Search clinical trials for: preservative-free parenteral treprostinil

Total 129 results

AOP Orphan Pharmaceuticals AG

Not yet recruiting

Investigational Trial to Evaluate Safety and Tolerability of Treprostinil in Children Diagnosed With PAH

Pulmonary Arterial Hypertension

Spain, Austria, France, Hungary
United Therapeutics

Withdrawn

Safety of Transition From Selexipag to Remodulin® Then Oral Treprostinil in Symptomatic Adult PAH

Pulmonary Arterial Hypertension
United Therapeutics
Lung Biotechnology PBC

Recruiting

A Study of a Mean Pulmonary Artery Pressure-Targeted Approach With Early and Rapid Treprostinil Therapy to Reverse Right Ventricular Remodeling in Participants With Pulmonary Arterial Hypertension (ARTISAN)

Pulmonary Arterial Hypertension

United States
Direction Centrale du Service de Santé des Armées

Recruiting

Preventive TREatment of Dry Eye in Patients Receiving Repeated Intravitreal Injections for Age-related Macular Degeneration (TREDIA)

Age-Related Macular Degeneration | Dry Eye Syndromes

France
Association for Innovation and Biomedical Research...
European Vision Institute Clinical Research Network

Completed

Intraocular Pressure and Tolerability Study of Preservative-free Prostaglandins (Bimatoprost and Latanoprost) on Glaucoma and Ocular Hypertension: European, Multicentric, Investigator-led, Single Masked Study (SPORT)

Ocular Hypertension | Glaucoma

United Kingdom, Switzerland, Belgium, Italy, Portugal, Austria
Oregon Health and Science University

Active, not recruiting

Chloroprocaine Lavage to Improve Outcomes Related to Operative Cesarean Delivery (CLOR-PRO)

Cesarean Section

United States
Ifocus Oyeklinikk
The Research Council of Norway

Recruiting

Metabolomic Profile in Dry Eye Syndrome Patients.

Cataract | Dry Eye Syndromes

Norway
Tun Hussein Onn National Eye Hospital

Completed

Tafluprost Preservative Free Switch Study

Primary Open Angle Glaucoma | Ocular Hypertension | Glaucoma

Malaysia
Gina Rogers

Withdrawn

Tears Substitutions and Their Effects on Higher Order Aberrometery

Dry Eye Syndrome

United States
Merck Sharp & Dohme LLC

Completed

Preservative-Free Tafluprost (MK-2452) for the Treatment of Open-Angle Glaucoma or Ocular Hypertension (MK-2452-002)

Ocular Hypertension | Glaucoma
Santen Oy

Completed

A Study to Evaluate Pharmacokinetics of Tafluprost Ophthalmic Solution (0.0015%) in Pediatric Patients With Glaucoma or Ocular Hypertension

Ocular Hypertension | Glaucoma

United Kingdom, United States
Adolfo Daniel Rodriguez-Carrizalez
Hospital Civil de Guadalajara

Recruiting

Effect of Topical Antioxidants in Dry Eye Disease and Diabetic Retinopathy

Diabetic Retinopathy | Dry Eye Syndromes | Oxidative Stress | Tear Film Deficiency

Mexico
GlaxoSmithKline

Completed

Immuno & Safety Study of GSK Biologicals' Thio or Preservative Free Hepatitis B Vaccine in Subjects Aged 11-15 Yrs

Hepatitis B

Belgium, Ukraine, Australia
Universidade Estadual Paulista Júlio de Mesquita...

Unknown

Influence of Enamel Matrix Derivative (Emdogain®) on Palate Wound Healing.

Palatal Wound

Brazil
Boston Children's Hospital

Completed

Nutrition Support in Pediatric Stem Cell Transplantation

Hematopoietic Stem Cell Transplantation
Radboud University Medical Center

Completed

Immune Modulation by Parenteral Lipids

Infections | Total Parenteral Nutrition

Netherlands
Alcon Research

Completed

Systane® Complete Preservative Free Lubricant Eye Drops

Dry Eye

Canada
Alexandria University

Completed

Preservative-free Tafluprost Eye Drops in Newly Diagnosed Patients With Glaucoma

Glaucoma

Egypt
Alcon Research

Recruiting

Systane® Hydration PF and Systane® Hydration Preserved

Dry Eye

Canada
Santen Oy

Completed

Pharmacokinetics, Safety and Tolerability of the Preservative-free Fixed Dose Combination of Tafluprost 0.0015% and Timolol 0.5% Eye Drops

Healthy Volunteers

Finland
Stony Brook University

Unknown

Study to Examine Pain Relief With Supplemental Intrathecal Morphine in TKA Patients

Acute Pain

United States
Laboratorios Sophia S.A de C.V.

Completed

Safety and Tolerability of PRO-087 Versus Xyel Ofteno® and Systane Ultra®, on the Ocular Surface of Healthy Subjects (PRO-087/I)

Dry Eye Syndromes | Lubricant Allergy | Tear Disorder

Mexico
Universidade Estadual Paulista Júlio de Mesquita...

Completed

Photobiomodulation of Palatal Donor Site After Free Gingival Graft Removal

Palatal Wound

Brazil
Novartis
Novartis Vaccines

Completed

Safety and Immunogenicity of Preservative Free Inactivated Split Influenza Vaccine, Using the Strain Composition 2006/2007 in Non-Elderly Adult and Elderly Subjects

Influenza

Germany
Yonsei University

Completed

Clinical Effects of Diquas-S for Patients With Dry Eye After Cataract Surgery

Dry Eye | Cataract Surgery

Korea, Republic of
CHA University
Samil Pharmaceutical Co., Ltd.

