Search clinical trials for: Poor Metabolizers

Total 1452 results

Boehringer Ingelheim

Completed

Drug Drug Interaction Trial With Strong CYP3A4 Inhibitor (Itraconazole) in CYP2C19 Extensive Metabolizers and Poor Metabolizers

Healthy

Korea, Republic of
Sanofi

Completed

A Study to Evaluate Pharmacokinetic Parameters of Eliglustat in Healthy Volunteers Who Are CYP2D6 Extensive or Poor Metabolizers

Gaucher's Disease

United States
Organon and Co

Completed

Safety of Desloratadine in Children With Allergy Sensitivity and Chronic Hives, Who Are Poor Metabolizers of Desloratadine (Study P02994)

Chronic Idiopathic Urticaria | Atopy
Radboud University Medical Center

Completed

PharmacoKINEtics of TAMoxifen and Its Metabolites in Breast Cancer Patients: the Influence of a Dose Increase in Phenotypic Poor Metabolizers of CYP2D6 (KINETAM) (KINETAM)

Breast Cancer

Netherlands
Chonbuk National University Hospital

Completed

Efficacy and Safety of Angelica Gigas N. Extract on Improvement of Hyperglycemia

Hyperglycemia

Korea, Republic of
Minerva Neurosciences

Completed

A Pharmacokinetic Study of MIN-101 and Its Metabolites in Healthy Subjects to Compare MIN-101 in Poor and Extensive Metabolizers

Healthy Subjects

Ireland
Tufts University

Completed

Absorption Kinetics of Polyphenols in Angel's Plant (Angelica Keiskei)

Oxidative Stress

United States
Astellas Pharma Inc

Completed

To Compare Blood and Urine Concentrations of Mirabegron (YM178) in Healthy Poor or Extensive Metabolizers for CYP2D6 and to Assess the Effect of Mirabegron on the Metabolism of Metoprolol

Healthy Subjects | Pharmacokinetics of Mirabegron

Netherlands
Pfizer
Medivation, Inc.

Completed

A Phase I Study To Estimate The Effect Of Ketoconazole And Omeprazole On The Pharmacokinetics Of Dimebon In Healthy Subjects Who Are Normal Or Poor CYP2D6 Metabolizers

Alzheimer's Disease | Huntington's Disease

United States
AstraZeneca

Completed

Study in Taiwanese Subjects Identified as CYP2C19 Poor and Extensive Metabolizers Receiving Rosuvastatin

CYP2C19 Poor | Extensive Metabolizers

Taiwan
ArQule, Inc. (a wholly owned subsidiary of Merck...

Completed

A Study of ARQ 197 in Healthy Volunteers to Assess the Pharmacokinetic (PK) Profile in Extensive and Poor Metabolizers as Defined by Cytochrome P450 2C19 (CYP 2C19) Genotype

Healthy

United States
Fluidx Medical Technology, Inc.
Bright Research Partners

Not yet recruiting

Evaluation of a Simple-Prep Controlled Embolic (GPX)

Renal Cell Carcinoma | Embolism | Bone Tumor | Portal Vein Embolism | Renal Angiomyolipoma | Vascular Tumor
Assistance Publique Hopitaux De Marseille

Not yet recruiting

Identification of Markers of Poor Clinical Prognosis in Sepsis by Epigenetic Analysis (EPISEPSIS)

Sepsis | Septic Shock | Sepsis Syndrome
Institutul de Urgenţă pentru Boli Cardiovasculare...

Recruiting

Portal Vein Pulsatility Index to Assess Fluid Intolerance

Venous Congestion

Romania
Centrum Clinic IVF Center

Not yet recruiting

BEst Size for Ovulation Triggering in Poseidon 4 Patients (BEST 4 Study) (BEST)

Fertilization | Fertilization in Vitro
Columbia University
United States Department of Agriculture (USDA); California Walnut Commission

Not yet recruiting

Mechanistic Effect of Walnut Consumption on Sleep Quality

Poor Sleep Quality

United States
National Cancer Institute (NCI)

Not yet recruiting

Measuring if Immunotherapy Plus Chemotherapy is Better Than Chemotherapy Alone for Patients With Aggressive Poorly Differentiated Sarcomas

Undifferentiated Pleomorphic Sarcoma | Stage III Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8 | Stage IV Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8
Fu Jen Catholic University

