Latest Trials

Total 2673 results

UCB Pharma
Biogen

Completed

Safety Study of CDP7657 in Patients With Systemic Lupus Erythematosus

Immune System Diseases | Autoimmune Diseases | Lupus Erythematosus, Systemic | Skin and Connective Tissue Diseases | Connective Tissue Disease

Bulgaria, Belgium, Germany, Poland, Romania, Russian Federation, Spain
AstraZeneca

Completed

Study to Assess the Efficacy and Safety of AZD1981 in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD) (Columbus)

Moderate to Severe COPD

Sweden, Bulgaria, Poland, Denmark, Slovakia
Regeneron Pharmaceuticals

Active, not recruiting

A Trial to Learn How Well REGN9933 Works for Preventing Blood Clots After Knee Replacement Surgery in Adult Participants

Venous Thromboembolism

Poland, Latvia, Canada, Belgium, Bulgaria, Hungary, Lithuania
Prestige Biopharma Limited

Completed

A Phase III Trial to Compare the Efficacy, Safety and Pharmacokinetics of HD201 to Herceptin® in HER2+ Early Breast Cancer Patients (TROIKA)

HER2 Positive Breast Cancer

Spain, Malaysia, Estonia, Hungary, Thailand, Belarus, Bulgaria, France, Georgia, Italy, Poland, Russian Federation, Ukraine
Amgen

Terminated

Safety and Efficacy of Efavaleukin Alfa in Subjects With Active Rheumatoid Arthritis

Rheumatoid Arthritis RA

United States, Poland, Germany, Bulgaria, Spain
Baxalta now part of Shire

Completed

IMMUNINE Pre-Treatment Study

Hemophilia B

Colombia, Bulgaria, Chile, Poland, Romania, Argentina, Brazil, Czechia, Russian Federation, Ukraine
Vir Biotechnology, Inc.

Recruiting

SOLSTICE: Combination Therapy for the Treatment of Chronic Hepatitis D Infection.

Hepatitis D, Chronic

New Zealand, United Kingdom, Moldova, Republic of, Romania, Bulgaria, Italy, Germany, France, Netherlands
Pharming Technologies B.V.

Recruiting

C1 Inhibitor Registry in the Treatment of Hereditary Angioedema (HAE) Attacks

Hereditary Angioedema

Germany, Bulgaria, Croatia, Czechia, France, Hungary, Italy, North Macedonia, Poland, Slovakia, Norway, Slovenia, Sweden
Tricida, Inc.

Completed

Long-term Safety Extension to Study TRCA-301

Metabolic Acidosis

United States, Bulgaria, Georgia, Hungary, Serbia, Slovenia, Ukraine
argenx

Recruiting

A Study to Assess the Long-term Safety and Efficacy of a Subcutaneous Formulation of Efgartigimod in Adults With Active Idiopathic Inflammatory Myopathy (ALKIVIA+)

Myositis | Dermatomyositis | Polymyositis | Antisynthetase Syndrome | Immune-Mediated Necrotizing Myopathy | Active Idiopathic Inflammatory Myopathy

Korea, Republic of, United States, Bulgaria, Belgium, Denmark, Georgia, Greece, Lithuania, Argentina
Institut d'Investigació Biomèdica de Bellvitge
UMC Utrecht; Tel Aviv University; University of Bristol; AiCuris Anti-infective...

Completed

Study to Assess Management and Outcomes of Hospitalised Patients With Complicated UTI (RESCUING) (RESCUING)

Urinary Tract Infections | Bacterial Resistance

Israel, Spain, Greece, Italy, Bulgaria, Hungary, Romania, Turkey
Laguna Pharmaceuticals, Inc.

