Search clinical trials for: cfDNA

Total 161 results

University Hospital, Strasbourg, France

Recruiting

Identification of Y Chromosome From Free Circulating DNA in Patients With Turner Syndrome (Turner-Ylc)

Turner Syndrome

France
Second Affiliated Hospital, School of Medicine,...
OmixScience Co., Ltd.

Recruiting

Exploring a Breast Cancer Early Screening Model Based on cfDNA

Breast Cancer | Breast Fibroadenoma | Breast Hypoplasia

China
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Assesment the Efficacy of Dd-cfDNA in Routine Patient Care in Kidney Transplant Recipients" (AI-CARE)

Renal Transplantation

France
Air Force Military Medical University, China

Recruiting

A Single-center, Prospective Cohort Study on the Differentiation of Benign and Malignant Bile Duct Stenosis Based on Bile and Peripheral Blood cfDNA Methylation Profiles

Bile Duct Diseases | Bile Duct Neoplasms | Jaundice, Obstructive

China
Qiu Lugui
Guangzhou Burning Rock Dx Co., Ltd.

Recruiting

Assessment of Early Detection and Prognosis Based on cfDNA Methylation in Multiple Myeloma

Multiple Myeloma

China
University Hospital Tuebingen

Recruiting

First Trimester Screening for Trisomy 21, 18, 13 and 22q11.2 Deletion Syndrome (ReFaPo02)

Pregnancy

Germany
Quest Diagnostics-Nichols Insitute
Illumina, Inc.

Terminated

Cell-free DNA Analysis of Chromosome Anomalies in Early Pregnancy Loss

Early Pregnancy Loss

United States
Cancer Institute and Hospital, Chinese Academy...
Questgenomics

Unknown

Dynamic Monitoring of HER2 and ctDNA Specific Mutations in Patients With Recurrent or Metastatic Breast Cancer by Digital PCR

Recurrent or Metastatic Breast Cancer

China
Hospital Pedro Hispano
Diogo Melo Pinto, MD, Hospital Pedro Hispano; Telma Fonseca, MD, Centro Hospitalar... and other collaborators

Completed

Evaluation of cfDNA as a Marker of Response in Rectal Cancer

Cancer of Rectum

Portugal
Jiayuan Sun

Completed

Methylation of cfDNA in Diagnosing and Monitoring Pulmonary Nodule

Pulmonary Nodule, Solitary

China
Peking University

Unknown

Liquid Biopsy in Monitoring the Therapeutic Efficacy of Targeted Therapy in Advanced/Metastatic Gastric Cancer

Gastric Cancer

China
Fujian Cancer Hospital

Unknown

Next-generation Sequencing in Gastrointestinal Cancer

Gastrointestinal Cancer

China
Universitair Ziekenhuis Brussel

Recruiting

Whole-body DW-MRI and cfDNA Analysis for the Surveillance of Melanoma Patients at High Risk for Recurrence. (DW-MRi)

Melanoma

Belgium
Shanghai Changzheng Hospital

Unknown

Evaluation of Ultrasensitive Chromosomal Aneuploidy Detection for Detecting Minimal Residual Disease in Multiple Myeloma (EUCADD)

Multiple Myeloma

China
Fudan University
Guangzhou Burning Rock Dx Co., Ltd.

Recruiting

Predictive Value of ctDNA for NED Status in mCRC and Its Utility in Guiding Therapeutic Intervention

Metastatic Colorectal Cancer | No Evidence of Disease Status | ctDNA Monitoring

China
University Medical Center Ho Chi Minh City (UMC)

Recruiting

Monitoring Minimal Residual Disease in Gastric Cancer by Liquid Biopsy Study Description

Gastric Cancer | ctDNA

Vietnam
Second Affiliated Hospital of Soochow University

Not yet recruiting

Plasma cfDNA Testing Guiding the Treatment Decisions of DLBCL

Lymphoma, Large B-Cell, Diffuse

China
Cadex Genomics

Completed

Development of a Cell Free DNA Assay as a Biomarker for Predicting Early Non-response to Therapy in Metastatic Cancer

Metastatic Colorectal Cancer | Metastatic Breast Cancer | Metastatic Non-Small Cell Lung Carcinoma

United States, Canada
Vastra Gotaland Region
Karolinska University Hospital; Lund University Hospital

Completed

A New Biomarker for the Non-invasive Diagnosis of Rejection After Heart Transplantation (BIODRAFT)

Heart Transplant Rejection

Sweden
University Hospital, Basel, Switzerland
Research Center for Clinical Neuroimmunology and Neuroscience Basel

Not yet recruiting

Implementation of Liquid Biopsies During Routine Clinical Care in Patients With Advanced Malignancies (LIQPLAT) (LIQPLAT)

Advanced Solid Tumor
The First Hospital of Jilin University
Geneplus-Beijing Co. Ltd.