Not yet recruiting

3D Port-A Catheter Model for New Staff

Cancer | Personal Satisfaction

Taiwan
Fu Jen Catholic University

Recruiting

Effects of a 3D-Printed Port-A Catheter Model Training Course

Cancer | Patient Satisfaction

Taiwan
European Institute of Oncology

Recruiting

PrognostIc and Predictive Factors in Unresectable Locally Advanced NEC and MANEC (NIRVANA)

Neuroendocrine Carcinoma

Italy
Maastricht University Medical Center

Not yet recruiting

Three Channel Food Concept: the Effect Meal Service on Food Intake During Hospitalization

Protein-Energy Malnutrition | Nutrition Poor

Netherlands
Shandong Suncadia Medicine Co., Ltd.

Not yet recruiting

Efficacy and Safety of HRS-7535 Tablets in T2DM Subjects Poorly Controlled With Metformin and SGLT2i.

Type 2 Diabetes
University of Rome G. Marconi
University of Bologna; University of the Italian Switzerland

Not yet recruiting

Poor Sleep During Pregnancy as Risk Factor for Post-partum Stress and Mental Health (MOTHERS)

Stress | Insomnia | Postpartum Depression

Italy
Rigshospitalet, Denmark
Slagelse Hospital; Technical University of Denmark

Recruiting

Human-AI Collaborative Intelligence for Improving Fetal Flow Management

Healthy

Denmark
Texas Tech University

Not yet recruiting

Mitochondrial DNA Signatures of Poor Aerobic Exercise Trainability in Young Adults Born Preterm

Preterm Birth
Senti Biosciences

Recruiting

SENTI-202: Off-the-shelf Logic Gated CAR NK Cell Therapy in Adults With CD33 and/or FLT3 Blood Cancers Including AML/MDS

AML/MDS | CD33 Expressing Hematological Malignancies | FLT3 Expressing Hematological Malignancies

United States, Australia
Mayo Clinic

Not yet recruiting

Pharmacogenetic Panel to Prevent Adverse Drug Reactions in Daily Primary Care Practice: (PREPARE-Mayo)

Side Effect of Drug | Pharmacogenomic Drug Interaction | Drug Metabolism, Poor, CYP2D6-Related | Ineffective Drug Action | Drug Metabolism, Poor, CYP2C19-Related

United States
Shanghai Shenqi Medical Technology Co., Ltd

Not yet recruiting

Efficacy and Safety of Intraparenchymal Portal Vein Covered Stents in Treating Portal Hypertension and Its Complications

Portal Hypertension

China
University of Yalova

Recruiting

The Effect of Breathing Exercise on Sleep and Stress Levels in Women With Breast Cancer Receiving Chemotherapy Treatment

Women Receiving Chemotherapy | 18 Years of Age and Above | Women With High Stress Levels | Women With Poor Sleep Quality

Turkey
Shanghai Zhongshan Hospital
Tongji Hospital; Renmin Hospital of Wuhan University; ShuGuang Hospital; Shanghai...

Not yet recruiting

Nadroparin Versus TIPS in Cirrhotic Patients With Refractory Asymptomatic PVT

Portal Vein Thrombosis
University of Maryland, Baltimore
Inari Medical

Not yet recruiting

Large-Bore Mechanic Thrombectomy for the Treatment of Symptomatic Portomesenteric Vein Thrombosis

Thrombosis | Thrombectomy | Portal Vein
National University of Malaysia

Recruiting

GREM1, HAS2 and PTGS2 Gene Expression Following the in Vitro Maturation (IVM)

in Vitro Maturation | Cumulus Cell | Increased Oocyte Death | GREM1 Gene Mutation

Malaysia
Eli Lilly and Company

Recruiting

A Study to Investigate the Effect of Lepodisiran on the Reduction of Major Adverse Cardiovascular Events in Adults With Elevated Lipoprotein(a) - ACCLAIM-Lp(a)

Elevated Lp(a) | Atherosclerotic Cardiovascular Disease (ASCVD)

United States, Australia, Spain, Canada, Argentina, China, Italy, France, Japan, Taiwan, Korea, Republic of, Denmark, Germany, Hungary, Israel, Austria, Belgium, Netherlands, Brazil, Mexico, Romania, United Kingdom, Greece, Czechia, Poland and more
Linkoeping University
Ostergotland County Council, Sweden; Fibromyalgia foundation

