Search clinical trials for: cyclosporine A (CyA)

Total 14353 results

Guangxi Medical University

Unknown

the Effects and Safety of Idarubicin-strengthened Pretreatment Program and Conventional Busulfan Cyclophosphamide Pretreatment Program on High-risk Acute Myeloid Leukemia Patient (IDBUCY)

Acute Myeloid Leukemia

China
Northwestern University
Northwestern Memorial Hospital

Completed

Immune Tolerance and Alloreactivity in Liver Transplant Recipients on Different Monotherapy Immunosuppressive Agents

Immunosuppression | Liver Transplant Rejection

United States
University of Maryland, Baltimore

Completed

Aerosol Liposomal Cyclosporine for Chronic Rejection in Lung Transplant Recipients

Bronchiolitis Obliterans | Chronic Rejection of Lung Transplant | Disorder Related to Lung Transplantation | Decreased Immunologic Activity

United States
Taejoon Pharmaceutical Co., Ltd.

Completed

Efficacy and Safety Study of TJCS for Treatment of Moderate to Severe Dry Eye Syndromes

Dry Eye Syndromes

Korea, Republic of
Taejoon Pharmaceutical Co., Ltd.

Completed

Evaluating HA 0.15% Compared With Cyclosporine 0.05%, and Efficacy of Combination Therapy in Dry Eye Disease Patients

Dry Eye | Dry Eye Syndromes

Korea, Republic of
Novartis

Completed

Efficacy and Safety of Basiliximab, Cyclosporine/Cyclosporine Microemulsion, and Steroids in Pediatric de Novo Liver Transplant Recipients Avoiding Intraoperative Steroids

Liver Transplantation | Infection

Germany
East Carolina University
Astellas Pharma US, Inc.

Completed

Optima: Optimizing Prograf Therapy in Maintenance Allografts II (OPTIMAII)

Kidney Transplantation

United States
Chinese PLA General Hospital
Huazhong University of Science and Technology; LinkDoc Technology (Beijing)...

Recruiting

Effect of Huaier Granule on the Treatment of Idiopathic Membranous Nephropathy

Nephropathy | Idiopathic Membranous Nephropathy | Glomerular Diseases

China
Novartis Pharmaceuticals

Completed

Study Investigating a Standard Regimen in de Novo Kidney Transplant Patients Versus a Calcineurin Inhibitor (CNI)-Free Regimen and a CNI-low Dose Regimen

Kidney Transplantation

Germany, Switzerland
University Hospital, Ghent
Novartis; Funds for Research in Ophthalmology (FRO) of Belgium

Completed

Topical Cyclosporine for Vernal Keratoconjunctivitis (VKC) in Rwanda

Vernal Keratoconjunctivitis

Rwanda
Yonsei University

Recruiting

A Clinical Trial to Evaluate the Clinical Efficacy of Cyclosporine 0.1% (Ikervis®) for Moderate to Severe Dry Eye Patients. (IKE-03-SWITCHING)

Moderate to Severe Dry Eye

Korea, Republic of
Toyos Clinic
Sun Pharmaceutical Industries Limited

Recruiting

Clinical Efficacy of Two Topical Dry Eye Drops for Central Corneal Stain Clearing Over 90 Days

Dry Eye

United States
National Institute of Diabetes and Digestive and...

Recruiting

Rituximab Plus Cyclosporine in Idiopathic Membranous Nephropathy

Proteinuria | Nephrotic Syndrome | Autoimmune Disease | Glomerular Disease | Membranous Glomerulonephritis

United States
Postgraduate Institute of Medical Education and...

Completed

To Assess and Compare the Efficacy of Cyclosporine Versus Azathioprine in the Treatment of Chronic Refractory Urticaria

Chronic Refractory Urticaria

India
Chulalongkorn University

Unknown

Study of Cyclosporine Withdrawal Regimen in Thai Renal Transplant Recipients

Renal Transplant

Thailand
The University of Texas Health Science Center,...

Terminated

Trial of Cyclosporine for Myocardial Protection During Open Heart Surgery (CYCLO1)

Cardiac Surgical Procedures

United States
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating Sirolimus and Cyclosporine in Kidney Transplant Recipients

Renal Transplantation
Taejoon Pharmaceutical Co., Ltd.

Recruiting

Evaluating the Efficacy and Safety of TJO-087 in Moderate to Severe Dry Eye Disease Patients

Dry Eye Syndrome

Korea, Republic of
University of North Carolina, Chapel Hill
Allergan

Completed

Topical Cyclosporine Suspension for the Treatment of Brittle Nails

Brittle Nail Syndrome

United States
Tibotec Pharmaceuticals, Ireland

Completed

A Study in Healthy Participants Investigating the Effect of TMC435 on the Pharmacokinetics of Immunosuppressants Cyclosporine and Tacrolimus

Hepatitis C Virus

Belgium
Fred Hutchinson Cancer Center

Completed

Treosulfan, Fludarabine Phosphate, and Total-Body Irradiation in Treating Patients With Hematological Cancer Who Are Undergoing Umbilical Cord Blood Transplant

Myelodysplastic Syndrome (MDS) | Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive | Chronic Myelogenous Leukemia, BCR-ABL1 Positive | Acute Biphenotypic Leukemia | Acute Myeloid Leukemia in Remission | Acute Lymphoblastic Leukemia in Remission | Blasts Under 5 Percent of Bone Marrow...

