Clinical Trials Sponsored by Osiris Therapeutics

Total 6410 results

Osiris Therapeutics

Terminated

Study to Evaluate the Safety and Efficacy of CHAM* for the Treatment of Diabetic Foot Ulcers (*OTI-15-01)

Chronic Diabetic Foot Ulcers

United States
Osiris Therapeutics

Completed

GrafixPRIME® for the Treatment of Chronic Diabetic Foot Ulcers

Foot Ulcer, Diabetic

United States
Osiris Therapeutics

Terminated

TruSkin®: Study for Treatment of Chronic Venous Leg Ulcers

Chronic Venous Leg Ulcers

United States
Osiris Therapeutics

Completed

Study to Evaluate Safety and Efficacy of GrafixPL for the Treatment of Venous Leg Ulcers

Venous Leg Ulcer

United States
Osiris Therapeutics

Completed

GrafixCORE®: Open-Label Study to Evaluate the Safety and Efficacy of GrafixCORE® for Complex Diabetic Foot Wounds

Complex Diabetic Foot Wounds

United States
Osiris Therapeutics

Completed

Grafix® DFU: Open-Label Extension Option to Evaluate Safety & Efficacy of Grafix® for Chronic Diabetic Foot Ulcers (DFU)

Diabetic Foot Ulcers

United States
Osiris Therapeutics

Terminated

TruSkin®: Study for the Treatment of Chronic Diabetic Foot Ulcers

Diabetic Foot Ulcers

United States
University of Texas Southwestern Medical Center
Osiris Therapeutics

Completed

GrafixPL PRIME Evaluation Case Study

Diabetic Foot Ulcer

United States
University of Texas Southwestern Medical Center
Osiris Therapeutics

Completed

Cryopreserved vs. Lyopreserved Stravix as an Adjunct to NPWT in the Treatment of Complex Wounds

Diabetic Wound

United States
Sirius Therapeutics Co., Ltd.

Recruiting

A Phase 1 Study to Evaluate the Safety, Tolerability, PK/PD of SRSD107 in Healthy Participants

Thrombosis

Australia
ONIRIS

Completed

Efficacy and Compliance of the Mandibular Advancement Devices ONIRIS® vs. Custom Made Devices (IRIS)

Obstructive Sleep Apnea

France
ONIRIS

Completed

Mandibular Advancement Devices Tali® in Patients With Syndrome of Obstructive Sleep Apnea and Hypopneas

Syndrome of Obstructive Sleep Apnea and Hypopneas

France
Nantes University Hospital
ONIRIS

Unknown

Prevalence and Risk Factors for Coxiella Burnetii Seropositivity (Q Fever) Among Adults in Western France (MEDVETFQ)

Q Fever

France
Nantes University Hospital
ONIRIS

Completed

Endometriosis and Brominated Flame Retardant (ENDOTOX Study) (ENDOTOX)

Endometriosis

France
University Hospital, Grenoble
ONIRIS

Terminated

Combination Therapy Associating CPAP and Mandibular Advancement Device in OSA (PPC-OAM)

Obstructive Sleep Apnea Syndrome | Hypertension

France
Sirius Genomics Inc.

Unknown

Pharmacogenomic Biomarker Study for Recombinant Human Activated Protein C Treatment in Severe Sepsis

Septic Shock | Severe Sepsis

United States, Canada, France, United Kingdom
Ranok Therapeutics (Hangzhou) Co., Ltd.

Recruiting

A Study of RNK05047 in Subjects With Advanced Solid Tumors/Diffuse Large B-cell Lymphoma (CHAMP-1)

Advanced Solid Tumor | DLBCL

United States
Hospital Sirio-Libanes

Recruiting

Effects of Electrical Stimulation for Preventing Loss of Muscle Mass in Patients With Sepsis

Sepsis | Septic Shock

Brazil
Hospital Sirio-Libanes

Completed

Assessing the Agreement Between Endoscopic and Histopathological Diagnosis of Colorectal Sessile Serrated Lesions.

Colorectal Cancer | Colonoscopy | Adenoma Detection Rate | Adenoma Colon | Colorectal Polyp | Sessile Serrated Adenoma | Quality Indicator

Brazil
Hospital Sirio-Libanes

Completed

Exploratory Study to Determine Tissue Alterations of Advanced Hepatocellular Carcinoma Induced by Electromagnetic Waves of Low Energy Amplitude Modulated to Specific Frequencies During Imaging Study by MRI

Primary or Metastatic Tumor in the Liver Parenchyma

Brazil
Hospital Sirio-Libanes

Completed

Determination of Autonomic Responses to Exposure to Electromagnetic Fields With Low Energy Modulated Frequency

Breast Cancer | Hepatocellular Carcinoma

Brazil
Hospital Sirio-Libanes

Completed

Identification of Specific Modulation Frequencies in Hepatitis B Carriers With and Without Hepatocellular Carcinoma (THBC-HSL2)

Hepatitis | Hepatocellular Carcinomas

Brazil
Hospital Sirio-Libanes

Completed

Effectiveness of Chest Physiotherapy in Infants With Acute Viral Bronchiolitis (ECPAVB)

Viral Bronchiolitis

Brazil
Hospital Sirio-Libanes

Recruiting

Pericapsular Nerve Block in Proximal Femoral Fractures

Femoral Fracture

Brazil
Hospital Sirio-Libanes

Not yet recruiting

Promotion of Sleep for Patients Submitted to Percutaneous Intervention to Treat Heart Diseases

Sleep Hygiene
Hospital Sirio-Libanes

Active, not recruiting

Pain Control in Breast Surgery: Analgesia, Opioid Consumption and Inflammatory Response Evaluation

Breast Cancer | Anesthesia

Brazil
Hospital Sirio-Libanes

Completed

Epidemiology of Respiratory Insufficiency in Critical Care (ERICC)

Acute Respiratory Failure

Brazil
Hospital Sirio-Libanes

Completed

Diaphragm Activity During Incentive Spirometry and Diaphragmatic Breathing

Breathing Exercises | Incentive Spirometry | Diaphragmatic Breathing | Diaphragm Mobility

Brazil
Asieris Pharmaceuticals (AUS) Pty Ltd.