Terminated

Safety and Efficacy of Vanoxerine for the Conversion of Subjects With Recent Onset Atrial Fibrillation or Flutter to Normal Sinus Rhythm (RESTORE SR)

Atrial Fibrillation or Flutter

United States, Bulgaria, Russian Federation, Hungary, Israel
Hoffmann-La Roche

Completed

A Study in Healthy Volunteers and in Participants With Chronic Hepatitis B to Assess Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single and Multiple Doses of RO7020531

Hepatitis B, Chronic

Thailand, Taiwan, United Kingdom, Hong Kong, Netherlands, New Zealand, Bulgaria, Italy
Mylan Inc.
Mylan GmbH

Completed

MYL-1401A Efficacy and Safety Comparability Study to Humira®

Psoriasis | Arthritis, Psoriatic

Bulgaria, Estonia, Hungary, Poland, Russian Federation, Ukraine
Can-Fite BioPharma

Completed

Oral CF101 Tablets and Methotrexate Treatment in Rheumatoid Arthritis Patients

Rheumatoid Arthritis

Israel, Czechia, Bulgaria, Poland, Serbia, Ukraine
University Hospital, Geneva
Swiss National Science Foundation

Not yet recruiting

Atrial Fibrillation Ablation Versus Atrioventricular Nodal Ablation With Conduction System Pacing in Heart Failure (ABACUS)

Heart Failure | Atrial Fibrillation, Persistent

Hungary, Spain, France, Netherlands, Switzerland, Germany, Belgium, United Kingdom, Austria, Bulgaria, Czechia, Finland, Italy, Poland
Novartis Pharmaceuticals

Completed

A DDI Study to Assess the Effect of INC280 on the PK of Midazolam and Caffeine in Patients With cMET-dysregulated Advanced Solid Tumors

cMET-dysregulated Advanced Solid Tumors

United States, Spain, Italy, Bulgaria, United Kingdom, France, Denmark
Ultragenyx Pharmaceutical Inc

Completed

Phase 3 Randomized, Double-Blind, Placebo-Controlled Study to Evaluate Sialic Acid in Patients With Glucosamine (UDP-N-acetyl)-2-epimerase Myopathy (GNEM) or Hereditary Inclusion Body Myopathy (HIBM) (GNEM)

Hereditary Inclusion Body Myopathy | GNE Myopathy | Distal Myopathy With Rimmed Vacuoles | Distal Myopathy, Nonaka Type

United States, Canada, United Kingdom, Israel, Italy, Bulgaria, France
Octapharma

Completed

Wilate in Subjects With Von Willebrand Disease Who Undergo Surgery (WONDERS)

Prevent Bleeding in Major Surgery

United States, Turkey, Romania, India, Bulgaria, Italy, Oman, Poland, South Africa
AstraZeneca

Completed

Characterisation of Patients With Severe Asthma in Primary and Secondary Care Settings in Europe Reported to be Eligible for Biological Therapy (RECOGNISE)

Severe Asthma

Hungary, Germany, Bulgaria, Czechia, France, Greece, Italy, Netherlands, Poland, Romania, Slovenia, Spain
ECRI bv
Sahajanand Medical Technologies Pvt. Ltd.

Completed

Thin Strut Sirolimus-eluting Stent in All Comers Population vs Everolimus-eluting Stent (TALENT)

Coronary Stenosis

Bulgaria, Hungary, Italy, Netherlands, Poland, Spain, United Kingdom
Pharvaris Netherlands B.V.

Recruiting

Extension Study of Oral PHA-022121 for Acute Treatment of Angioedema Attacks in Patients With Hereditary Angioedema (RAPIDe-2)

Hereditary Angioedema | Hereditary Angioedema Type I | Hereditary Angioedema Type II | Hereditary Angioedema Types I and II | Hereditary Angioedema Attack | Hereditary Angioedema With C1 Esterase Inhibitor Deficiency | Hereditary Angioedema - Type 1 | Hereditary Angioedema - Type 2 | C1 Esterase Inhibitor... and other conditions

United States, Bulgaria, Czechia, Hungary, Spain, France, Germany, Poland, Canada, Israel
RVL Pharmaceuticals, Inc.
Osmotica Pharmaceutical US LLC

Completed

A Study to Investigate the Safety and Effectiveness of Arbaclofen Extended-Release Tablets for Patients With MS (OS440-3004)

Multiple Sclerosis | Spasticity, Muscle

Serbia, Belarus, Bosnia and Herzegovina, Bulgaria, Croatia, Moldova, Republic of, Poland
Boehringer Ingelheim

Recruiting

INCHANGE - Nintedanib for Changes in Cough and Dyspnea in Patients Suffering From Chronic Fibrosing Interstitial Lung Disease With a Progressive Phenotype in Everyday Clinical Practice: a Real-world Evaluation

Lung Diseases, Interstitial

Czechia, Switzerland, Romania, Bulgaria, Poland
Sandoz

Completed

Prospective, Randomized, Multinational, Multicenter, Double-blind, Placebo and Active Controlled Trial in 4 Parallel-groups of Patients Suffering From Seasonal Allergic Rhinitis

Seasonal Allergic Rhinitis

Bulgaria, Germany, Poland, Moldova, Republic of
G1 Therapeutics, Inc.

