Latest Trials

Total 21349 results

University of Witwatersrand, South Africa

Completed

Effect of HIV and/or Active Tuberculosis on the Immune Responses to Trivalent Influenza Vaccine (TIV) in Adults (TIV_HIV_TB)

HIV | Tuberculosis | Influenza

South Africa
GlaxoSmithKline

Completed

Primary and Booster Vaccination Study With a Pneumococcal Vaccine in HIV Infected, HIV Exposed Uninfected and HIV Uninfected Children 6 to 10 Weeks of Age.

Infections, Streptococcal

South Africa
Willem Daniel Francois Venter
Medical Research Council, South Africa

Completed

Evaluation of Low-dose Darunavir in a Switch Study (DRV)

HIV Infections

South Africa
Vanderbilt University Medical Center
University of Cape Town

Completed

CareConekta: A Pilot Study of a Smartphone App in South Africa

HIV/AIDS

South Africa
University of North Carolina, Chapel Hill
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Innovations in HIV Testing (TI)

Human Immunodeficiency Virus

South Africa
Zimmer Biomet
University of Cape Town

Completed

Sternal Closure With SternaLock 360: First in Man Study (SL360)

Sternal Fracture

South Africa
Boston University
Vanderbilt University; University of Witwatersrand, South Africa

Completed

A Pilot Voucher Incentive for Improving Retention in Postpartum HIV Care in South Africa

HIV

South Africa
University of KwaZulu
South African Society of Anaesthesiologists (SASA); Safe Surgery South Africa...

Completed

South African Paediatric Surgical Outcomes Study (SAPSOS) (SAPSOS)

Postoperative Complications | Surgery | Anesthesia | Pediatrics | Child Mortality | Hospital Mortality

South Africa
Jeffrey Kotzen
National Research Foundation of South Africa; NTP Radioisotopes SOC Ltd

Unknown

Modulated Electro-Hyperthermia Plus Chemo-radiation for Locally Advanced Cervical Cancer Patients in South Africa (mEHT)

Cervical Cancer

South Africa
Helen Joseph Hospital
University of Johannesburg; Abbott Point of Care; Lodox Systems (Ltd)

Completed

Early Point-Of-Care Blood Tests, ECG & X-rays in the Emergency Department (EPOC-BEX-ED)

Emergency Medicine | Point-of-Care Testing

South Africa
Global Alliance for TB Drug Development

Completed

Evaluation of Early Bactericidal Activity in Pulmonary Tuberculosis With(J-M-Pa-Z) (NC-001)

Pulmonary Tuberculosis

South Africa
Global Alliance for TB Drug Development

Completed

Evaluation of Early Bactericidal Activity in Pulmonary Tuberculosis With Clofazimine (C)-TMC207 (J)-PA-824 (Pa)-Pyrazinamide (Z) (NC-003)

Pulmonary Tuberculosis

South Africa
Medical Research Council, South Africa
University of Wisconsin, Madison; International Atomic Energy Agency

Completed

Total Body Vitamin A Before and After Vitamin A Supplementation in a Community Where Liver is Frequently Eaten

Hypervitaminosis A

South Africa
Chris Hani Baragwanath Academic Hospital
Masimo Corporation

Completed

Usefulness of Non-invasive Pulse Co-oximetry Haemaglobin Measurements in Critically Ill Black Patients

Critically Ill Black Patients

South Africa
University of Johannesburg

Completed

An Observational Study on the Efficacy of Individualised Homoeopathic Treatment on Premenstrual Syndrome

Premenstrual Syndrome

South Africa
University of Johannesburg

Completed

The Efficacy of Individualised Homeopathic Treatment on Constipation

Constipation

South Africa
University of Johannesburg

Completed

The Effect of Individualised Homeopathic Treatment on Low Sexual Desire in Perimenopause

Hypoactive Sexual Desire Disorder

South Africa
University of Johannesburg

Completed

The Effect of Picricum Acidum and Phosphoricum Acidum Homaccord on Perceived Levels of Anxiety in University Students

Anxiety

South Africa
University of Johannesburg

Completed

The Efficacy of OrasaltsTM in the Treatment of Gingivitis

Gingivitis

South Africa
Barbara Ensoli, MD
Italian Ministry of Foreign Affairs - General Direction for Cooperation and...

