosamprenavir Expanded Access

Infection, Human Immunodeficiency Virus

Switzerland
Maastricht Radiation Oncology

Completed

Nelfinavir, a Phase I/Phase II Rectal Cancer Study (Nelfinavir)

Colorectal Cancer | Colorectal Tumors | Colorectal Carcinoma | Neoplasms, Colorectal

Netherlands
Janssen-Cilag International NV

Completed

Treatment Simplification by Darunavir/Ritonavir 800/100 mg Once a Day Versus a Triple Combination Therapy With Darunavir/Ritonavir (MONET)

HIV Infections | Human Immunodeficiency Virus | Acquired Immunodeficiency Syndrome Virus | AIDS Virus

United Kingdom, Belgium, Germany, Spain, Portugal, Israel, Denmark, Russian Federation, Austria, Hungary, Switzerland
Tibotec Pharmaceuticals, Ireland

Completed

Innovation-TiFP4-C101: A Study to Evaluate the Pharmacokinetics of TMC114 and TMC41629 After a Single Oral Dose of 2 Controlled-release Coformulations as Compared to an Immediate-release Coformulation of TMC114/TMC41629

HIV-I
Merck Sharp & Dohme LLC

Completed

A Study of L-735,524 in HIV-Positive Children and Adolescents

HIV Infections

United States
Pfizer

Completed

PF-07321332/Ritonavir and Ritonavir on Dabigatran Study in Healthy Participants

Healthy Participants

United States
Maastricht Radiation Oncology
Maastricht University Medical Center

Completed

Study With Nelfinavir and Combined Radiochemotherapy for Glioblastoma

Glioblastoma

Netherlands
Tibotec Pharmaceuticals, Ireland

Approved for marketing

TMC114-C226: An Early Access Program to Evaluate the Long-term Safety and Tolerability of TMC114 Combined With a Low Dose of Ritonavir (TMC114/r) With Other Antiretrovirals, for HIV-1 Infected Patients Who Have Failed Multiple Antiretroviral Regimens.

HIV Infections

United States, Belgium, Germany, Taiwan, Spain, Switzerland, Mexico, Slovenia, Malaysia, Turkey, Canada, Netherlands, Denmark, Greece, Sweden, Russian Federation, Czech Republic, Puerto Rico, Thailand, Hungary, Luxembourg, Venezuela
University of Roma La Sapienza

Unknown

ATAGLU: Study of Glucose Metabolism in HIV Positive Patients That Switch From Another Protease Inhibitor to Atazanavir (ATAGLU)

HIV

Italy
Stanford University
Bristol-Myers Squibb

Completed

Atazanavir or Boosted Atazanavir Substitution for Ritonavir Boosted PI in Patients With Hyperlipidemia

HIV Infections | Hyperlipidemia

United States
Tibotec Pharmaceuticals, Ireland

Completed

TMC114-C213: A Phase II Randomized, Controlled, Partially Blinded Trial to Investigate Dose-response of TMC114/RTV in 3-class-experienced HIV-1 Infected Patients, Followed by an Open-label Period on the Recommended Dose of TMC114/RTV.

HIV
Fundación FLS de Lucha Contra el Sida, las Enfermedades...

Completed

Multicentre Study To Assess Changes In Bone Mineral Density Of The Switch From Protease Inhibitors To Dolutegravir In HIV-1-Infected Subjects With Low Bone Mineral Density

HIV-1 Infection

Spain
Phoenix Children's Hospital
Bristol-Myers Squibb

Completed

Equivalence of Boosted Atazanavir Based Regimens and Currently Effective HAART Regimens

HIV Infections | Pediatric HIV

United States
Bristol-Myers Squibb

Completed

Atazanavir Twice Daily

HIV Infections | Protease Inhibitor

United States
National Institute of Allergy and Infectious Diseases...

Completed

The Addition of Indinavir to Anti-HIV Treatment in HIV-Infected Patients

HIV Infections

United States
Tibotec Pharmaceuticals, Ireland

Completed

TMC114-C214: Trial of TMC114 Administered With Low Dose Ritonavir (RTV) in HIV-1 Infected Treatment Experienced Patients

HIV Infection

United States, Australia, France, United Kingdom, Belgium, Germany, Spain, Argentina, Chile, Mexico, Portugal, Malaysia, Panama, South Africa, Canada, Netherlands, Brazil, Puerto Rico, Austria, Russian Federation, Thailand, Hungary, Denmar... and more
Merck Sharp & Dohme LLC

Completed

A Study on the Safety and Effectiveness of L-756423 Plus Indinavir in HIV-Positive Patients Who Have Previously Taken Indinavir

HIV Infections

United States
National Cancer Institute (NCI)

Completed

A Phase I Trial of Nelfinavir (Viracept ) in Adults With Solid Tumors

Solid Tumors

United States
University of Colorado, Denver
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Genetics and HIV-1 Protease Inhibitors

HIV

United States
Brigham and Women's Hospital

Completed

Atazanavir and Endothelial Function in Older HIV Patients

HIV

United States
Mayo Clinic

Terminated

Cardiopulmonary Bypass-Induced Lymphocytopenia and the Potential Effects of Protease Inhibitor

Cardiopulmonary Bypass

United States
Imperial College London

Completed

The Maraviroc Darunavir/Ritonavir Once Daily Pharmacokinetic Study

HIV

United Kingdom
ViiV Healthcare
GlaxoSmithKline

Completed

Drug-drug Interaction (DDI) Rifabutin

Infection, Human Immunodeficiency Virus

United States
Garden State Infectious Disease Associates, PA
GlaxoSmithKline

Completed

An Interaction Study to Assess Drug Levels in Healthy Adult Subjects

Healthy

United States
National Institute of Allergy and Infectious Diseases...