Completed

G1T48, an Oral SERD, Alone and in Combination With Palbociclib in ER-Positive, HER2-Negative Advanced Breast Cancer

Breast Cancer | Advanced Breast Cancer | Breast Neoplasm | Metastatic Breast Cancer | Stage IV Breast Cancer | Carcinoma, Ductal, Breast | Breast Cancer Female

United States, Belgium, Bulgaria, Georgia, Netherlands, Moldova, Republic of, Ukraine
Sanofi

Completed

Dose Ranging Study in Elective Total Hip Replacement Surgery (DRIVE)

Venous Thromboembolism

Argentina, Chile, Sweden, Czech Republic, Poland, Finland, Colombia, Mexico, Norway, Bulgaria, Denmark, Romania, Russian Federation, Turkey
Tris Pharma, Inc.

Completed

CORAL XT - Open-label Extension Trial of the CORAL Trial (CORAL XT)

Neoplasms | Pain | Chronic Pain

Austria, Belgium, Bulgaria, Denmark, Germany, Hungary, Poland, Romania, Serbia, Slovakia
Novartis Pharmaceuticals

Completed

Everolimus as Second-line Therapy in Metastatic Renal Cell Carcinoma (RECORD-4)

Metastatic Renal Cell Carcinoma

China, Argentina, Brazil, Russian Federation, Bulgaria, United States
Sanofi

Active, not recruiting

Tusamitamab Ravtansine (SAR408701) in Combination With Ramucirumab or Ramucirumab and Pembrolizumab in Pretreated Patients With NSQ NSCLC (CARMEN-LC04) (CARMEN-LC04)

Non-small Cell Lung Cancer Metastatic

Korea, Republic of, United States, Bulgaria, Czechia, Portugal, Spain
Cellaion SA

Enrolling by invitation

HepaStem Long-Term Safety Registry (PROLONGSTEM)

Urea Cycle Disorder | Crigler-Najjar Syndrome | Acute on Chronic Liver Failure

Belgium, Spain, France, Bulgaria, Poland
Assembly Biosciences
Arbutus Biopharma Corporation

Terminated

A Study Evaluating Treatment Regimens Containing Vebicorvir (ABI-H0731) in Participants With Chronic Hepatitis B Infection

Chronic Hepatitis B

Australia, Canada, Bulgaria, New Zealand
Hoffmann-La Roche

Recruiting

A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7565020 in Healthy Participants and in Participants With Chronic Hepatitis B Virus Infection

Chronic Hepatitis B

Korea, Republic of, United States, Thailand, Hong Kong, Spain, New Zealand, Bulgaria, Taiwan, France
Hoffmann-La Roche

Completed

A Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single and Multiple Doses of RO7049389 in Healthy Volunteers and Chronic Hepatitis B Virus (HBV) Infected Participants

Hepatitis B, Chronic

Australia, New Zealand, Singapore, Thailand, Taiwan, China, Bulgaria, Hong Kong
Actelion

Recruiting

A Study Providing Treatment Access in Participants With Pulmonary Hypertension Completing a Parent Study and Having no Other Option (PLATYPUS)

Hypertension, Pulmonary

Korea, Republic of, Taiwan, Poland, Bulgaria, Ukraine, Belgium, South Africa, Belarus, Russian Federation
Insmed Incorporated

Completed

Safety and Tolerability Study of 2 Dose Level of Arikayce™ in Patients With Bronchiectasis and Chronic Infection Due to Pseudomonas Aeruginosa.

