Search clinical trials for: Standard of care

Total 171085 results

International Maternal Pediatric Adolescent AIDS...
National Institute of Allergy and Infectious Diseases (NIAID); Eunice Kennedy...

Completed

Antiviral Responses to NNRTI-Based vs. PI-Based ARV Therapy in HIV Infected Infants Who Have or Have Not Received Single Dose NVP for Prevention of Mother-to-Child Transmission of HIV (P1060)

HIV Infections

Uganda, India, Malawi, South Africa, Tanzania, Zambia, Zimbabwe
National Cancer Institute (NCI)

Completed

Phase II Study of Fluorine-18 3'-Deoxy-3'-Fluorothymidine (F-18-FLT) in Invasive Breast Cancer

Stage IIIA Breast Cancer | Stage IIIB Breast Cancer | Stage IIB Breast Cancer | Stage IIIC Breast Cancer

United States
University Medicine Greifswald

Completed

Effects of 500 mg Immediate Release and Extended Release Methylnaltrexone on Loperamide-induced Delay of the Oro-cecal and Whole-gut Transit Time in Healthy Subjects (LOP-MNTX-2009)

Intestinal Obstruction

Germany
National Cancer Institute (NCI)

Terminated

Bortezomib and Dexamethasone With or Without Lenalidomide in Treating Patients With Multiple Myeloma Previously Treated With Dexamethasone

Stage I Multiple Myeloma | Stage II Multiple Myeloma | Stage III Multiple Myeloma

United States, South Africa
Bayer

Completed

Cycle Control and Safety of E2-DRSP

Contraceptive, Oral, Hormonal

Germany
University of Parma

Completed

Duration of Sciatic Nerve Block After Injection of Local Anesthetic In or Around the Nerve

Postoperative Pain | Orthopedic Surgical Procedures

Italy
Instituto Nacional de Ciencias Medicas y Nutricion...
University of Pennsylvania; University of Witwatersrand, South Africa; Case Western... and other collaborators

Unknown

Maraviroc (CCR5) Antagonism to Decrease the Incidence of the Immune Reconstitution Inflammatory Syndrome in HIV-Infected Patients (CADIRIS)

HIV Infections | HIV | Immune Reconstitution Inflammatory Syndrome

Mexico, United States, South Africa
Alcon Research

Completed

A Clinical Safety and Efficacy Comparison of NEVANAC 0.1% to Vehicle After Cataract Surgery in Diabetic Retinopathy Patients

Macular Edema
Centers for Disease Control and Prevention

Terminated

Efficacy of Artemisinin Combination Therapies for the Treatment of Uncomplicated P. Vivax in Pregnancy in Brazil (PAACT-PV) (PAACT-PV)

Plasmodium Vivax Malaria

Brazil
Instituto Valenciano de Infertilidad, IVI VALENCIA

Unknown

Comparison Between Natural and Artificial Cycle in Recipient Oocyte Patients

Infertility

Spain
University of Campania "Luigi Vanvitelli"

Completed

5 Day Concomitant Versus 10 Day Sequential Therapy for Eradication of H. Pylori Infection

Helicobacter Pylori Infection

Italy
Göteborg University

Completed

A Study on Antiretroviral Therapy (ART) Naïve Patients On Different Regimens to Treat Hiv (NORTHIV)

HIV

Sweden
Bristol-Myers Squibb

Completed

A Comparison of BMS-232632 With Efavirenz, Each in Combination With Zidovudine-Lamivudine

HIV Infections

United States, Chile, Switzerland, Austria, Belgium, Italy, United Kingdom, France, Germany, Guatemala, Spain, Puerto Rico, Canada, Peru, Thailand, Israel, Portugal, Russian Federation, South Africa, Costa Rica, Hungary, Malaysia, P... and more
Yunnan AIDS Care Center

Unknown

Safety and Efficacy of Raltegravir+TDF+3TC in HBV/HIV Co-infected Patients

HIV Infections | HBV Coinfection

China
French National Agency for Research on AIDS and...
Merck Sharp & Dohme LLC; Janssen-Cilag Tibotec

Completed

Clinical Trial to Assess the Efficacy of Darunavir/Ritonavir (DRV/r), Etravirine (ETV) and Raltegravir (MK-0518) in HIV Patients With Resistant Viruses (ANRS139 TRIO)

HIV Infections

France
Tuberculosis Research Centre, India

Unknown

Short Course Intermittent Regimens for the Treatment of HIV-Associated Tuberculosis

Tuberculosis | Human Immunodeficiency Virus Infections

India
Eli Lilly and Company

Completed

Study of Hot Flashes and Night Sweats in Postmenopausal Women Receiving Combination Raloxifene and Oral Estrogen

Vasomotor Symptoms | Endometrial Safety

United States
Bradley Nindl
U.S. Army Medical Research and Development Command

Not yet recruiting

Adaptions and Resiliency to Multi-Stressor OpeRations (ARMOR)

Hypogonadism | Musculoskeletal Injury

United States
Beijing Chest Hospital
National Medical Center for Infectious Diseases

