Search clinical trials for: tenecteplase

Total 89 results

Genentech, Inc.

Completed

A Study of Tenecteplase for Restoration of Function in Dysfunctional Hemodialysis (HD) Catheters (TROPICS 4)

Dysfunctional Hemodialysis Catheters
C. Michael Gibson, MS, MD
Genentech, Inc.

Completed

A Safety/Efficacy Study of Intra-coronary Tenecteplase During Balloon Angioplasty to Treat Heart Attacks (ICE T-TIMI 49)

Acute Myocardial Infarction

United States
Boehringer Ingelheim

Completed

Trial to Compare the Efficacy and Safety of a Single Bolus of TNK-tPA (Tenecteplase, Metalyse®) With Accelerated Infusion of Rt-PA (Alteplase, Actilyse®) in Asian Patients With Acute Myocardial Infarction

Myocardial Infarction

China, Korea, Republic of, Hong Kong
Boehringer Ingelheim
Genentech, Inc.

Terminated

A Trial Evaluating the Efficacy and Safety of Tenecteplase Together With Unfractionated Heparin Prior to Early Percutaneous Coronary Intervention (PCI) as Compared to Standard Primary PCI in Patients With Acute Myocardial Infarction (ASSENT 4 PCI)

Myocardial Infarction

Austria, Germany, Canada, Brazil, United States, Belgium, France, Hungary, Italy, Thailand, Greece, Czech Republic, Ireland, Mexico, Norway, Poland, Portugal, Turkey
University Hospital of North Norway
The Royal Norwegian Ministry of Health; Norwegian Health Association; UiT The...

Recruiting

Tenecteplase in Wake-up Ischaemic Stroke Trial (TWIST)

Ischemic Stroke | Stroke, Acute

Sweden, United Kingdom, Finland, Switzerland, Denmark, New Zealand, United States, Estonia, Latvia, Lithuania, Norway
University of Alberta
Eli Lilly and Company; Sanofi; Hoffmann-La Roche

Completed

Which Therapy for Acute Heart Attacks? (The WEST Study)

Myocardial Infarction

Canada
Xijing Hospital

Unknown

Intracoronary Cocktail Injection Combined With Thrombus Aspiration in STEMI Patients Treated With Primary Angioplasty

ST-elevation Myocardial Infarction

China
Beijing Tiantan Hospital
Linyi People's Hospital

Recruiting

Endovascular Treatment With or Without Preceding Intravenous Tenecteplase (TNK) in Patients With Late-window acUte Ischemic Stroke Due to Middle Cerebral Artery Occlusion (TNK-PLUS)

Thrombolysis | Ischemic Stroke, Acute | Endovascular Treatment

China
Beijing Tiantan Hospital
Fudan University; Huashan Hospital; West China Hospital; The First Affiliated Hospital... and other collaborators

Completed

Tenecteplase Reperfusion Therapy in Acute Ischemic Cerebrovascular Events(TRACE)

Acute Ischemic Stroke

China
Boehringer Ingelheim

Completed

STREAM-Strategic Reperfusion (With Tenecteplase and Antithrombotic Treatment) Early After Myocardial Infarction

Myocardial Infarction

Austria, Belgium, Brazil, Canada, Chile, France, Germany, Greece, Italy, Norway, Peru, Poland, Russian Federation, Serbia, Spain, United Kingdom
Spanish Society of Cardiology
Sanofi; Fondo de Investigacion Sanitaria; Boston Scientific Corporation; Medtronic and other collaborators

Terminated

Thrombolysis Versus Primary Angioplasty for AMI in Elderly Patients (TRIANA)

Acute Myocardial Infarction

Spain
Alexion

Completed

ALXN1210 Versus Eculizumab in Adult Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH) Currently Treated With Eculizumab

Paroxysmal Nocturnal Hemoglobinuria (PNH)

United States, Korea, Republic of, Canada, France, Germany, Spain, United Kingdom, Japan, Australia, Italy, Netherlands
University of Calgary

Completed

Alteplase Compared to Tenecteplase in Patients With Acute Ischemic Stroke (AcT)

Stroke, Acute | Thromboses, Intracranial

Canada
Haukeland University Hospital

Terminated

The Norwegian Tenecteplase Stroke Trial 2 (NOR-TEST 2)

Cerebrovascular Disorders | Ischemic Stroke | Stroke, Acute

Norway
Lars Thomassen
The Research Council of Norway

Completed

Study of Tenecteplase Versus Alteplase for Thrombolysis (Clot Dissolving) in Acute Ischemic Stroke (NOR-TEST)

Ischemic Stroke

Norway
Beijing Tiantan Hospital

Completed

Teneteplase Reperfusion Therapy in Acute Ischemic Cerebrovascular Events-III (TRACE III)

Ischemic Stroke, Acute

China
The First Affiliated Hospital of University of...

