Search clinical trials for: posakonazole

Total 80 results

Merck Sharp & Dohme LLC

Terminated

A Study of the Safety, Tolerance, and Pharmacokinetics of Oral Posaconazole in Immunocompromised Children (P03579)

Fungal Infections
Merck Sharp & Dohme LLC

Completed

Posaconazole (MK-5592) Intravenous and Oral in Children With Invasive Aspergillosis (IA) (MK-5592-104)

Invasive Aspergillosis

Belgium, United States, Greece, Hungary, Israel, Italy, Korea, Republic of, Mexico, Peru, Russian Federation
Turku University Hospital

Completed

Effects of Posaconazole and Voriconazole on the Pharmacokinetics and Pharmacodynamics of Sublingual Buprenorphine (PosaBupre)

Pharmacokinetics and Pharmacodynamics of Sublingual Buprenorphine

Finland
Bayside Health
Merck Sharp & Dohme LLC

Unknown

Universal Prophylaxis Versus Pre-emptive Therapy With Posaconazole Post-Lung Transplant (UPPRITE)

Fungal Infection

Australia
Merck Sharp & Dohme LLC

Completed

Safety and Pharmacokinetics of Intravenous and Oral Posaconazole in Immunocompromised Children (MK-5592-097)

Neutropenia
Radboud University Medical Center
Merck Sharp & Dohme LLC; St. Antonius Hospital

Completed

Dosing Obese With Noxafil® Under a Trial (DONUT) (DONUT)

Morbid Obesity

Netherlands
Merck Sharp & Dohme LLC

Completed

Pharmacokinetics and Safety of Posaconazole Tablet in Participants at High Risk for Invasive Fungal Infections (MK-5592-065/P05615)

Fungal Infections
Merck Sharp & Dohme LLC

Recruiting

Posaconazole (MK-5592) Intravenous and Oral in Children (<2 Years) With Invasive Fungal Infection (MK-5592-127)

Invasive Fungal Infection

Israel, United States, Belgium, Greece, Peru, Poland, Mexico, Russian Federation
National Cancer Centre, Singapore
National Medical Research Council (NMRC), Singapore

Recruiting

The Role of Bexarotene in Inducing Susceptibility to Chemotherapy in Metastatic TNBC

Metastatic Triple-Negative Breast Carcinoma

Singapore
Nissan Chemical Industries

Completed

Efficacy and Safety of NM-702 Tablets for the Treatment of Intermittent Claudication

Intermittent Claudication | Peripheral Vascular Disease

United States
Bambino Gesù Hospital and Research Institute
Radboud University Medical Center; University of Exeter; Consorzio per Valutazioni...

Recruiting

A New Posaconazole Dosing Regimen for Paediatric Patients With Cystic Fibrosis and Aspergillus Infection (cASPerCF)

Cystic Fibrosis | Aspergillosis

Ireland, Spain, Netherlands, France, United Kingdom, Czechia, Germany, Greece, Italy, Portugal, Switzerland
Radboud University Medical Center
Universitaire Ziekenhuizen KU Leuven

Completed

Pharmacokinetics of Posaconazole (Noxafil®) as Prophylaxis for Invasive Fungal Infections (PIRAÑA)

Acute Graft Versus Host Disease | Allogeneic Stem Cell Transplant | Acute Myeloid Leucaemia | Myelo Dysplastic Syndrome

Belgium, Netherlands
University Medical Center Groningen

Completed

Effect of Inflammation on Pharmacokinetics of Posaconazole

Mycoses

Netherlands
Merck Sharp & Dohme LLC

Completed

Prophylaxis Trial of Posaconazole Versus Standard Azole Therapy for Neutropenic Patients (Study P01899)

Myelodysplastic Syndromes | Neutropenia | Leukemia, Myelocytic, Acute
Merck Sharp & Dohme LLC

Completed

Study of Posaconazole in the Treatment of Invasive Fungal Infections (Study P02095)

Mycoses
Milton S. Hershey Medical Center
National Cancer Institute (NCI)

Recruiting

Neuro-pharmacological Properties of Repurposed Posaconazole in Glioblastoma: A Phase 0 Clinical Trial

