Search clinical trials for: Artesunate

Total 237 results

Merck Sharp & Dohme LLC

Recruiting

A Study to Evaluate Antimalarial Activity and Safety of MK-7602 in Healthy Adults (MK-7602-003)

Malaria

Australia
UNC Lineberger Comprehensive Cancer Center

Not yet recruiting

Pharmacokinetics of Intravaginal, Self-administered Artesunate Vaginal Pessaries Among Women in Kenya

Cervix Cancer | Cervix Intraepithelial Neoplasia Grade 3 | Cervix; Intraepithelial Neoplasia, Grade I | Cervix; Intraepithelial Neoplasia, Grade II

Kenya
Frantz Viral Therapeutics, LLC
Anal Dysplasia Clinic MidWest; Laser Surgery Care, LLC

Recruiting

Artesunate Ointment for the Treatment of Anal HSIL in HIV-negative Participants (ART-AIN IIB-2)

Anal High-grade Squamous Intraepithelial Lesion | Anal HSIL | Anal HPV Infection

United States
London School of Hygiene and Tropical Medicine

Not yet recruiting

Parasite Clearance and Protection From Infection (PCPI) in Zambia

Malaria

Zambia
UNC Lineberger Comprehensive Cancer Center
Gilead Sciences

Recruiting

Artesunate Pessaries (Vaginal Inserts) for Cervical Precancer in Kenya

Precancerous Conditions | Cervix Cancer | Cervical Precancer | Cervix Neoplasm

Kenya
Frantz Viral Therapeutics, LLC
The Cleveland Clinic

Recruiting

Phase II Study of Artesunate Ointment for the Treatment of Vulvar High Grade Squamous Intraepithelial Lesions (Vulvar HSIL, VIN2/3) (ART-VIN IIB)

Vulvar Diseases | HPV Infection | Vulvar HSIL | High Grade Intraepithelial Neoplasia | HPV Disease | Pre-Cancerous Dysplasia | Vin II | Vin III | VIN, Usual Type | VIN 2 of Usual Type | VIN 3 of Usual Type | VIN Grade 2 | VIN Grade 3

United States
Joseph C. Wu

Not yet recruiting

Open-Label Dose-Escalation Treatment Study of Patients With IPF (DIAMOND)

Idiopathic Pulmonary Fibrosis

United States
University of Oxford

Not yet recruiting

A Study to Find Out if a Combination of 3 Medicines for the Treatment of Malaria Works as Well and is as Safe and Tolerable as Combinations of 2 Medicines (FD-TACT)

Uncomplicated Plasmodium Falciparum Malaria
Centre de Recherche Médicale de Lambaréné
Institute of Tropical Medicine, University of Tuebingen

Not yet recruiting

A Crossover Bioavailability Clinical Trial of Parenteral Pyronaridine and Artesunate

Severe Malarial Treatment

Gabon
Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co...

Recruiting

A Study of FZ-AD004 in Patients With Advanced Solid Tumors

Advanced and Metastatic Solid Tumor

China
Muhimbili University of Health and Allied Sciences
Uppsala University; The Swedish Research Council

Not yet recruiting

Triple Artemisinin-based Combination Therapy for Delaying Drug Resistance Development - a Randomized Clinical Trial (3ACT)

Uncomplicated Plasmodium Falciparum Malaria

Tanzania
National Institute of Allergy and Infectious Diseases...
University of Maryland, Baltimore; Makerere University

Recruiting

Pharmacokinetic Study of IV Artesunate to Treat Children With Severe Malaria

Plasmodium Falciparum Infection

Uganda
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate...

Recruiting

Phase IIa Proof of Concept Study of M5717-Pyronaridine in Adults and Adolescents With Acute Uncomplicated Plasmodium Falciparum Malaria (CAPTURE 1)

Acute Malaria

Burkina Faso, Gabon, Mozambique, Uganda
SWOG Cancer Research Network
National Cancer Institute (NCI); Genentech, Inc.