Recruiting

Innovating Shorter, All- Oral, Precised, Individualized Treatment Regimen for Rifampicin Resistant Tuberculosis：Contezolid, Delamanid and Bedaquiline Cohort (INSPIRE-CODA)

Pulmonary Tuberculosis | Rifampicin-resistant Tuberculosis

China
University of Missouri-Columbia

Recruiting

CAT BITE Antibiotic Prophylaxis for the Hand/Forearm (CATBITE) (CATBITE)

Infection, Bacterial | Anti-bacterial Agents | Hand Injuries | Arm Injury | Cat Bite

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Transarterial Chemoembolization for the Treatment of Lung Cancer

Lung Non-Small Cell Carcinoma | Mediastinal Neoplasm | Pleural Neoplasm

United States
National Cancer Institute (NCI)

Recruiting

Testing the Safety of the Anti-cancer Drugs Tazemetostat and Belinostat in Patients With Lymphomas That Have Resisted Treatment

Refractory B-Cell Non-Hodgkin Lymphoma | Refractory T-Cell Non-Hodgkin Lymphoma | Recurrent B-Cell Non-Hodgkin Lymphoma | Recurrent Transformed Non-Hodgkin Lymphoma | Recurrent Non-Hodgkin Lymphoma | Refractory Non-Hodgkin Lymphoma | Recurrent T-Cell Non-Hodgkin Lymphoma | Recurrent Primary Cutaneous... and other conditions

United States
GlaxoSmithKline
Biological E. Limited

Recruiting

Safety and Immunogenicity of a Novel Conjugate Vaccine Against Salmonella Typhi and Salmonella Paratyphi A in Healthy Adults

Typhoid Fever

Belgium
Amsterdam UMC, location VUmc

Not yet recruiting

Alternative Dosing Scheme of Pomalidomide 4 mg Every Other Day Versus Pomalidomide 2 mg and 4 mg Every Day; the POMAlternative Study (POMAlternative)

Multiple Myeloma | Multiple Myeloma in Relapse | Multiple Myeloma, Refractory
National Institute of Allergy and Infectious Diseases...

Recruiting

Trial of a Six-Month Regimen of High-Dose Rifampicin, High-Dose Isoniazid, Linezolid, and Pyrazinamide Versus a Standard Nine-Month Regimen for the Treatment of Adults and Adolescents With Tuberculous Meningitis

Tuberculous Meningitis

South Africa, Zimbabwe, India, Kenya, Malawi, Mexico, Peru, Brazil, Philippines, Tanzania, Thailand, Vietnam
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

TMLI and Alemtuzumab for Treatment of Sickle Cell Disease

Sickle Cell Disease

United States
National Cancer Institute (NCI)

Recruiting

Testing the Addition of an Anti-cancer Drug, Ipatasertib, to the Usual Immunotherapy Treatment (Pembrolizumab) in Patients With Recurrent or Metastatic Squamous Cell Cancer of the Head and Neck

Head and Neck Squamous Cell Carcinoma | Recurrent Head and Neck Squamous Cell Carcinoma | Recurrent Hypopharyngeal Squamous Cell Carcinoma | Recurrent Laryngeal Squamous Cell Carcinoma | Recurrent Oral Cavity Squamous Cell Carcinoma | Recurrent Oropharyngeal Squamous Cell Carcinoma | Metastatic... and other conditions

United States
National Cancer Institute (NCI)

Recruiting

Cancer Preventive Vaccine Nous-209 for Lynch Syndrome Patients

Lynch Syndrome

United States, Puerto Rico
National Cancer Institute (NCI)

Recruiting

EA2176: Phase 3 Clinical Trial of Carboplatin and Paclitaxel +/- Nivolumab in Metastatic Anal Cancer Patients

Anal Canal Cloacogenic Carcinoma | Metastatic Anal Squamous Cell Carcinoma | Recurrent Anal Squamous Cell Carcinoma | Stage III Anal Cancer AJCC v8 | Stage IV Anal Cancer AJCC v8 | Unresectable Anal Squamous Cell Carcinoma | Anal Basaloid Squamous Cell Carcinoma

United States
Ulrik Lassen
GlaxoSmithKline; Pfizer; Roche Pharma AG

Recruiting

ProTarget - A Danish Nationwide Clinical Trial on Targeted Cancer Treatment Based on Genomic Profiling (ProTarget)

Neoplasms | Cancer | Tumors | Neoplasia

Denmark
National Taiwan University Hospital
Ministry of Science and Technology, Taiwan

Recruiting

Efficacies of HDDT With or Without Bismuth vs Amoxicillin-metronidazole BQT for First-line H Pylori Eradication

Helicobacter Pylori Infection

Taiwan
Centre Hospitalier Universitaire, Amiens

Recruiting

CLArithromycin Versus AZIthromycin in the Treatment of Mycobacterium Avium Complex (MAC) Lung Infections (CLAZI)

Mycobacterium Avium Complex | Lung Infection

France
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

Very Early Intensive Treatment of Infants Living With HIV to Achieve HIV Remission

