Search clinical trials for: XEN 63

Total 1011 results

Prism Eye Institute
Allergan

Recruiting

Safety and Efficacy of an Ab Interno Gelatin Stent (XEN63) With or Without Mitomycin C

Glaucoma, Open-Angle

Canada
Valbiotis
Laval University; Centre de Recherche de l'Institut Universitaire de Cardiologie... and other collaborators

Recruiting

Mode of Action (MoA) Study of TOTUM-63 in Individuals at Increased Cardio-metabolic Risk

Prediabetic State | Overweight and Obesity | Dysglycemia

Canada
Valbiotis
Institut Pasteur de Lille; Biofortis Mérieux NutriSciences

Completed

Effect of Totum-63, Active Ingredient of Valedia, on Glucose and Lipid Homeostasis on Subjects With Prediabetes (TOTUM-63 TWO)

Obesity | Disease | Insulin Resistance | Type 2 Diabetes | Hypertriglyceridemia | Prediabetes

France, Ireland, Serbia, Slovenia
Tioga Pharmaceuticals

Completed

A Metabolite Identification, Mass Balance, and PK Study of [14C]-Asimadoline to Healthy Adult Male Volunteers

Healthy

United States
King Saud University

Completed

Muscle Vibration and Joint Position Sense

Vibration; Exposure

Saudi Arabia
Complejo Hospitalario Universitario de Albacete
University of Castilla-La Mancha

Recruiting

"Efficacy of Intermittent Enteral Nutrition Versus Continuous Administration in Intensive Care" (ENINCO)

Enteral Nutrition | Critical Care | Gastric Feeding Tube | Feeding Methods

Spain
Oryx GmbH & Co. KG

Completed

Immune Therapy of HPV-induced Cancers

HPV-induced Cancers

Germany
Tioga Pharmaceuticals
RTI Health Solutions

Completed

Study of Asimadoline to Treat Diarrhea-Predominant Irritable Bowel Syndrome (D-IBS)

Diarrhea Predominant Irritable Bowel Syndrome

United States
Pila Pharma

Completed

A Single-dose Trial to Investigate the Safety and Tolerability of XEN-D0501 in Patients With Diabetes Mellitus Type 2

Diabetes Mellitus, Type 2

Denmark
King Saud University

Completed

Effects of Vibrations on the Biceps Brachii Muscle and Grip Strength

Muscle Strength

Saudi Arabia
AqueSys, Inc.

Completed

Evaluation of the XEN Implant in Moderate Primary Open Angle Glaucoma (POAG) Participants

Primary Open Angle Glaucoma

Spain, Austria, Belgium, Italy, Germany, Poland, Switzerland, United Kingdom, Venezuela
Xention Ltd

Completed

Fed-Fasted, Single and Multiple Ascending Dose Trial of XEN-D0103

Atrial Fibrillation

United Kingdom
Swiss Vision Network

Active, not recruiting

Longitudinal Study on Glaucoma Surgery Using XEN® Gel Stent

Glaucoma | Glaucoma, Open-Angle | Glaucoma, Angle-Closure | Glaucoma, Primary Open Angle
Mingche Biotechnology CO., LTD

Not yet recruiting

Evaluate the Efficacy and Safety of Glaucoma Implant in Primary Open Angle Glaucoma

Glaucoma
Chung Shan Medical University

Completed

Traditional Chinese Medicine Suan Tsao Jen Tang and Tian-Wang-Bu-Xin Dan in Patients With Primary Insomnia.

Insomnia
Xeno Biosciences

Not yet recruiting

A Phase 1b Study to Evaluate the Safety of XEN-101

Obesity
Allergan

Completed

Real-world Evidence Study of XEN in Chinese Patients With Refractory Glaucoma

Refractory Glaucoma

China
Xeno Biosciences

Completed

A Phase 1 Study to Evaluate Safety and Tolerability of Single and Multiple Ascending Doses of XEN-101

Healthy

Hungary
Allergan

Completed

Chart Review of XEN 45 Gel Stent: Long Term Performance and Safety Assessment (XEN LT)

Glaucoma

United States
Xention Ltd
Ario Pharma Ltd

Completed

A Study to Assess the Efficacy of XEN-D0501 in Reducing the Cough Frequency in Patients With COPD

Chronic Obstructive Pulmonary Disease

United Kingdom
Price Vision Group

Terminated

Effect of Xen Implantation on the Aqueous Humor Proteome

Primary Open Angle Glaucoma

United States
Xention Ltd
Ario Pharma Ltd

Completed

A Study to Assess the Efficacy of XEN-D0501 in Reducing the Cough Frequency in Patients With Chronic Idiopathic Cough

Chronic Idiopathic Cough

United Kingdom, Ireland
Johns Hopkins University
New York University

Completed

Retrospective Review of Xen Gel Stent Implantation With Open vs. Closed Conjunctiva Approach

Glaucoma, Open-Angle

United States
Valbiotis
Biofortis Mérieux NutriSciences

Completed

Effect of Totum-63 on Glucose and Lipid Homeostasis in Subjects With Dysglycemia (REVERSE-IT) (REVERSE-IT)

Diabetes type2 | Prediabetic State | Dysglycemia

Italy, France, Germany, Poland, Romania, Bulgaria, Hungary
Institut de l'oeil des Laurentides

Recruiting

A Prospective, Single Surgeon, Randomized Control Study Comparing ab Interno XEN Gel Microstent Implantation vs Closed Conjunctiva ab Externo Implantation Performed at the Slit Lamp for the Treatment of Uncontrolled Glaucoma

The Objective of the Study is to Prospectively Compare the Success Rate of ab Externo and Interno Implantation