Recruiting

Testing Drug Treatments After CAR T-cell Therapy in Patients With Relapsed/Refractory Diffuse Large B-cell Lymphoma

Diffuse Large B-Cell Lymphoma | Recurrent Diffuse Large B-Cell Lymphoma | Refractory Diffuse Large B-Cell Lymphoma | Primary Mediastinal (Thymic) Large B-Cell Lymphoma | Grade 3b Follicular Lymphoma | Transformed Follic Lymph to Diff Large B-Cell Lymphoma | Transformed Marg Zone Lymph to Diff...

United States
Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co...

Recruiting

A Study of FDA022-BB05 in Subjects With Advanced Solid Malignant Tumors

Advanced Solid Tumors

China
University Hospital Tuebingen
Sanaria Inc.; University of Oxford

Not yet recruiting

Comparing Safety and Protective Efficacy of Vaccine Candidate PfSPZ-CVac and MVA ME-TRAP/ ChAd63 ME-TRAP in Adults

Malaria
Amivas (US), LLC

Recruiting

Observational Study of the Safety of Intravenous Artesunate Treatment of Pregnant Women and Their Infants

Pregnancy | Malaria

United States
Nepal Health Research Council
World Health Organization

Recruiting

Add-on Study on WHO Solidarity Trial Plus for COVID-19 in Nepal

COVID-19

Nepal
Institut National de la Santé Et de la Recherche...
Imagine Institute

Recruiting

Evaluation of the Effect of Artesunate in Friedreich Ataxia (FA) (ARTEMIS)

Friedreich Ataxia

France
University of Yaounde 1
Biotechnology Center (BTC), University of Yaounde I, Cameroon; National Malaria... and other collaborators

Not yet recruiting

Efficacy and Safety of Artesunate-amodiaquine and Artemether-lumefantrine for the Treatment of Malaria in Cameroon

Falciparum Malaria
Sanjay Gandhi Postgraduate Institute of Medical...
St George's University of London, London, UK

Recruiting

Safety and Efficacy of Artesunate & Curcumin in Crohn's Disease

Crohn's Disease

India
University of Maryland, Baltimore
National Centre for Parasitology, Entomology and Malaria Control, Cambodia; Institut Pasteur du Cambodge

Recruiting

Rigorous Assessment of P. Vivax Relapses and Primaquine Efficacy for Radical Cure

Vivax Malaria

Cambodia
Shin Poong Pharmaceutical Co. Ltd.

Recruiting

The Safety and Efficacy of Pyronaridine-artesunate (Pyramax® or Artecom®)in COVID-19 Patients (PROVIDENCE)

Covid19

Philippines
Novartis Pharmaceuticals
Wellcome Trust; European and Developing Countries Clinical Trials Partnership...

Recruiting

To Evaluate Efficacy, Safety, Tolerability and PK of Intravenous Cipargamin in Participants With Severe Plasmodium Falciparum Malaria

Severe Malaria

Burkina Faso, India, Rwanda, Congo, The Democratic Republic of the, Gabon, Nigeria, Côte D'Ivoire, Kenya
Frantz Viral Therapeutics, LLC
M.D. Anderson Cancer Center; University of Michigan; The Cleveland Clinic; Amarex... and other collaborators

Recruiting

Artesunate Vaginal Inserts for the Treatment of Cervical Intraepithelial Neoplasia (CIN2/3) (ART-CIN_IIB)

HPV Infection | CIN 2/3 | Cervical Dysplasia | Pre-Cancerous Dysplasia | HPV Related Disease

United States
University of Oxford
Mahidol Oxford Tropical Medicine Research Unit

Recruiting

A Trial to Compare the Efficacy, Safety and Tolerability of Combinations of 3 Anti-malarial Drugs Against Combina-tions of 2 Anti-malarial Drugs. (DeTACT-Africa)

Plasmodium Falciparum Malaria (Uncomplicated)

Burkina Faso, Congo, The Democratic Republic of the, Gambia, Guinea, Nigeria, Niger, Rwanda, Tanzania
Armed Forces Research Institute of Medical Sciences...
National Center for Parasitology, Entomology, and Malaria Control (CNM); Naval...

