Search clinical trials for: Opioids

Total 4422 results

Kevin J Flynn MD

Withdrawn

Pre-induction Analgesia: Multimodel Regimen vs Aceteminophen for Post Ureteroscopy Pain (MMPITR)

Pain, Postoperative | Kidney Calculi
TriHealth Inc.

Completed

Bupivacaine Liposome Suspension Versus a Concentrated Multi Drug Periarticular Injection

Total Knee Arthroplasty
Reckitt Benckiser LLC
Premier Research Group plc; Aptuit Inc.

Completed

Ibuprofen/Acetaminophen Versus Nurofen Plus® and Panadeine® Extra Dental Pain Study

Post-operative Pain

United States
Janssen Scientific Affairs, LLC
Bausch Health Americas, Inc.; Cipher Pharmaceuticals Inc.

Completed

Study to Evaluate the Effects of Tramadol Hydrochloride on Cardiac Repolarization in Healthy Participants

Healthy

United States
University of Parma

Unknown

OFA - Opioid Free Anesthesia (OFA)

Postoperative Pain

Italy
Nexgen Pharma, Inc
Pharmaceutical Research Unit, Jordan

Completed

Codeine Phosphate/Guaifenesin ER Tablet 30 mg/600 mg Steady State Clinical Study (COGUSS)

Cough

Jordan
Merck Sharp & Dohme LLC

Completed

Effect of Rofecoxib and a Narcotic Analgesic to Treat Pain Following Arthroscopic Surgery (0966-179)(COMPLETED)

Pain, Postoperative Arthroscopy
AcelRx Pharmaceuticals, Inc.

Completed

Effect of Ketoconazole on Sufentanil NanoTab Pharmacokinetics

Pharmacokinetics

United States
Mallinckrodt

Completed

Fed Study of Chlorpheniramine Polistirex and Hydrocodone Polistirex Capsules and Tussionex® Pennkinetic® Extended Release Oral Suspension

Healthy

United States
West China Hospital

Unknown

Midazolam Used Alone or Sequential Use of Midazolam and Propofol/Dexmedetomidine in Mechanically Ventilated Patients

Delirium | Complication | Mechanical Ventilation

China
Kanuni Sultan Suleyman Training and Research Hospital

Completed

A Comparison of the Sedation During Endoscopy in Children

Failed Moderate Sedation During Procedure
Ullevaal University Hospital
University of Oslo

Completed

Analgesic Effect of Paracetamol, Paracetamol + Codeine, Ibuprofen and Their Combination

Pain, Postoperative

Norway
Seoul National University Hospital

Completed

Safety and Efficacy of Fentanyl Citrate in Children

Children

Korea, Republic of
Fudan University

Unknown

Analgesia Effects of Nalbuphine vs Sulfentanil

C.Delivery; Surgery (Previous), Gynecological
Futian People's Hospital
Science and Technology Innovation Commission of Shenzhen Municipality

Unknown

Interventional Bronchoscopy Under Noninvasive Ventilation

Central Airway Stenosis | Noninvasive Positive Pressure Ventilation; | Sedation; | Bronchoscopy； | Interventional；

China
Heinrich-Heine University, Duesseldorf
University Hospital, Essen

Unknown

Effects of Remote Ischemic PreConditioning in Off-pump Versus On-pump Coronary Artery Bypass Grafting(RIPCON) (RIPCON)

Myocardial Injury

Germany
University of Southern Denmark
Odense University Hospital

Terminated

Development of Cocktail for Measuring the Activity of Important Cytochrome P450 Enzymes

Cytochrome P450 Phenotype and Genotype Metrics

Denmark
Nanjing Medical University

Completed

Comparison of Analgesic Efficacy of Fentanyl, Sufentanil and Butorphanol After Remifentanil Anesthesia (CARAN)

Postoperative Pain

China
AstraZeneca
Parexel

Recruiting

Drug-Drug Interaction and Safety of AZD4041 Study (Part 1) and Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of AZD4041 Study in Opioid Use Disorder (Part 2).

Opioid Use Disorder

United States
Wayne State University

Recruiting

Serratus Anterior Plane Block With and Without Adjuvants in Video-assisted Thoracoscopy

Post Operative Pain, Acute

United States
Wayne State University

Recruiting

Are Superficial Parasternal Intercostal Plane (SPIP) Blocks With Bupivacaine and With or Without Adjuvants Helpful for Post-operative Pain After Coronary Artery Bypass Grafting?

