Search clinical trials for: prasugrel/bivalirudin

Total 259 results

Azienda Ospedaliera San Camillo Forlanini

Unknown

FIT (Fast Infarction Treatment): Complete Revascularization During Primary Percutaneous Coronary Intervention (PCI) Can be Achieved Safely With an Improved Clinical Outcome During the Indexed Hospitalization. (FIT)

Myocardial Infarction | Ischemia | Necrosis | Heart Failure | Stents

Italy
Istituto Clinico Sant'Ambrogio
Istituto Clinico Humanitas; Azienda Ospedaliera Niguarda Cà Granda; Centro Cardiologico...

Unknown

Bivalirudin/Prasugrel Versus Abciximab/Clopidogrel in Patients Presenting With STEMI

ST-Elevation Myocardial Infarction | Primary Percutaneous Coronary Intervention

Italy
Eli Lilly and Company
Daiichi Sankyo, Inc.

Completed

A Study of Prasugrel in Healthy Participants

Healthy Volunteers

United States
Maasstad Hospital
Daiichi Sankyo, Inc.; MicroPort Orthopedics Inc.; Research Maatschap Cardiologen...

Completed

CRUSHed vs. Uncrushed Prasugrel in STEMI Patients Undergoing PCI (CompareCrush)

Cardiovascular Diseases

Netherlands
Germano Di Sciascio
Cardiovascular Center Aalst, OLV Clinic, Aalst, Belgium; Department of Advanced... and other collaborators

Completed

Effects of Ticagrelor Versus Prasugrel on Coronary Microcirculation in Patients Undergoing Elective Percutaneous Coronary Intervention: Results of the PROtecting MICROcirculation During Coronary Angioplasty (PROMICRO)-3 Randomised Study (PROMICRO-3)

Coronary Artery Disease

Belgium
University of Patras

Completed

High (100mg) Versus Standard (60mg) Loading Dose of Prasugrel in Patients With ST-elevation Myocardial Infarction (STEMI), Undergoing Primary Percutaneous Coronary Intervention (PCI)

Platelet Reactivity

Greece
Gyeongsang National University Hospital

Completed

Fixed-dose vs. Phenotype-based PrAsugrel Dose to MATCH Therapeutic Zone in Asians With Acute Coronary Syndrome

Bleeding | Acute Coronary Syndrome | Platelet Thrombus

Korea, Republic of
University of Florida

Completed

Prasugrel Re-load Strategies

Coronary Artery Disease

United States
University of Milan

Completed

The Effect of Prasugrel on Bronchial Hyperreactivity and on Markers of Inflammation in Patients With Chronic Asthma (PRINA)

Chronic Asthma

Italy
Nanjing First Hospital, Nanjing Medical University

Completed

Safety and Efficacy of Prolonged Use of Bivalirudin 4 Hours After ePCI (COBER Study)

Coronary Heart Disease

China
Medstar Health Research Institute

Completed

The Effect of Reloading Prasugrel in a Patient Who Has Already Received a Loading Dose (LD) of Clopidogrel (SWITCH 600/60)

Acute Coronary Syndrome

United States
University of Florida

Completed

Pharmacological Effects of Crushing Prasugrel in STEMI Patients

Coronary Artery Disease

United States
VA Office of Research and Development

Completed

Prasugrel for Prevention of Early Saphenous Vein Graft Thrombosis

Coronary Artery Bypass

United States
Daiichi Sankyo Taiwan Ltd., a Daiichi Sankyo Company

Completed

Prasugrel Switching Study in Patients With Acute Coronary Syndrome (ACS) Who Underwent Percutaneous Coronary Intervention (PCI)

Acute Coronary Syndrome (ACS)

Taiwan
Eli Lilly and Company

Completed

A Relative Bioavailability Study of a Prasugrel Orally Disintegrating Tablet

Sickle Cell Disease

United States
Research Maatschap Cardiologen Rotterdam Zuid
Abbott Medical Devices

Recruiting

Comparison Of Reduced DAPT Followed by P2Y12 Inhibitor Monotherapy With Prasugrel vs stAndard Regimen in STEMI Patients

ST Elevated Myocardial Infarction | Dual Antiplatelet Therapy

Netherlands, Germany, Italy
Eli Lilly and Company

Completed

Study of Prasugrel in Korean Healthy Male Volunteers

Healthy Volunteers

Korea, Republic of
Ottawa Heart Institute Research Corporation
Spartan Bioscience Inc.