Recruiting

Drug Combinations of Atovaquone-Proguanil (AP) With ACT (APACT)

Plasmodium Falciparum Malaria (Drug Resistant)

Cambodia
Sun Yat-sen University
The First Affiliated Hospital of Nanchang University; Tongji Hospital; First... and other collaborators

Recruiting

Efficacy and Safety of Artesunate Plus Standard of Care in Active Lupus Nephritis (AURORA)

Lupus Nephritis

China
St George's, University of London

Recruiting

A Safety and Effectiveness Study of Pre-operative Artesunate in Stage II/III Colorectal Cancer (NeoART)

Colorectal Cancer | Bowel Cancer

United Kingdom
Frantz Viral Therapeutics, LLC
University of California, San Francisco; Laser Surgery Care; Amarex CRO; Anal Dysplasia...

Active, not recruiting

Artesunate Suppositories for the Treatment of HIV-negative Patients With Intra-anal HSIL (anal HSIL HIV-)

HPV Infection | Anal Dysplasia | Anal High Grade Squamous Intraepithelial Lesion | Anal Precancerous Condition | AIN 2/3 | HPV Disease

United States
National Cancer Institute (NCI)
The Lymphoma Academic Research Organisation

Active, not recruiting

Brentuximab Vedotin and Combination Chemotherapy in Treating Patients With Stage II-IV HIV-Associated Hodgkin Lymphoma

HIV Infection | Ann Arbor Stage III Hodgkin Lymphoma | Ann Arbor Stage IIIA Hodgkin Lymphoma | Ann Arbor Stage IIIB Hodgkin Lymphoma | Ann Arbor Stage IV Hodgkin Lymphoma | Ann Arbor Stage IVA Hodgkin Lymphoma | Ann Arbor Stage IVB Hodgkin Lymphoma | Classic Hodgkin Lymphoma | Ann Arbor Stage II Hodgkin... and other conditions

United States, France
Centers for Disease Control and Prevention
Ministry of Health, Liberia

Completed

Efficacy of Artesunate-amodiaquine and Artemether-lumefantrine for Treatment of Plasmodium Falciparum Malaria in Liberia

Malaria | Plasmodium Falciparum | Uncomplicated Malaria

Liberia
University of Oxford
Mahidol Oxford Tropical Medicine Research Unit

Completed

A Trial to Compare the Efficacy, Safety and Tolerability of Combinations of 3 Anti-malarial Drugs Against Combinations of 2 Anti-malarial Drugs (Asia) (DeTACT-ASIA)

Plasmodium Falciparum Malaria (Uncomplicated)

Cambodia, Bangladesh
University of Oxford
Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd.; National Institute... and other collaborators

Completed

Study to Compare Feasibility of 1-step Injectable Artesunate vs. Conventional 2-step Injectable Artesunate (1STEP-AS)

Severe Malaria

Congo, The Democratic Republic of the
Liverpool School of Tropical Medicine
London School of Hygiene and Tropical Medicine; Bill and Melinda Gates Foundation and other collaborators

Completed

Malaria as a Risk Factor for COVID-19 in Western Kenya and Burkina Faso (MALCOV)

Covid-19 | Malaria

Burkina Faso, Kenya
Ministry of Public Health, Democratic Republic...
Centers for Disease Control and Prevention; Global Fund

Active, not recruiting

Test Efficacy Study on the Recommended Antimalarial Drugs in the Democratic Republic of the Congo (TES2022)

Uncomplicated Plasmodium Falciparum Malaria

Congo, The Democratic Republic of the
Medicines for Malaria Venture
Shin Poong Pharmaceutical Co. Ltd.

