Search clinical trials for: Ad-P53

Total 13362 results

M.D. Anderson Cancer Center
National Cancer Institute (NCI); Department of Health and Human Services

Terminated

Wild Type p53 Adenovirus for Oral Premalignancies

Mouth Cancer

United States
MultiVir, Inc.

Terminated

Safety and Efficacy of Intra-Arterial and Intra-Tumoral Ad-p53 With Capecitabine (Xeloda) or Anti-PD-1 in Liver Metastases of Solid Tumors and Recurrent Head and Neck Squamous Cell Cancer

Recurrent Head and Neck Cancer | Metastatic Solid Tumor Cancer

United States
Celltrion

Recruiting

A Study to Compare Efficacy, Pharmacokinetics, Pharmacodynamics and Safety of CT-P53 and Ocrevus in Patients With Relapsing-remitting Multiple Sclerosis

Relapsing-remitting Multiple Sclerosis

Poland
MultiVir, Inc.

Unknown

Safety and Efficacy of p53 Gene Therapy Combined With Immune Checkpoint Inhibitors in Solid Tumors.

Lymphoma | Solid Tumor

United States
Moy-Fincher-Chipps Facial Plastics and Dermatology

Unknown

To Evaluate and Compare p53 Epidermal Expression in Healthy Volunteers 3 Months After Treatment With a 2,940-nm Fractional Ablative Erbium Laser and Topical DNA Repair Enzymes

p53 Expression
Shenzhen SiBiono GeneTech Co.,Ltd

Unknown

rAd-p53 Gene Therapy for Advanced Oral and Maxillofacial Malignant Tumors (rAd-p53)

Advanced Oral and Maxillofacial Malignant Tumors

China
Addpharma Inc.

Completed

Evaluating the Pharmacokinetic Interaction Between AD-2101 and AD-2102

Hypertension

Korea, Republic of
Addpharma Inc.

Recruiting

A Study to Evaluate the Efficacy and Safety of AD-223

Hypertension,Essential

Korea, Republic of
Addpharma Inc.

Completed

A Study to Evaluate the Efficacy and Safety of AD-208

Androgenetic Alopecia

Korea, Republic of
Shenzhen SiBiono GeneTech Co.,Ltd

Unknown

rAd-p53 Gene Therapy for Advanced Malignant Thyroid Tumors

Advanced Malignant Thyroid Tumors

China
Addpharma Inc.

Completed

A Study to Evaluate the Efficacy and Safety of AD-209

Hypertension, Essential

Korea, Republic of
Addpharma Inc.

Recruiting

Phase III Study to Evaluate the Efficacy and Safety of AD-209

Hypertension,Essential

Korea, Republic of
Addpharma Inc.

Completed

Phase 3 Study to Evaluate the Efficacy and Safety of Co-administrated AD-2021 and AD-2022

Hypertension, Essential | Primary Hypercholesterolemia

Korea, Republic of
UCB Biopharma SRL

Recruiting

A Study to Evaluate the Efficacy and Safety of Rozanolixizumab in Adult Participants With Myelin Oligodendrocyte Glycoprotein (MOG) Antibody-associated Disease (MOG-AD) (cosMOG)

Myelin Oligodendrocyte Glycoprotein Antibody-associated Disease (MOG-AD)

United States, Australia, Belgium, Czechia, France, Germany, Italy, Japan, Korea, Republic of, Mexico, Spain, Sweden, Switzerland, Turkey, Portugal, United Kingdom, Brazil, Ukraine, Taiwan
National Cancer Institute (NCI)

Completed

Gene Therapy in Treating Patients With Advanced Bladder Cancer

Recurrent Bladder Cancer | Stage III Bladder Cancer | Stage IV Bladder Cancer | Transitional Cell Carcinoma of the Bladder | Stage I Bladder Cancer | Stage II Bladder Cancer

United States
Ad scientiam

Recruiting

Performance and Safety of a Digital Tool for Unsupervised Self-assessment of NMOSD (OPTIS)

Neuromyelitis Optica

United States, France
Shanghai Changzheng Hospital

Unknown

Arsenic Trioxide for Structural p53 Mutations

Refractory Cancer | Arsenic Trioxide | p53 Mutations | Intractable Cancer

China
Addpharma Inc.

Not yet recruiting

A Study to Evaluate the Efficacy and Safety of AD-224

Hypertension,Essential
Ruijin Hospital

Recruiting

Mutant p53-based Personalized Trial Using Decitabine and Arsenic Trioxide on AML/MDS (PANDA-T0)

P53 Mutation | Myeloid Malignancy | MDS | Aml

China
Addpharma Inc.

Completed

A Study to Evaluate the Safety and Pharmacokinetics of AD-221 Compared to Coadministration of AD-221A and AD-221B

Hyperlipidemias

Korea, Republic of
Addpharma Inc.

Not yet recruiting

A Study to Evaluate the Efficacy and Safety of Co-administration of AD-227A and AD-227B

Essential Hypertension
Novartis Pharmaceuticals

Completed

A Phase I Dose Escalation Study of CGM097 in Adult Patients With Selected Advanced Solid Tumors (CCGM097X2101)

Solid Tumor With p53 Wild Type Status

France, Germany, Singapore, Switzerland, United States
Zhejiang Hisun Pharmaceutical Co. Ltd.

Unknown

Evaluate the Safety and Efficacy of AD-35 Tablet in Subjects With Mild to Moderate Alzheimer's Disease (WAY)

Alzheimer's Disease

China
Shenzhen SiBiono GeneTech Co.,Ltd

Unknown

p53 Gene Therapy in Treatment of Diabetes Concurrent With Hepatocellular Carcinoma

HCC | Diabetes

China
Addpharma Inc.