Completed

ReAssessment of Anti-Platelet Therapy Using an InDividualized Strategy Based on GENetic Evaluation (RAPID GENE)

Acute Coronary Syndrome | Percutaneous Coronary Intervention | Stable Coronary Artery Disease

Canada
Eli Lilly and Company
Daiichi Sankyo Co., Ltd.

Completed

An Assessment of Prasugrel on Healthy Adults and Sickle Cell Adults

Anemia, Sickle Cell

United Kingdom
Eli Lilly and Company
Daiichi Sankyo, Inc.

Terminated

A Study of Prasugrel in Pediatric Participants With Sickle Cell Disease (SCD)

Sickle Cell Disease

United Arab Emirates, Italy, United States, Egypt, United Kingdom, Belgium, Turkey, Brazil, Canada, Ghana, Kenya, Lebanon, Oman, Saudi Arabia
Rigshospitalet, Denmark

Completed

Time to Thrombocytic Inhibition After Supine and Upright Ingestion of Efient

ST-elevation Myocardial Infarction | Ischemic Heart Disease | Heart Disease

Denmark
Eli Lilly and Company
Daiichi Sankyo, Inc.

Completed

Prasugrel Versus Placebo in Adult Sickle Cell Disease

Sickle Cell Anemia

United States
Eli Lilly and Company
Daiichi Sankyo Co., Ltd.

Completed

A Comparison of Prasugrel at PCI or Time of Diagnosis of Non-ST Elevation Myocardial Infarction (ACCOAST)

Acute Coronary Syndromes

Israel, Italy, Germany, Belgium, Poland, France, Austria, Netherlands, Turkey, Hungary, Lithuania, Romania, Canada, Slovakia, Czech Republic, Finland, Latvia, Portugal, Sweden
Eli Lilly and Company
Daiichi Sankyo, Inc.

Completed

A Study of Prasugrel in Pediatric Participants With Sickle Cell Disease (Crescent)

Sickle Cell Disease

United States
David Antoniucci
A.R. CARD Onlus Foundation

Terminated

BLeeding Events and Maintenance DoSe of PraSugrel (BLESS)

Acute Coronary Syndrome | Adverse Reaction to Antiplatelet Agent

Italy
Azienda Ospedaliera Universitaria Integrata Verona
University of Milan

Unknown

Prasugrel in Severe COVID-19 Pneumonia (PARTISAN)

Thrombosis | COVID19

Italy
Deutsches Herzzentrum Muenchen

Unknown

Efficacy Study of Combined Prasugrel and Bivalirudin Versus Clopidogrel and Heparin in Myocardial Infarction (BRAVE-4)

Myocardial Infarction

Germany
Ottawa Heart Institute Research Corporation
Spartan Bioscience Inc.

Completed

Pharmacogenetic Approach to Anti-platelet Therapy for the Treatment of ST-segment Elevation Myocardial Infarction (STEMI) (RAPID STEMI)

STEMI

Canada
The Medicines Company

Completed

Angiomax in Patients With HIT/HITTS Type II Undergoing Off-Pump Coronary Artery Bypass Grafting (CABG) (CHOOSE)

Thrombosis | Thrombocytopenia | Cardiac Disease | Coronary Artery Bypass Surgery

United States
The Medicines Company

Completed

Angiomax in Patients With HIT/HITTS Type II Undergoing CPB (HIT/TS)

Cardiovascular Disease | Coronary Artery Bypass Surgery

United States
The Medicines Company

Withdrawn

Bivalirudin PCI Registry in Heparin Induced Thrombocytopenia/Heparin Induced Thrombocytopenia and Thrombosis Syndrome (HIT/HITTS) Patients

Heparin-Induced Thrombocytopenia | Heparin-induced Thrombocytopenia and Thrombosis Syndrome

United States
The Medicines Company

Completed

Bivalirudin as a Procedural Anticoagulant in Pediatrics

Cardiology
The Medicines Company

Completed

Study Of Angiomax In Infants Under Six Months With Thrombosis

Thrombosis

United States
Asan Medical Center

Unknown

Clinical Trial to Characterize Pharmacokinetic-pharmacodynamic (PKPD) of Prasugrel 10 mg or 30 mg in Healthy Volunteers (PRAS-AM)

Healthy

Korea, Republic of
Eli Lilly and Company
Daiichi Sankyo, Inc.