Completed

Relative Bioavailability of Pyronaridine-artesunate in Tablet and Granule Formulations in Healthy Volunteers

Malaria

Korea, Republic of
Medicines for Malaria Venture
Shin Poong Pharmaceuticals

Completed

Drug Interaction Study of Pyronaridine-artesunate & Metoprolol, & Redosing Study of Pyronaridine-artesunate

Malaria

Switzerland
Centro de Investigação em Saúde de Manhiça
United States Agency for International Development (USAID)

Active, not recruiting

In Vivo Efficacy of Artemether-Lumefantrine, Amodiaquine-Artesunate, Dihydroartemisinin-Piperaquine, and Pironaridine-Artesunate in Mozambique (MEFI_IV)

Malaria

Mozambique
Sidney Kimmel Comprehensive Cancer Center at Johns...
Frantz Viral Therapeutics, LLC

Active, not recruiting

Artesunate Ointment for the Treatment of High Grade Vulvar Intraepithelial Neoplasia (HSIL VIN2/3) (ART-VIN)

Vulvar Diseases | Vulvar Dysplasia | HPV-Related Vulvar Intraepithelial Neoplasia | Preinvasive Vulvar Disease | Vulva Intraepithelial Neoplasia

United States
Sunnybrook Health Sciences Centre
University of British Columbia; AbbVie; World Health Organization; Apotex Inc.; Arch...

Active, not recruiting

Treatments for COVID-19: Canadian Arm of the SOLIDARITY Trial (CATCO)

COVID-19

Canada
Shin Poong Pharmaceutical Co. Ltd.

Completed

The Efficacy and Safety of Pyramax in Mild to Moderate COVID-19 Patients (Phase3)

COVID-19

Korea, Republic of, Colombia, Argentina, Poland, Chile, United Kingdom
London School of Hygiene and Tropical Medicine

Completed

Gametocytocidal and Transmission-blocking Efficacy of ASAQ and ALAQ With or Without PQ in Mali (NECTAR4)

Malaria,Falciparum

Mali
University of Oxford

Terminated

Compare the Effectiveness Between Existing Treatment and New Treatment (RDM)

P. Falciparum Malaria

Thailand
Shin Poong Pharmaceutical Co. Ltd.

Completed

Pilot Clinical Trial to Explore Efficacy and Safety of Pyramax in Mild to Moderate COVID-19 Patients

COVID-19

Korea, Republic of
Danish Headache Center

Completed

The Effect of Levcromakalim Infusion on the Cranial Arteries Over Several Hours Using a High Resolution MRA Technique in a Randomized, Double-blind Placebo-controlled Design in Healthy Volunteers.

Headache | Dilatation of Cranial Arteries; MMA, STA and MCA

Denmark
Medicines for Malaria Venture
Shin Poong Pharmaceuticals; Institute of Tropical Medicine, University of Tuebingen

Completed

Pyronaridine and Artesunate (3:1) in Children With Acute Uncomplicated Plasmodium Falciparum Malaria

Uncomplicated Plasmodium Falciparum Malaria

Gabon
Princess Nourah Bint Abdulrahman University

Withdrawn

Evaluating the Efficacy of Artesunate in Adults With Mild Symptoms of COVID-19

Corona Virus Infection | Covid 19 Positive

Saudi Arabia
University of Ibadan
Shin Poong Pharm Co Ltd 161 yoksam-ro, Gangnam-Gu Seoul 135-925, Korea; Institute...

Completed

Efficacy and Safety of Pyronaridine-Artesunate Versus Artemether-Lumefantrine

Plasmodium Falciparum Malaria | Uncomplicated Malaria | Malaria Fever

Nigeria
University of Oxford

Completed

Randomised Trial of 3 Artemisinin Combination Therapy for Malaria in Pregnancy (DMA)

Malaria

Thailand

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