Search clinical trials for: Chromosome Aberrations

Total 2761 results

Novartis Pharmaceuticals

Not yet recruiting

Clinical Study of Asciminib in Previously Treated Indian Patients With Ph+ CML-CP Without T315I Mutation and in Patients With Ph+ CML-CP With T315I Mutation (ASC4INDIA)

Philadelphia Chromosome-Positive Chronic Myeloid Leukemia in Chronic Phase
Gattaca Genomics

Recruiting

Embryo Assessment Utilizing Timelapse Imaging in Conjunction With Preimplantation Genetic Testing for Aneuploidy With Next Generation Sequencing

Infertility | Aneuploidy | Infertility, Female | Infertility, Male | IVF

United States
M.D. Anderson Cancer Center
Ascentage Pharma Group Inc.

Not yet recruiting

A Phase I Study of Decitabine, Lisaftoclax, and Olverembatinib in Patients With Advanced Chronic Myeloid Leukemia and Philadelphia Chromosome-Positive Acute Myeloid Leukemia

Advanced Chronic Myeloid Leukemia | Philadelphia Chromosome-Positive Acute Myeloid Leukemia

United States
University of Colorado, Denver
Children's Hospital Colorado

Recruiting

Generating Advancements Through Longitudinal Analysis in X and Y Variations (GALAXY) (GALAXY)

Sex Chromosome Aneuploidy

United States
Rigshospitalet, Denmark

Not yet recruiting

Preimplantation Genetic Testing for Aneuploidy (PGT-A) in Women Aged 37-41 Years

Infertility

Denmark
Meyer Children's Hospital IRCCS

Recruiting

The Role of Renal Progenitors and Polyploid Tubular Cell Response in Glomerular and Tubular Diseases

Nephropathy

Italy
Erasmus Medical Center

Not yet recruiting

Detection of Aneuploidy in Cell Free DNA to Improve the Sensitivity of Diagnostic Peritoneal Lavage in Gastric Cancer

Gastric Cancer

Netherlands
M.D. Anderson Cancer Center
Novartis Pharmaceuticals

Not yet recruiting

Phase II Study of the Combination of Blinatumomab and Asciminib in Patients With Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia

Acute Lymphoblastic Leukemia | Philadelphia Chromosome-Positive

United States
Institute of Hematology & Blood Diseases Hospital...

Recruiting

Detecting Minimal Residual Diseases (MRD) and Monitoring Clonal Evolution Using Ultrasensitive Chromosomal Aberrations Detection (UCAD) in Multiple Myeloma

Multiple Myeloma
Nanfang Hospital, Southern Medical University

Recruiting

A Single-arm, Open-label Study of Olverembatinib, CD3/CD19 Bispecific T-cell Engager, and Chidamide in Patients With Newly Diagnosed Ph+ALL (ABC)

Acute Lymphoblastic Leukemia | Philadelphia Chromosome | Adult ALL | Philadelphia-Positive ALL | IKZF1 Gene Mutation

China
University College Cork

Not yet recruiting

Assessment of Diastolic Function During the Transitional Period and Infancy Using Serial Echocardiography (DiFuSE)

Gestational Diabetes | Neonatal Encephalopathy | Diastolic Dysfunction | Trisomy 21 | Transient Tachypnea of the Newborn | Small for Gestational Age at Delivery

Ireland
Changhai Hospital

Not yet recruiting

Analyzing the Urine During BCG Instillation in Bladder Cancer Patients for Disease Followup

Bladder Cancer

China
Tianjin Central Hospital of Gynecology Obstetrics

Recruiting

The Relationship Between Fetal Membrane Thickness and Fetal Chromosomal Aneuploidies (PLACE2102)

Chromosome Aberrations

China
National Cancer Institute (NCI)

Not yet recruiting

A Study Comparing the Combination of Dasatinib and Chemotherapy Treatment With or Without Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or Philadelphia Chromosome-Like (Ph-Like) ABL-Class B-Cell Acute Lymphoblastic Leukemia (B-ALL)

B Acute Lymphoblastic Leukemia
Volastra Therapeutics, Inc.

