Search clinical trials for: Vonoprazan Placebo

Total 53792 results

Phathom Pharmaceuticals, Inc.

Completed

A Study to Evaluate the Efficacy and Safety of Vonoprazan Compared to Placebo in Participants With Symptomatic Non-Erosive Gastroesophageal Reflux Disease

Heartburn | Non-Erosive Gastro-Esophageal Reflux Disease

United States
Phathom Pharmaceuticals, Inc.

Completed

A Study to Evaluate the Efficacy and Safety of Vonoprazan Compared to Placebo for Relief of Heartburn in Participants With Symptomatic Non-Erosive Gastroesophageal Reflux Disease (NERD)

Heartburn | Non-Erosive Gastro-Esophageal Reflux Disease

United States
Takeda

Completed

Vonoprazan Study of Investigating the Effect on Sleep Disturbance Associated With Reflux Esophagitis- Exploratory Evaluation (VISTAEXE)

Reflux Esophagitis

Japan
Phathom Pharmaceuticals, Inc.

Completed

A Study to Determine the Bioavailability of Vonoprazan Sprinkle Capsules on Pudding or on Applesauce Relative to a Vonoprazan Tablet in Healthy Participants

Healthy Volunteers

United States
Phathom Pharmaceuticals, Inc.

Recruiting

A Study to Evaluate Vonoprazan Concentrations in Breast Milk of Healthy Lactating Women Receiving Vonoprazan 20 mg Once Daily

Helicobacter Pylori Infection | Heartburn | Erosive Esophagitis | Symptomatic Nonerosive Gasroesophageal Reflux Disease

United States
Phathom Pharmaceuticals, Inc.

Completed

A Study to Evaluate Vonoprazan in Children Who Have Symptomatic Gastroesophageal Reflux Disease

Gastroesophageal Reflux Disease

United States
Phathom Pharmaceuticals, Inc.

Completed

A Study to Evaluate the Pharmacokinetics, Pharmacodynamics and Safety of Vonoprazan in Adolescents With Symptomatic Gastroesophageal Reflux Disease

Gastroesophageal Reflux

United States
Takeda

Completed

Efficacy and Safety of Vonoprazan Compared to Lansoprazole in the Maintenance Treatment of Erosive Esophagitis

Erosive Esophagitis

China, Taiwan, Korea, Republic of, Malaysia
Takeda

Completed

Special Drug Use Surveillance of Vonoprazan for "Maintenance Therapy of Reflux Esophagitis: Long-term Use"

Reflux Esophagitis

Japan
Takeda

Completed

Efficacy and Safety of Oral Once-Daily Vonoprazan (TAK-438) in Participants With Erosive Esophagitis

Erosive Esophagitis

China, Taiwan, Korea, Republic of, Malaysia
Takeda

Completed

Drug Use Surveillance of Vonoprazan for "Gastric Ulcer, Duodenal Ulcer, and Reflux Esophagitis"

Gastric Ulcer, Duodenal Ulcer, and Reflux Esophagitis

Japan
The First Affiliated Hospital of Nanchang University

Active, not recruiting

Helicobacter Pylori and Lacidophilin Tablets in Combination With Vonorazan Dual Therapy

Helicobacter Pylori Infection

China
Nanjing First Hospital, Nanjing Medical University

Not yet recruiting

Dual Therapy With Vonoprazan Plus Amoxicillin or Doxycycline Versus Bismuth Quadruple Therapy for Helicobacter Pylori Eradication:A Prospective, Multicenter, Open-label Randomized Controlled Study.

Helicobacter Pylori Infection
Alexandria University

Completed

Vonoprazan Efficacy to Prevent Post Variceal Band Ligation Ulcer

Portal Hypertension | Variceal Hemorrhage | Ulcer Hemorrhage

Egypt
Nanjing First Hospital, Nanjing Medical University

Not yet recruiting

Banxiaxiexin Decoction Combined With Vonoprazan-Amoxicillin Dual Therapy in H.Pylori Eradication

Helicobacter Pylori Infection

China
Sixth Affiliated Hospital, Sun Yat-sen University

Completed

Optimization of Vonoprazan--amoxicillin Dual Therapy for Eradicating Helicobacter Pyloriinfection