Recruiting

Intravenous Tenecteplase Plus EVT Versus EVT Alone on 4.5 to 24 Hours After Basilar Artery Occlusion

Basilar Artery Occlusion | Acute Cerebrovascular Accident | Stroke Due to Basilar Artery Occlusion

China
Reza Behrouz, DO

Withdrawn

Tenecteplase Versus Alteplase in Ischemic Stroke Management (TALISMAN) (TALISMAN)

Ischemic Stroke

United States
Xijing Hospital

Unknown

Cocktail Injection Improves Outcomes of FFR Guided PCI (CocktailII)

Acute Coronary Syndromes

China
Supergene, LLC

Unknown

Single Bolus Recombinant Nonimmunogenic Staphylokinase (FORtelyzin) Versus Single Bolus Tenecteplase (Metalyse) in STEMI (FORMAT-1)

Myocardial Infarction

Russian Federation
Boehringer Ingelheim

Completed

A Study to Investigate the Procoagulant Effect of Tenecteplase (TNK-tPA), Alteplase (Rt-PA) and Streptokinase (SK) Administered to Patients With Acute Myocardial Infarction (AMI)

Myocardial Infarction
Beijing Tiantan Hospital
Jiangsu FENG HUA Biotech Pharmaceutical Co., Ltd; The Place Pharmaceutical(Jiangsu)...

Recruiting

Thrombolysis Treated With TNK-tPA in Acute Ischemic Stroke Patients （3T Stroke-Ⅲ）

Acute Ischemic Stroke

China
Beijing Tiantan Hospital
Jiangsu FENG HUA Biotech Pharmaceutical Co., Ltd; The Place Pharmaceutical(Jiangsu)...

Active, not recruiting

Thrombolysis Treated With TNK-tPA in Acute Ischemic Stroke Patients （3T Stroke-II）

Acute Ischemic Stroke

China
Hooman Poor
Genentech, Inc.

Completed

Tenecteplase in Patients With COVID-19

COVID-19 | Respiratory Failure | ARDS

United States
Neuroscience Trials Australia
The Florey Institute of Neuroscience and Mental Health

Completed

Tenecteplase Versus Alteplase Before Endovascular Therapy for Ischemic Stroke (EXTEND-IA TNK)

Ischemic Stroke

Australia, New Zealand
University of Melbourne

Recruiting

Extending the Time Window for Tenecteplase by Recanalization of Basilar Artery Occlusion in Posterior Circulation Stroke (POST-ETERNAL)

Basilar Artery Occlusion

Australia
Huashan Hospital
Shanghai 10th People's Hospital; Shanghai Fifth People's Hospital; Shanghai Deji... and other collaborators

Recruiting

Tenecteplase Thrombolytic Therapy for Acute Ischemic Stroke in China (TTT-AIS CHINA)

Ischemic Stroke

China
University of Melbourne
Professor Mark Parsons

Recruiting

Extending the Time Window for Tenecteplase by Effective Reperfusion in Patients With Large Vessel Occlusion (ETERNAL-LVO)

Ischemic Stroke

Australia
Tomsk National Research Medical Center of the Russian...

Completed

Intramyocardial Haemorrhage in Patients With Primary STEMI (HaemInCor)

Myocardial Infarction | Myocardial Injury | STEMI | Myocardial Necrosis

Russian Federation
Melbourne Health

Completed

Tenecteplase Versus Alteplase for Stroke Thrombolysis Evaluation Trial in the Ambulance (TASTEa)

Stroke, Acute, Stroke Ischemic

Australia
Oslo University Hospital

Recruiting

TENecteplase in Central Retinal Artery Occlusion Stuy (TenCRAOS) (TenCRAOS)

Central Retinal Artery Occlusion

Denmark, Norway, Belgium, Sweden, Finland, Ireland, Lithuania, Australia, Austria
NHS Greater Glasgow and Clyde
University of Glasgow

Completed

Alteplase-Tenecteplase Trial Evaluation for Stroke Thrombolysis- (ATTEST) (ATTEST)

Stroke

United Kingdom
Beijing Tiantan Hospital

Recruiting

Tenecteplase Reperfusion Therapy in Acute Ischaemic Cerebrovascular Events-5 (TRACE-5)

Ischemic Stroke, Acute

China
Boehringer Ingelheim

Completed

Full Dose Tenecteplase (TNK-tPA) Together With Heparin Sodium, Full Dose Tenecteplase With Enoxaparin, Half Dose Tenecteplase Together With Abciximab and Heparin Sodium in Patients With Acute Myocardial Infarction (AMI) (ASSENT 3)

Myocardial Infarction
Cedars-Sinai Medical Center
Genentech, Inc.

Terminated

Low-Dose Tenecteplase in Covid-19 Diagnosed With Pulmonary Embolism

COVID | Pulmonary Embolism

United States
KU Leuven
Boehringer Ingelheim; Life Sciences Research Partners; Fund for Clinical Cardiovascular...

Active, not recruiting

STrategic Reperfusion in Elderly Patients Early After Myocardial Infarction (STREAM-2)

Myocardial Infarction

Canada, France, Mexico, Australia, Brazil, Chile, Montenegro, Russian Federation, Serbia, Spain
University of Calgary

Active, not recruiting

A Randomized Controlled Trial of TNK-tPA Versus Standard of Care for Minor Ischemic Stroke With Proven Occlusion (TEMPO-2)

Stroke, Acute

United Kingdom, Australia, Canada, Singapore, New Zealand, Brazil, Ireland, Spain, Austria, Finland
Huashan Hospital
Shanghai 10th People's Hospital; Shanghai East Hospital; Zhejiang University; The... and other collaborators

Completed

CHinese Acute Tissue-Based Imaging Selection for Lysis In Stroke -Tenecteplase II (CHABLIS-T II)

Stroke

China
University of British Columbia
Post Graduate Institute of Medical Education and Research, Chandigarh

Unknown

Non-invasive Ventilation vs. Standard Therapy for Children Hospitalized With an Acute Exacerbation of Asthma

Asthma in Children | Asthma Acute

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