Recruiting

A Study of Sovilnesib in Subjects With Ovarian Cancer

Fallopian Tube Cancer | Primary Peritoneal Carcinoma | High Grade Serous Adenocarcinoma of Ovary | Chromosomal Instability

United States
Goethe University
German Federal Ministry of Education and Research; Deutsche Leukämie- & Lymphom-Hilfe

Recruiting

Randomized Trial in Adult de Novo Ph Positive ALL With Chemotherapy, Imatinib or Ponatinib, Blinatumomab and SCT (GMALL-EVOLVE)

Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia

Germany
Professor Ernest Hung-Yu Ng

Not yet recruiting

Microfluidic Chip vs Density Gradient Centrifugation on the Euploidy Rate of Pre-implantation Genetic Testing

Infertility | Aneuploidy | Genetic Disease | Chromosomal Rearrangement

China
Eyup Hakan Duran

Recruiting

Preimplantation Genetic Testing for Aneuploidy Counseling (PGT-A)

Patient Education

United States
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Periodontitis and Inflammation in Children With Down Syndrome/Trisomy 21: Study on Biological Samples (NT21)

Periodontitis | Trisomy 21

France
Volastra Therapeutics, Inc.

Recruiting

A Phase I/II Study of VLS-1488 in Subjects With Advanced Cancer

Gastric Adenocarcinoma | Uterine Carcinosarcoma | Triple Negative Breast Cancer | Advanced Solid Tumor | Head and Neck Squamous Cell Carcinoma | Esophageal Adenocarcinoma | Esophageal Squamous Cell Carcinoma | Transitional Cell Carcinoma of Bladder | Colorectal Adenocarcinoma | Gastroesophageal Junction... and other conditions

United States
CHU de Quebec-Universite Laval

Recruiting

Scaling a Decision Aid on Prenatal Screening for Trisomy 21, 18 and 13 (PEGASUS-II)

Decision Aid

Canada
Taizhou Hospital of Zhejiang Province affiliated...
Sir Run Run Shaw Hospital; First Affiliated Hospital of Wenzhou Medical University and other collaborators

Recruiting

Application of Chromosomal Instability in Early Diagnosis of Biliary Tract Carcinoma

Biliary Tract Carcinoma

China
Federico II University

Recruiting

A Pilot Study for Implementation of First Trimester Screening of Aneuploidies in Campania Region (PISTA)

Aneuploidy

Italy
Masonic Cancer Center, University of Minnesota

Recruiting

MT2021-08T Cell Receptor Alpha/Beta Depletion PBSC Transplantation for Heme Malignancies

Acute Myeloid Leukemia | Juvenile Myelomonocytic Leukemia | Acute Lymphoblastic Leukemia | AML | Acute Leukemia | Neurofibromatosis 1 | Hematologic Malignancy | Myelodysplasia | Minimal Residual Disease | Chromosome Abnormality | Monosomy 7 | Remission | Somatic Mutation | Cytogenetic Abnormality | TP53 | Fetal Hemoglobin | Intrachromosomal Amplification of Chromosome... and other conditions

United States
Centre Hospitalier Universitaire, Amiens
Centre Henri Becquerel; Hôpital Jeanne de Flandre LIlle

Recruiting

Evaluation of Optical Genome Mapping in Phi Negative Myeloproliferative Neoplasia in the Detection of Acquired Cytogenetic Abnormalities (MYELOCARTOCH)

Myeloproliferative Neoplasm | Optical Genome Mapping | Cytogenetics | Clonality | Prognostic Stratification

France
Institute of Hematology & Blood Diseases Hospital

Recruiting

Pediatric-inspired Regimen Combined With Venetoclax for Adolescent and Adult Patients With de Novo Philadelphia Chromosome-Negative Acute Lymphoblastic Leukemia

Precursor Cell Lymphoblastic Leukemia-Lymphoma

China
Institute of Hematology & Blood Diseases Hospital...