Helicobacter Pylori Eradication Rate

China
Xijing Hospital of Digestive Diseases

Recruiting

Standard or Short-course Vonoprazan Non-bismuth Triple Therapy or High-dose Dual Therapy Versus Rabeprazole-bismuth Quadruple Therapy for Primary Helicobacter Pylori Eradication

the Eradication Rates of Helicobacter Pylori

China
Genuine Research Center, Egypt
Hikma Pharma

Completed

Bioequivalence Study of Vonoprazan From Topoprazan 20 mg Tablets (Hikma Pharma, Egypt) Versus Takecab 20 mg Tablets (Takeda Pharmaceutical Co. Ltd., Japan)

Healthy

Egypt
Shandong University
Zaozhuang Municipal Hospital; Zibo Maternal and Child Health Hospital; Binzhou... and other collaborators

Not yet recruiting

Triple Versus Quadruple Therapy for the Eradication of Helicobacter Pylori (SHARE2401)

Helicobacter Pylori Infection
Xijing Hospital of Digestive Diseases

Recruiting

Vonoprazan Hp Dual or Triple Eradication Regimes

Helicobacter Pylori

China
Uayporn Kaosombatwattana

Completed

Efficacy of Vonoprazan Versus Intravenous Proton Pump Inhibitors for Prevention of Rebleeding in High Risk Peptic Ulcers Bleeding After Successful Endoscopic Hemostasis

Peptic Ulcer With Haemorrhage

Thailand
Nanjing First Hospital, Nanjing Medical University

Recruiting

Optimization of Vonoprazan-based Dual Therapy for Helicobacter Pylori

Helicobacter Pylori Infection

China
Nanjing First Hospital, Nanjing Medical University

Recruiting

Efficacy and Safety of Dual Therapy for Helicobacter Pylori Eradication

Helicobacter Pylori Infection

China
Shanghai Jiao Tong University School of Medicine

Completed

High-dose Dual Therapy With Different Administration Frequencies

Helicobacter Pylori Infection

China
Nanjing First Hospital, Nanjing Medical University

Not yet recruiting

The Effect of Probiotics on Gut Microbiotain After Helicobacter Pylori Eradication

Infections | Helicobacter Pylori Infection | Intestinal Bacteria Flora Disturbance

China
Takeda

Completed

Special Drug Use Surveillance of Vonoprazan for "Prevention of Recurrence of Gastric/Duodenal Ulcer in Patients Receiving Non-steroidal Anti-inflammatory Drugs: Long-term Use"

A History of Gastric or Duodenal Ulcers

Japan
Nanjing First Hospital, Nanjing Medical University

Recruiting

Fucoidan Assisted Eradication of Helicobacter Pylori

Helicobacter Pylori Infection | Intestinal Bacteria Flora Disturbance

China
Takeda

Completed

Comparison of Vonoprazan to Esomeprazole in Participants With Symptomatic GERD Who Responded Partially to a High Dose of Proton Pump Inhibitor (PPI)

Gastroesophageal Reflux

Belgium, Bulgaria, Poland, Estonia, United Kingdom, Czechia
Alexandria University

Recruiting

Vonoprazan-based Therapy Versus Standard Regimen for Helicobacter Pylori Infection Management

Helicobacter Pylori Infection

Egypt
Fu Jen Catholic University Hospital

Active, not recruiting

Vonoprazan-Based Triple Therapy in Comparison With Extended Sequential Therapy

Helicobacter Pylori

Taiwan
Phathom Pharmaceuticals, Inc.

Completed

Study to Evaluate the Pharmacokinetics, Pharmacodynamics, and Safety of Vonoprazan and Lansoprazole in Healthy Participants

Healthy Participants

United States
Danish Headache Center
Novartis

Completed

Effect of Levcromakalim in Individuals With Migraine Pretreated With Erenumab (COLLIDE)

Migraine Without Aura

Denmark
Takeda

Completed

Special Drug Use Surveillance of Vonoprazan for "Prevention of Recurrence of Gastric/Duodenal Ulcer in Patients Receiving Low-dose Aspirin: Long-term Use"

Gastric or Duodenal Ulcers

Japan
Takeda

Completed

Vonoprazan Study in Patients With Erosive Esophagitis to Evaluate Long-term Safety

Erosive Esophagitis

Japan
Showa Inan General Hospital

Recruiting

The Need of Revisiting to an Outpatient Clinic After the Prescription of Vonoprazan or Esomeprazole

Gastroesophageal Reflux

Japan
Alimera Sciences

Terminated

Fluocinolone Acetonide Intravitreal Inserts in Geographic Atrophy

Age-Related Macular Degeneration

United States
Phathom Pharmaceuticals, Inc.

