Search clinical trials for: pathogen inactivation

Total 727 results

Cerus Corporation

Recruiting

INTERCEPT Blood System for RBCs Study in Regions at Potential Risk for Zika Virus Transfusion-Transmitted Infections (RedeS)

Anemia

United States, Puerto Rico
Aadi Bioscience, Inc.

Active, not recruiting

Phase 2 Basket Trial of Nab-sirolimus in Patients With Malignant Solid Tumors With Pathogenic Alterations in TSC1/TSC2 Genes (PRECISION 1)

Malignant Solid Neoplasm | Neoplasms | Cancer | Neoplasm Metastasis | Solid Tumor | Metastatic Cancer | Metastasis | Advanced Solid Tumor | Metastatic Solid Tumor | Advanced Cancer | Tumor | Malignant Neoplasm | Malignant Tumor | Tumors | Cancer Metastatic | Tumor, Solid | Malignant Solid Tumor | TSC | TSC1 | TSC2 | Metastatic Neoplasm

United States, Korea, Republic of, Puerto Rico
Swiss Transfusion SRC
Cerus Corporation

Withdrawn

INTERCEPT Safety Evaluation on Whole Blood (POINT1africa)

Safety Issues
Cerus Corporation

Active, not recruiting

Study to Evaluate the Efficacy & Safety of the INTERCEPT Blood System for RBCs in Complex Cardiac Surgery Patients (ReCePI)

Anemia

United States
Cerus Corporation

Terminated

A Prospective, Open Label, Phase 1 Safety Study of Passive Immune Therapy During Acute Ebola Virus Disease Using Transfusion of INTERCEPT Plasma Prepared From Volunteer Donors Who Have Recovered From Ebola Virus Disease

Acute Ebola Virus Disease

United States
National Blood Center Foundation, Hemolife

Unknown

Inactivated Convalescent Plasma as a Therapeutic Alternative in Patients CoViD-19

Infections, Coronavirus

Colombia
Swiss Transfusion SRC
Cerus Corporation

Withdrawn

INTERCEPT Safety Evaluation in Anemic Patients (POINT1africa)

Anemia
Federal Research Institute of Pediatric Hematology...

Completed

Clinical Use of Pathogen Reduced Red Blood Cell Suspension

Hematologic Diseases | Oncologic Disorders

Russian Federation
Cerus Corporation
American National Red Cross

Completed

A Prospective, Open Label, Treatment Use Study of Patient Safety Following Transfusion of INTERCEPT Platelet Components (TRUE)

Dengue Virus | Chikungunya Virus

Puerto Rico
Sanquin Research & Blood Bank Divisions
Terumo BCT

Completed

Pathogen Reduction Evaluation & Predictive Analytical Rating Score (PREPAReS)

Thrombocytopenia

Netherlands, Norway, Canada
Cerus Corporation

Terminated

A Randomized, Multi-center, Open-label, Paired Controlled, Crossover In Vivo Study

Healthy

United States
Cerus Corporation

Completed

A Controlled, In Vivo, Pilot Study to Assess the Recovery and Survival of Radiolabeled Autologous INTERCEPT Treated 7-Day Stored Apheresis Platelet Components in 35% Plasma and 65% InterSol and 7-Day Stored Apheresis Platelet Components in 100% Plasma

Healthy
Terumo BCTbio
U.S. Army Medical Research and Development Command

Completed

Inactivation of Whole Blood With Mirasol (IMPROVEII)

Focus of Study: Radiolabel Recovery and Survival of RBCs

United States
Cerus Corporation

Completed

Efficacy and Safety Study of Platelets Treated for Pathogen Inactivation and Stored for Up to Seven Days (TESSI)

Thrombocytopenia

United Kingdom
Université Catholique de Louvain

Recruiting

New Perspectives in Adenomyosis Pathogenesis With Epigenetic Analysis and miRNAs (ADENO-MIRNA)

Adenomyosis

Belgium
Centre Hospitalier Universitaire de la Réunion

Recruiting

Pathogenicity of Species of the Achromobacter Genus in Patients From Reunion Island With Cystic Fibrosis (ACHROMO-MUCO)