Canada
Universiti Sains Malaysia
Morinaga Milk Industry Co., LTD

Completed

Bifidobacterium Infantis M-63 Improves Mental Health in Irritable Bowel Syndrome Developed After a Major Flood Disaster

Irritable Bowel Syndrome | Abdominal Pain | Small Intestinal Bacterial Overgrowth
Tioga Pharmaceuticals
RTI Health Solutions

Terminated

Asimadoline for the Treatment of Post-Operative Ileus

Post-Operative Ileus

United States
Washington University School of Medicine
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

To Define the Role of GLP-1 for Improving Glucose Homeostasis in Humans Following Gastric Bypass Surgery

Roux-en-Y Gastric Bypass | Bariatric Surgery | Vertical Sleeve Gastrectomy | Gastric Banding | Bypass, Gastric

United States
Medical University of Graz

Recruiting

Evaluation of Minimal Invasive Glaucoma Surgery

Glaucoma

Austria
Allergan

Completed

XEN-45 Gel Stent Versus Trabeculectomy in Glaucoma: Gold-Standard Pathway Study (GPS) (XEN GPS)

Glaucoma

United States
AqueSys, Inc.
Allergan

Completed

AqueSys XEN 45 Glaucoma Implant in Refractory Glaucoma

Glaucoma | Glaucoma, Open Angle

United States
Kochi University

Completed

Preoperative Oral Supplementation With Branched-Chain Amino Acids (BCAA) Improves Postoperative Quality of Life (KMS)

Hepatocellular Carcinoma | Chronic Liver Disease

Japan
Bayer

Completed

Study on the Safety of BAY 63-2521, How it is Tolerated and the Way the Body Absorbs, Distributes and Gets Rid of the Study Drug Given as a Single Oral Dose of 1 mg Tablet in Participants With Renal Impairment and Healthy Participants Matched for Age-, Gender-, and Weight

Clinical Pharmacology

Germany
Oryx GmbH & Co. KG

Completed

Cisplatin-based Chemotherapy Combined With P16_37-63 Peptide Vaccination in Patients With HPV-positive Cancers (VICORYX-2)

HPV-induced Cancers

Germany
Pila Pharma
Biomapas

Completed

A Trial Investigating the Effect of 4 Weeks Dosing of XEN-D0501 on Blood Glucose Reduction in Patients With Diabetes

Diabetes Mellitus, Type 2 | Pharmacokinetics | Efficacy | Safety

Lithuania
Danish Headache Center

Not yet recruiting

Effect of Riocigaut on Migraine Attack Induction and Cerebral Vasodilation in Migraine Patients.

Migraine Without Aura

Denmark
Bayer

Completed

Study on the Safety of BAY 63-2521, How it is Tolerated and the Way the Body Absorbs, Distributes and Gets Rid of the Study Drug Given as a Single Oral Dose of 1 mg Tablet in Participants With Impaired Liver Function and Healthy Participants Matched for Age-, Gender-, and Weight

Clinical Pharmacology

Germany
Prism Eye Institute
Allergan

Completed

Ab Interno Gelatin Stent With Mitomycin C Using Targeted Supra-tenon's Placement

Glaucoma

Canada
M.D. Anderson Cancer Center

Recruiting

Elotuzumab for the Treatment of JAK2-Mutated Myelofibrosis

Primary Myelofibrosis | Polycythemia Vera, Post-Polycythemic Myelofibrosis Phase | Myelofibrosis Transformation in Essential Thrombocythemia

United States
International CTEPH Association

Terminated

Riociguat in Patients With Operable CTEPH Prior to Pulmonary Endarterectomy (PEA Bridging Study)

Chronic Thromboembolic Pulmonary Hypertension | CTEPH

Germany, United States, United Kingdom, France
Zhongshan Ophthalmic Center, Sun Yat-sen University
Allergan

Active, not recruiting

XEN45 in the Treatment of Chinese Patients With Primary Open-angle Glaucoma

Glaucoma | Glaucoma, Open-Angle | Surgery

China
C. R. Bard

Completed

Xen Matrix™ AB Surgical Graft in Ventral or Incisional Midline Hernias

Incisional Hernia

United States
Centocor, Inc.

Completed

An Effectiveness and Safety Study of CNTO 1275 in Patients With Active Psoriatic Arthritis

Psoriatic Arthritis

United States, Canada, Switzerland, Finland, Denmark
Claret Medical
Meditrial Europe Ltd.

Completed

Carotid Filtration During Endovascular Aortic Valve Implantation

Heart Diseases
Seno Medical Instruments Inc.

Suspended

Clinical Evaluation of Opto-Acoustic Image Quality With the Gen1B Duplex Probe in Breast Applications

Breast Cancer

United States
University Hospital, Bordeaux
Institut National de la Santé Et de la Recherche Médicale, France

Completed

Relation Between Pregnenolone Endocannabinoids in Normal-weight and Obese Men (CannaPREG)

Obesity

France
Federico II University

Completed

Bifidobacteria In Children With Abdominal Pain-Associated Functional Gastrointestinal Disorders

Irritable Bowel Syndrome | Dyspepsia Chronic

Italy
Abbott Medical Devices

Completed

Protected Carotid Artery Stenting in Subjects at High Risk for Carotid Endarterectomy (CEA) (PROTECT) (PROTECT)

Carotid Artery Disease

United States
Genocea Biosciences, Inc.

Completed

Safety and Immunogenicity Study of Prophylactic Streptococcus Pneumoniae Vaccine

Streptococcus Pneumoniae

United States
Public Health England

Completed

Response of United Kingdom (UK) Infants to a Reduced Primary Schedule With Meningococcal C and Pneumococcal Conjugate Vaccines (sched1)

Pneumococcal Infections | Meningococcal Infections

United Kingdom

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