Completed

A Phase I, Two-phase, Crossover Study to Evaluate the Safety, Tolerability and Pharmacokinetics of APL-1501 ER Tablets

Bladder Cancer

Australia
Hospital Sirio-Libanes

Recruiting

Walking Aid and Locomotion Knowledge in Emergency Rooms (WALKER 1) for Elderly People (WALKER 1)

Mobility Limitation

Brazil
Hospital Sirio-Libanes

Recruiting

Efficacy of Combined Low- and High- Frequency Stimulation in Peripheral Muscle Function During Hemodialysis

Chronic Kidney Diseases

Brazil
Hospital Sirio-Libanes

Recruiting

Determination of Autonomic Responses to the Exposure of Low Energy Electromagnetic Fields With Frequency Modulation in Patients With Advanced Hepatocellular Carcinoma and Healthy Individuals.

Hepatocellular Carcinoma

Brazil
Hospital Sirio-Libanes

Active, not recruiting

Glioma Microenvironment an Exploratory Study

Glioma of Brain

Brazil
Hospital Sirio-Libanes

Terminated

Prognostic Value Related to the Presence of Thrombosis or Portal Vein Invasion in Patients With Hepatocellular Carcinoma Submitted to Surgery (HSL2012-06)

Hepatocellular Carcinoma | Hepatic Portal Vein Tumor Invasion | Portal Vein Thrombosis

Brazil
Hospital Sirio-Libanes

Active, not recruiting

Evaluation of the Functional Results of Bilateral Amygdalotomy for Refractory Aggressive Patients

Aggression
Hospital Sirio-Libanes

Completed

Impact of Inspiratory Muscle Pressure Curves on the Ability of Professionals to Identify Patient-ventilator Asynchronies (Pmus)

Mechanical Ventilation Complication

Brazil
Hospital Sirio-Libanes

Completed

Fat Grafts With Adipose-derived Regenerative Cells for Soft Tissue Reconstruction in Children

Craniofacial Microsomia

Brazil
Hospital Sirio-Libanes

Unknown

Hypofractionated Intensity Modulated and Image Guided Radiotherapy for Localized Prostate Cancer

Prostatic Neoplasms

Brazil
Hospital Sirio-Libanes

Completed

Surgical Treatment in Diabetic Patients With Grade 1 Obesity

Obesity | Type 2 Diabetes Mellitus

Brazil
Hospital Sirio-Libanes

Completed

Exercise Tolerance in Patients With Decompensated Heart Failure

Heart Failure

Brazil
Hospital Sirio-Libanes

Completed

Epipericardial Fat Necrosis: A Misdiagnosed Condition (epipericardial)

Epipericardial Fat Necrosis

Brazil
Hospital Sirio-Libanes

Completed

Chest Compression Technique in Infants

Atelectasis

Brazil
Akebia Therapeutics
Cyclerion Therapeutics

Completed

A Study to Evaluate the Soluble Guanylate Cyclase (sGC) Stimulator IW-1973 in Diabetic Nephropathy / Diabetic Kidney Disease as Measured by Albuminuria

Type 2 Diabetes Mellitus With Diabetic Nephropathy

United States
Akebia Therapeutics
Cyclerion Therapeutics

Completed

A Study of the Effect of IW-1973 on the Exercise Capacity of Patients With Heart Failure With Preserved Ejection Fraction (HFpEF) (CAPACITY-HFpEF)

Heart Failure With Preserved Ejection Fraction

United States, Canada
Asieris MediTech (Hong Kong) Co., Ltd.

Active, not recruiting

Efficacy and Safety of Cevira® in Patients With Cervical Histologic High-grade Squamous Intraepithelial Lesions (HSIL) (APRICITY)

Cervical Intraepithelial Neoplasia Grade 2/3

China
Laboratorios Osorio de Moraes Ltda.

Unknown

Study to Assess the Efficacy and Safety of "Pílulas de Lussen®" Compared to the Pyridium® in the Symptomatic Control of Dysuria (E01OSMPLS0108)

Dysuria
Laboratorios Osorio de Moraes Ltda.

Unknown

Phase III Open Study, Prospective, Multicenter, Randomized, Comparative to the Positive Control for Evaluating the Efficacy and Safety of Auris-Sedina in the Symptomatic Control of Otalgy in Patients With or Without Acute External Otitis. (E02OSMAS0108)

Otitis | Efficacy | Tolerability

Brazil
Eikon Therapeutics
Impact Therapeutics, Inc.

Recruiting

A First-in-human Study of PARP1 Selective Inhibitor, IMP1734, in Participants With Advanced Solid Tumors

Advanced Solid Tumor

Australia, United States
CRISPR Therapeutics AG

Active, not recruiting

A Safety and Efficacy Study Evaluating CTX130 in Subjects With Relapsed or Refractory Renal Cell Carcinoma (COBALT-RCC)

Renal Cell Carcinoma

United States, Australia, Canada, Netherlands
APRINOIA Therapeutics, LLC

Active, not recruiting

A First-in-Human Study to Assess Single Doses of APNmAb005 in Healthy Participants

Alzheimer Disease | Tauopathies | Healthy Volunteers

United States

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