Search clinical trials for: placebo for ezetimibe

Total 69305 results

Novartis Pharmaceuticals

Recruiting

Efficacy and Safety of Inclisiran as Monotherapy in Patients With Primary Hypercholesterolemia Not Receiving Lipid-lowering Therapy. (V-Mono)

Hypercholesterolemia

United States, Hungary, Mexico, Germany, Colombia
Organon and Co

Completed

IMPROVE-IT: Examining Outcomes in Subjects With Acute Coronary Syndrome: Vytorin (Ezetimibe/Simvastatin) vs Simvastatin (P04103)

Myocardial Infarction | Hypercholesterolemia
Organon and Co

Completed

A Study of the Efficacy and Safety of MK-0653H in Japanese Participants With Hypercholesterolemia (MK-0653H-832)

Hypercholesterolemia
University at Buffalo
Kaleida Health

Completed

To Study the Effect of Vytorin on Intracellular Lipid and Inflammation in Obese Subjects

Inflammation

United States
Sanofi
Regeneron Pharmaceuticals

Completed

Efficacy and Safety of Alirocumab (SAR236553/REGN727) Versus Ezetimibe in Patients With Hypercholesterolemia (ODYSSEY MONO)

Hypercholesterolemia

United States, Belgium, Finland, Netherlands
Organon and Co

Completed

A Clinical Trial to Assess the Efficacy and Safety of MK-0653C in Japanese Participants With Hypercholesterolemia (MK-0653C-383)

Hypercholesterolemia
Sanofi
Regeneron Pharmaceuticals

Completed

Efficacy and Safety of Alirocumab (SAR236553/REGN727) Versus Ezetimibe on Top of Statin in High Cardiovascular Risk Patients With Hypercholesterolemia (ODYSSEY COMBO II)

Hypercholesterolemia

United States, Canada, Denmark, France, Hungary, Israel, Korea, Republic of, Russian Federation, South Africa, Ukraine
Organon and Co

Completed

Efficacy and Safety Study of Ezetimibe (SCH 58235, MK-0653) in Addition to Atorvastatin in Participants With Coronary Heart Disease or Multiple Cardiovascular Risk Factors (P00693/MK-0653-030)

Hypercholesterolemia
Organon and Co

Completed

Ezetimibe (SCH 58235) Taken With Either Atorvastatin or Simvastatin in Participants With Familial Hypercholesterolemia (MK-0653-018)

Familial Hypercholesterolemia
NewAmsterdam Pharma

Recruiting

Study of Obicetrapib & Ezetimibe Fixed Dose Combination on Top of Maximum Tolerated Lipid-Modifying Therapies (TANDEM)

Dyslipidemias | Hypercholesterolemia | Familial Hypercholesterolemia | High Cholesterol | ASCVD

United States
Sanofi
Regeneron Pharmaceuticals

Completed

Evaluation of Alirocumab Versus Ezetimibe on Top of Statin in Asia in High Cardiovascular Risk Patients With Hypercholesterolemia (ODYSSEY EAST)

Hypercholesterolemia

China, India, Thailand
NewAmsterdam Pharma

Completed

Study to Evaluate the Effect of Obicetrapib in Combination With Ezetimibe as an Adjunct to HIS Therapy (ROSE2)

Dyslipidemias | Hypercholesterolemia | High Cholesterol

United States
Chong Kun Dang Pharmaceutical

Completed

Clinical Trial to Evaluate the Efficacy and Safety of CKD-391

Hyperlipidemia

Korea, Republic of
Organon and Co

Completed

Co-administration Study in Patients With Elevated Cholesterol and Coronary Heart Disease (0653-802)(COMPLETED)

Coronary Disease | Hypercholesterolemia
Organon and Co

Completed

An Investigational Drug Study in Patients With Elevated Cholesterol and Coronary Heart Disease (0653-804)(COMPLETED)

Coronary Disease | Hypercholesterolemia
Akeso
AD Pharmaceuticals Co., Ltd.

