Clinical Trials Sponsored by ON Light Sciences

Total 356 results

ON Light Sciences

Completed

Evaluation of the Safety and Efficacy of the DeScribe™ Patch

Tattoos

United States
Light Sciences Oncology

Completed

Tumor Ablation With Talaporfin Sodium and Interstitial Light Emitting Diodes Treating Hepatocellular Carcinoma (HCC)

Carcinoma, Hepatocellular | Liver Neoplasms

Taiwan, Hong Kong, Singapore
Light Sciences Oncology

Completed

A Phase 3 Study of Talaporfin Sodium and Interstitial Light Emitting Diodes Treating Hepatocellular Carcinoma (HCC)

Carcinoma, Hepatocellular | Liver Neoplasms

Philippines, Korea, Republic of, Singapore, Sweden, Malaysia, India, Serbia, Thailand, Croatia, Hong Kong, Poland
Light Sciences LLC

Completed

Study to Evaluate the Safety and Efficacy of a Low Level Light Device in Patients With Knee Osteoarthritis

Osteoarthritis, Knee

United States
Light Sciences LLC

Completed

Photodynamic Therapy System for Patients With Refractory/Unresponsive Solid Tumors

Sarcoma | Breast Cancer | Head and Neck Cancer | Colorectal Cancer | Rectal Cancer | Pelvic Cancer | Mouth Cancer | Liver Metastasis

United States
Light Sciences Oncology

Completed

Phase 3 Trial of Litx™ Plus Chemotherapy vs. Chemotherapy Only Treating Colorectal Cancer Patients With Recurrent Liver Metastases

Neoplasm Metastasis | Colorectal Neoplasms | Liver Metastases | Neoplasm Recurrence, Local

Sweden, India, Austria, Serbia, Germany, Romania, Croatia, Bosnia and Herzegovina, Italy, Latvia, Poland, Russian Federation, Ukraine
Light Sciences Oncology

Completed

Phase IIa Safety and Light Dose-escalation Study in Patients With Primary or Recurrent/High-grade Glioma Using the Litx™ System to Confirm the Zone of Tumor Destruction During the Intraoperative Treatment of Glioma

Glioma | Glioblastoma Multiforme | Anaplastic Astrocytoma

Serbia
Light Sciences LLC

Terminated

Study of Talaporfin Sodium Photodynamic Therapy to Treat Advanced Age Related Macular Disease

Macular Degeneration | Choroidal Neovascularization

United States
Light Sciences Oncology

Completed

Phase 1 Study of the Litx™ BPH System in Patients With Lower Urinary Tract Symptoms (LUTS) Due to Benign Prostatic Hyperplasia (BPH)

Lower Urinary Tract Symptoms | Benign Prostatic Hyperplasia

United States
Light Sciences Oncology

Completed

Study of Light-Activated Talaporfin Sodium in Patients With Lower Urinary Tract Symptoms (LUTS) Due to Benign Prostatic Hyperplasia (BPH)

Lower Urinary Tract Symptoms | Benign Prostatic Hyperplasia

New Zealand, Australia
Light Sciences LLC

Completed

Study of the Litx™ System Combined With Chemotherapy in Patients With Colorectal Liver Metastases

Neoplasm Metastasis | Liver Neoplasms | Colorectal Neoplasms | Liver Metastasis

United States
Light Sciences LLC

Completed

Photodynamic Therapy With Talaporfin Sodium (LS11) in Treating Patients With Refractory Colorectal Liver Metastases

Neoplasm Metastasis | Liver Neoplasms | Colorectal Neoplasms | Liver Metastasis

United States, Germany
Sight Sciences, Inc.

Completed

A Clinical Study To Assess The Safety And Effectiveness Of The OMNI® Surgical System

Glaucoma, Open-Angle

United States
Sight Sciences, Inc.

Completed

An Observational Multicenter Clinical Study To Assess The Safety And Effectiveness Of The OMNI® Surgical System In Pseudophakic Eyes With Primary Open Angle Glaucoma (ORION 2.0)

Glaucoma, Open-Angle

United States
Sight Sciences, Inc.

