Search clinical trials for: nasal naloxone

Total 2721 results

Pocket Naloxone Corp

Completed

Pharmacokinetic Evaluation of a New Naloxone Nasal Swab, Naloxone Nasal Spray, and Intramuscular Naloxone Injection in Healthy Volunteers

Opioid Overdose

Canada
State University of New York - Upstate Medical...
Binghamton University

Completed

A Usability Assessment of Naloxone Administration by Untrained Community Members

Harm Reduction | Opioid-use Disorder | Naloxone

United States
Food and Drug Administration (FDA)
Spaulding Clinical Research LLC

Completed

Clinical Study to Investigate the Pharmacokinetics of Multiple Repeated Doses of Intranasal Naloxone

Healthy Subjects | Pharmacokinetics | Opioid Antagonist

United States
INSYS Therapeutics Inc

Completed

A Study to Compare Bioavailability of Naloxone Nasal Spray and Naloxone Hydrochloride (HCl) Intramuscular Injection (IM) in Healthy Volunteers

Healthy Volunteer

United States
INSYS Therapeutics Inc

Completed

A Study to Compare Bioavailability of Naloxone Nasal Spray, Naloxone Hydrochloride (HCl) Intravenous (IV) and Intramuscular Injection (IM) in Healthy Volunteers

Healthy Volunteer

United States
Finnish Institute for Health and Welfare

Unknown

Effects of Intranasal Naloxone on Gambling Urges and Craving in Gambling Disorder (NalGamb)

Naloxone | Gambling Disorder | Opioid Antagonist | Pathological Gambling

Finland
Leiden University Medical Center
U.S. Food and Drug Administration (FDA)

Recruiting

Reversal of Opioid-induced Respiratory Depression With Opioid Antagonists (ROAR)

Chronic Opioid Use | Opioid Induced Respiratory Depression

Netherlands
University of Minnesota

Terminated

Intra-nasal Naloxone for Treatment of Impaired Awareness of Hypoglycemia

Type 1 Diabetes | Hypoglycemia Unawareness

United States
Emergent BioSolutions

Completed

Pharmacokinetics (PK) and Safety of Multiple Doses of Intranasal Naloxone in Healthy Adults

Opioid Overdose

United States
Norwegian University of Science and Technology
St. Olavs Hospital

Completed

Bioavailability of a New Formulation of Nasal Naloxone for Prehospital Use

Drug Overdose

Norway
Johns Hopkins University
Cure Addiction Now

Recruiting

Behavioral Pharmacological Examination of a Novel Buprenorphine Induction Method Among Individuals Who Use Fentanyl (NBIM)

Opioid Use Disorder

United States
Region Skane

Active, not recruiting

Naloxone Treatment in Skåne County - Effect on Drug-related Mortality and Overdose-related Complications

Opioid Abuse

Sweden
Samjin Pharmaceutical Co., Ltd.

Completed

A Phase 4 Clinical Study to Investigate the Efficacy and Safety of Naloxone HCI IV in Patients With Stroke

Stroke, Acute

Korea, Republic of
Nasus Pharma

Completed

A Single-Dose, Bioequivalence Study of FMXIN001 4 mg Microspheres Powder

Opioid Overdose

Canada
University of Cincinnati
National Institute on Drug Abuse (NIDA)

Completed

A Tailored, Peer-delivered Intervention to Reduce Recurring Opioid Overdoses (TTIP-PRO)

Opioid-Related Disorders | Substance Abuse | Drug Overdose | Drug Abuse | Drug Addiction

United States
Judith Feinberg

Unknown

Nasal Naloxone for Narcotic Overdose

Drug Overdose

United States
Albert Einstein College of Medicine
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National...

Active, not recruiting

Novel Approach for the Prevention of Hypoglycemia Associated Autonomic Failure (HAAF)

Hypoglycemia | Diabetes Mellitus, Type 1 | Hypoglycemia Unawareness

United States
mads u werner
University of Kentucky

Completed

Effect of High-dose Target-controlled Naloxone Infusion on Pain and Hyperalgesia During a Burn Injury (TCI-NX-BI)

Healthy Subjects

Denmark
S.L.A. Pharma AG

Completed

Naloxone SR Capsules in Patients With Opioid Induced Constipation

Chronic Pain | Opioid Induced Constipation

Germany, United Kingdom
mads u werner
University of Kentucky

Completed

Effect of High-dose Naloxone Following Third Molar Extraction (TME)

Pain, Acute | Healthy Subjects | Hyperalgesia | Sensitization, Central | Inflammations, Endodontic

Denmark
Norwegian University of Science and Technology
St. Olavs Hospital; Smerud Medical Research International AS; A/S Den norske...