Bronchiectasis

United States, United Kingdom, Bulgaria, India, Serbia, Ukraine, Greece, Hungary, Poland
Gilead Sciences

Completed

Safety, Tolerability, and Efficacy of GS-9876 in Participants With Active Rheumatoid Arthritis on Background Therapy With Methotrexate

Rheumatoid Arthritis

United States, Czechia, Bulgaria, Poland, Georgia, Moldova, Republic of, Ukraine
Pfizer

Completed

Study To Compare On-Demand Treatment To A Prophylaxis Regimen Of BeneFIX In Subjects With Moderately Severe to Severe Hemophilia B

Hemophilia B

Canada, Singapore, Turkey, Croatia, Korea, Republic of, Mexico, Poland, Bulgaria, Malaysia
H. Lundbeck A/S

Terminated

Efficacy of Bifeprunox in Patients With Schizophrenia

Schizophrenia

Bulgaria, China, Greece, Romania, Russian Federation, Taiwan, Thailand, Ukraine
Merz Therapeutics GmbH

Recruiting

A Clinical Trial to Investigate Efficacy and Safety of NT 201 Injections Compared With Placebo Injections in Participants Aged 18 Years and Older With Chronic Nerve Pain After Shingles or Nerve Injury (PaiNT)

Moderate to Severe Chronic Peripheral Neuropathic Pain (PNP) Due to Postherpetic Neuralgia (PHN) or Peripheral Nerve Injury

Bulgaria, Germany, Poland, France, Hungary, Spain
Ultragenyx Pharmaceutical Inc

Terminated

Study to Evaluate the Safety and Efficacy of Aceneuramic Acid Extended-Release (Ace-ER) Tablets in Patients With Glucosamine (UDP-N-acetyl)-2-epimerase Myopathy (GNEM) or Hereditary Inclusion Body Myopathy (HIBM)

Hereditary Inclusion Body Myopathy | GNE Myopathy | Distal Myopathy With Rimmed Vacuoles | Distal Myopathy, Nonaka Type | Quadriceps Sparing Myopathy

United States, Canada, United Kingdom, Israel, Italy, Bulgaria, France
Igenomix

Completed

The ERA Test as a Diagnostic Guide for Personalized Embryo Transfer (ERA RCT)

Endometrial Receptivity

Spain, Belgium, Brazil, Bulgaria, Japan, Panama, Turkey
Celyad Oncology SA

Completed

Safety and Efficacy of Autologous Cardiopoietic Cells for Treatment of Ischemic Heart Failure. (CHART-1)

Heart Failure

Spain, Israel, Belgium, Switzerland, Italy, Bulgaria, Hungary, Poland, Serbia
AstraZeneca

Active, not recruiting

Study of Durvalumab in Combination With Platinum and Etoposide for the First Line Treatment of Patients With Extensive-stage Small Cell Lung Cancer (LUMINANCE)

Extensive-stage Small Cell Lung Cancer

Canada, Germany, Italy, Czechia, Turkey, Bulgaria
Grünenthal GmbH

Completed

A Study to Look at Tapentadol Tablets in Children and Adolescents in Pain

Pain

Belgium, Bulgaria, Chile, France, Germany, Hungary, Italy, Portugal, Spain, United Kingdom
Galapagos NV

Completed

A Study to Assess Efficacy and Safety of Filgotinib in Ankylosing Spondylitis (TORTUGA)

Ankylosing Spondylitis

Belgium, Bulgaria, Czechia, Estonia, Poland, Spain, Ukraine
Amgen

Completed

Study of Haemodialysis Patients Switching From Aranesp to Biosimilar (SHADE)

Anaemia

Australia, Italy, Poland, Germany, Greece, Bulgaria, Spain
S.L.A. Pharma AG

Completed

Diltiazem Hydrochloride Cream for Anal Fissure

Chronic Anal Fissure

United Kingdom, Spain, Bulgaria, Germany, Lithuania, Romania
Innovacell AG

Recruiting

Skeletal Muscle-derived Cell Implantation for Treatment of Fecal Incontinence (Fidelia)

Fecal Incontinence

Japan, France, Sweden, Bulgaria, Spain, Austria, United Kingdom, Germany, Czechia, Italy
Berlin Heals GmbH

Recruiting

Performance and Safety of the Cardiac Microcurrent Therapy System (C-MIC-II)

Systolic Left Ventricular Dysfunction

Switzerland, Croatia, Germany, Spain, Serbia, Bosnia and Herzegovina, Bulgaria, Greece, North Macedonia, Poland, Czechia

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