Glioblastoma | Glioblastoma Multiforme | Glioblastoma Multiforme, Adult | Glioblastoma Multiforme of Brain

United States
Radboud University Medical Center

Completed

Pharmacokinetics of Posaconazole in Children With Chronic Granulomatous Disease (CGD) (iPOD)

Chronic Granulomatous Disease

Netherlands
Hoffmann-La Roche

Completed

A Study of the Drug-Drug Interaction of RO5503781 and Posaconazole, the Relative Bioavailability of New Formulations of RO5503781 and the Food-Effect on the Pharmacokinetics of RO5503781 in Patients With Solid Tumors

Neoplasms

Canada, United States
Institute of Hematology & Blood Diseases Hospital
The Second Hospital of Hebei Medical University; Tianjin Medical University... and other collaborators

Not yet recruiting

Posaconazole for Pulmonary Fungal Infection Prophylaxis in Hematopoietic Stem Cell Transplantation Patients

Pulmonary Fungal Infection

China
Merck Sharp & Dohme LLC

Completed

PK/PD Study of Posaconazole for Empiric Treatment of Invasive Fungal Infections in Neutropenic Patients or Treatment of Refractory Invasive Fungal Infections (Study P01893)

Mycoses
Zhujiang Hospital
Guangdong Provincial People's Hospital

Completed

Population Pharmacokinetics and Safety of Oral Posaconazole in Children With Leukemia

Leukemia, Acute

China
Merck Sharp & Dohme LLC

Completed

Prophylaxis Trial in High Risk Allogenic Stem Cell Transplant Recipients With Graft vs. Host Disease

Mycoses
Postgraduate Institute of Medical Education and...

Recruiting

Amphotericin Versus Posaconazole for Pulmonary Mucormycosis

Mucormycosis; Pulmonary (Etiology)

India
Melbourne Health
Merck Sharp & Dohme LLC

Recruiting

Posaconazole Pharmacokinetics in Patients Receiving Chemotherapy or Stem Cell Transplants (POPULAR)

Fungal Infection | Pharmacokinetics | Invasive Aspergillosis | Prophylaxis | Invasive Candidiases | Posaconazole | Invasive Mycosis

Australia
Universitätsklinikum Hamburg-Eppendorf

Completed

Pharmacokinetic of Posaconazole in Critically Ill Patients

Critical Illness | Therapeutic Drug Monitoring

Germany
Memorial Sloan Kettering Cancer Center
Astellas Pharma US, Inc.

Completed

Posaconazole Versus Micafungin for Prophylaxis Against Invasive Fungal Infections During Neutropenia in Patients Undergoing Chemotherapy for Acute Myelogenous Leukemia, Acute Lymphocytic Leukemia or Myelodysplastic Syndrome

Myelodysplastic Syndrome | Acute Myelogenous Leukemia

United States
Merck Sharp & Dohme LLC

Withdrawn

Evaluation of Treatment and Prophylaxis of Invasive Fungal Infections in Immuncompromised Patients in Austria (Study P05532)(WITHDRAWN)

Mycoses
Merck Sharp & Dohme LLC

Completed

Safety and Efficacy of Posaconazole Oral Suspension in Usual Practice in Korea (P08547)

Fungal Infections
Cedars-Sinai Medical Center
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Recruiting

Pilot Study of Posaconazole in Crohn's Disease

Crohn Disease | CARD9 S12N Risk Allele

United States
Universidade Federal do Rio de Janeiro

Completed

Anti-mold Azole in the Prophylaxis for Invasive Fusariosis (Fusarproph)

Onychomycosis | Fusariosis

Brazil
University Health Network, Toronto

Not yet recruiting

Azoles Targeting Recurrent High Grade Gliomas

Brain Tumor, Recurrent | Cancer, Advanced | Glioma of Brain

Canada
Universitaire Ziekenhuizen KU Leuven
Institutul Clinic Fundeni

Completed

A New Dosing Regimen for Posaconazole Prophylaxis in Children Based on Body Surface Area

Hematological Malignancy

Belgium, Romania
Universitaire Ziekenhuizen KU Leuven
Merck Sharp & Dohme LLC

Completed

Posaconazole for the Prevention of Influenza-associated Aspergillosis in Critically Ill Patients (POSA-FLU)