Completed

Bioavailability of Nasal Naloxone and Injected Naloxone Compared (OPI-15-002)

Drug Overdose

Norway
Norwegian University of Science and Technology
St. Olavs Hospital

Completed

Pharmacokinetics and Pharmacodynamics of a New Formulation of Nasal Naloxone for Prehospital Use (OPI-14-001)

Drug Overdose

Norway
Norwegian University of Science and Technology
St. Olavs Hospital; University of Iceland

Completed

A Pilot Study of the Bioavailability of Nasal Naloxone

Drug Overdose

Norway
University of Washington

Unknown

Subjective Analgesic Effects of Naloxone and Virtual Reality (Narcan)

Pain

United States
Duke University
National Institute on Drug Abuse (NIDA); The Emmes Company, LLC

Completed

Buprenorphine Physician-Pharmacist Collaboration in the Management of Patients With Opioid Use Disorder: CTN 0075 (Pharm-OUD-Care)

Opioid Use Disorder

United States
Johns Hopkins Bloomberg School of Public Health
Centers for Disease Control and Prevention

Completed

An Evaluation of a Social Network Intervention for Primary and Secondary Prevention of Opioid Overdoses

Overdose

United States
Parc de Salut Mar
Food and Drug Administration (FDA)

Recruiting

Pharmacokinetics of Intravenous and Intranasal Formulations of Naloxone in Healthy Volunteers.

Healthy

Spain
University of Minnesota

Completed

Naloxone, Hypoglycemia and Exercise

Diabetes Mellitus, Type 1

United States
Finnish Institute for Health and Welfare

Completed

Treatment of Gambling Disorder With Fast Acting Opiate Antagonist, Naloxone Nasal Spray (NALPILO)

Naloxone | Gambling | Spray | Opioid

Finland
Kaiser Permanente
National Institute on Drug Abuse (NIDA); Denver Health and Hospital Authority

Completed

Impact of Direct Outreach to Expand Access to Naloxone in the Context of Standing Orders

Risk Behavior | Opioid Abuse | Overdose

United States
Norwegian University of Science and Technology
Oslo University Hospital; St. Olavs Hospital

Completed

Naloxone Nasal Spray Compared With Naloxone Injection for Opioid Overdoses Outside the Hospital (NINA-1)

Overdose | Drug Abuse

Norway
Yale University
National Institute on Drug Abuse (NIDA)

Completed

Buprenorphine Maintenance vs. Detoxification in Prescription Opioid Dependence

Opiate Dependence

United States
INSYS Therapeutics Inc

Completed

Study of Buprenorphine-Naloxone Sublingual Spray and Suboxone® Sublingual Film in Healthy Volunteers

Opiate Dependence

United States
Bicycle Health

Enrolling by invitation

Novel Induction to Buprenorphine/Naloxone

Opioid Use Disorder | Opioid Dependence | Opioid Use | Opioid Abuse | Opioid Misuse

United States
National Institute on Drug Abuse (NIDA)
Johns Hopkins University

Terminated

Abuse Potential of Buprenorphine/Naloxone

Opioid-Related Disorders

United States
National Institute on Drug Abuse (NIDA)

Completed

Buprenorphine Combination Tablet Feasibility - 1

Opioid-Related Disorders

United States
National Institute on Drug Abuse (NIDA)
New York MDRU

Completed

Buprenorphine and Naloxone for the Treatment of Opiate Dependence - 1

Substance-Related Disorders | Heroin Dependence

United States
National Institute on Drug Abuse (NIDA)

Completed

Buprenorphine/Naloxone for Treatment of Opiate Dependence - 9

Opioid-Related Disorders

United States
University of Pennsylvania

Completed

Buprenorphine/Naloxone - Facilitated Rehabilitation for Opioid Dependent Adolescents - 1

Opioid-Related Disorders

United States
Dartmouth-Hitchcock Medical Center

Completed

Role of Endorphins in the Perception of Dyspnea in Patients With Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease

United States
Massachusetts General Hospital

Not yet recruiting

Buprenorphine/Naloxone Micro-Dosing for Postoperative Pain Management in Opioid-Tolerant Patients

Post-operative Pain

United States
University of Pennsylvania
Public Health Management Corporation; Philadelphia Department of Public Health and other collaborators

Completed

Rapid Initiation of Drug Treatment Engagement (RIDE)

Overdose | Opioid-use Disorder

United States
National Institute on Drug Abuse (NIDA)
University of Pennsylvania

Completed

Trial of Buprenorphine/Naloxone for Opiate Dependence - 2

Substance-Related Disorders | Opioid-Related Disorders

United States
National Institute on Drug Abuse (NIDA)
New York MDRU

Completed

Buprenorphine/Naloxone in the Treatment of Heroin Dependence - 14

Substance-Related Disorders | Opioid Dependence

United States
National Institute on Drug Abuse (NIDA)
University of Vermont

Completed

Buprenorphine Pharmacology Related to Addiction Treatment - 18

Opioid-Related Disorders

United States
Maimonides Medical Center

Terminated

Buprenorphine Treatment: A Safe Alternative for Opioid Dependent Pain Patients

Opioid Use Disorder

United States
National Institute of Allergy and Infectious Diseases...

Terminated

Assessing Abuse Potential of Parenteral Buprenorphine/Naloxone in Non-Dependent Opioid Abusers

Opioid-Related Disorders

United States
Wayne State University

Completed

Effects of Buprenorphine/Naloxone Dose on Experimental Stress Reactivity and Opioid Abstinence (BOS)

Heroin Dependence | Opioid Use Disorder

United States
National Institute on Drug Abuse (NIDA)
Cincinnati MDRU

Completed

Buprenorphine/Naloxone for Opiate-Dependence Treatment - 1

Substance-Related Disorders | Opioid-Related Disorders

United States
National Institute on Drug Abuse (NIDA)

Completed

Blockade Efficacy of Buprenorphine/Naloxone For Opioid Dependence

Opioid-Related Disorders

United States

Search clinical trials for: nasal naloxone

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