Recruiting

Exploring the Potential of ctDNA-MRD for Recurrence Surveillance and Prognostic Evaluation in High-risk Endometrial Cancer

Endometrial Cancer

China
Zhejiang University

Not yet recruiting

The Feasibility of Dynamic Liquid Biopsy Monitoring During Neoadjuvant Treatment for EGFR-mutated NSCLC

EGF-R Positive Non-Small Cell Lung Cancer
Azienda Ospedaliera Universitaria Integrata Verona

Recruiting

Circulating Tumor DNA as Surgical Biomarker in Patients With PancrEatic Adenocarcinoma for Statement of Resectability (CASPER)

PDAC - Pancreatic Ductal Adenocarcinoma

Italy
Hospices Civils de Lyon

Recruiting

The circTeloDIAG: Liquid Biopsy for Glioma Tumor (circTeloDIAG)

Glioma

France
University of Maryland, Baltimore
Georgetown University; University of Wisconsin, Madison

Active, not recruiting

Eliminating the Need for Pancreas Biopsy Using Peripheral Blood Cell-free DNA (PancDX)

Transplant;Failure,Kidney | Transplant; Failure, Pancreas | Rejection Acute Renal | Rejection Acute Pancreas

United States
Shanghai Pulmonary Hospital, Shanghai, China

Unknown

Chromosomal Instability as a Surrogate Biomarker of Drug Resistance in Immunotherapy for Lung Cancer Patients (CINSBDRILCP)

Lung Cancer

China
Washington University School of Medicine
University of Texas; CareDx

Recruiting

Allosure in Simultaneous Pancreas Kidney Transplant

Kidney Pancreas Transplant

United States
Royal Marsden NHS Foundation Trust
Massachusetts General Hospital; Natera, Inc.

Recruiting

Safe De-escalation of Chemotherapy for Stage 1 Breast Cancer (Safe-De)

Breast Cancer

United Kingdom
Massachusetts General Hospital
C2i Genomics; Spier Family Foundation

Not yet recruiting

ctDNA and Organ Preservation/Pathologic CR in Rectal Cancer

Rectal Cancer | Non Metastatic Rectal Cancer

United States
GeneCast Biotechnology Co., Ltd.
The First Affiliated Hospital of Air Force Military Medical University (Xijing...

Recruiting

Gastric Cancer Early Detection by Multi-dimensional Analysis of cfDNA

Gastric Cancer

China
Universal Diagnostics

Recruiting

Collection of Samples USOPTIVAL Study

Colorectal Cancer (CRC) | Advanced Adenomas (AA)

United States
University Hospital, Limoges

Completed

Diagnostic and Prognosis Value of Circulating DNA for CRC Patients' Surveillance After Curative Treatment (ADNCirc)

Colorectal Cancer

France
Sun Yat-sen University

Unknown

ctDNA for Prediction of Relapse in Gastric Cancer

Stomach Neoplasms

China
First People's Hospital of Hangzhou

Unknown

ALK/ROS1/MET Mutations on Plasma ctDNA in Patients With NSCLC

Non-small Cell Lung Cancer Stage III | Adenocarcinoma of Lung | Non-Small-Cell Lung Cancer Metastatic | EGFR Wildtype

China
Swiss Group for Clinical Cancer Research

Recruiting

LIBERTY: Liquid Biopsy to Diagnose and Monitor CNS Involvement in High-risk B Cell Non-Hodgkin Lymphoma (SAKK 38/23)

Non-hodgkin Lymphoma, B Cell

Switzerland
Shanghai Zhongshan Hospital
Fudan University; Amoy Diagnostics Co., LTD

Not yet recruiting

Application of ctDNA in Evaluation of Neoadjuvant Chemotherapy Efficacy and Exploration of Chemoresistance Mechanisms in Pancreatic Cancer