Withdrawn

A Randomized Trial of L-735,524, An Inhibitor of the HIV Protease Enzyme, and Interleukin-2 in Persons Infected With HIV (NOTE: Only For Patients Who Previously Completed NIAID 93 CC-113)

HIV Infections
National Cancer Institute (NCI)

Completed

A Phase I /II Study of the Protease Inhibitor Indinavir (MK-0639) in Children With HIV Infection

HIV Infections | Acquired Immunodeficiency Syndrome

United States
Oxford University Hospitals NHS Trust

Withdrawn

Radical Lung Radiotherapy Plus Nelfinavir (NelfLung)

Lung Cancer

United Kingdom
Bristol-Myers Squibb

No longer available

Atazanavir for HIV Infected Individuals: An Early Access Program

HIV Infections

United States, Puerto Rico
Abramson Cancer Center of the University of Pennsylvania

Completed

A Study of Nelfinavir Added to Cisplatin Chemotherapy Concurrent With Pelvic Radiation for Locally Advanced Cervical Cancer (II-IVA)

Uterine Cervix Cancer

United States
The HIV Netherlands Australia Thailand Research...
amfAR, The Foundation for AIDS Research; National Health Security Office, Thailand and other collaborators

Completed

Atazavanir/Ritonavir-based HAART in Children

HIV

Thailand
Tibotec Pharmaceuticals, Ireland

Completed

TMC114-C211: Trial of an Investigational Protease Inhibitor TMC114 With Ritonavir ("TMC114/r") in HIV-1 Infected Patients Who Have Never Been Treated With Antiretroviral Medications.

HIV

United States, France, United Kingdom, Germany, Taiwan, Spain, Belgium, Chile, Costa Rica, Panama, South Africa, Canada, Greece, Singapore, Argentina, Mexico, Puerto Rico, Austria, Russian Federation, Thailand, Australia, Denmark, S... and more
Radboud University Medical Center
Dutch Diabetes Research Foundation

Completed

Effects of Atazanavir Treatment on Type 2 Diabetes Mellitus Related Endothelial Dysfunction (DM2ATV)

Type 2 Diabetes Mellitus Related Endothelial Dysfunction

Netherlands
Boehringer Ingelheim

Completed

Tipranavir/Ritonavir vs. Genotypically Defined Protease Inhibitor/Ritonavir in HIV Patients (RESIST-2)

HIV Infections

Argentina, Austria, Belgium, Brazil, Denmark, France, Germany, Greece, Ireland, Italy, Mexico, Netherlands, Portugal, Spain, Sweden, Switzerland, United Kingdom
ViiV Healthcare
GlaxoSmithKline

Completed

48-Week Study Of GW433908 And Ritonavir Or GW433908 Alone, Twice Daily In Pediatric Patients With HIV Infection

Infection, Human Immunodeficiency Virus I

United States, Spain, Canada, Russian Federation, Romania, Belgium, South Africa
Geropharm

Completed

Bioequivalence Study of GP30101 800 mg (GEROPHARM) Versus PREZISTA® 800 mg ("Jonson&Jonson", Russia)

Bioequivalence

Russian Federation
Dartmouth-Hitchcock Medical Center

Withdrawn

Dose Escalation Study of Nelfinavir Plus MLN9708 in Patients With Advanced Solid Tumors or Lymphoma

Neoplasms | Lymphoma

United States
Janssen Research & Development, LLC

Completed

A Study to Assess the Acceptability of the Darunavir/Cobicistat (DRV/COBI) Fixed-dose Combination (FDC) Tablet in Human Immunodeficiency Virus (HIV)-1 Infected Children

Human Immunodeficiency Virus (HIV)

United States, Spain, South Africa
Bristol-Myers Squibb

Terminated

A Comparison of Atazanavir and Nelfinavir, Each in Combination With 2 NRTIs, in Patients Who Have Failed Treatments Without a Protease Inhibitor

HIV Infections

United States, Mexico, Canada, Puerto Rico, Thailand
National Institute of Allergy and Infectious Diseases...
AIDS Clinical Trials Group

Completed

Optimizing Treatment for Treatment-Experienced, HIV-Infected People

HIV Infections

United States, Puerto Rico
French National Agency for Research on AIDS and...

Terminated

Study Evaluating the Impact on Fat Distribution of Nucleoside Reverse Transcriptase Inhibitor (NRTI)-Sparing Regimens in Antiretroviral Experienced Patients With Lipoatrophy

HIV Infections | HIV Lipodystrophy Syndrome

France
Neosil, Inc.

Unknown

Dose-Ranging Efficacy Study of Topical NEOSH101 to Treat Male Pattern Hair Loss

Androgenetic Alopecia

Germany
Neosil, Inc.

Completed

Efficacy Study of Topical NEOSH101 to Treat Male Pattern Hair Loss

Androgenetic Alopecia

Germany
Institut de Médecine et d'Epidémiologie Appliquée...

Completed

Evaluation of the Efficacy and Safety Between Two Antiretroviral Regimens, in HIV-1-infected Treatment-naïve Subjects With Low CD4 Counts (DATA)

HIV-1 Infection | Immunosuppression-related Infectious Disease

France
Radboud University Medical Center

Completed

The Effects of Atazanavir-induced Hyperbilirubinemia During Human Endotoxemia

Sepsis | Inflammation | Endotoxemia | Multi Organ Dysfunction Syndrome

Netherlands
Merck Sharp & Dohme LLC

Completed

Safety and Effectiveness of Giving Indinavir and Nelfinavir to HIV-Infected Patients

HIV Infections

United States

Search clinical trials for: Viral Protease Inhibitors

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