Search clinical trials for: Disease Progression

Total 382016 results

Splice Bio

Recruiting

An Observational Study in Subjects to Follow the Progression of Stargardt Disease Type 1 (STGD1) Caused by Bi-Allelic Autosomal Recessive Mutations in the ABCA4 Gene (POLARIS)

Stargardt Disease | Stargardt's Disease | STGD1 | Stargardt
Hospices Civils de Lyon

Recruiting

Campylobacter Spp. Bone and Joint Infection: a Retrospective Cohort Study (Campylo-BJI)

Campylobacter Infections

France
University of Southern California
National Cancer Institute (NCI)

Recruiting

An Integrative Multi-Omic Characterization of Head and Neck Carcinogenesis, Progression and Recurrence

Head and Neck Carcinoma

United States
Ospedale San Raffaele

Recruiting

Genetics in the Progression of Nephropathies

Hypertension | AKI | CKD | Hematologic Malignancy | Ckd-Mbd | ADPKD | Bone Marrow Transplant Complications | CKD (Chronic Kidney Disease) Stage 5D

Italy
Ospedale San Raffaele
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico

Recruiting

Identification of New Biological Markers for the Progression of Mycobacterium Abscessus-induced Lung Disease in Cystic Fibrosis (BioMol-MA)

Non-Tuberculous Mycobacterial Pneumonia | Cystic Fibrosis Lung

Italy
Suzhou Kerui Medical Technology Co., Ltd
Suzhou Mingshi Optical Technology Co., Ltd

Recruiting

A Clinical Trial to Evaluate the Efficacy and Safety of Defocusing Lenses in Delaying Myopia Progression

Myopia

China
Jules Bordet Institute
RayzeBio, Inc.

Not yet recruiting

A Phase I Study to Assess the Tolerability of 225Ac-DOTATATE in Patients With Refractory and Relapsing Multiple Myeloma Expressing Somatostatin Receptors (AcTRESS)

Multiple Myeloma in Relapse | Multiple Myeloma, Refractory | Multiple Myeloma Progression

Belgium
Casa Sollievo della Sofferenza IRCCS
IRCCS Ospedale San Raffaele

Not yet recruiting

Tumor Cell Plasticity and Aggressiveness in Human Non-small Cell Lung Cancer

Lung Neoplasms | Progression
The First Affiliated Hospital of Soochow University

Not yet recruiting

Treatment of High-risk Newly Diagnosed Multiple Myeloma With Minimal Residual Disease Detection

Multiple Myeloma | Newly Diagnosed | MRD | High Risk
Tianjin Eye Hospital

Not yet recruiting

To Evaluate the Efficacy and Safety of an Defocus Lens in Slowing the Progression of Myopia

Myopia, Progressive

China
Pfizer

Not yet recruiting

Real-World Effectiveness of High-Dose Tafamidis on Neurologic Disease Progression in Mixed-Phenotype Transthyretin Amyloid Cardiomyopathy

Transthyretin Amyloidosis Cardiomyopathy (ATTR-CM)

United States
Amsterdam UMC, location VUmc
Maastricht University Medical Center; Erasmus Medical Center; St. Antonius Hospital

Not yet recruiting

Neoadjuvant Triple Treatment for Borderline Resectable Pancreatic Cancer (PREOPANC-5) (PREOPANC-5)

Borderline Resectable Pancreatic Cancer
Eli Lilly and Company

Recruiting

The Effect of Retatrutide Once Weekly on Cardiovascular Outcomes and Renal Function in Adults Living With Obesity (TRIUMPH-OUTCOMES)

Overweight and Obesity

United States, Australia, Italy, Hungary, Spain, Canada, Germany, Argentina, Belgium, Czechia, Greece, Israel, Austria, Brazil, Mexico, Netherlands, Romania, India, United Kingdom, Slovakia, Poland, Turkey, Puerto Rico, France, Denmark
Chunling Jiang

Not yet recruiting

Organ Dysfunction Change in Acute Necrotizing Pancreatitis Patients With Sepsis After Open Necrosectomy

Necrotizing Pancreatitis
Chunling Jiang

Not yet recruiting

Quality of Life Change in Patients Undergoing Parathyroidectomy With End-stage Renal Failure

Secondary Hyperparathyroidism | End Stage Renal Failure
Centro di Riferimento Oncologico - Aviano

Recruiting

A Study to Evaluate the Combination of Platinum-pemetrexed Based Chemotherapy Plus Lorlatinib in ALK Positive Non-Small Cell Lung Cancer (NSCLC) With Exclusively Extracranial Disease Progression on Lorlatinib (ALK-PPL)

Non Small Cell Lung Cancer Metastatic | ALK Gene Mutation

Italy
Coventry University
Newcastle University; University of Cambridge; University of Florence; Utrecht... and other collaborators

Not yet recruiting

Decision Support System for Diagnosis and Progression of Heart Failure (STRATIFYHF)

Heart Failure
University Hospital, Basel, Switzerland
University of Basel

Recruiting

REtinal Markers In Neuroinflammatory Diseases ("REMIND")

Multiple Sclerosis | Neuroinflammatory Diseases

Switzerland
Sixth Affiliated Hospital, Sun Yat-sen University

Recruiting

Dynamic Multi-omics Integration Model to Predict Neoadjuvant Therapy Response in Locally Advanced Rectal Cancer

Predictive Cancer Model | Pathologic Complete Response

China
Saint Petersburg State University, Russia

Recruiting

Study of the Rechallenge Concept in Patients With BRAF-positive Anaplastic Thyroid Cancer After Progression on Anti-BRAF Therapy

Anaplastic Thyroid Cancer

Russian Federation
The First Affiliated Hospital, Guangzhou University...