Terminated

A Post-market Study Of Use Of The OMNI® Surgical System In Open Angle Glaucoma

Glaucoma, Open-Angle

United States
Sight Sciences, Inc.

Unknown

TearCare System to Treat Dry Eye Disease (OLYMPIA)

Dry Eye | Meibomian Gland Dysfunction

United States
Sight Sciences, Inc.

Unknown

Study of the TearCare System in Dry Eye Disease

Dry Eye

United States
Sight Sciences, Inc.

Unknown

Pilot Study of the TearCare System

Dry Eye

United States
Sight Sciences, Inc.

Not yet recruiting

A Clinical Trial Comparing the OMNI Surgical System to Standard Medical Treatment in Pseudophakic Eyes (EVOLVE)

Primary Open Angle Glaucoma

United States
Sight Sciences, Inc.

Active, not recruiting

Prospective, Randomized, Masked, Controlled Trial To Evaluate The Safety And Effectiveness Of The TearCare® System In The Treatment Of The Signs And Symptoms Of Dry Eye Disease (SAHARA)

Dry Eye | Meibomian Gland Dysfunction

United States
Sight Sciences, Inc.

Terminated

Study of OMNI Surgical System and iStent for Eyes With OAG (Trident)

Glaucoma, Open-Angle

Germany, Spain, United Kingdom
Sight Sciences, Inc.

Terminated

Randomized Study of the Safety and Effectiveness of the TearCare System for the Signs and Symptoms of Dry Eye Disease

Dry Eye Syndromes

United States
Sight Sciences, Inc.

Unknown

Use of the OMNI® Surgical System in Combination With Cataract Extraction in Open Angle Glaucoma

Open Angle Glaucoma

United States
Sight Sciences, Inc.

Terminated

Randomized Study of the Safety and Effectiveness of the Sight Sciences VISCO™360 Viscosurgical System Versus SLT in Primary Open Angle Glaucoma (VISCO360 Study)

Open-Angle Glaucoma

United States
Sight Sciences, Inc.

Terminated

A Prospective, Multicenter Study of the OMNI® Surgical System in Pseudophakic Eyes With Open Angle Glaucoma (ORION)

Glaucoma, Open-Angle

United States
Sight Sciences, Inc.

Unknown

Pilot Study of TearCare System - Long-Term Extension

Dry Eye Syndromes

United States
Light Sciences Oncology
Mundipharma Research Limited

Completed

A Placebo Controlled Study of MR901 (Talaporfin Sodium Sodium + a Drug-activating Device) for the Relief of Lower Urinary Tract Symptoms Due to Benign Prostatic Hyperplasia

Benign Prostatic Hyperplasia

United States
Philadelphia Fight
Gilead Sciences

Completed

Validation of a Urine Assay to Measure Tenofovir Levels in Patients Taking Tenofovir Alafenamide

Hiv

United States
Tangible Science
Boston Sight

Unknown

Evaluation of Tangible Boost for Patients With Stevens Johnson Syndrome, Sjogren's Syndrome, and Graft Vs Host Disease

Dry Eye | Stevens-Johnson Syndrome | Sjogren's Syndrome | Graft Versus Host Disease in Eye

United States
Association for Innovation and Biomedical Research...

Recruiting

Characterization of Potential Biomarkers of Eye Disease and Vision (EYE-MARKER)

Eye Disease

Portugal
Association for Innovation and Biomedical Research...

Completed

Biomarkers of Diabetic Retinopathy Progression (C-Tracer)

Type 2 Diabetes Mellitus | Mild Nonproliferative Diabetic Retinopathy

Portugal, India
Association for Innovation and Biomedical Research...

Completed

Retinal Thickness Analysis Using Optical Coherence Tomography

Diabetic Retinopathy

Portugal
Association for Innovation and Biomedical Research...

Active, not recruiting

Prediction of Progression of Retinal Ischemia in Diabetes (PREDICTION)

Diabetic Retinopathy

Portugal
Association for Innovation and Biomedical Research...