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Fludarabine Phosphate and Total-Body Irradiation Before Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Chronic Lymphocytic Leukemia or Small Lymphocytic Leukemia

Chronic Lymphocytic Leukemia | Recurrent Small Lymphocytic Lymphoma | Prolymphocytic Leukemia | Refractory Chronic Lymphocytic Leukemia | Recurrent Chronic Lymphocytic Leukemia | T-Cell Prolymphocytic Leukemia | B-Cell Prolymphocytic Leukemia

United States, Italy
Enzyvant Therapeutics GmBH

Approved for marketing

Expanded Access Protocol Thymus Transplantation

Immunodeficiency | Poor Thymic Function | Athymia | Immunoreconstitution | Thymus Transplantation | Low T Cell Numbers
Turkish Society of Hematology

Unknown

Turkish Acquired Haemophilia Registry (EHEM)

Acquired Haemophilia

Turkey
St. Jude Children's Research Hospital

Completed

Treatment of Severe Osteogenesis Imperfecta by Allogeneic Bone Marrow Transplantation

Osteogenesis Imperfecta

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Radiolabeled Monoclonal Antibody Therapy, Fludarabine Phosphate, and Low-Dose Total-Body Irradiation Followed by Donor Stem Cell Transplant and Immunosuppression Therapy in Treating Older Patients With Advanced Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndromes

Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities | Adult Acute Myeloid Leukemia With Del(5q) | Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) | Adult Acute Myeloid Leukemia With t(16;16)(p13;q22) | Adult... and other conditions

United States
Boston Children's Hospital

Terminated

A Study to Compare Treatment With Sirolimus Versus Standard Treatment in Patients Who Have Received a Kidney Transplant

Kidney Transplantation | End-Stage Renal Disease

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Terminated

Iodine I 131 Monoclonal Antibody BC8, Fludarabine Phosphate, Total Body Irradiation, and Donor Stem Cell Transplant Followed by Cyclosporine and Mycophenolate Mofetil in Treating Patients With Advanced Acute Myeloid Leukemia or Myelodysplastic Syndrome

Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities | Adult Acute Myeloid Leukemia With Del(5q) | Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) | Adult Acute Myeloid Leukemia With t(16;16)(p13;q22) | Adult... and other conditions

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Alemtuzumab, Fludarabine Phosphate, and Total-Body Irradiation Followed by Cyclosporine and Mycophenolate Mofetil in Treating Patients Who Are Undergoing Donor Stem Cell Transplant for Hematologic Cancer

Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Juvenile Myelomonocytic Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell... and other conditions

United States, Italy
Montefiore Medical Center
Nationwide Children's Hospital; Children's Hospital Los Angeles

Terminated

A Multi-Institutional Pilot Study of Allogeneic Hematopoietic Stem Cell Transplantation for Patients With Malignant Neuro-Epithelial and Other Solid Tumors

Solid Tumor | Allogeneic Hematopoietic Stem Cell Transplantation | Neuroepithelial Tumor

United States
Center for Ophthalmic and Vision Research, LLC
Sun Pharmaceutical Industries Limited

Completed

CEQUA for Sjogren's Syndrome Dry Eye

Dry Eye | Dry Eye Syndromes | Sjogren's Syndrome

United States
Hanlim Pharm. Co., Ltd.

Completed

Study of Cyclosporine Ophthalmic Soution Group and Cyclosporine Ophthalmic Suspension Group (Cyclosporine)

Dry Eye Syndromes

Korea, Republic of
Julian M. Mackay-Wiggan
Allergan

Completed

Restasis for Treatment of Brittle Nails

Brittle Nails

United States
Heidelberg University
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Rapamycin Use in Calcineurin Inhibitor (CNI)-Free Immunosuppression for Stabilization/Improvement of Renal Function After Heart Transplantation

Renal Failure | Heart Transplantation

Germany
Baxalta now part of Shire

Terminated

Prevention of Graft-Versus-Host Disease in Patients With Advanced Leukemia or Lymphoma Who Are Eligible for Peripheral Stem Cell Transplantation

Lymphoma | Leukemia | Graft Versus Host Disease

United States, Australia
Hanlim Pharm. Co., Ltd.