Not yet recruiting

A Single-arm Pilot Study of Tislelizumab Combined With Anlotinib in Patients With Advanced NSCLC With Driver-negative After Progression to Immunotherapy

Advanced NSCLC
Universidade Nova de Lisboa
iNOVA4Health, NOVA Medical School|Faculdade de Ciências Médicas, NMS|FCM,... and other collaborators

Recruiting

Intermediate Age-related Macular Degeneration - Multimodal Analysis and Longitudinal Study (Imaging4iAMD)

Age-Related Macular Degeneration

Portugal
Ferrer Internacional S.A.

Not yet recruiting

A Study to Assess the Efficacy, Safety, and Pharmacokinetics of FNP-223 to Slow Progression of Progressive Supranuclear Palsy (PSP)

Progressive Supranuclear Palsy
Medical University of Vienna
University of Zurich; Centre Hospitalier Universitaire Dijon; Fundacion Clinic... and other collaborators

Not yet recruiting

Personalized Monitoring of Non-foveal, Non-vision Compromising Atrophic Age-related Macular Degeneration With Artificial Intelligence and Identification of Disease Progression (APENNINES)

Age-Related Macular Degeneration | Geographic Atrophy
Medical University of Vienna
University of Zurich; Centre Hospitalier Universitaire Dijon; Fundacion Clinic... and other collaborators

Not yet recruiting

Personalised Monitoring of Early and Intermediate Age-related Macular Degeneration With Artificial Intelligence and Identification of Disease Progression (SUDETES)

Age-Related Macular Degeneration
Wuhan Union Hospital, China

Not yet recruiting

Study on Disease Progression and Nutritional Status in Bronchiectasis

Bronchiectasis

China
Qinghai Red Cross Hospital

Recruiting

Survival With Olanzapine in Patients With Locally Advanced or Metastatic Upper Gastrointestinal and Lung Cancer

Advanced Cancer | Progression Free Survival | Olanzapine

China
The First Affiliated Hospital with Nanjing Medical...

Recruiting

The Effects of Social Isolation and Social Interaction on the Risk of Dementia Progression and Brain Function in SCD (Subjective Cognitive Decline, SCD)

Alzheimer Disease | Mild Cognitive Impairment | MCI | SCD | Social Isolation | Subjective Cognitive Decline | AD

China
Philogen S.p.A.

Not yet recruiting

A Study With L19TNF in Combination With Lomustine in Patients With Glioblastoma at Progression or Recurrence (GLIOSTELLA)

Glioblastoma
University of Trieste

Recruiting

Multiparametric Home Telemonitoring of Patients With Chronic Obstructive Pulmonary Disease Exacerbation

COPD | COPD Exacerbation Acute

Italy
ECOG-ACRIN Cancer Research Group

Not yet recruiting

Identifying Findings on Brain Scans That Could Help Make Better Predictions About Brain Cancer Progression, The GABLE Trial

Glioblastoma, IDH-Wildtype
Peking University First Hospital

Recruiting

Fruquintinib Plus Everolimus as 2nd Line Therapy of ccRCC Patients Progressed Post IO and TKI Therapy

Renal Cell Carcinoma, Clear Cell, Somatic

China
Tenaya Therapeutics
Medical University of South Carolina; Johns Hopkins University; University of... and other collaborators

Recruiting

Non-interventional Study of Seroprevalence of Pre-existing Antibodies Against Adenovirus-associated Virus Vector (AAV9) and the Progression of Disease in Patients With Plakophilin 2 (PKP2)-Associated Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) (RIDGE)

Arrhythmogenic Right Ventricular Cardiomyopathy

United States, Italy, United Kingdom, France, Sweden, Germany
Medical College of Wisconsin

Not yet recruiting

Radiation Prior to TKI to Delay Progression in Advanced Driver-Mutated Non-small Cell Lung Cancers (RadiaNCe Lung X)

Non Small Cell Lung Cancer

United States
IRCCS San Raffaele

Recruiting

Advanced Radiotherapy (ART) in Gynecological Cancer Patients (GYN-ART) (GYN-ART)

Gynecologic Cancer | Radiotherapy Side Effect | Survivorship | Radiotherapy; Complications | Progression, Disease | Progression, Clinical