Completed

A Study of PCSK9 Inhibitor AK102 in Patients With Heterozygous Familial Hypercholesterolemia (HeFH)

Heterozygous Familial Hypercholesterolemia

China
Organon and Co

Completed

Co-administration Study in Patients With Elevated Cholesterol and Coronary Heart Disease (0653-803)

Coronary Disease | Hypercholesterolemia
University Clinical Centre of Republic of Srpska

Recruiting

Low-density Lipoprotein Cholesterol Reduction With State-of-the-art Therapy in Secondary Prevention and Major Cardiovascular Adverse Events: Republic of Srpska Registry (RS-ACS)

Dyslipidemias | Acute Coronary Syndrome

Bosnia and Herzegovina
Organon and Co

Completed

Investigational Drug Study in Patients With Elevated Cholesterol and Coronary Heart Disease (0653-801)

Coronary Disease | Hypercholesterolemia
Organon and Co

Completed

A Study to Evaluate the Effectiveness of Ezetimibe/Atorvastatin 10 mg/40 mg Combination Tablet Compared to Marketed Ezetimibe 10 mg and Atorvastatin 40 mg Tablets in Participants With High Cholesterol (MK-0653C-190 AM1)

Hypercholesterolemia
Karo Bio AB

Completed

LDL-Cholesterol Lowering Effect of KB2115 as Add on to Ezetimibe

Hypercholesterolemia

Sweden
Qpex Biopharma, Inc.
Biomedical Advanced Research and Development Authority

Completed

SAD/MAD Safety and PK Study of QPX9003 (Novel Polymyxin) in Normal Healthy Volunteers (QPX9003)

Bacterial Infections

United States
Organon and Co

Completed

A Study to Evaluate the Effectiveness of Ezetimibe/Atorvastatin 10 mg/20 mg Combination Tablet Compared to Marketed Ezetimibe 10 mg and Atorvastatin 20 mg Tablets in Participants With High Cholesterol (MK-0653C-185 AM1)

Hypercholesterolemia
Akeso
AD Pharmaceuticals Co., Ltd.

Completed

A Study of PCSK9 Inhibitor AK102 in Patients With Hypercholesterolemia

Hypercholesterolemia

China
Organon and Co
Schering-Plough

Completed

Ezetimibe and Simvastatin in Primary Hypercholesterolemia, Diabetes Mellitus Type 2, and Coronary Heart Disease (COMPLETED)

Coronary Disease | Diabetes Mellitus, Type 2 | Hypercholesterolemia
Organon and Co

Completed

To Evaluate Ezetimibe/Simvastatin and Niacin (Extended Release Tablet) in Patients With Type IIa or Type IIb Hyperlipidemia (0653A-091)(COMPLETED)

Hypercholesterolemia
VA Office of Research and Development

Terminated

Ezetimibe as a Safe and Efficacious Treatment for Chronic Hepatitis C

Chronic Hepatitis C

United States
Indiana University

Withdrawn

The Influence of Ezetimibe on Gallbladder Function

Chronic Acalculous Cholecystitis

United States
Radiant Research

Completed

Ezetimibe Reverse Cholesterol Transport (RCT) Pilot Study

Hypercholesterolemia

United States
Sanofi

Completed

A Study Evaluating the Safety and Efficacy of AVE5530 (4 Weeks) in Patients With Mild to Moderate Hypercholesterolemia

Hypercholesterolemia

Russian Federation, Turkey, Mexico, Hungary, Korea, Republic of, Chile
Boryung Pharmaceutical Co., Ltd

Recruiting

A Study to Evaluate the Efficacy and Safety of BR1017A and BR1017B Combination Therapy in Essential Hypertension Patients With Primary Hypercholesterolemia

Essential Hypertension | Primary Hypercholesterolemia

Korea, Republic of
Steno Diabetes Center Copenhagen
Department of Clinical Physiology, Nuclear Medicine and PET at Rigshospitalet... and other collaborators

Active, not recruiting

Kidney Fat in Type 2 Diabetes and the Effects of Ezetimibe (DiaKidZ)

Diabetes Mellitus, Type 2 | Diabetic Kidney Disease

Denmark
Organon and Co
Merck Sharp & Dohme LLC; Schering-Plough

Completed

Effects of Vytorin Versus Placebo in Subjects With Primary Hypercholesterolemia (Study P04420)