Completed

Study of Tisporin Eye Drops Group and Restasis Eye Drops Group After Treatment, Each Treatment Group Comparisons for Evaluation of Efficacy and Safety in Moderate to Severe Dry Eye Disease (HL_TSPR_302)

Dry Eye Syndromes

Korea, Republic of
National Taiwan University Hospital

Unknown

The Pharmacokinetics of Sirolimus When Combined With Cyclosporine or Tacrolimus in Renal Transplant Patients

Kidney Transplantation | Immunosuppression | Transplantation

Taiwan
Novartis Pharmaceuticals

Completed

12 Month Athena Study: Everolimus vs. Standard Regimen in de Novo Kidney Transplant Patients (ATHENA)

Kidney Transplantation | Renal Transplantation

Germany, France
Novartis Pharmaceuticals

Completed

Efficacy and Safety of Everolimus in Combination With Cyclosporine Microemulsion Versus Everolimus in Combination With Enteric-coated Mycophenolate Sodium (EC-MPS), in Adult Renal Transplant Patients in Maintenance.

Renal Transplantation

France
Hospital Authority, Hong Kong
Hoffmann-La Roche

Unknown

Mycophenolate Mofetil for the Prophylaxis of Graft-versus-host Disease in High Risk Allogeneic Stem Cell Transplantation

Hematopoietic Stem Cell Transplantation | Graft vs Host Disease

China
Milton S. Hershey Medical Center
Novartis Pharmaceuticals

Completed

Conversion to Everolimus From Calcineurin Inhibitor With Mycophenolic Acid: Impact on Long Term Renal Function in Liver Transplantation.

Renal Failure | Immunosuppression

United States
Bristol-Myers Squibb

Recruiting

A Study to Evaluate the Benefits and Risks of Conversion of Existing Adolescent Kidney Transplant Recipients Aged 12 to <18 Years to a Belatacept-based Immunosuppressive Regimen as Compared to Continuation of a Calcineurin Inhibitor-based Regimen, and Their Adherence to Immunosuppressive Medications

Renal Allograft Recipients

France, United States, Germany, Spain, United Kingdom, Italy, Netherlands, Belgium
Boston Children's Hospital
Massachusetts General Hospital; Mayo Clinic; Karolinska University Hospital; Baylor... and other collaborators

Active, not recruiting

Radiation- and Alkylator-free Bone Marrow Transplantation Regimen for Patients With Dyskeratosis Congenita

Aplastic Anemia | Dyskeratosis Congenita | Hoyeraal Hreidarsson Syndrome | Revesz Syndrome

United States, Norway, Sweden
Campus Bio-Medico University
University of Padova; University of Genova

Completed

Cyclosporin A Eye Drop Treatment in Vernal Keratoconjunctivitis

Vernal Keratoconjunctivitis

Italy
Karolinska Institutet

Recruiting

The Effectiveness of A-CRA in Compulsory Institutional Care for Youth (A-CRA at SiS)

Substance Use Disorders | Criminal Behavior

Sweden
Medical College of Wisconsin
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Completed

Single vs Double Umbilical Cord Blood Transplants in Children With High Risk Leukemia and Myelodysplasia (BMT CTN 0501)

Myelodysplastic Syndrome | Acute Lymphocytic Leukemia | Acute Myelogenous Leukemia | Chronic Myelogenous Leukemia | Natural Killer Cell Lymphoblastic Leukemia/Lymphoma

United States, Australia, Canada
Masonic Cancer Center, University of Minnesota

Completed

HSCT for High Risk Inherited Inborn Errors

Wolman Disease | Adrenoleukodystrophy | Metachromatic Leukodystrophy | Sanfilippo Syndrome | GM1 Gangliosidosis | Globoid Cell Leukodystrophy | Tay Sachs Disease | Sandhoffs Disease | I-Cell Disease

United States
Masonic Cancer Center, University of Minnesota

Completed

Allogeneic Bone Marrow Transplant for Inherited Metabolic Disorders

Mucopolysaccharidosis | Hurler Syndrome | Sphingolipidoses | Peroxisomal Disorders | Krabbe Disease | Adrenoleukodystrophy (ALD) | Hunter Syndrome | Sly Syndrome | Fucosidosis | Aspartylglucosaminuria | Alpha Mannosidosis | Metachromatic Leukodystrophy (MLD) | Maroteaux-Lamy Syndrome

United States
Hospices Civils de Lyon

Completed

Study of Methotrexate Efficacy Versus Cyclosporine in Moderate to Severe Atopic Dermatitis Patients (METHODA)

Atopic Dermatitis

France
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Suspended

211^At-BC8-B10 Before Donor Stem Cell Transplant in Treating Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Myelodysplastic Syndrome, or Mixed-Phenotype Acute Leukemia

Acute Myeloid Leukemia | Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome | Chronic Myelomonocytic Leukemia | Acute Lymphoblastic Leukemia | Recurrent Acute Myeloid Leukemia | Refractory Acute Myeloid Leukemia | Myelodysplastic Syndrome With Excess Blasts | Recurrent Acute Lymphoblastic... and other conditions

United States

Search clinical trials for: cyclosporine A (CyA)

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