Completed

A Phase Il of a Therapeutic, Recombinant, Biologically Active HIV-1 Tat Protein Vaccine in HIV-Infected, Anti-Tat Negative, ARV-Treated Adult Volunteers (ISS T-003)

HIV Infections

South Africa
University of North Carolina, Chapel Hill
University of California, San Francisco; University of Witwatersrand, South...

Completed

Effect of Community Social Mobilization for the Prevention of HIV in Young South African Women

Gender Relations

South Africa
Mark Hatherill
Medical Research Council; University of Oxford; Wellcome Trust; Department for... and other collaborators

Completed

Safety and Immunogenicity of MVA85A Prime and Bacille Calmette-Guerin Boost Vaccination (MVA(TB)029)

HIV | Tuberculosis

South Africa
Bayer

Completed

FREEDOM - First Real-Life Evaluation of Enablex Done in ZA Overactive Bladder Patients During a 3 Months Period (FREEDOM)

Overactive Bladder

South Africa
University of Cape Town

Withdrawn

Impact of Medical Follow-up Discharge Package (RECALL-CT)

Follow-up Study | Medical In-patients

South Africa
Convergence Pharmaceuticals

Completed

Efficacy and Safety of CNV2197944 Versus Placebo in Patients With Post-herpetic Neuralgia

Post-herpetic Neuralgia

South Africa
University of Limpopo

Unknown

Effect of Vitamin D Supplementation on the Control of Asthma in Children at a South African Academic Hospital

Persistent Asthma

South Africa
National Cancer Institute (NCI)

Unknown

Combination Chemotherapy in Patients With Advanced or Recurrent Mycosis Fungoides

Lymphoma

South Africa
Nestlé

Terminated

Necrotizing Enterocolitis (Nec) and B. Lactis in Premature Babies

Necrotizing Enterocolitis

South Africa
Vakzine Projekt Management GmbH
University of Stellenbosch; Children's Infectious Diseases Clinical Research... and other collaborators

Completed

Study to Evaluate Safety and Immunogenicity of VPM1002 in Comparison With BCG in Newborn Infants in South Africa

Tuberculosis

South Africa
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Voluntary HIV Counseling, Testing, and Medication for Pregnant Women to Prevent Mother-to-Child HIV Transmission

HIV Infections

South Africa
University of Witwatersrand, South Africa

Terminated

Differences Between Stavudine and Tenofovir Each Combined With Lamivudine and Efavirenz in SA HIV-infected Patients (CHRU01)

Metabolic Complications | Mitochondrial Toxicity

South Africa
University of Cape Town
VU University of Amsterdam

Unknown

Working on Wellness (WOW) Intervention (WOW)

Physical Activity

South Africa
Neurotune AG
Cross Research S.A.; Triclinium clinical trial project managment LTD

Completed

Safety and Preliminary Evidence of Efficacy of Escalating Doses of Dimiracetam in AIDS Patients With Painful Neuropathy

Neuropathy | AIDS

South Africa
University of Witwatersrand, South Africa

Completed

Exercise for Low Back Pain in Children (LBP)

Low Back Pain

South Africa
University of Oxford
University of Cape Town

Completed

Safety and Immunogenicity of MVA85A, in Healthy Volunteers in Cape Town

Tuberculosis

South Africa
Wits RHI Research Centre Clinical Research Site
University of Alabama at Birmingham; University of California, San Francisco

Recruiting

PrEP Restart for Adolescent Girls and Young Women Using STI Self Testing and Assessment of Risk (PALESA)