Post-operative Pain Management

United States
Kanecia Obie Zimmerman
The Emmes Company, LLC

Recruiting

Anesthetics and Analgesics in Children (ANA01)

Pain | Anesthesia

United States, Canada
Emory University

Recruiting

Paravertebral Nerve Blocks in Neonates

Congenital Heart Disease

United States
Second People's Hospital of Hefei City
Tongji Hospital

Completed

Esketamine and Butorphanol for Post-Lobectomy Pain

Pain | Thoracic Diseases | Esketamine | Post-thoracotomy Pain Syndrome

China
Sixth Affiliated Hospital, Sun Yat-sen University

Completed

Dexmedetomidine Versus Propofol for Sedation During Awake Endotracheal Intubation

Intubation | Sedation

China
University of Arkansas
National Institute on Drug Abuse (NIDA)

Completed

Improving Treatment Outcomes for Prescription Opioid Dependence (GBN)

Drug Dependence

United States
Yantai Yuhuangding Hospital

Completed

Application of Iced Normal Saline Combined With Cocktail Perfusion in Total Knee Arthroplasty

Pain, Postoperative | Blood Loss, Postoperative

China
Centre Hospitalier Universitaire Vaudois
AstraZeneca

Completed

Platelet Inhibition After Pre-hospital Ticagrelor Using Fentanyl Compared to Morphine in Patients With ST-segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention (PERSEUS)

Acute Myocardial Infarction

Switzerland
University of Zurich

Completed

How to Treat Opiate Withdrawal in Neonates

Neonatal Abstinence Syndrome
Tufts Medical Center

Completed

Improving Outcomes in Neonatal Abstinence Syndrome

Neonatal Abstinence Syndrome | Neonatal Opioid Withdrawal

United States
Assiut University

Unknown

Cyclizine Vs. Dexamethasone for Nausea and Vomiting Following Intrathecal Morphine in Cases of Cesarean Section

Spinal Anesthetics Causing Adverse Effects in Therapeutic Use
University Hospitals Cleveland Medical Center

Terminated

Efficacy of Buprenorphine on Postoperative Endodontic Analgesia (EBPEA)

Postoperative Pain

United States
Purdue Pharma LP

Completed

The Effect of Buprenorphine Delivered by Buprenorphine Transdermal System (BTDS) at Doses up to 80 Micrograms/Hour (mcg/hr) and Naltrexone on Electrocardiogram (ECG) Intervals in Healthy Volunteers

ECG Effects

United States
Stanford University

Completed

Patient-Driven Analgesic Protocol Selection for Post-Cesarean Pain Management

Postoperative Pain

United States
William Beaumont Hospitals

Completed

Psoas Compartment Block Versus Periarticular Local Anesthetic for Total Hip Arthroplasty

Osteoarthritis | Arthroplasty

United States
University Health Network, Toronto

Completed

Adductor Canal Block and Recovery After Total Knee Replacement Surgery (ACB in TKA)

Total Knee Arthroplasty

Canada
Federal University of the Valleys of Jequitinhonha...

Completed

Evaluation of Two Pharmacological Protocols for Pre-emptive Analgesia in Impacted Third Molar Surgery

Pain | Edema | Trismus

Brazil
Hvidovre University Hospital
Moberg Pharma, Sweden

Completed

Local Anesthetic Treatment of Oral Pain in Patients With Mucositis

Mucositis

Denmark
Hospital Universitario Dr. Jose E. Gonzalez

Completed

Non-anesthesiologist-administered Propofol During the Flexible Bronchoscopy

Conscious Sedation Failure During Procedure

Mexico
University of Rochester
Endo Pharmaceuticals

Terminated

Lumbar Stenosis Outcomes Research II (LUSTORII)

Lumbar Spinal Stenosis

United States
Korea University Anam Hospital

Unknown

Comparision Between Hemodynamic Response of Dexmedetomidine and Remifentanil on Anesthesia in Endoscopic Sinus Surgery

Hemodynamic Instability
Hallym University Medical Center

Completed

Comparison of Remifentanil and Dexmedetomidine for Monitored Anaesthesia Care During Vertebroplasty and Kyphoplasty

Fractures, Compression

Korea, Republic of
Turku University Hospital

Completed

Effects of Rifampicin on the Pharmacokinetics and Pharmacodynamics of Sublingual and Intravenous Buprenorphine

Healthy

Finland
AstraZeneca

Completed

Study in Healthy Volunteers to Investigate the Effects of Quinidine on the Pharmacokinetics of NKTR-118

Drug Induced Constipation

United States
Xijing Hospital

Unknown

The Clinical Research of Intranasal Dexmedetomidine Used in Plastic Surgery of Children

The Efficacy and Safety of Intranasal Dexmedetomidine
Zhujiang Hospital

Unknown

Effect of Induction and Maintenance of Anesthesia With Etomidate on Hemodynamics and Oxidative Stress in Diabetic Patients

Oxidative Stress | Anesthesia | Hemodynamics
Technical University of Munich

Completed

Rocuronium Dose Finding Study After Single-shot or Steady-state Propofol Anesthesia (ROSANNA)

Anesthesia | Neuromuscular Blockade

Germany
Guangzhou General Hospital of Guangzhou Military...

Completed

The Impact of Local Analgesia for Postoperative Analgesia in Posterior Thoracolumbar Operation

Pain

China
Janssen Research & Development, LLC

Completed

A Study to Assess the Relative Bioavailability of 4 Formulations of Fentanyl Transdermal System Compared Against DUROGESIC Fentanyl Transdermal Patch After Single Application in Healthy Volunteers

Healthy

Belgium
Jens Borglum Neimann

Completed

Ultrasound-guided Blocks for Ambulatory Knee Arthroscopy

Postoperative Pain | Postoperative Nausea and Vomiting | Postoperative Function Level

Denmark

3

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