Completed

Efficacy and Safety of Vonoprazan Compared to Lansoprazole in Participants With Erosive Esophagitis

Erosive Esophagitis

United States, Poland, Bulgaria, United Kingdom, Czechia, Hungary
Kaohsiung Medical University

Recruiting

Efficacies of Bismuth-amoxicillin-vonoprazan Triple Therapy, Vonoprazan-amoxicillin Dual Therapy and Proton Pump Inhibitor-based Standard Triple Therapy for Hp Eradication

Helicobacter Pylori Eradication

Taiwan
Kaohsiung Medical University

Recruiting

14-day PCAB-based High-dose Dual Therapy and14-day PCAB-based Triple Therapy vs 14-day PPI-based Reverse Hybrid Therapy

Helicobacter Pylori Eradication

Taiwan
St. Luke's Medical Center, Philippines

Terminated

Effectiveness of Vonoprazan vs Omeprazole as Empiric Therapy for Gastroesophageal Reflux Disease (GERD) Patients Without Alarm Features

Gastro Esophageal Reflux | GERD

Philippines
The Third Xiangya Hospital of Central South University
The Second People's Hospital of Huaihua; Yueyang Hospital of Traditional Chinese...

Completed

Esomeprazole/Vonoprazan Combined With High-dose Amoxicillin Dual Therapy for Primary Eradication of Helicobacter Pylori Infection

Helicobacter Pylori Infection

China
Takeda

Completed

Comparison of TAK-438 (Vonoprazan) to Lansoprazole in the Treatment of Duodenal Ulcer Participants With or Without Helicobacter Pylori Infection

Duodenal Ulcer

Taiwan, China, Korea, Republic of, Philippines
Chinese University of Hong Kong
Nanfang Hospital, Southern Medical University

Recruiting

PPI Infusion Versus Oral Acid Pump Inhibitors for Bleeding Peptic Ulcers

Proton Pump Inhibitors | Upper GI Bleeding

China
Takeda

Completed

Comparison of TAK-438 (Vonoprazan) to Lansoprazole in the Treatment of Gastric Ulcer Participants With or Without Helicobacter Pylori Infection

Gastric Ulcer

Taiwan, China, Korea, Republic of, Philippines
Dow University of Health Sciences

Completed

Vonoprazan in Helicobacter Pylori Treatment an RCT

Helicobacter Pylori Infection

Pakistan
Shandong University
The Affiliated Hospital of Qingdao University; Taian City Central Hospital; Weifang... and other collaborators

Completed

The Study on the Selection of Time for Retreatment of Helicobacter Pylori After Eradication Failure

Helicobacter Pylori

China
Takeda

Completed

Phase 3 Study to Evaluate the Acid-Inhibitory Effect of Multiple Oral Doses of Vonoprazan (TAK-438)

Healthy Volunteers

Japan
First People's Hospital of Hangzhou

Recruiting

A RCT of the Efficacy of Vonoprazan 20mg QD in the Treatment of Helicobacter Pylori Infection (VATH-1)

Helicobacter Pylori Infection | Proton Pump Inhibitor | Vonoprazan

China
Shinshu University

Recruiting

Efficacy of Proton Pump Inhibitors in Gastrointestinal Erosions and/or Ulcers

Gastrointestinal Erosions and/or Ulcers

Japan
CSL Behring
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Active, not recruiting

Treatment of GVHD in Hematopoietic Stem Cell Transplant (HSCT) Recipients Using AAT Plus Corticosteroids (CS) Compared With Corticosteroids Alone (BMT CTN 1705)

Graft Versus Host Disease (GVHD)

United States

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