Recruiting

Olverembatinib Combined With Reduced-Intensity Chemotherapy and Venetoclax for de Novo Ph+ ALL

Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia

China
Assisting Nature

Recruiting

Invasive PGT-A Embryo Selection Versus Non Invasive PGT-A Assisted Embryo Selection

Infertility | Aneuploidy | Chromosome Abnormality

Greece
Assisting Nature

Recruiting

Time Lapse Assisted Embryo Selection Versus Non Invasive PGT-A Assisted Embryo Selection

Infertility | Aneuploidy | Chromosome Abnormality

Greece
University of Michigan
National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health...

Recruiting

Self-Supporting Nasopharyngeal Airway (ssNPA) Treating Upper Airway Obstruction in Hypotonia

Obstructive Sleep Apnea | Down Syndrome | Tolerance | Trisomy 21 | Hypertonia, Muscle | Nasal Airway Obstruction

United States
Instituto Valenciano de Infertilidade de Lisboa
Universidade Nova de Lisboa

Recruiting

Nuclear Magnetic Resonance for Embryo Ploidy Selection

Infertility | Aneuploidy

Portugal
Novartis Pharmaceuticals

Recruiting

A Study to Investigate Tolerability and Efficacy of Asciminib (Oral) Versus Nilotinib (Oral) in Adult Participants (≥18 Years of Age) With Newly Diagnosed Philadelphia Chromosome Positive Chronic Myelogenous Leukemia in Chronic Phase (Ph+ CML-CP) (ASC4START)

Philadelphia Chromosome-Positive Chronic Myeloid Leukemia

Germany, United Arab Emirates, Greece, Czechia, Hungary, United States, Oman, Malaysia, France, Turkey, Bulgaria, Canada, Slovakia, Argentina, Italy, Jordan, Romania, South Africa, Korea, Republic of, Singapore, United Kingdom, Sw... and more
University of Washington
Incyte Corporation

Recruiting

Chemotherapy (DA-EPOCH+/-R) and Targeted Therapy (Tafasitamab) for the Treatment of Newly-Diagnosed Philadelphia Chromosome Negative B Acute Lymphoblastic Leukemia

B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative

United States
University of Aarhus
Aarhus University Hospital

Recruiting

Endocrine, Metabolic, Cardiovascular and Immunological Aspects of Sex Chromosome Abnormalities in Relation to Genotype (EMKISCA)

Cardiovascular Diseases | Turner Syndrome | Metabolic Disease | Klinefelter Syndrome | Immunologic Disease | Sex Chromosome Abnormality

Denmark
Lei Li

Recruiting

Chromosomal Instability in Ovarian Cancer

Epithelial Ovarian Cancer | High-grade Serous Ovarian Carcinoma | Survival Outcomes | Overall Survival | Progression-free Survival | Chromosomal Instability | Somatic Copy Number Distortion | Minimal Residual Lesions

China
Vanderbilt University Medical Center
Vanderbilt Kennedy Center

Recruiting

Cholinergic Integrity in Down Syndrome in Association With Aging, Alzheimer's Disease Pathology, and Cognition

Alzheimer Disease | Down Syndrome | Down Syndrome, Partial Trisomy 21

United States
Chang Gung Memorial Hospital

Recruiting

Investigation and Diagnosis of the Chromosome Variation in Donated/Abandoned Blastocyst

Recurrent Miscarriage | Chromosome Translocation | Genetic Disorders in Pregnancy

Taiwan
Anova Enterprises, Inc

Recruiting

AnovaOS Network Powered Patient Registry

Neoplasms | Infectious Disease | External Causes of Morbidity and Mortality | Pregnancy, Childbirth and the Puerperium | Diseases of the Blood and Blood-Forming Organs and Certain Disorders Involving the Immune Mechanism (D50-D89) | Endocrine, Nutritional and Metabolic Diseases (E00-E89) | Mental... and other conditions

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI); Astex Pharmaceuticals, Inc.