Cystic Fibrosis

Réunion
Zhujiang Hospital

Recruiting

Investigation on the Detection Rate of Pathogenic Viruses in Feces of Parenteral Infected Individuals

Virus Infections

China
Peking University
Peking University Third Hospital

Not yet recruiting

Unraveling the Pathogenesis of Pruritus in Intrahepatic Cholestasis of Pregnancy

Intrahepatic Cholestasis of Pregnancy

China
Regeneron Pharmaceuticals

Not yet recruiting

First in Human (FIH) Study of ALN-SOD in Adult Participants With Amyotrophic Lateral Sclerosis Associated With Mutation in the SOD1 Gene (SOD1-ALS)

Amyotrophic Lateral Sclerosis (ALS) | Mutation in the Superoxide Dismutase-1 (SOD1) Gene
Beneficência Portuguesa de São Paulo
Merck Sharp & Dohme LLC

Not yet recruiting

Ceftolozane/Tazobactam Versus Meropenem for Febrile Neutropenia on Patients Colonized With or at Risk for Infection With Extended Spectrum Beta Lactamase - Producing Pathogens (CLEMENT)

Febrile Neutropenia

Brazil
Peking University Third Hospital

Recruiting

Lysophosphatidylglycerol in Asthma Pathogenesis

Asthma

China
IRCCS Burlo Garofolo

Recruiting

Transcriptome Analysis in Idiopathic Nephrotic Syndrome: Steroid Responsiveness

Nephrotic Syndrome

Italy
Meyer Children's Hospital IRCCS

Recruiting

Epidemiological Study on Invasive Bacterial Diseases

Invasive Bacterial Diseases (IBD)

Italy
Queen Mary University of London
Barts & The London NHS Trust; Quadram Institute Bioscience

Recruiting

Accuracy of Metagenomic Blood Sampling to Identify Pathogen in Infective Endocarditis Patients (AMetIP)

Infective Endocarditis

United Kingdom
Ospedale San Raffaele

Not yet recruiting

Detection of Lipoarabinomannan in Urine Evaluation of the STANDARDTMF TBLAMFIA and Its Impact on the Initial TB Diagnosis (uLAMTBFIA)

Tuberculosis | Diagnoses Disease

Italy
University of Minnesota

Recruiting

Surgical Site Infections and the Microbiome: Understanding the Pathogenesis of Surgical Site Infections

Open GI Surgery

United States
Regeneron Pharmaceuticals

Not yet recruiting

A Trial to Learn if Linvoseltamab is Safe and Works in Adults With Relapsed or Refractory Systemic Light Chain Amyloidosis (AL Amyloidosis) (LINKER-AL2)

Relapsed/Refractory Systemic Light Chain Amyloidosis
IBS-80, LLC

Recruiting

IBS Skin Patch Test Food Allergy Study

Irritable Bowel Syndrome

United States
Zhejiang University
Beijing YouAn Hospital; Beijing Ditan Hospital; Huashan Hospital; Qilu Hospital...

Not yet recruiting

A Clinical Cohort Study on the Pathogen Spectrum of Hepatic Virus-caused Cirrhosis Complicated With Infection

Liver Cirrhosis
Zhejiang University
Beijing YouAn Hospital; Beijing Ditan Hospital; Huashan Hospital; Qilu Hospital...

Not yet recruiting

A Multicenter Prospective Clinical Cohort Study on the Pathogen Spectrum of HIV/AIDS Complicated With Infection

HIV Infections | Acquired Immunodeficiency Syndrome
Zhejiang University
Beijing YouAn Hospital; Beijing Ditan Hospital; Huashan Hospital; Qilu Hospital...

Not yet recruiting

A Cohort Study on the Pathogen Spectrum of Liver Transplant Recipients Complicated With Infection

Liver Transplantation | Transplant Recipients
Washington University School of Medicine

Recruiting

DORA and LP in Alzheimer's Disease Biomarkers

Alzheimer Disease

United States
Zhejiang University
Beijing YouAn Hospital; Beijing Ditan Hospital; Huashan Hospital; Qilu Hospital...