Hypercholesterolemia
Organon and Co

Completed

A Study to Evaluate the Effects of Ezetimibe (MK-0653) on the Postprandial (Following a Meal) Lipoprotein Response in Participants With Primary Hypercholesterolemia (High Cholesterol) (MK-0653-072)(COMPLETED)

Hypercholesterolemia
Materia Medica Holding

Completed

Clinical Trial of Efficacy and Safety of Anaferon for Children Liquid Dosage Form in the Treatment of Acute Upper Respiratory Infections

Acute Upper Respiratory Infections

Russian Federation
Alvogen Korea

Completed

Efficacy/Safety of DP-R207 Tablet Versus CRESTOR Tablet in Patients With Primary Hypercholesterolemia (ROSE)

Primary Hypercholesterolemia

Korea, Republic of
Organon and Co

Completed

Sitosterolemia Extension Study (0653-004)(COMPLETED)

Heart Disease | Lipid Metabolism, Inborn Errors
Organon and Co

Completed

Sitosterolemia Extension Study (0653-003)(COMPLETED)

Heart Disease | Lipid Metabolism, Inborn Errors
UCSF Benioff Children's Hospital Oakland
Merck Schering-Plough

Completed

Effects of Ezetimibe on the Absorption of Oxidized Cholesterol

Hypercholesterolemia

United States
Yonsei University
dotter

Recruiting

Comparative Study of Rosuvastatin/Ezetimib 20/10 mg and Atovastatin/Ezetimib 40/10 mg (TOLERANT Trial)

Coronary Artery Disease | Dyslipidemias

Korea, Republic of
Organon and Co

Completed

Effectiveness and Safety of Ezetimibe Added to Atorvastatin in Patients With High Cholesterol and Coronary Heart Disease (Study P03740)

Hypercholesterolemia | Coronary Heart Disease
Daewon Pharmaceutical Co., Ltd.

Completed

Clinical Trial to Evaluate the Efficacy and Safety of DW1125 and DW1125A

Hypercholesterolemia, Dyslipidemia

Korea, Republic of
Organon and Co

Completed

Retrospective Survey Evaluating the Effectiveness and Safety of Dual Inhibition Lipid-lowering in the Treatment of Dyslipidemia (Study P05171)(COMPLETED)

Dyslipidemia
Organon and Co
Merck Sharp & Dohme LLC

Completed

Pediatric Study to Evaluate the Efficacy and Safety of Ezetimibe Monotherapy in Children With Primary Hypercholesterolemia (P05522)

Primary Hypercholesterolemia
University of Manitoba

Completed

Creatine, Exercise and Inflammatory Markers in Knee Osteoarthritis

Osteoarthritis, Knee

Canada
Baylor College of Medicine
Merck Sharp & Dohme LLC

Completed

Effects of Ezetimibe, Simvastatin, and Vytorin on Reducing L5 a Subfraction of LDL in Patients With Metabolic Syndrome. (Merck-123)

Metabolic Syndrome

United States
Organon and Co

Completed

An Investigational Drug Study to Lower Non-Cholesterol Sterol Levels Associated With Sitosterolemia (0653-062)(COMPLETED)

Heart Disease | Lipid Metabolism, Inborn Errors
University of Oxford
National Health and Medical Research Council, Australia; Merck Sharp & Dohme... and other collaborators

Completed

Study of Heart and Renal Protection (SHARP)

Kidney Disease, Chronic

United Kingdom
Abbott

Completed

Safety and Efficacy Study Comparing ABT-335 Coadministered With Atorvastatin and Ezetimibe to Atorvastatin Coadministered With Ezetimibe in Subjects With Multiple Abnormal Lipid (Fat) Levels in the Blood

Dyslipidemias | Coronary Heart Disease | Mixed Dyslipidemia | Combined (Atherogenic) Dyslipidemia

United States
Esperion Therapeutics, Inc.

Completed

Bempedoic Acid + Ezetimibe Fixed-Dose Combination (FDC) Study in Patients With Type 2 Diabetes and Elevated LDL-C

Diabetes Mellitus, Type 2 | Diabetes | Cholesterolemia

United States

3

Subscribe