Recruiting

ASTX727 and Dasatinib for the Treatment of Newly Diagnosed Philadelphia Chromosome or BCR-ABL Positive Chronic Myeloid Leukemia in Chronic Phase

Chronic Phase Chronic Myelogenous Leukemia | Philadelphia Chromosome Positive | BCR-ABL1 Positive Chronic Myelogenous Leukemia | BCR-ABL1 Positive

United States
Novartis Pharmaceuticals

Recruiting

Study to Determine the Dose and Safety of Asciminib in Pediatric Patients With Chronic Myeloid Leukemia

Myeloid Leukemia, Philadelphia Positive

Korea, Republic of, Germany, France, Greece, Hungary, Italy, Japan, Russian Federation, Thailand, Turkey, China, United States, Netherlands, Poland
OHSU Knight Cancer Institute
AbbVie; Oregon Health and Science University

Recruiting

Venetoclax, Dasatinib, Prednisone, Rituximab and Blinatumomab for the Treatment of Newly Diagnosed or Relapsed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia or Mixed Phenotype Acute Leukemia

B Acute Lymphoblastic Leukemia | Recurrent B Acute Lymphoblastic Leukemia | Recurrent Mixed Phenotype Acute Leukemia | B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1 | Mixed Phenotype Acute Leukemia

United States
University Hospital, Brest

Recruiting

Biocollection in MyeloDysplastic Syndrome (P-MDS) (P-MDS)

Myelodysplastic Syndromes | Chromosome Abnormality | Acute Myeloid Leukemia With Multilineage Dysplasia | Myelodysplastic Syndrome With Ring Sideroblasts | Myelodysplastic Anemia | Myelodysplastic Syndrome With Isolated Del(5Q)

France
Centre Hospitalier Universitaire de la Réunion

Recruiting

Qualitative Exploratory Study Among Reunionese Women and Their Partners Who Have a Child With Trisomy 21 (QUALI-21)

Down Syndrome

Réunion
IVI Vigo
Instituto Valenciano de Infertilidad, IVI VALENCIA; Juno Therapeutics, Inc.

Not yet recruiting

Embryos With Preimplantation Genetic Testing for Aneuploidies (PGT-A) Inconclusive Result: Clinical Implications

Embryo Disorder
Olive Fertility Centre
Thermo Fisher Scientific, Inc; Sequence46

Recruiting

Noninvasive Chromosomal Screening for Embryo Selection Trial (NICEST)

Infertility | Aneuploidy

Canada
Gruppo Italiano Malattie EMatologiche dell'Adulto

Recruiting

Sequential Treatment With Ponatinib and Blinatumomab vs Chemotherapy and Imatinib in Newly Diagnosed Adult Ph+ ALL

ALL, Adult | Philadelphia-Positive ALL | Acute Lymphoblastic Leukemia (Philadelphia Chromosome Positive)

Italy
Washington University School of Medicine
Dickson, Patricia I., M.D.; Milbrandt, Jeffrey, MD, PhD; Mitra, Rob, PhD; Turner...

Recruiting

Chromosome 9 P Minus Syndrome

Chromosome 9P Deletion Syndrome | 9p Minus Syndrome | Alfi Syndrome | 9P Monosomy | 9P Partial Monosomy Syndrome

United States
Reproductive & Genetic Hospital of CITIC-Xiangya

Recruiting

Preimplantation Genetic Testing for Aneuploidy of Polar Bodies

Subfertility

China
The University of Hong Kong

Recruiting

RCT of niPGT for Aneuploidy and Morphology Compared With Morphology Alone in IVF

Preimplantation Diagnosis

China
Peking University Third Hospital
The Second Hospital of Hebei Medical University; First Affiliated Hospital,... and other collaborators

Recruiting

Embryo Selection by Noninvasive Preimplantation Genetic Test (ESNi-PGT)

Infertility | Chromosome Abnormality

China

Search clinical trials for: Chromosome Aberrations

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