Completed

Effect of Prasugrel on Platelets After One Week in Patients Already Taking Clopidogrel After a Cardiac Event (SWAP)

Acute Coronary Syndrome | Coronary Arteriosclerosis

United States
Italian Society of Invasive Cardiology
Eustrategy

Unknown

Minimizing Adverse Haemorrhagic Events by TRansradial Access Site and Systemic Implementation of angioX (MATRIX)

STEMI | Acute Coronary Syndromes | NSTEMI

Italy
The Medicines Company

Completed

Bivalirudin in Patients With Acute Myocardial Infarction (AMI) Undergoing Primary PCI

Myocardial Infarction

United States
Hamad Medical Corporation

Unknown

Anticoagulation in Patients Suffering From COVID-19 Disease The ANTI-CO Trial

Anticoagulation in COVID-19 ARDS

Qatar
University Hospital, Geneva

Completed

Ex-Vivo Reversion of Platelet Inhibition Induced by Prasugrel

Acquired Platelet Disorder

Switzerland
The Medicines Company

Completed

Anticoagulant Therapy With Bivalirudin in the Performance of Percutaneous Coronary Intervention in Patients With Heparin-Induced Thrombocytopenia (AT BAT, First Inning)

Thrombosis | Heparin-Induced Thrombocytopenia

United States
Chinese PLA General Hospital

Unknown

Bivalirudin in Stable Ischemic Heart Disease Patients Undergoing PCI

Coronary Disease

China
University of Pecs

Completed

Prasugrel Versus Clopidogrel to TREAT High Platelet Reactivity (TREAT-HPR)

Acute Coronary Syndrome

Hungary
Eli Lilly and Company

Completed

A Trial of CS-747 (Prasugrel) Compared With Clopidogrel in Patients Undergoing Percutaneous Coronary Intervention (PCI)

Heart Diseases | Cardiovascular Diseases

United States, Canada
Taichung Veterans General Hospital

Completed

Effects of Cranberry Extractive on the Lipid Profiles in Subjects With Type 2 Diabetes

Type 2 Diabetes

Taiwan
The Medicines Company

Completed

Comparison of Angiomax Versus Heparin in Acute Coronary Syndromes (ACS)

Myocardial Infarction | Acute Disease | Unstable Angina

United States
Seoul National University Hospital
Boston Scientific Korea Co. Ltd; Dio; Terumo Corporation; Abbott

Unknown

Harmonizing Optimal Strategy for Treatment of Coronary Artery Diseases Trial - Comparison of REDUCTION of PrasugrEl Dose & POLYmer TECHnology in ACS Patients (HOST REDUCE POLYTECH RCT Trial)

Acute Coronary Syndrome

Korea, Republic of
Elliot Israel, MD
Brigham and Women's Hospital

Completed

Therapeutic Control of Aspirin-Exacerbated Respiratory Disease (Aspirin) (Aspirin)

Asthma, Aspirin-Induced | Aspirin Exacerbated Asthma

United States
Nycomed

Withdrawn

RIAPRE - Non-interventional Registry of Anticoagulation Treatment (BI-006-IT)

Coronary Disease
Changhai Hospital
Wuhan University; Qilu Hospital of Shandong University; The First Affiliated... and other collaborators

Unknown

Efficacy and Safety of Bivalirudin Versus Heparin During Coil Embolization in Patients With Ruptured Intracranial Aneurysms (BUILD)

Subarachnoid Hemorrhage, Aneurysmal
Assistance Publique - Hôpitaux de Paris
Eli Lilly and Company; Daiichi Sankyo, Inc.; Stentys; Accumetrics, Inc.; Allies in...

Completed

Tailored Antiplatelet Therapy Versus Recommended Dose of Prasugrel (ANTARCTIC)

Acute Coronary Syndrome

France

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