Not yet recruiting

A Multicenter Prospective Clinical Cohort Study on the Pathogen Spectrum of Severe Hepatitis (Liver Failure) Complicated With Infection

Liver Failure
Sohag University

Not yet recruiting

Evaluation of Pyroptosis-related Indicators in the Pathogenesis of Vitiligo:Across-sectional Comparative Study

Vitiligo
The Methodist Hospital Research Institute
M.D. Anderson Cancer Center; National Institute of Allergy and Infectious Diseases... and other collaborators

Recruiting

Dynamics of Colonization and Infection by Multidrug-Resistant Pathogens in Immunocompromised and Critically Ill Patients (DYNAMITE)

Antibiotic Resistant Infection | Clostridium Difficile | Antimicrobial Drug Resistance | Carbapenem-Resistant Enterobacteriaceae Infection | Vancomycin Resistant Enterococci Infection | Vancomycin-Resistant Enterococcal Infection | Carbapenem Resistant Bacterial Infection | Extended Spectrum Beta-Lactamase...

United States
Hvivo
Pfizer

Recruiting

Dose, Safety, and Pathogenicity of a New Influenza B Strain

Influenza B

United Kingdom
Columbia University

Recruiting

Role of Insulin Action in Psoriasis Pathogenesis

Psoriasis | Insulin Resistance | PreDiabetes | Plaque Psoriasis | Overweight and Obesity

United States
National Cancer Institute, Naples

Recruiting

Identification of the Pathogenetic Mechanisms Underlying Squamous Cell Carcinomas

Squamous Cell Carcinoma of the Head and Neck | Squamous Cell Carcinoma of the Anus

Italy
Ospedale San Raffaele

Recruiting

Exhaled Breath Aerosol for the Etiological Diagnosis of Respiratory Tract Infections: a Pilot Study (AEROPLEX)

Respiratory Diseases

Italy
Hospices Civils de Lyon

Recruiting

Evaluation of the Performance of the IDBIORIV Method in Pathogen Identification and Antibiotic Susceptibility Testing in Patients With Sepsis (IDBIORIV)

Sepsis

France
Shanghai Zhongshan Hospital

Recruiting

The Pathogenesis and Prognostic Factors of Lymphoma

Lymphoma | Hodgkin Lymphoma | Non-hodgkin Lymphoma

China
Nanfang Hospital, Southern Medical University

Recruiting

Prospective Study on the Efficacy and Safety of Bronchoalveolar Lavage Combined With Pathogen Metagenomic Sequencing Technology in the Diagnosis of Immune Checkpoint Inhibitor Associated Pneumonia

Immune Checkpoint Inhibitor Associated Pneumonia

China
Oscar Gerardo Arrieta Rodríguez

Recruiting

Pathogenic Variants in Genes Associated With Lung Adenocarcinoma

Lung Adenocarcinoma

Mexico
Duke University
National Institute of Allergy and Infectious Diseases (NIAID)

Recruiting

Pneumonia Direct Pilot (PDP)

Pneumonia, Bacterial | Ventilator Associated Pneumonia

United States
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Not yet recruiting

Detection of Pathogen and Antibiotic Resistance Genes by Targeted Next-Generation Sequencing in ICU Patients.

Infections | Critical Illness | Diagnosis
Johns Hopkins University
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

Role of Senescent Cells in Uterine Fibroid Pathogenesis (SOUL Study) (SOUL)

Leiomyoma | Fibroid

United States
Virginia Polytechnic Institute and State University
University of North Carolina, Chapel Hill; East Tennessee State University; Ballad...

Recruiting

Rural Appalachia Pilot Water Treatment Trial

Enteric Pathogens | Water-Related Diseases | Exposure to Chemical Pollution

United States
Lexeo Therapeutics

Recruiting

Gene Therapy for ACM Due to a PKP2 Pathogenic Variant

Arrhythmogenic Cardiomyopathy | PKP2-ACM | PKP2-ARVC

United States
International Centre for Diarrhoeal Disease Research...
Centers for Disease Control and Prevention; Institute of Epidemiology, Disease...

Recruiting

Fungal Surveillance in Bangladesh

Invasive Fungal Infections

Bangladesh
Federico II University

Recruiting

The Potential Role of Compounds Derived From Ultra-processed Foods in Pathogenesis of Eosinophilic Esophagitis

Esophagitis, Eosinophilic

Italy

Search clinical trials for: pathogen inactivation

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