HIV Prevention

South Africa
University of Cape Town
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

B. Infantis Supplementation to Improve Immunity in Infants Exposed to HIV (BifIID)

Vaccine Reaction | Hiv | Microbial Colonization | Infant Development

South Africa
Cryonove Pharma
CEISO; Dermatech; Sefako Makgatho Health Sciences University

Not yet recruiting

Tolerance and Performance of Cyto-selective Difluoroethane-based Cryotherapy in the Treatment of Brown Spots (Solar and Senile Lentigines, Post-Inflammatory Hyperpigmentation)

Solar Lentigo | Post Inflammatory Hyperpigmentation | Senile Lentigo

South Africa
University of Witwatersrand, South Africa
Massachusetts General Hospital; Emory University; UMC Utrecht

Recruiting

iHEART-SA Intervention Study (iHEART-SA)

Hypertension | HIV

South Africa
RTI International
Medical Research Council, South Africa

Recruiting

Adapting and Testing a Behavioural Intervention to Prevent FASD and Adverse Infant Outcomes (MaRISA+)

Alcohol Drinking | Maternal Behavior | Fetal Conditions

South Africa
Istituto Superiore di Sanità

Recruiting

Extended Follow-Up of the ISS T-003 Trial Volunteers (ISS T-003 EF-UP2020) (T003EFUP2020)

HIV Infections

South Africa
University of California, San Francisco
National Institute of Mental Health (NIMH); University of Witwatersrand, South...

Recruiting

Friendship Bench Mental Health Intervention for Adolescent Girls and Young Women in South African PrEP Delivery Settings

Depression | Pre-Exposure Prophylaxis

South Africa
University of California, San Francisco
National Institute of Allergy and Infectious Diseases (NIAID); University Hospital... and other collaborators

Not yet recruiting

Pragmatic Use of Next-generation Sequencing for Management of Drug-resistant Tuberculosis (TSELiOT)

Drug-resistant Tuberculosis | Cost-Benefit Analysis | HIV Coinfection

South Africa
GlaxoSmithKline
Click-TB Consortium

Recruiting

Early Bactericidal Activity, Safety & Tolerability of Oral GSK3036656 in a Dual Combination With Novel and Established Antitubercular Agents, or Standard of Care in Adults With Rifampicin Susceptible Pulmonary Tuberculosis

Tuberculosis

South Africa
University of California, Los Angeles
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

Stepped Care to Optimize PrEP Effectiveness in Pregnant and Postpartum Women (SCOPE-PP)

Hiv

South Africa
Swiss Federal Institute of Technology
University of Stellenbosch

Recruiting

Potential of Prebiotic Galacto-oligosaccharides in Improving Efficacy and Safety of Oral Iron Supplementation in HIV-infected Children

HIV | Iron Deficiency

South Africa
Duke University
The Emmes Company, LLC

Recruiting

Pharmacokinetics of Antiretroviral Drugs in Lactating Women and Breastmilk Fed Infants Under 6 Months of Age in Botswana (BMS02)

HIV Infections | Lactating Women on Select DOI | Breastmilk Fed Infants of Mothers on Select DOI

South Africa
University of Cape Town
University of Zurich; University of Bern; University of Stellenbosch; University...

Recruiting

Atorvastatin to Reduce Inflammation After Tuberculosis Treatment Completion (StatinTB)

Tuberculosis, Pulmonary

South Africa
University of Pretoria
University of Stellenbosch

Recruiting

Screening Study for Cervical Pre-cancer and Cancer Prevention in South African Women. (DiaVACCS)

Cervical Cancer | CIN2 | High Grade Sil

South Africa
UNC Lineberger Comprehensive Cancer Center
Fogarty International Center of the National Institute of Health

Completed

Finding Barriers and Designing Solutions to Promote Women s Cancer Screening in South Africa (FIND)

Cervical Cancer

South Africa

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