Completed

Progression of Diabetic Retinopathy. Identification of Signs and Surrogate Outcomes (PROGRESS)

Diabetic Retinopathy

Portugal
Association for Innovation and Biomedical Research...

Completed

Five-year Incidence of Age-related Macular Degeneration in the Central Region of Portugal (AMDIncidencePT)

Age-Related Macular Degeneration

Portugal
Association for Innovation and Biomedical Research...

Completed

Characterization of Eyes With Diabetic Macular Edema That Show Different Treatment Response to Intravitreal Anti-VEGF (CHARTRES) (CHARTRES)

Diabetic Macular Edema

Portugal
Association for Innovation and Biomedical Research...

Completed

Life Style and Food Habits Questionnaire in the Portuguese Population Aged 55 or More

Age Related Macular Degeneration

Portugal
Association for Innovation and Biomedical Research...

Completed

Characterization of Early Markers of Choroidal Neovascularization (CNV-Markers)

Age-related Macular Degeneration

Portugal
Association for Innovation and Biomedical Research...

Completed

Function and Structure Imaging in Different Retinal Diseases: Retinal Leakage Analyzer Versus Optical Coherence Tomography

Age-Related Macular Degeneration | Diabetic Retinopathy | Macular Edema

Portugal
Association for Innovation and Biomedical Research...

Recruiting

Evaluation of a Health Education Program for Type 2 Diabetes Patients (EDUCA-DM)

Retinopathy, Diabetic

Portugal
Association for Innovation and Biomedical Research...

Recruiting

Diabetic Retinopathy Classification: ETDRS 7-fields vs Widefield Imaging (ClarusDR) (ClarusDR)

Retinopathy, Diabetic

Portugal
Association for Innovation and Biomedical Research...

Recruiting

Can the Risk for AMD be Modulated? (AMD_LifeGene)

Age-Related Macular Degeneration (ARMD)

Portugal
Association for Innovation and Biomedical Research...

Recruiting

10-year Progression of Diabetic Retinopathy: Identification of Signs and Surrogate Outcomes (PROGRESS10)

Diabetic Retinopathy

Portugal
Association for Innovation and Biomedical Research...

Completed

Metabolomics: A Novel Tool for Investigating the Pathogenesis of Age-related Macular Degeneration (AMDMetab)

Age-related Macular Degeneration

Portugal
Association for Innovation and Biomedical Research...

Completed

A Pilot Study on the Effect and Safety of Iluvien® in Chronic Diabetic Macular Edema Patients (RESPOND)

Diabetic Macular Edema

Portugal
Association for Innovation and Biomedical Research...

Completed

Clinical Evaluation of Noninvasive OCT Angiography Using a Zeiss OCT Prototype to Compare to Fluorescein Angiography (OCTA)

Diabetic Retinopathy

Portugal
Association for Innovation and Biomedical Research...

Completed

Epidemiological Study of the Prevalence of Age-Related Macular Degeneration in Portugal

Age-Related Macular Degeneration

Portugal
Association for Innovation and Biomedical Research...

Completed

Validation of a New Methodology for Mapping the Human Blood-Retinal Barrier Function

Diabetic Macular Edema | Age-Related Maculopathy

Portugal
Association for Innovation and Biomedical Research...

Completed

Prospective, Randomized, Open Label, Phase II Study to Assess Efficacy and Safety of Macugen® (Pegaptanib 0.3 mg Intravitreal Injections) Plus Panretinal Photocoagulation and PRP (Monotherapy) in the Treatment With High Risk PDR.

Diabetes Mellitus Type II | Diabetes Mellitus Type I | High Risk Proliferative Diabetic Retinopathy

Portugal
Association for Innovation and Biomedical Research...

Completed

Phenotyping Diabetic Retinopathy

Diabetic Retinopathy

Portugal

Clinical Trials Sponsored by ON Light Sciences

Sponsors and Collaborators

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Drug Interventions

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CROs in Suriname

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