Not yet recruiting

Nutrition Care in Patients Living With Chronic Pain

Overweight and Obesity | Pain, Chronic | Mobile Phone Use | Nutrition Poor
Sohag University
Randers Regional Hospital

Recruiting

Oral Versus Intravenous Antibiotic Prophylaxis Before Obstetric and Gynecological Procedures

Site Infection

Egypt
National Cancer Institute, Malaysia

Recruiting

Feasibility, Acceptability, and Effectiveness of an Individualized Plant-based (iPLANT) Diet Plan in Colorectal Cancer: Mixed Method Embedded Design

Quality of Life | Colorectal Cancer | Nutrition Poor | Gastrointestinal Complication

Malaysia
Ruijin Hospital
Intuitive Surgical

Recruiting

Valuate the Clinical Performance and Safety of da Vinci SP Surgical System

Thoracic Surgery | da Vinci SP Surgical System

China
Hvidovre University Hospital
University of Aarhus; Danish Lung Association

Recruiting

Is a Collective Person-centered Dialogue Intervention for Hospitalised COPD Patients Feasible? (COPE-D)

Relatives | Physical Inactivity | Nutrition Poor | COPD Exacerbation Acute

Denmark
Shanghai Changzheng Hospital
Shanghai Zhongshan Hospital; The First Affiliated Hospital of Guangzhou Medical... and other collaborators

Recruiting

Extraperitoneal SINgle-port rObotic-assisted Radical Prostatectomy (RARP) Versus Transperitoneal Multi-port RARP in the Treatment Of Prostate Cancer (SINO-TOP)

Prostate Adenocarcinoma | Localized Prostate Carcinoma

China
University of Illinois at Chicago

Recruiting

Prostate Single Port & Laser Enucleation Comparison Trial

Prostate Hyperplasia

United States
Bedaya Hospital

Not yet recruiting

Dydrogesterone Versus GnRH Antagonist in Poor Responders Undergoing Double Ovarian Stimulation

Infertility

Egypt
Li Xiao Wei

Not yet recruiting

HAIC Combine Tislelizumab and Lenvatinib in the Treatment of HCC With Type IV (Vp4) Portal Vein Tumor Thrombus (HAI-TL) (HAI-TL)

Hepatocellular Carcinoma With PVTT

China
Ggz Oost Brabant

Recruiting

Depression and Suicide Prevention in Adolescents Attending Special Schools (STORM)

Depressive Symptoms

Netherlands
Korea University Guro Hospital

Not yet recruiting

SP Robotic Versus VATS Anatomical Pulmonary Resection for Patients With NSCLC (SPORTS)

Lung Cancer | Robotics
Shanghai Changzheng Hospital

Recruiting

Allogeneic Regenerative Islet Transplantation for the Treatment of Brittle Type 1 Diabetes Mellitus

Brittle Type 1 Diabetes Mellitus

China
Ruijin Hospital

Recruiting

A Real-World Study to Evaluate the Clinical Performance and Safety of da Vinci SP Surgical System for Single-Port Urological Surgeries (SPiM-RWS-URO)

Urological Surgeries

China
INFINITT Healthcare
Korea Medical Device Development Fund

Recruiting

Evaluating AI-Gatekeeper Software in Coronary Artery Stenosis Screening: A Multicenter RCT (AIGatekeeper)

Coronary Artery Disease | Diagnosis

Korea, Republic of
ShiCang Yu
Xinqiao Hospital of Chongqing

Not yet recruiting

Mesenchymal Stem Cells for Treatment of Poor Graft Function After Allogeneic Hematopoietic Stem Cell Transplantation

MSC

China
Seoul National University Hospital

Recruiting

Radioembolization as a Spearhead Treatment of Hepatocellular Carcinoma With Localized Portal Vein Tumor Thrombosis (RESOLVE)

Hepatocellular Carcinoma

Korea, Republic of
Cure 51
Centre Leon Berard; Charite University, Berlin, Germany; Gustave Roussy, Cancer... and other collaborators

Recruiting

Analyzing and Solving Exceptional Long-term Survivors in Solid Tumors With Poor Prognosis (ROSALIND)

Pancreas Adenocarcinoma | Small-cell Lung Cancer | Glioblastoma, IDH-wildtype

France

Search clinical trials for: Poor Metabolizers

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