Completed

A Study to Compare PK, PD and Safety of the AD-213-A and AD-2131

Gastroesophagus Reflux Disease

Korea, Republic of
Addpharma Inc.

Completed

A Study to Compare PK, PD and Safety of the AD-213-B and AD-2132

Gastroesophagus Reflux Disease

Korea, Republic of
Addpharma Inc.

Completed

Evaluating the Pharmacokinetic Interaction Between AD-2071 and AD-2072

Hypertension | Hyperlipidemias

Korea, Republic of
Mansoura University

Completed

Study of Bone Mineral Density and Trabecular Bone Score in Patients With Ankylosing Spondylitis

AS

Egypt
Addpharma Inc.

Completed

Evaluating the Pharmacokinetic Interaction Between AD-2011 and AD-2012

Hypertension | Hyperlipidemias

Korea, Republic of
Association de Recherche Bibliographique pour les...
Centre Hospitalier Princesse Grace; Universite Cote d'Azur

Completed

Rehabilitation of Facial Emotion Recognition in Alzheimer's Disease

Family Caregivers | Alzheimer's Dementia (AD)

Monaco
Mansoura University

Completed

Lymph Node Ratio and Kras Mutation in R Colon Cancer

Colon Cancer Stage III

Egypt
Hamad Medical Corporation

Unknown

Corticosteroids and Anti TNF in Methotrexate Inadequate Responder Rheumatoid Arthritis Patient

RHEUMATOID ARTHRITIS

Qatar
Shenzhen SiBiono GeneTech Co.,Ltd

Unknown

Trans-catheter Arterial Embolization Combined With p53 Gene Therapy for Treatment of Advanced Hepatocellular Carcinoma

Advanced Hepatocellular Carcinoma (HCC)

China
National Cancer Institute (NCI)

Completed

Gene Therapy in Preventing Cancer in Patients With Premalignant Carcinoma of the Oral Cavity or Pharynx

Lip and Oral Cavity Cancer | Oropharyngeal Cancer | Tongue Cancer | Stage 0 Lip and Oral Cavity Cancer | Stage 0 Oropharyngeal Cancer

United States
Shanghai Synergy Pharmaceutical Sciences Co., Ltd.

Completed

Safety and Pharmacokinetic of Donepezil Pamoate in Healthy Subjects

AD

China
Affiliated Hospital of Jiangnan University

Completed

Association Between Ferroptosis and Epilepsy

Epilepsy

China
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Completed

Gene Therapy Plus Radiation Therapy in Treating Patients With Non-Small Cell Lung Cancer

Lung Cancer

United States
Addpharma Inc.

Recruiting

A Study to Evaluate the Efficacy and Safety of AD-218

Mixed Dyslipidemia

Korea, Republic of
Centre Hospitalier Princesse Grace
Association de Recherche Bibliographique pour les Neurosciences; Universite...

Completed

Rehabilitation of Facial Emotion Recognition in Alzheimer's Disease (EYE-TAR(MA))

Alzheimer Dementia | Family Caregivers
Boston University

Completed

Clinic-Based Atopic Dermatitis Therapeutic Patient Education (AD-TPE)

Atopic Dermatitis

United States
National Cancer Institute (NCI)

Completed

Gene Therapy Plus Chemotherapy in Treating Patients With Breast Cancer

Breast Cancer

United States
University of Texas Southwestern Medical Center
National Cancer Institute (NCI)

Completed

Gene Therapy in Treating Patients With Advanced Recurrent or Persistent Ovarian Cancer or Primary Peritoneal Cancer

Ovarian Cancer | Peritoneal Cavity Cancer

United States
Aventis Pharmaceuticals

Unknown

Gene Therapy in Treating Patients With Recurrent Head and Neck Cancer

Head and Neck Cancer

United States
Corporal Michael J. Crescenz VA Medical Center

Completed

Study of Default Options in Advance Directives

Idiopathic Pulmonary Fibrosis | COPD | Congestive Heart Failure | Malignancy | Severe or Very Severe Airflow Obstruction and/or Receiving or Eligible to Receive Long-term Oxygen Therapy | Other Interstitial Lung Disease Without Curative Therapy | NYHA Class IV or NYHA Class III Plus 1 Hospitalization... and other conditions

United States
Ad scientiam

Not yet recruiting

A Usability Validation of the MuCopilot Mobile Application, a Digital Tool for the Unsupervised Objective Assessment of Cystic Fibrosis (MuControl-Sum)

Cystic Fibrosis

France
Ad scientiam

Recruiting

Descriptive Analysis of Real-world Data Collected With ME&MGopen

Myasthenia Gravis

United Kingdom, United States, Canada
Hamad Medical Corporation

Recruiting

Effect of Human Plasma Protein Transfusion With and Without Crystalloids During Major Liver Resection Surgeries

Coagulation; Intravascular | Fluid Electrolyte Disorders

Qatar
University of Palermo

Completed

Adrenal Function in GHD Children

Growth Hormone Treatment | Adrenal; Functional Disturbance

Italy
Federal University of São Paulo

Completed

Oral Isotretinoin for Photoaging: Results of a Randomized Controlled Phase II Trial

Photoaging | Epidermal p53 Expression

Brazil
University of Pittsburgh
National Institute of Mental Health (NIMH)

Completed

Prevention of Depression in Spouses of People With Cognitive Impairment

Depression

United States

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