HIV Infection

Puerto Rico, United States, Argentina, Brazil, South Africa, Uganda, Zambia, Haiti, Kenya, Malawi, Tanzania, Thailand, Zimbabwe
Mural Oncology, Inc
Merck Sharp & Dohme LLC

Active, not recruiting

Phase 3 Study of Nemvaleukin Alfa in Combination With Pembrolizumab in Patients With Platinum-Resistant Epithelial Ovarian Cancer (ARTISTRY-7) (ARTISTRY-7)

Fallopian Tube Cancer | Platinum-resistant Ovarian Cancer | Primary Peritoneal Cancer

Canada, United States, France, Spain, Korea, Republic of, Austria, United Kingdom, Taiwan, Germany, Belgium, Czechia, Australia, Singapore, Italy
M.D. Anderson Cancer Center

Completed

An Investigational Scan (rh PSMA 7.3 PET/MRI) for the Detection of Recurrent Disease and Aid in Radiotherapy Planning in Biochemically Recurrent Prostate Cancer

Biochemically Recurrent Prostate Carcinoma | Prostate Adenocarcinoma | Localized Prostate Carcinoma

United States
Mylan Pharmaceuticals Inc

Completed

Bioequivalence and Wear Study of Mylan Fentanyl Transdermal System 25 µg/h and Mylan Fentanyl Transdermal System

Healthy

United States
University Hospital, Linkoeping
Linkoeping University

Suspended

Drug Exposure and Safety of a Shorter Tuberculosis Treatment Based on High-Dose Rifampicin and Pyrazinamide (HIGHSHORT-RP)

Tuberculosis, Pulmonary

Sweden
Technical University of Munich

Completed

Dual Therapy With Boosted Darunavir + Dolutegravir (Dualis)

HIV-Infection

Germany
University of Giessen
Indonesian Directorate General of Higher Education

Completed

Fermented Soybean Supplementation Among Active Pulmonary Tuberculosis Patients With Standard Therapy in Indonesia (FSS)

Body Weight Changes | Motor Activity | Pulmonary Tuberculosis
Washington University School of Medicine
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Chloroquine to Treat People With Metabolic Syndrome Aim2 (ARCH-MS) (ARCH-MS)

Hypertension | Overweight | Dyslipidemias | Prediabetic State | Metabolic Syndrome X

United States
Sheba Medical Center

Completed

Corticosteroids+5-aminosalicylic Acid Compared to Corticosteroids in the Treatment of Moderate-severe Ulcerative Colitis

Ulcerative Colitis

Israel, China, France, Greece, Italy, Korea, Republic of, Serbia
Sanofi Pasteur, a Sanofi Company

Completed

Study of DTwP-HepB-Hib-IPV (SHAN6™) Vaccine Administered Concomitantly With Routine Pediatric Vaccines to Healthy Infants and Toddlers in Thailand

Pertussis Immunisation | Diphtheria Immunisation | Tetanus Immunisation | Pneumococcal Immunisation | Hepatitis B Immunisation | Polio Immunisation | Haemophilus Influenzae Type B Immunisation | Rotavirus Immunisation

Thailand
Teva Branded Pharmaceutical Products R&D, Inc.

Completed

A Study to Evaluate Ovarian Follicular Activity and Hormone Levels for DR-102 Compared to Two 28-Day Oral Contraceptives

Oral Contraceptive | Follicle Development | Ovarian Follicle | Follicle Count | Follicle Size

United States
National Institute of Allergy and Infectious Diseases...

Completed

A Study of Three Drugs Plus Zidovudine in the Prevention of Infections in HIV-Infected Patients

HIV Infections | Pneumonia, Pneumocystis Carinii

United States, Tanzania
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Efavirenz (EFV) in HIV-Infected and HIV/Tuberculosis (TB) Coinfected Children

HIV Infections | Tuberculosis

South Africa, Zimbabwe, India, Uganda
National Institute of Allergy and Infectious Diseases...

Completed

Comparing the Safety, Effectiveness, and Tolerability of Three Anti-HIV Drug Regimens for Treatment-Naive Patients

HIV Infections

United States, South Africa
Shaare Zedek Medical Center

Completed

Manipulating the Microbiome in IBD by Antibiotics and FMT (FMT)

Exacerbation of Ulcerative Colitis | Ulcerative Colitis, Active Severe | Crohn's Colitis

Israel, Italy, Canada, Finland, Poland, Spain
AbbVie

Completed

A Study to Evaluate Treatment of Hepatitis C Virus Infection in Pediatric Subjects (ZIRCON)

Chronic Hepatitis C Infection

United States, Belgium, Germany, Puerto Rico, Spain
Thomas Hope

Completed

Gallium-68 PSMA-11 PET Imaging in Prostate Cancer Patients

Prostate Cancer

United States
Clarus Therapeutics, Inc.
Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center

Completed

Pharmacokinetic Study of Oral Testosterone (T) Ester Formulations in Hypogonadal Men

Hypogonadism

United States

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