Italy
Bausch & Lomb Incorporated

Recruiting

A Study to Evaluate the Safety and Efficacy of the Bausch + Lomb Myopia Control Lens for the Correction of Myopic Ametropia and Slowing the Progression of Myopia in Children

Myopia

China
Hospices Civils de Lyon

Not yet recruiting

Contrast-enhanced Spectral Mammography (CESM) Early Quantitative Evaluation of Tumoral Response and Pathologic Complete Response Prediction for Localized Breast Cancer Treated by Neoadjuvant Chemotherapy (CERePred)

Breast Cancer

France
Gustave Roussy, Cancer Campus, Grand Paris
Daiichi Sankyo

Recruiting

Dose-Expansion Modular Study To Explore the Safety, Tolerability, and Anti-tumor Activity of HER3- DXd Monotherapy and Combinations in Patients With Inoperable Advanced Breast Cancer (ABC) After Progression on T-DXd (ICARUSBREAST02)

Advanced Breast Cancer | HER2-positive Metastatic Breast Cancer | Breast Cancer Metastatic | HER2 Low Breast Carcinoma

France
Fondazione IRCCS Ca' Granda, Ospedale Maggiore...
National Research Council

Recruiting

Using Tissue-based Spatial Data to Understand How Obesity-related Tumor Metabolites Fuel Prostate Cancer Progression (OBESITA'&PCa)

Obesity | Prostate Cancer | Prostate Adenocarcinoma | Prostate Neoplasm | Prostatic Neoplasm

Italy
Hellenic Institute for the Study of Sepsis

Recruiting

Clarithromycin Treatment to Prevent Sepsis Progression in CAP (REACT) (REACT)

Community-acquired Pneumonia

Greece
Medanta, The Medicity, India

Recruiting

Combining Gene Variants to Improve Risk Prediction for Metabolic (Dysfunction)- Associated Fatty Liver Disease and Its Progression to Cirrhosis in Indian Individuals With Type 2 Diabetes

Type2diabetes

India
icometrix
Bristol-Myers Squibb; Charite University, Berlin, Germany; Hoffmann-La Roche; Ruhr... and other collaborators

Not yet recruiting

Clinical Impact Through AI-assisted MS Care - A Retrospective Multi-center Observational Study. (RECLAIM)

Multiple Sclerosis | Clinically Isolated Syndrome | Radiologically Isolated Syndrome | NMO Spectrum Disorder | Myelin Oligodendrocyte Glycoprotein Antibody-associated Disease
Jasper Gerritsen
Massachusetts General Hospital; Universitaire Ziekenhuizen KU Leuven; University... and other collaborators

Recruiting

The RECSUR-study: Resection Versus Best Oncological Treatment for Recurrent Glioblastoma (ENCRAM 2302) (RECSUR)

Glioblastoma | Glioblastoma Multiforme | Recurrent Glioblastoma | Glioblastoma, IDH-wildtype | Glioblastoma Multiforme, Adult | Glioblastoma Multiforme of Brain | Astrocytoma of Brain | Astrocytoma, Malignant

United States, Germany, Netherlands, Switzerland, Belgium
University of Louisville

Recruiting

Aggressive Risk-Prevention Therapies for Coronary Atherosclerotic Plaque (ART-CAP) (ARTCAP)

Coronary Artery Disease | Atherosclerosis | Heart Attack

United States
The Hong Kong Polytechnic University
The University of Hong Kong

Recruiting

Pharmacological and Non-pharmacological Treatment Effects on Children With Different Predicted Myopia Progression Rate

Myopia

Hong Kong
Number 2 Children's Hospital, Ho Chi Minh City

Recruiting

Genotype, Phenotype, and Disease Progression of Developmental Epileptic Encephalopathy With Onset Before 2 Years of Age

Child Development | Epilepsy; Seizure | Gene Abnormality | Early Onset Disorder

Vietnam
Erasmus Medical Center
Massachusetts General Hospital; Universitaire Ziekenhuizen KU Leuven; University... and other collaborators

Recruiting

The RECMAP-study: Resection With or Without Intraoperative Mapping for Recurrent Glioblastoma (RECMAP)

Glioblastoma | Brain Neoplasms | Recurrent Glioblastoma | Recurrent Adult Brain Tumor | Glioblastoma, IDH-wildtype | Glioblastoma Multiforme of Brain | Brain Neoplasms, Adult, Malignant | Astrocytoma, Malignant | Brain Neoplasms, Adult

United States, Germany, Switzerland, Belgium, Netherlands
Jie Li

Recruiting

Study of Natural Course Progression of Diabetic Retinopathy

Biomarkers of Diabetic Retinopathy

China
IRCCS San Raffaele

Recruiting

RRMS: Disease PROgression and Myeloid Profiling After Bone Marrow TRANSPLANTation and Second Line Therapies (TRANSPLANTPRO)

Multiple Sclerosis

Italy
Ain Shams University

Not yet recruiting

Low Dose Atropine Eye Drops in Myopic Egyptian Children (LAMP)

Myopia Progression | Axial Length, Eye | Sclera Thickness

Egypt

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