Aspergillosis; Pulmonary, Invasive (Etiology)

Belgium, Netherlands
Merck Sharp & Dohme LLC

Completed

A Study of the Use of Oral Posaconazole (POS) in the Treatment of Asymptomatic Chronic Chagas Disease (P05267) (STOP CHAGAS)

Chagas Disease
Novartis
Mitsubishi Tanabe Pharma Corporation

Completed

Efficacy and Safety of FTY720 in Patients With Relapsing Multiple Sclerosis (MS)

Multiple Sclerosis

Japan
Erasmus Medical Center
ZonMw: The Netherlands Organisation for Health Research and Development; Stichting...

Terminated

Azole-echinocandin Combination Therapy for Invasive Aspergillosis (IA-DUET)

Invasive Aspergillosis

Belgium, Netherlands
F2G Biotech GmbH
The Clinical Trials Centre Cologne; Klinik für Hämatologie, Aachen; Medizinische...

Withdrawn

Safety and Pharmacokinetics of Oral F901318 (Fluconazole and Posaconazole) IN Aml Leukaemia (SAFEGUARDFP)

Acute Myeloid Leukemia
Scientific Institute San Raffaele

Unknown

Triple or Dual Antithrombotic Therapy After PCI (TRIDUAL-PCI) Coronary Intervention in Patients With Non-valvular Atrial Fibrillation. Real-world Italian Multicenter Registry (TRIDUAL-PCI) (TRIDUAL-PCI)

Myocardial Infarction | Coronary Disease | Atrial Fibrillation | Anticoagulant-induced Bleeding

Italy
Merck Sharp & Dohme LLC

Completed

Open Label Study of Posaconazole in the Treatment of Invasive Fungal Infections (Study P00041)

Mycoses
Children's Mercy Hospital Kansas City

Completed

Genetic Variation and Variability in Posaconazole Pharmacokinetics in Children

Fungal Infections

United States
Bayside Health

Unknown

Modified Release Posaconazole in Patients With Cystic Fibrosis

Cystic Fibrosis

Australia
King's College Hospital NHS Trust

Completed

King's Invasive Aspergillosis Study II

Myelodysplastic Syndromes | Leukemia, Myeloid, Acute | Bone Marrow Transplantation | Aplastic Anemia

United Kingdom
University of Pittsburgh
Schering-Plough

Terminated

Limited Access Protocol of Posaconazole in Invasive Fungal Infections Study PO2095

Fungal Infection

United States
Hospices Civils de Lyon

Recruiting

Pharmacokinetics Variability of Posaconazole (PCZ) and Its Glucuronide Metabolite During Induction and Consolidation Treatments in Patients With Acute Myeloid Leukemia (AML): a Covariate Analysis With the Tablets Formulation and Evaluation of the Potential Risk of Hepatotoxicity (Posa-Pk)

Leukemia, Myeloid, Acute

France
Seoul National University Hospital
Merck Sharp & Dohme LLC

Completed

Posaconazole Prophylaxis During ATG Treatment for hMDS/AA Patients

Myelodysplastic Syndromes | Fungal Infection | Aplastic Anemia

Korea, Republic of
Medical University of Graz
Merck Sharp & Dohme LLC

Completed

Posaconazole Prophylaxis for CAPA Prevention in Critically-Ill Patients (POSACOVID)

Aspergillosis | COVID-19 Respiratory Infection

Austria, France, Italy
National Institute of Allergy and Infectious Diseases...

Completed

Posaconazole to Treat Invasive Fungal Infections

Granulomatous Disease, Chronic | Infection | Job's Syndrome

United States
Taichung Veterans General Hospital
Merck Sharp & Dohme LLC

Withdrawn

Posaconazole as Salvage Therapy for Aspergillus Pulmonary Infection. (Posaconazole)

Clinical Infection
Merck Sharp & Dohme LLC

Approved for marketing

Single Patient Treatment of Posaconazole in Invasive Fungal Infections (Study P05113)

Mycoses
Royal Brisbane and Women's Hospital
The University of Queensland

Completed

Single Dose Population Pharmacokinetics of Intravenous Posaconazole in Critically Ill Patients (POSA)

Systemic Fungal Infections

Search clinical trials for: posakonazole

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