Patients With Non-metastatic Pancreatic Cancer | Evaluation of Tumor Resectability Shall be Made in Consensus at Multidisciplinary Meetings, According to NCCN Guideline Version 1.2022 Pancreatic Adenocarcinoma

China
Gynaecologisch Oncologisch Centrum Zuid
Catharina Ziekenhuis Eindhoven; Amsterdam UMC, location VUmc; The Netherlands... and other collaborators

Recruiting

Ovarium Cancer Detection by TEP's and ctDNA

Ovarian Neoplasms

Netherlands
Centre Hospitalier Departemental Vendee

Completed

Early Assessment of Response to Treatment of Metastatic LUng Tumors Based on CIrculating Tumor DNA (ELUCID)

Metastatic Non-small Cell Lung Cancer

France
Hunan Cancer Hospital

Completed

Clinical Application of Circulating Tumor DNA (ctDNA) in Patients With Late-stage Breast Cancer (ACTDNA)

Metastatic Breast Cancer | Circulating Tumor DNA | Gene Abnormality
Sixth Affiliated Hospital, Sun Yat-sen University

Unknown

The Implication of ctDNA in the Recurrence Surveillance of Stage II and III Colorectal Cancer

Colorectal Cancer | Surveillance | ctDNA

China
Sun Yat-sen University
First Affiliated Hospital, Sun Yat-Sen University

Unknown

ctDNA Dynamic Monitoring and Its Role of Prognosis in Stage I NSCLS by NGS

Non-small Cell Lung Cancer Stage I

China
National Cancer Center, Japan

Recruiting

Asian Multicenter Prospective Study of ctDNA Sequencing (A-TRAIN)

Cervical Cancer | Nasopharyngeal Carcinoma | Ovarian Cancer | Triple Negative Breast Cancer | Endometrial Cancer | Ovarian Clear Cell Carcinoma

Japan, Korea, Republic of, Malaysia, Thailand, Philippines, Singapore, Taiwan, Vietnam
Sun Yat-sen University
Hangzhou Repugene Technology Co., Ltd.

Recruiting

Evaluation ctDNA in Patients of Non-Small-Cell Lung Cancer Following Resection (EVOLUTION)

Non-Small Cell Lung Cancer

China
Inova Health Care Services
Natera, Inc.

Withdrawn

Observational Study of ctDNA in Resectable and Borderline Resectable Pancreatic Cancer

Pancreatic Cancer

United States
Samsung Medical Center

Active, not recruiting

Exosome as the Prognostic and Predictive Biomarker in EBC Patients

Triple Negative Breast Cancer | HER2-positive Breast Cancer

Korea, Republic of
Cancer Institute and Hospital, Chinese Academy...
Cangzhou Central Hospital; Weifang Medical University; Heji Hospital affiliated... and other collaborators

Recruiting

Early Screening of Colorectal Cancer Based on Plasma Multi-omics Combining With Artificial Intelligence (RECOMMEND)

Colorectal Cancer | Colorectal Adenoma

China
Universitaire Ziekenhuizen KU Leuven

Recruiting

Predictive Value of Neurovascular Coupling in Infants With COngenital Heart Disease (NICO)

Neurodevelopmental Disorders | Biomarkers | Congenital Heart Disease | Electroencephalography | Near-Infrared Spectroscopy

Belgium
University of California, Irvine

Recruiting

Pilot Comparing ctDNA IDV vs. SPV Sample in Pts Undergoing Biopsies for Hepatobiliary and Pancreatic Cancers

Hepatocellular Carcinoma | Pancreatic Cancer | Cholangiocarcinoma | Pancreatic Carcinoma | Hepatobiliary Cancer | Ampullary Cancer

United States
Fudan University

Recruiting

Evaluation of Circulating Tumor DNA Guided Surveillance Strategy of Stage III Colorectal Cancer: an Open, Prospective, Randomized Controlled Cohort Study

Circulating Tumor DNA | Stage III Colorectal Cancer

China
Sixth Affiliated Hospital, Sun Yat-sen University

Recruiting

ctDNA as a Assisted Diagnosis, Early Intervention and Prognostic Marker for Peritoneal Metastases From Colorectal Cancer

Colorectal Cancer | Peritoneal Metastases

China

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