Completed

Comparison of Efficacy and Ocular Surface Disease Assessment Between Monoprost and BAK-preserved Latanoprost

Ocular Hypertension | Glaucoma

Korea, Republic of
Rigshospitalet, Denmark
Laboratoires Thea

Recruiting

Effect of Benzalkonium Chloride Preserved and Preservative-free Latanoprost Eye Drops on Conjunctival Goblet Cells

Ocular Hypertension | Glaucoma

Denmark
Universidade Estadual Paulista Júlio de Mesquita...

Unknown

Influence of Electrical Stimulation on Palatal Wound Healing.

Palatal Wound

Brazil
Alcon Research

Recruiting

Systane® Ultra Preservative Free Lubricant Eye Drops

Dry Eye

Canada
Tufts Medical Center

Recruiting

Predicting the Success of Dry Eye Disease Interventions Using Clinical Tests (PreDICT)

Dry Eye

United States
Medical University of Vienna

Recruiting

Latanoprost Preserved Versus Unpreserved: Effect on Tear Film Thickness as Measured With OCT

Ocular Hypertension | Glaucoma

Austria
University of Iowa

Completed

Cool vs Room-temperature Artificial Tears

Eye Pain | Ocular Surface Disease | Cystoid Macular Edema | Central Retinal Vein Occlusion With Macular Edema | Diabetic Retinopathy With Macular Edema of Both Eyes (Diagnosis) | Exudative Age-Related Macular Degeneration, Unspecified Eye | Dry Eye Sensation

United States
Sanofi Pasteur, a Sanofi Company

Completed

Safety and Immunogenicity Testing of Influenza Vaccine in Healthy Children 2 Months and 6 Months of Age

Influenza

United States
Alcon Research

Completed

Clinical Outcomes Following Treatment With Systane® Balance in Dry Eye Subjects

Dry Eye
Tecnoquimicas

Recruiting

Management of the Ocular Surface With Preservative-Free Lubricants in Patients With Dry Eye

Dry Eye Disease

Colombia
Wake Forest University Health Sciences

Terminated

Efficacy of Intrathecal Oxytocin in Patients With Neuropathic Pain

Neuropathic Pain

United States
University of Florida

Completed

Effects of Carboxymethylcellulose Artificial Tears on the Eye Microbiome

Dry Eye Syndromes

United States
Universitaire Ziekenhuizen KU Leuven
Laboratoires Thea

Recruiting

Comparison of Treatment With Preservative-free Dexamethasone 0.1% (Monofree Dexamethason) and Diclofenac 0.1% (Dicloabak) Eye Drops Versus Preserved Dexamethasone 0.1% (Maxidex) and Diclofenac 0.1% (Voltaren Ophtha) Eye Drops After Cataract Surgery (GIST)

Age-related Cataract

Belgium
AbbVie

Recruiting

An Observational Study to Assess Next Generation Emulsion Preservative Free Eye Drops (NGE-UD) on Dry Eye Symptoms and Quality of Life of Adult Participants With Mild to Moderate Dry Eye Disease (DED)

Dry Eye

United States
Universitaire Ziekenhuizen KU Leuven
Allergan

Unknown

Investigation of IOP and Tolerability of Bimatoprost 0.01% and Tafluprost Unit Dose Preservative Free 15 Microgram/ml (SPORTII)

Ocular Hypertension | Glaucoma

Belgium, Austria, Italy, Switzerland, United Kingdom
University of Duhok

Not yet recruiting

Parenteral Versus Combined Parenteral With Vancomycin-soaked Graft in ACL Reconstruction

Infection, Bacterial
Spektrum Center of Clinical Ophthalmology
Wrocław University of Science and Technology

Active, not recruiting

Eye Surface Properties After Using Dexamethasone Drops With and Without Preservatives in Patients After Cataract Surgery (EyeSurface)

Healing Wound | Cataract | Surgical Injury

Poland
GlaxoSmithKline

Completed

Investigational Parkinson's Disease In Patients Not Well Controlled On L-dopa

Parkinson Disease

United States, France, Spain, Poland, Belgium, Hungary, Germany, Italy, Czech Republic
Alcon Research

Completed

Clinical Evaluation of Systane® ULTRA Compared to OPTIVE® in Ocular Surface Staining

Dry Eye Syndrome
Icahn School of Medicine at Mount Sinai

Completed

Neuraxial Preservative Free Morphine for Normal Spontaneous Vaginal Delivery

Postpartum Depression | Opioid Consumption | Postpartum Pain

United States
Chang Gung Memorial Hospital

Unknown

Effect of Preservative-free Low-dose Hyaluronic Acid-containing Salt Solution on Dry Eye Disease

Dry Eye

Taiwan
Allergan

Completed

Safety, Efficacy, and Acceptability Study of an Eye Drop Formulation in Subjects With Dry Eye Disease

Dry Eye Syndromes

United States
Santen Pharmaceutical Co., Ltd.

Completed

A Study of DE-111A on the Treatment of Open Angle Glaucoma or Ocular Hypertension

Open-angle Glaucoma, Ocular Hypertension

China
Assiut University

Completed

Preservative-free Topical Anesthetics for Post-PRK Pain

Myopia

Egypt
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI)

Withdrawn

Anakinra as a Rescue Treatment for Allergic Inflammation

Asthma, Allergic

3

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